Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
52 results about "Original research" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Original research is research that is not exclusively based on a summary, review or synthesis of earlier publications on the subject of research. This material is of a primary source character.
Preparation method of stable cefuroxime sodium
InactiveCN102838622ALess impuritiesImprove stabilityOrganic chemistryCefuroxime SodiumCrystallization
The invention belongs to the technical field of medicine, relates to a preparation method of cephalosporin, and more specifically relates to a preparation method of a stable cefuroxime sodium. According to the invention, a process control technique and a multiscale simulation technology are utilized to conduct on-line crystallization control of cefuroxime sodium, so as to obtain a cefuroxime sodium product with stable quality and crystal form, and moderate particles. The quality and especially the stability of the product are improved greatly, and product quality achieves a same level as that of ''Xilixin'' from an original researching factory.
Owner:SHANXI WEIQIDA PHARMA IND
Improved anti-VEGFR (vascular endothelial growth factor receptor)-2 monoclonal antibody
ActiveCN106674349AHigh affinityInhibit bindingSenses disorderAntibody mimetics/scaffoldsAbnormal tissue growthDisease
The invention relates to the technical field of biomedicine, in particular to an improved anti-VEGFR (vascular endothelial growth factor receptor)-2 monoclonal antibody and application. On the basis of the original research, a new phage antibody library is designed by computer-aided simulation by taking two of them with the highest affinity as templates, and improved heavy chain variable region and light chain variable region amino acid sequences are obtained by multi-round screening; the affinity and biological activity of the anti-VEGFR 2 monoclonal antibody are higher than those of the original antibody. The anti-VEGFR 2 monoclonal antibody obtained by the invention has relatively high affinity, can inhibit the binding of VEGFR-2 and a ligand VEGF thereof in vitro and has good biological activity, and can be used for the treatment of tumors, macular degeneration and other diseases caused by neovascularization.
Owner:BEIJING DONGFANG BIOTECH
Flupentixol and melitracen medicinal composition and preparation thereof
ActiveCN109674754AImprove stabilityLower levelOrganic active ingredientsNervous disorderMELITRACEN HYDROCHLORIDEAntioxidant
The invention relates to a flupentixol and melitracen medicinal composition and a preparation thereof, and belongs to the technical field of pharmaceutical preparations. The flupentixol and melitracenmedicinal composition is prepared from flupentixol dihydrochloride, melitracen hydrochloride and an antioxidant. The flupentixol and melitracen medicinal composition disclosed by the invention has the advantages that by adding the antioxidant, the stability of a flupentixol and melitracen compound preparation can be effectively enhanced, and impurities such as Lu28-159 and trifluoromethyl thioxanthone produced by degrading flupentixol can be effectively controlled, so that impurity level is reduced and the safety and the effectiveness of a product are ensured; flupentixol and melitracen medicinal tablets prepared by the preparation method disclosed by the invention have similar in-vitro dissolution behavior and bioequivalence with original research tablets Deanxit.
Owner:GUANGDONG SCI FINDER PHARMA TECH CO LTD +1
Managing document unit references to improve collaborative document editing
InactiveUS20150363378A1Facilitate collaborative review of a documentNatural language data processingTransmissionArray data structureDocumentation procedure
An approach is provided for managing a display of document unit references. Units of an original version of a document and original references to the units are stored in nodes of a data structure. Responsive to an insertion of a new unit at a location in the document, a new node is inserted into the data structure at a corresponding location, or responsive to a deletion of a unit at the location in the document, a node is deleted from the data structure at the corresponding location. Unit(s) of the updated document resulting from the insertion or deletion are associated to respective original reference(s) in the data structure. During a conference between an editor and other participant(s), a display is generated and presented to the editor. The display includes the unit(s) of the updated document, current reference(s) to the unit(s), and the original reference(s) associated with the unit(s).
Owner:IBM CORP
Preparation method of edaravone injection
ActiveCN107823128AImprove stabilityOrganic active ingredientsPharmaceutical delivery mechanismEdaravone InjectionCysteine Hydrochloride
The invention relates to the field of medicines, in particular to a preparation method of an edaravone injection. The preparation method at least comprises the steps of liquid preparation, encapsulation and sterilization, wherein the processes of liquid preparation and encapsulation are carried out under the protection of nitrogen. In a preparation process, a cysteine hydrochloride solution is prepared firstly, and then edaravone is added into the cysteine hydrochloride solution. By improving the preparation method of the edaravone injection and accurately controlling conditions, the preparation method provided by the invention not only does not need to change an original research prescription of the edaravone injection, but also can further improve the stability of the edaravone injection.
Owner:YANGZIJIANG PHARMA GROUP SHANGHAI HAINI PHARMA
Residential area extraction method
ActiveCN108592888AQuick extractionAccurate extractionPicture interpretationEarth surfaceResidential area
The invention discloses a residential area extraction method. The method comprises the following steps: collecting the Landsat 8 OLI sensor remote sensing image and the administrative boundary data ofa research area; preprocessing the remote sensing image; calculating the surface albedo of the preprocessed remote sensing image; extracting water bodies and shadows according to the surface albedo;extracting shadows from the obtained water and shadow map layer by using a single-band threshold technology to distinguish the water bodies and the shadows; performing closed operation filtering processing on the obtained water extraction result; calculating the normalized vegetation index of the preprocessed remote sensing image, determining a threshold, and cutting off the water body, shadow andvegetation maps extracted in above steps from the original boundary map layer of the research area to obtain a remaining map layer which is the residential area and road distribution map of the research area; and calculating the shape index of the residential area and the road distribution map, determining the threshold value of the shape index (I), and extracting roads and the residential area.The problems of large work intensity, low precision and low efficiency in existing residential area extraction are solved.
Owner:INST OF GEOCHEM CHINESE ACADEMY OF SCI
Preparation methods of parecoxib sodium and intermediate thereof
InactiveCN106674142AHigh puritySimple reactivityOrganic chemistryParecoxib sodiumPropionic anhydride
The invention discloses preparation methods of parecoxib sodium and intermediate thereof. The invention provides a preparation method of a parecoxib sodium intermediate I. The preparation method of the parecoxib sodium intermediate I comprises the following step: in the presence of a catalyst, performing condensation reaction on valdecoxib III and propionic anhydride to obtain the parecoxib sodium intermediate I, wherein the catalyst is one or more of benzenesulfonic acid, p-toluenesulfonic acid, methanesulfonic acid and sulfamic acid. The preparation method is simple in reaction and post-treating operation, high in yield and low in cost; the purity of the prepared intermediate product is high and can reach 99.80% or above, and the content of specific impurity valdecoxib reaches 0.02% or below and can meet the standard of an original researching manufacturer; therefore, the preparation method is suitable for industrial production. The purity of parecoxib sodium prepared from the parecoxib sodium intermediate I prepared by the preparation method provided by the invention can reach 99.80% or above and the content of the specific impurity valdecoxib reaches 0.01% or below and is higher than the standard of the original researching manufacturer.
Owner:SHANGHAI BOCIMED PHARMA CO LTD
Metronidazole tablet and preparation method thereof
InactiveCN108420800AHigh hardnessCrunchyOrganic active ingredientsAntimycoticsAdhesiveFiller Excipient
The invention discloses a metronidazole tablet. The metronidazole tablet comprises a plain tablet and a film coating, wherein the used plain tablet comprises the following raw materials in parts by weight: 50 to 60 percent of metronidazole, 20 to 50 percent of a filling agent, 2 to 20 percent of an adhesive and 0.1 to 0.4 percent of a lubricant; the used film coating comprises the following raw materials in percent by weight: 83 to 84 percent of hydroxypropyl methylcellulose and 16 to 17 percent of polyethylene glycol. Through the preparation method of the preparation, a wet granulation process is adopted, povidone K30 or corn starch serves as an adhesive, corn serves as starch, calcium hydrophosphate serves as the filling agent, magnesium stearate serves as the lubricant, and the hydroxypropyl methylcellulose serves as a coating material, so that the hardness, friability and in-vitro release of the preparation are improved, the metronidazole tablet has high hardness, the tablet is smooth and has high friability, the tolerance of the coating process is high, the prepared metronidazole tablet has in-vitro release consistent with that of metronidazole Spanish original research, the rapid release condition is met, the metronidazole tablet has equal curative effect, and the whole preparation method is simple to operate, controllable in quality and suitable for industrialized production.
Owner:南京双科医药开发有限公司
Calculation method for heterogeneous anisotropic hardened particle peripheral interface volume fractions
InactiveCN104732096AAccurate calculation of surrounding interface volume fractionAccurate calculationSpecial data processing applicationsNumber densityCalculation methods
The invention discloses a calculation method for heterogeneous anisotropic hardened particle peripheral interface volume fractions. The calculation method comprises the following steps that 1, the sizes of heterogeneous anisotropic particles are defined, and particle size distribution of the multi-particle-diameter heterogeneous anisotropic particles is calculated; 2, volume fractions of a base body are calculated; 3, the average volume and the average surface area of the heterogeneous anisotropic particles are calculated; 4, the number density of the heterogeneous anisotropic particles is calculated; 5, the heterogeneous anisotropic hardened particle peripheral interface volume fractions are calculated. The calculation method shakes off the restraint of the original research technology which can only be used for the simplest spherical particles, and the calculation method for interface volume fractions has higher universality and representativeness.
Owner:HOHAI UNIV
Hierarchical speech noise reduction recognition method and system under noise environment
The invention discloses a hierarchical speech noise reduction recognition method and system under a noise environment. The method comprises the following steps that a common text for communication bytelephone is set, and text entry is carried out; the set text is used for establishing a text database; according to the text, recording of pure speech and all kinds of noise is carried out; linear combination is carried out on the pure speech and all kinds of the noise to establish a speech database; endpoint detection is carried out on noisy speech to detect a front endpoint and rear endpoint ofeffective speech, and the effective speech is extracted; the effective speech is trained through a hierarchical method to obtain a speech enhancement deep neural network; the effective speech is subjected to speech enhancement, and then acoustic features of the effective speech are extracted; the acoustic features are used for training an acoustic model; the text is used for training a language model; the acoustic model and the language model are used for searching to obtain an optimum recognition result sequence. The hierarchical speech noise reduction recognition method and system under thenoise environment can improve the accuracy degree of recognition of original speech of a customer through noise reduction processing of the original speech of the customer.
Owner:广州九四智能科技有限公司
Ship-borne attitude and angle sensor detection method
ActiveCN102901518AGuaranteed reliabilityGuaranteed accuracyMeasurement devicesObservation dataTest platform
The invention discloses a ship-borne attitude and angle sensor detection method, wherein a detected instrument is placed on a detection device based on a ship-borne attitude and angle sensor detection device; according to requirements of detection flow and method, synchronous motion of the device and the detected instrument is realized through software of an upper computer of the detection device; and comparative analysis is performed on a testing parameter value and a detection instrument observation data value by using testing platform software to obtain a detection result and output a detection report. The ship-borne attitude and angle sensor detection method belongs to original research achievement and no related literatures are available.
Owner:SHANDONG UNIV OF SCI & TECH
Reshaping planting method for jujube trees
InactiveCN108575530AFacilitate mechanical farmingSimple materialGraftingCultivating equipmentsFruit treeMain branch
The invention relates to the technical field of fruit tree planting, in particular to a reshaping planting method for jujube trees. The technical purpose is to provide a jujube tree reshaping plantingmethod which reshapes a high crown tree shape to a small crown heart shape, makes jujube trees be conveniently managed, makes jujubes be conveniently picked, improves grafting survival rate during grafting. According to the specific scheme, in mid-April of the first year, all one-layer branch groups of an original tree are pruned, one layer has about three branches, and each branch has three lateral branches; grafting is performed on one-layer main branches, central tree trunk is reserved, and all sprouts on the central trunk are removed during growing period; in late May or mid-to-late July,root suckers are removed; the growing period is in the next year, and all sprouts on the central trunk are continuously removed; branches with a good variety are grafted on the one-layer main branch,possess conditions of bearing fruit after one-year growth, and are stretched during the period between mid-January and early May; in mid-to-late April of the third year, the central trunk is sawed, then the saw bite is immediately smeared with a coating agent, the saw bite is closely sealed and enclosed, and no gaps are reserved to help healing of the saw bite.
Owner:任鸿
Text classification method for research report text
InactiveCN110717044AImprove analysis efficiencyImprove text analysis capabilitiesNatural language data processingSpecial data processing applicationsText categorizationClassification methods
The invention relates to a text classification method for research report texts, which comprises the following steps: firstly, collecting a certain number of research reports, and marking collected research report paragraphs to form a sample; sending the labeled samples to a machine learning framework for training to obtain a comprehensive training model; and finally, performing content extractionand text noise reduction processing on an original research and report file to be identified, and finishing extraction and classification of research and report contents by the comprehensive trainingmodel. According to the method, the accuracy of extracting and classifying the research report paragraphs is effectively improved, and the text analysis capability of research reports is improved.
Owner:创新奇智(南京)科技有限公司
Method and system for visually modeling research big data on basis of expanding three-dimensional histogram
ActiveCN106815320AMeet the process requirementsWide applicabilityText processingResourcesGraphicsPretreatment method
The invention discloses a method and system for visually modeling research big data on the basis of an expanding three-dimensional histogram. The method comprises the following steps: initializing a three-dimensional visual model; pre-treating the research data in classification according to the specific data classification; reading the original research data, extracting and standardizing the expanding three-dimensional histogram data according to the requirement of the three-dimensional visual model and the result of the pretreatment in classification, and generating the expanding three-dimensional histogram data conforming to the standard formula of the three-dimensional visual model; and visually displaying the generated expanding three-dimensional histogram data according to a graphics method. According to the invention, on the basis of the expanding three-dimensional histogram, a uniform overall visual analysis result is formed, and the applicability is higher; the visual chart of the expanding three-dimensional histogram is linked with the original research data, so that the fidelity is high; and a corresponding effective data pretreatment method is adopted according to different data classifications, so that the method is more effective. The method and system disclosed by the invention can be widely applied to the field of big data treatment.
Owner:SOUTH CHINA NORMAL UNIVERSITY +1
Preparation method for intermediates of new medicine Lusutrombopag resisting to thrombopenia
ActiveCN106565625AAchieve synthesisEasy to repeatOrganic compound preparationCarboxylic acid esters preparationBrominePaper document
The invention discloses a preparation method for intermediates of a new medicine Lusutrombopag resisting to thrombopenia. According to the invention, column chromatography of each step is avoided through an effective method with regard to preparation for an intermediate I, and in addition, bromo-compounds are used for replacing chloro-compounds in the step of ring closure, thus the ring closure has a quantitative yield and is quite easy to operate. In addition, the second carbonyl group and bromine are introduced stepwise, thus the two steps achieve a yield of more than 80%, and are stable and easy to repeat. Compared with the yield of 25-30% of the last two steps of the original research document, the yield is greatly increased, and the preparation method is simple and convenient to operate, and easy to repeat. According to the invention, synthesis for an intermediate II is realized with a quite high yield (70-80%) and an extremely short route through two effective strategies with regard to the intermediate II.
Owner:杭州天泽生物医药有限公司
Atorvastatin calcium composition, preparation and preparation method thereof
ActiveCN108421045AImprove uniformityFully contactedMetabolism disorderInorganic non-active ingredientsMedical prescriptionSolvent
The invention relates to a stable atorvastatin calcium composition, a preparation and the preparation method thereof. The atorvastatin calcium preparation is prepared by micronizing active componentsand alkaline auxiliary materials in a prescription, suspending or dissolving into a mixed solvent of methanol and purified water and adopting a spray drying mode; compared with the original research product, the obtained preparation has higher stability, reduces adverse effect and improves the medicine compliance of patients; moreover, the dissolution uniformity is higher, and the bioequivalence test indicates that the product is bioequivalent to the original research product.
Owner:北京海晶生物医药科技有限公司
Preparation method of original fresh-keeping wild fungus
InactiveCN101336701AEasy to processProcessing, to achieve convenient storageFood preparationUltravioletWild mushroom
The invention discloses a method for preparing original flavor fresh-keeping wild mushroom. The technique steps are as follows: (1) the wild mushroom is cleaned for removing earth and foreign substance; (2) the mushroom is shaped, for example the mushroom or cut into block-shape or strip-shape and other needed shapes. (3) at normal temperature, the shaped wild mushroom is put into special perforated ladle and fried in oil pan of 90-250 DEG C for 3-15 seconds; (4) the wild mushroom is put out of oil pan and leached for 1 minute, and is processed by sterilization and preservative treatment; the sterilization treatment means that the wild mushroom is put under ultra-violet ray lamp for 20-40 minutes (or the wild mushroom is treated using related sterilization technique); (5) the wild mushroom is vacuumized and packed by vacuum bag and then the final product of the original flavor fresh-keeping wild mushroom is produced. The preparation method of the original flavor fresh-keeping wild mushroom according to the invention has the advantages that the fresh or freezing wild mushroom is treated and processed in such a manner that the wild mushroom is fried in heat oil, therefore the product can be conveniently stored, preserved, transported and processed, and can maintain freshness, shape and taste.
Owner:王宏
Public transport data based system and public transport data based method for calculating area popularity gathering index
ActiveCN103729499AAccurate measurementLow costSpecial data processing applicationsComputing systemsCost savings
The invention provides a public transport data based system and a public transport data based method for calculating an area popularity gathering index. The method includes the following steps: S1, collecting public transport data; S2, dividing an original area and establishing a buffering area according to the original area; S3, acquiring movement information of people going in and out of the original area from the public transport data to acquire an original popularity gathering index; S4, acquiring movement information of the people going in and out of the buffering area of the original area from the public transport data to acquire a popularity gathering index of the buffering area; S5, building a popularity guiding model according to an accumulated value of the original popularity gathering index and the popularity gathering index of the buffering area; S6, correcting the original popularity gathering index according to the popularity guiding model to acquire a final popularity gathering index. By the system and the method, the popularity gathering index of any specific area can be measured accurately without other measuring equipment; compared with existing measuring methods depending on video or infrared instruments, the method has the advantages of being more economical in cost, simple, convenient and quick.
Owner:深圳市北斗智能科技有限公司
Preparation method of irbesartan capsule
ActiveCN107028912AHigh dissolution rateImprove stabilityOrganic active ingredientsPharmaceutical non-active ingredientsGeneric drugMedicine
The invention discloses a preparation method of an irbesartan capsule and application in the evaluation of generic drug consistency. After Irbesartan is mixed with various auxiliary materials to prepare a soft material, granulation is performed through an extruding granulation method, granules are evenly mixed with a lubricant after drying, and the capsule is filled. The irbesartan capsule produced by adopting the preparation process is consistent to an original research product (product name: irbesartan tablets; trade name: Avapro; specification: 0.15 g; production manufacturer: Sanofi Winthrop Industrie) on the aspect of multiple in-vitro dissolution curves, related substances have no obvious change in the test acceleration and long-term test stability investigation process and are biologically equivalent to the original research product.
Owner:珠海润都制药股份有限公司
Norfloxacin composition
InactiveCN107661305APromote dissolutionAddressing Poor Dissolution ProblemsAntibacterial agentsOrganic active ingredientsCross-linkFiller Excipient
The invention relates to a norfloxacin composition and belongs to the technical field of pharmacy. According to the technical scheme provided by the invention, the norfloxacin composition is preparedfrom norfloxacin, lactose, cross-linked sodium carboxymethyl cellulose and other pharmaceutically acceptable auxiliary materials. The pharmaceutically acceptable auxiliary materials comprise a fillingagent and a lubricant and the granularity of the norfloxacin is distributed in a range that D90 is greater than or equal to 200mu m and less than or equal to 300mu m. The invention provides the stable norfloxacin composition with a dissolution behavior which is the same as that of an original research.
Owner:迪沙药业集团(天津)药物研究有限公司 +1
Azacitidine freeze-drying powder needle for injection and method for preparing azacitidine freeze-drying powder needle
InactiveCN108295034AExcellent total impurity levelReduce genotoxic potentialOrganic active ingredientsPowder deliveryOrganic solventFreeze-drying
The invention discloses an azacitidine freeze-drying powder needle for injection, the azacitidine freeze-drying powder needle comprises the raw materials, by weight, of 2-8 parts of azacitidine, 2-8 parts of mannitol and 150-400 parts of organic solvent. The invention further provides a method for preparing the azacitidine freeze-drying powder needle for injection. According to the azacitidine freeze-drying powder needle for injection and the method for preparing the azacitidine freeze-drying powder needle, by changing the technical key points of the product solvent formula, the solution preparation temperature, the charging sequence, the freeze-drying process and the like, the impurity level of the product can be effectively controlled, and the freeze-drying preparation with the stabilitysuperior to that of the foreign original research products can be produced.
Owner:KINDOS PHARM CO LTD +1
Production method of bamboo shoots
ActiveCN104522149AIncrease the sugar contentIncrease sweetnessFruits/vegetable preservation by heatingFlavorFermentation
The invention discloses a production method of bamboo shoots and belongs to the technical field of food processing. The production method comprises the following process steps: soaking; pre-cooking; cooling; peeling and shaping; cleaning and canning; sterilizing; cooling; carrying out secondary sterilization; cooling; inspecting; and boxing and warehousing. The production method disclosed by the invention has the advantages that a product finally obtained stores the original fresh and fragrant flavor of the fresh bamboo shoots to the greatest extent; and compared with the boiled bamboo shoots produced by the traditional fermentation process, the problems that the traditional boiled bamboo shoots are sour and the flavor is bad are solved.
Owner:FUYANG HANGFU CANNED FOOD
Method for controlling oxygen solubility of original beer in cold-chain logistics process
ActiveCN106698308AFree from pollutionReasonable structural designLiquid dispensingCold chainOxygen solubility
The invention relates to the technical field of oxygen solubility control, particularly to a method for controlling the oxygen solubility of original beer in cold-chain logistics process. Fully-enclosed bear injection is achieved through controlling the process from ex-factory transport of the original beer to injection of the original beer into bear terminals; the oxygen content of the original beer is monitored through arranging an oxygen solubility detection feedback system; the oxygen solubility is reduced in the form of injecting carbon dioxide when the oxygen solubility is out of limit through arranging an oxygen solubility regulating system; if detecting beer deterioration, disinfectants are injected into a pipeline through connecting a cleaning pipeline so as to ensure the oxygen solubility of the original beer in the cold-chain logistics process. The method provided by the invention is rational in design and original in conception. A full-sealed bear injection docking device is designed to ensure that the internal and external environments of the device are in the sealed state all the time and exempted from pollution by outside environment. In the device, the oxygen concentration in the pipeline and a target container can be adjusted automatically through an oxygen solubility control system so as to meet the requirements of safety, refreshment and bear injection.
Owner:SHANDONG HIFRE TECH
Preparation method and composition of cefradine with original research quality
ActiveCN105713011ASimple manufacturing methodMild process reaction conditionsAntibacterial agentsOrganic active ingredientsCefradineSolvent
The invention discloses a preparation method of cefradine with an original research quality on the basis of KR840002043 (B1) and US4235900 (A). The preparation method comprises steps as follows: (1) dihydrophenylglycine chloride hydrochloride is added to a solvent, the mixture is cooled, protected 7-ADCA is added to the mixture, and the mixture is subjected to a condensation reaction after being mixed; (2) water and hydrochloric acid are added after the reaction ends, the mixture is subjected to a hydrolysis reaction, an organic phase layer is left to stand for use, a water layer is subjected to vacuum distillation, and non-distillate is retained; (3) the non-distillate is crystallized and filtered, filtrate is left to stand for use, a filter cake is washed and dried, and cefradine is obtained; (4) the organic phase layer and the filtrate are combined, and cefradine is recycled and extracted. The invention further discloses composition of cefradine with the original research quality. The prepared cefradine and the cefradine composition have the original research quality, the preparation method is simple, the reaction conditions of the whole procedure are relatively mild, the cost of raw materials is low, little pollution is caused, and the prepared cefradine composition has stable and high quality.
Owner:广东金城金素制药有限公司 +1
Cognition-based original resource and detected hole resource joint allocation method
ActiveCN108024370AAchieve sharingImprove performancePower managementTransmission monitoringLimited resourcesFrequency spectrum
In order to solve the problem that through adoption of an existing allocation method, limited resources cannot be sufficiently utilized and high system throughput and energy efficiency cannot be acquired, the invention discloses a cognition-based original resource and detected hole resource joint allocation method and belongs to the technical field of information and communication. The method comprises the steps that the user minimum data transmission rate R<min>, a user available power upper limit P<max><T>, a spectrum detection threshold I1 and a sub-channel interference preset thresholdI2 are set; a BS / AP (Base Station / Access point) node in a multi-attribute heterogeneous system allocates original sub-channels to each user and detects spectrum hole sub-channels in the multi-attribute heterogeneous system through utilization of the spectrum detection threshold I1and the sub-channel interference preset threshold I2, and the BS / AP node allocates the detected spectrum hole sub-channels to each user; and when allocation is carried out, the fact that R<m> is greater than or equal to the R<min> and P<m> is smaller than or equal to P<max><T> is taken as a limitation condition, and moreover, through utilization of a Lagrange duality method, an optimum user original sub-channel allocation result and an optimum spectrum hole sub-channel allocation result are acquired,wherein the R<m> indicates a data transmission total rate of a user m, and the P<m> indicates the total power consumed by the user m.
Owner:HARBIN INST OF TECH
Method for determining dissolution curve of lanthanum carbonate chewable tablets
InactiveCN110108832AEfficiently distinguish the effects of in vitro releaseQuality assuranceComponent separationLanthanum carbonate Chewable TabletGeneric drug
The invention relates to the field of analytical chemistry, in particular to a method for determining a dissolution curve of lanthanum carbonate chewable tablets. An oar method is adopted, wherein a dissolution medium is 0.25 N hydrochloric acid solution, and the rotating speed is 50-75 revolutions per minute. The method for determining the dissolution curve of the lanthanum carbonate chewable tablets has the characteristics of science, durability, reproducibility and the like, the influence of different prescriptions and process variables on the in vitro release of the lanthanum carbonate chewable tablets can be effectively distinguished, the method for determining the dissolution curve of the lanthanum carbonate chewable tablets can be used for quality consistency evaluation of generic drugs and original research drugs, guarantee can be provided for consistency of quality between batches of drugs, the quality of the drugs is further ensured, and consistency of quality and curative effect is achieved.
Owner:BEIJING YUEKANGKECHUANG PHARM TECH CO LTD
Traceability risk assessment method for aflatoxin in oil crops
The invention discloses a traceability risk assessment method for aflatoxin in oil crops in the technical field of food safety. The method comprises the following main steps of: S1: carrying out original research on grain and oil crops; S2: carrying out sample pretreatment; S3: carrying out sample detection and data acquisition; S4: carrying out data analysis and result output; S5: establishing aflatoxin exposure assessment indicators; S6: establishing an aflatoxin exposure assessment model; and S7: controlling the product storage environment and storage time of plant edible oil. According tothe method, a liquid quality-mass spectrometry technique is used to determine the content of aflatoxin; the sample pretreatment process is simplified, so that the detection efficiency is improved; thecontent of aflatoxin daily ingested by human body is fitted to establish the aflatoxin exposure assessment model; and the content of aflatoxin is controlled from the planting, processing and productstorage links of oil crops, thereby reducing the daily ingestion of the human body and improving the safety of grain and oil crops.
Owner:CHONGQING ACAD OF AGRI SCI
Azacitidine lyophilized powder for injection and preparation method thereof
ActiveCN109820827AExcellent levelReduce spawn ratePowder deliveryOrganic active ingredientsMANNITOL/SORBITOLFreeze-drying
The invention provides azacitidine lyophilized powder for injection. The azacitidine lyophilized powder is prepared from, by weight, 2-8 parts of azacitidine, 2-8 parts of mannitol, 100-300 parts of acetonitrile and 684-896 parts of water. The invention further provides a preparation method of the azacitidine lyophilized powder for injection. The preparation method comprises the steps that part ofthe water for injection is added into a liquid preparation tank; 100-300 parts by weight of acetonitrile is added, and stirring is conducted until the mixture is clear; 2-8 parts by weight of mannitol is added, stirring is conducted until the mixture is completely dissolved, and the temperature is lowered to be 0-4 DEG C; 2-8 parts by weight of a pre-micronized raw azacitidine material is weighed, washed with part of the remaining water for injection and then added into the liquid preparation tank, intensive stirring is conducted until the mixture is dissolved, and the water for injection isadded to reach the constant volume of 1000 parts; after sterile filtration, filling and freeze-drying, the preparation product is obtained. The particle size of the product and the total impurity level of the product can be effectively controlled, the stripping curve and other bioequivalence indexes of the product are equivalent to those of an original research product, and the total impurity level is lower than that of the original research product.
Owner:KINDOS PHARM CO LTD +1
Tree growth history observation method
PendingCN107945171AControl thicknessControl precisionImage enhancementImage analysisWoodworking machineComputer software
The invention relates to a tree growth history observation method which is suitable for forestry scientific research workers and can provide forestry scientific research workers with accurate data ofthe complete growth process of trees and forest stands. The method comprises the three steps of standard wood selection, digital slice image acquisition and growth history data extraction. The methodhas the advantages that an improved woodworking machine tool is added with a longitudinal slide rail and can well control the cutting thickness and precision of wood; full-tree tree growth history data of the millimeter level can be acquired; the growth process of trees can be grasped in more detail; each section is stored as an image; the information of various measurement factors of trees can beextracted through computer software; and image data can be repeatedly studied, but an original tree can only be studied once, and cannot be repeatedly studied.
Owner:BEIHUA UNIV
A kind of preparation method and composition of original developed quality cephradine
ActiveCN105713011BSimple manufacturing methodMild process reaction conditionsAntibacterial agentsOrganic active ingredientsCefradineSolvent
Owner:广东金城金素制药有限公司 +1
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com