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Ointment for eliminating wind-damp, antiinflammation and ease pain as well as its preparing method

An anti-inflammatory analgesic and ointment technology, applied in the direction of anti-inflammatory agent, ointment delivery, non-central analgesic, etc., can solve the problems of unstable quality, strong toxicity, insufficient processing, etc., achieve remarkable analgesic effect, high content high effect

Inactive Publication Date: 2004-03-10
FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Excessively processed, weak medicinal effect; insufficiently processed, strong toxicity, easy to cause poisoning reaction
In addition, when aconitum alkaloids are injected, the pain is severe and long-lasting, and the patient's compliance is poor; oral administration has certain irritation to the gastrointestinal tract, and the first-pass effect is obvious, so the injection or oral administration of processed products is not ideal. Way
[0005] Aconitum medicinal raw products have been used for external use in ancient times. Generally, they are external preparations made of simple processing of medicinal materials. The dosage is large, the quality is unstable, and the content of active ingredients is low, so the curative effect is also unstable.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Aconitum herbal extract 0.5g

[0042] Carbomer 2g

[0043] Appropriate amount of sodium hydroxide

[0044] Ethanol 10g

[0045] Glycerin 15g

[0046] Eucalyptus oil 2g

[0047] Tween 80 0.5g

[0048] Ethylparaben 0.2g

[0049] water up to 100g

[0050] Get above-mentioned components and consumption, prepare according to following method and steps,

[0051] (1) Take carbomer and add 2 / 3 of the formula amount of water to make it fully swell. After the carbomer swells, add sodium hydroxide to adjust the consistency.

[0052] (2) Mix eucalyptus oil, Tween 80, and ethylparaben evenly, add a small amount of water, stir to emulsify, add to (1) and stir evenly.

[0053] (3) Take the extract of aconitum medicinal materials, add ethanol and glycerin, stir well to make it evenly dispersed.

[0054] (4) Add (3) to (1), stir well, add water to a sufficient amount, and stir evenly.

Embodiment 2

[0056] Aconitum herbal extract 2g

[0057] Hydroxyethylcellulose 5g

[0058] Ethanol 15g

[0059] Glycerin 15g

[0060] Ethylparaben 0.5g

[0061] Menthol 4g

[0062] water up to 100g

[0063] Get above-mentioned components and consumption, prepare according to following method and steps,

[0064] (1) Take hydroxyethyl cellulose and glycerin and stir well, add water to make it fully swell.

[0065] (2) Take the extracts of aconitum medicinal materials, menthol and ethylparaben, add ethanol, stir well to dissolve or evenly disperse.

[0066] (3) Add (2) to (1), stir well, add water to a sufficient amount, and stir evenly.

Embodiment 3

[0068] Aconitum herbal extract 0.8g

[0069] Oleic acid 5g

[0070] Appropriate amount of liquid paraffin

[0071] Add Vaseline to 100g

[0072] Get above-mentioned components and consumption, prepare according to following method and steps,

[0073] Take the extract of aconitum medicinal materials and oleic acid, put them in a mortar, add liquid paraffin to grind, add petroleum jelly in stages, mix and grind until uniform.

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PUM

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Abstract

An antiiflammatory, antirheumatic and antalgic ointment contains the extract of Chinese monkshood rhizome, matrix, percutaneous absorption promoter, and antiseptic. Its advantages are high curative effect and low by-effect.

Description

technical field [0001] The invention belongs to the field of pharmacy, and relates to an ointment for anti-inflammation, analgesia and rheumatism dispelling, in particular to an ointment containing extracts of aconitum medicinal materials and a preparation method thereof. technical background [0002] Aconite medicinal materials include Aconitum Aconitum, Aconitum Aconitum and Aconitum etc. Aconitum kusnezoffii Reichb. is recorded in the first part of the "Chinese Pharmacopoeia" 2000 edition as the dry root tuber of Aconitum kusnezoffii Reichb., a plant of the Ranunculaceae family. In addition, the tubers of A.chinese Paxt., A.delavayi Franch., A.vilmorinianum Kom. and A.bulleyanum Diels of the same genus are also used as "Caowu". In Sichuan and other places, wild Aconitum aconitum is used as Aconitum aconitum. Chuanwu is the mother root of Aconitum aconitum A.carmichaeliDebx., and its daughter root is aconite. [0003] Aconitum medicinal materials are very poisonous. It...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K31/403A61P29/00
Inventor 黄建明郭济贤翁伟宇陈万生
Owner FUDAN UNIV
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