The invention relates to a vonoprazan fumarate-containing tablet and a determination method for a dissolution rate thereof. The vonoprazan fumarate-containing tablet provided by the invention is composed of the following components in parts by weight: 10-15 parts of vonoprazan fumarate, 65-75 parts of mannitol, 2-5 parts of organic acid, 2-4 parts of hydroxy propyl cellulose, 8-12 parts of microcrystalline cellulose, 2-6 parts of croscarmellose sodium, 0.5-2 parts of magnesium stearate, 3-4 parts of coating powder and 0.2-1.0 part of polyethylene glycol. According to the tablet prepared by using the method, a damp-heat process is avoided; the granules of the tablet are good in flowability and compressibility, and the tablet is free of sticking, smooth in surface, qualified in friability and stable in tablet weight; after coating is completed, an aqueous polyethylene glycol solution is used for polishing treatment, so the appearance of the tablet is more glossy, a better moisture insulation effect is achieved on the tablet, and the dissolution behavior of the tablet is not influenced.