The invention provides composition with functions of reducing hypertension, hyperglycemia and hyperlipidemia. The composition comprises components in parts by weight as follows: 65 parts of soybean protein, 0.6 parts of fish collagen protein, 4.5 parts of dried skim milk, 11 parts of dietary fiber, 0.9 parts of whey protein, 0.5 parts of wheat albumin, 1.3 parts of cereal powder, 0.9 parts of sargassum fusiforme powder, 0.1 parts of beer yeast powder, 0.03 parts of rice germ / soybean fermentation extract powder, 0.01 parts of Chinese yam extract powder, 0.01 parts of hawthorn fruit extract powder, 0.01 parts of salmon milt extract powder, 3 parts of potassium chloride, 1 part of silicon dioxide, 0.7 parts of L-methionine, 0.2 parts of a sweetening agent, 0.7 parts of vitamins and 9.54 parts of cocoa extract powder. The invention further provides a preparation method of the composition. The composition has the good effects of reducing hypertension, hyperglycemia and hyperlipidemia and decreasing morbidity of fatty liver, diabetes mellitus and cardiovascular and cerebrovascular diseases and the like, is convenient to take and avoids side effects.