120 results about "Milk Thistle" patented technology

The invention relates to a general-purpose composite Chinese herbal medicine immune enhancer for freshwater cultured fish, which is made of raw materials with the following weight ratios, based on the amount added per ton of feed: rhubarb 800-2000g; Sanqi 350-1000g; water Silybum 1200-2500g; Cassia 600-800g; Astragalus 600-2000g; Scutellaria baicalensis 500-900g; 500-1500g; Garlic 1000-2000g. After many tests in the laboratory, it has been proved that the general-purpose compound Chinese herbal medicine immune enhancer for freshwater aquaculture fish can improve the survival rate of a variety of freshwater aquaculture fish in the process of attacking viruses; The long-term breeding experiment of farmed fish feed proves that the general-purpose compound Chinese herbal medicine immune enhancer for freshwater farmed fish can effectively reduce the incidence of a variety of high-density farmed freshwater fish and improve the survival of the breed; the additive is safe, efficient, and has no side effects for long-term use. The breeding objects have strong vitality, rapid growth, bright body color, high feed conversion rate, and good breeding benefits.

A melanin preparation as an immunostimulatory agent from at least one of the following botanicals: Echinacea, American ginseng, black walnut, green tea, Parthenium integrifolium, Korean ginseng, alfalfa sprouts, ginger, goldenseal, red clover, dandelion, black cohosh, licorice, chamomile, milk thistle, alfalfa, horsetail, astragalus, gotu kola, feverfew, valerian, hawthorn, rosemary, saw palmetto, ephedra, pau d'arco, ginkgo, garlic, St. John's wort, Agaricus bisporus (common mushroom), Agaricus bisporus brown strain (portabella mushroom), Lentinus edodes (shiitake mushroom) or Boletus edulis (porcini mushroom). Also disclosed is methods of treating a subject requiring immune mediation comprising administering to said subject a therapeutically effective amount of a melanin preparation from any one of the following botanicals: Echinacea, American ginseng, black walnut, green tea, Parthenium integrifolium, Korean ginseng, alfalfa sprouts, ginger, goldenseal, red clover, dandelion, black cohosh, licorice, chamomile, milk thistle, alfalfa, horsetail, astragalus, gotu kola, feverfew, valerian, hawthorn, rosemary, saw palmetto, ephedra, pau d'arco, ginkgo, garlic, St. John's wort, Agaricus bisporus (common mushroom), Agaricus bisporus brown strain (portabella mushroom), Lentinus edodes (shiitake mushroom), Boletus edulis (porcini mushroom).

A dietary nutritional supplement is designed specifically to address the needs of moderate to heavy alcohol product consumers. The nutritional supplement contains effective amounts of essential components vitamin B2, vitamin B6, vitamin B12 (Cobalamin), vitamin B3 (Niacin), vitamin B1 (Thiamin), Calcium, magnesium, vitamin A, vitamin C (ascorbic acid), folic acid, L-cysteine, L-methionine, Milk Thistle, selenium, dandelion, and Molybdenum.

The invention provides application of dehydrogenated silibinin diether in the preparation of medicaments for preventing and treating leukemia and relates to medical application of lignin flavone silibinin to the prevention and treatment of chronic myeloid leukemia. Particularly, the invention relates to application of dehydrogenated silibinin diether, of which the seventh bit and the twentieth bit are substituted by 1-butylene, or pharmaceutically acceptable salts thereof in the preparation of medicaments for preventing and treating chronic myeloid leukemia. Natural products of the silibinin are treated by simple steps to synthesize the compound. The pharmacological tests prove that the compound can potently inhibit the in-vitro proliferation of human chronic myeloid leukemia cell strains(K562) and adriamycin drug-resistant strains (K562 / ADR), and the IC50 values are 11.9+ / -1.6 micromoles and 15.9+ / -1.2 micromoles respectively.

A pharmaceutical preparation comprising progestin, estrogen and a multivitamin agent. The progestin may be between 0 and 0.50 mg Desogesterel and the estrogen may be between 0 and 0.2 mg Ethinyl Estradiol. The multivitamin agent may be any combination of alpha carotene, beta carotene, biotin, bioflavonoid, calcium, chasteberry fruit, chromium, copper, coenzyme Q10, cryptoxanthin, dong quai root, folic acid, ginkgo biloba, garlic, grape seed extract, green tea extract, hesperedin, iodine, iron, lutein, malic acid, manganese, magnesium, milk thistle, molybdenum, niacin, panthothenic acid, potassium, pyridoxine HCL, quercetin, riboflavin, rutan, selenium, thiamine, vitamin A, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, vitamin K, zinc, zoexanthin and any combination thereof.

A method for creating a coffee drink that having the addition of a nutraceutical additive composition of milk thistle; chromium picolinate, and carnitine. Milk thistle is present from about 50 to 99.7 parts by weight of the total composition, and preferably 50 to 60 parts by weight. Chromium picolinate is present from about 0.01 to 0.23 parts by weight of the composition and preferably from 0.01 to 0.1 parts by weight. Carnitine is present from about 0 to 50 parts by weight of the total composition, and preferably 40 to 50 parts by weight. The coffee drink can be created by an admixture of the composition with ground beans, sprayed and / or coated on the bean prior to grinding, or added to a brewed much the same as one would add sugar or other known flavor additives. The instant composition does not subtract from the flavor and improves human physiology by assisting in weight loss, body cleansing, weight loss, fat burning, and sugar regulation.

A natural adaptogenic tea is prepared from adaptogens to counter adverse physical, chemical, or biological stressors and to promote t-cell activity and k-cell activity. Also, the composition is high in antioxidants and discourages free radicals. Moreover, the composition improves liver performance, resulting in improved toxin removal and improved nutrient absorption. In addition to these benefits, the composition improves capillary dilation, thereby providing better oxygenation to the brain. The tea is prepared from adaptogens including rhodiola, ashwagandha, schizandra berry, eleuthero and astralagus. Also, the tea includes damiana leaf, passion flower, milk thistle, white willow bark, goji berry, mangosteen, pomegranate, green tea, and sarsaparilla.

The invention belongs to the field of pharmaceutical preparation, in particular a method for preparing cyclodextrin inclusion compound of silybum mariamum extract and medicinal formulation thereof, wherein a dissolvent method is employed to prepare beta-cyclodextrin or its derivative inclusion compound from the Silybum marianum extract, the organic solvent is removed through depression. The advantages of the method include simple process for manufacturing, low cost of manufacture, and fitting for mass production.

This invention provides therapeutic compositions and combinations for the protection, treatment and repair of liver tissue. The invention relates to novel compositions and combinations comprising two or more compounds selected from the group consisting of S-adenosylmethionine, L-ergothioneine, and a substance selected from the group consisting of constituents of Milk thistle (Silybum marianum), silymarin and active components of silymarin, whether naturally, synthetically, or semi-synthetically derived, and to methods of preventing and treating liver disease and of repairing damaged liver tissue. The invention also provides a method of administering these compositions and combinations to humans or animals in need thereof.

The invention relates to biodiesel prepared by non-edible vegetable oil and a method thereof, which belong to the biodiesel field. By-product milk thistle oil produced during the production process of Silibinin serves as a raw material for preparing the biodiesel. The biodiesel is obtained by transesterification of the milk thistle oil and methyl alcohol under the condition of a catalyst. Gas chromatography-mass spectrometry analysis results show that main components of the biodiesel prepared by the milk thistle oil serving as the raw material are methyl oleate and methyl linoleate. The biodiesel is high in cetane number, excellent in performance and capable of meeting China current biodiesel standard. In addition, the biodiesel is simple in process, mild in reaction condition, low in cost and capable of achieving large-scale production.

A healthful sea salt mixture composed of at least one whole sea salt, at least one organic whole sea vegetable, at least one whole raw sesame seed type, optional chia seeds and optional milk thistle. The at least one whole sea salt includes but is not limited to Celtic sea salt, pink Himalayan sea salt, and Bolivian rose sea salt. The at least one organic whole sea vegetable includes but is not limited to alaria, dulse, kelp, layer, and sea lettuce. The at least one whole raw sesame seed type includes various families of sesame seeds. The present invention provides a whole food source that has numerous minerals and nutrients. The present invention also serves as an iodine supplement for those with a thyroid-related condition. Furthermore, the present invention provides vitamin E, which aids in iodine absorption. The range of nutrients provided includes potassium, calcium, sodium, vitamins, and others.

The invention belongs to the field of foods and particularly relates to a jelly capable of clearing bowels, expelling toxin, maintaining beauty and keeping young and a preparation method of the jelly. The jelly is prepared from the following components in parts by weight: 10-20 parts of fructo-oligose, 5-10 parts of xylooligosaccharide, 5-10 parts of resistant dextrin, 1-5 parts of barley leaf powder, 4-8 parts of dendrobium powder, 8-14 parts of chia seeds, 1-5 parts of L-carnitine, 5-10 parts of tuna polypeptide, 10-20 parts of konjaku flour, 3-7 parts of turmeric, 8-16 parts of radix pueraiae powder, 2-6 parts of milk thistle powder, 20-30 parts of a thickener, 1-3 parts of microencapsulated citric acid and 100-120 parts of water. The jelly capable of clearing bowels, expelling toxin, maintaining beauty and keeping young has the effects of expelling toxin, relaxing the bowels, reducing fat and nourishing the skin, has relatively good elasticity, transparency and stability, and is good in taste and convenient to carry and eat.

The invention discloses a traditional Chinese medicine extractive composition and a preparation method thereof, wherein the extractive composition is prepared from the following components: by weight, 42-62 parts of hedera helix extractive, 5-10 parts of Marian thistle extractive, 3-5 parts of olive leaf extractive, 6-12 parts of fennel extractive, 10-15 parts of liquorice extractive, 10-15 parts of radix ophiopogonis extractive, 10-15 parts of dried tangerine peel extractive, and 8-10 parts of radix polygonati officinalis. By a special technology, the hedera helix extractive, Marian thistle extractive, olive leaf extractive, fennel extractive, liquorice extractive, radix ophiopogonis extractive, dried tangerine peel extractive and radix polygonati officinalis of higher purities are obtained and combined by an optimal proportion. The composition has a good curative effect on cough; it is safe and nontoxic with remarkable curative effect, and without generating resistance to drugs; it clinical effective rate is up to 97%, and its cure rate is up to 92%.

Disclosed is a safe substance which can inhibit the activity of aromatase (an enzyme capable of converting androgen into estrogen) to thereby effectively treat and / or prevent a sex hormone-dependent disease such as breast cancer occurring in a female person after menopause, as well as a climacteric disorder in a male person and metabolic syndrome caused by the accumulation of a visceral fat. Specifically disclosed is a therapeutic and / or prophylactic agent for a sex hormone-dependent disease, which is characterized by comprising at least one herbal extract selected from the group consisting of “Kokeiten” (golden root), prunella spike, sweet hydrangea leaf, milk thistle, a jasmine tea, “Bokusoku” (a bark of Quercus acutissima or a closely related plant thereof), “Tencha” (sweet tea), “Karensou” (Eclipta prostrata), “Youbaihi” (a bark of Myrica rubra Sie b. et Zucc.), French maritime pine, betel palm, asparagus, “Rouro” (a root of Rhaponticum unifloru m DC. or Echinops latifolius Tausch), “Ryoukyou” (a rhizome of Alpinia officinarum Hance), rooibos tea, rhubarb, pu-erh tea, green tea, “Ougon” (a root of Scutellaria baicalensis Georgi), St. John's wort (Hypericum perforatum L.), licorice, “Senrikou” (Senecio scandens Buch.-Ham.), wintergreen, “Kashi” (a matured fruit of Terminalia chebula Retz.), “Yagotou” (a bark of Mallotus japonicus), polygnum root, barrenwort (Epimedium Herb), guarana, “Ouhi” (a bark of Prunus jamasakura Sieb. ex. Koidz. or a closely related plant thereof), Argy's wormwood, sticky rehmannia, Japanese cornel, Asiasarum root, cinnamon, peony root, pine needle and amla fruit.

A pharmaceutical composition and method for modifying levels of cholesterol is described. Implementations of a pharmaceutical composition may comprise milk thistle and one of niacin, policosanol, and both niacin and policosanol. Implementations of a pharmaceutical composition may be administered using a method for reducing total cholesterol, LDL cholesterol, and triglycerides and increasing HDL cholesterol levels in a human or animal. The method may include the step of administering a pharmaceutically effective amount of a pharmaceutical composition that includes milk thistle and one of niacin, policosanol, and both niacin and policosanol to a human or animal.

The invention discloses a composition for regulating blood lipid and blood pressure and a preparation method thereof. The composition is prepared from, by weight, 10-15 parts of flos lonicerae extract chlorogenic acid, 15-20 parts of nostoc fermentation powder, 10-15 parts of cortex cinnamomi stems and bark, 3-6 parts of celery seed essence, 10-15 parts of milk thistle, 10-15 parts of corn stigma, 3-10 parts of cranberries, 3-10 parts of folium ginkgo, 10-15 parts of olive leaves and 4-6 parts of propolis. The composition is based on the principle of regulating blood lipid and blood pressure of traditional Chinese medicine, the selected traditional Chinese medical materials have the effects of lowering blood pressure, blood lipid and blood sugar and improving immunity, the effect is good, no side effect is caused after the composition is eaten for a long time, and the composition can be pressed into tablets or encapsulated into capsules for preservation and is convenient to eat and carry.

The invention discloses a method for extracting holy thistle total flavonoids from holy thistle stalks and relates to an extraction method of holy thistle total flavonoids, which achieves the comprehensive utilization of holy thistle stalks, increases the comprehensive utilization efficiency of holy thistle resources, reduces the investment recovery period and increases the supply of holy thistle total flavonoids. The pulverized holy thistle stalks are extracted with ethanol to get an extraction liquid, then the extraction liquid is concentrated and precipitated with alcohols, and the alcohol precipitates are washed and dissolved in ethanol, followed by decolorization and concentration. The invention achieves the purpose of holy thistle stalk reuse as a cyclic economy project, so as to stimulate the development of holy thistle farming, increase the added value of holy thistle stalks, increase the incomes of farmers and brings obvious economic and social benefits. The weight percentage concentration of the holy thistle total flavonoids disclosed by the invention, is 60% to 70%, and the yield is 0.1% to 0.2% of holy thistle stalks.

The invention provides a preparation method of silymarin. The preparation method comprises the steps of: firstly preparing composite microorganism fermenting agent freeze-dried powder of Trichoderma reesei CICC 13052 and Trichoderma koningii CICC 40144, activating with 2% glucose solution, inoculating the activated composite microorganism fermenting agent freeze-dried powder to silybum mariamum deoiled seed cake powder with moisture content of 40-45% and sucrose content of 4.2-4.8%, carrying out heat-insulation fermentation at 25-28 DEG C for 60h, drying by hot air, extracting at 15-20 DEG C and vacuum degree of -0.1MPa for 10h to obtain yellow powdered substance, adding methanol for dissolving, filtering, and vacuum-drying insoluble substance to obtain silymarin.

The invention discloses a warm chloasma-removing antiallergenic essence which is prepared from the following raw materials in parts by weight: 1-2 parts of sodium hyaluronate, 0.4-0.6 part of sodium polyacrylate, 0.5-0.7 part of isothiazolone, 2-3 parts of beeswax, 2-3 parts of evening primrose oil, 20-25 parts of milk thistle, 1-2 parts of curcumin, 33-37 parts of dendrobe, 10-13 parts of protea cynaroides, 16-20 parts of cranberry, 40-50 parts of waste hair, 3-4 parts of cupu oil, 13-15 parts of conch powder, 0.2-0.4 part of ceramide, 2-3 parts of butanediol, 2-3 parts of aloe gel, 1-2 parts of dipotassium glycyrrhizinate, 2-3 parts of octadecanol, 8-10 parts of freeze-dried pomegranate husk powder, 7-9 parts of freeze-dried pomegranate seed powder, 4-5 parts of horse oil, 1-2 parts of inulin and 65-76 parts of water. The essence prepared from natural materials has a good effect of inhibiting tyrosinase, can inhibit melanin, remove chloasma and improve skin from inside to outside, and is safe, reliable and convenient for application and popularization.

The invention discloses a traditional Chinese medicinal composition for protecting the liver and kidney of a chicken. The traditional Chinese medicinal composition is prepared through using the following raw materials, by weight, 10-20 parts of Poria cocos, 12-18 parts of Radix Astragali, 10-15 parts of Salvia miltiorrhiza, 30-40 parts of Semen Plantaginis, 15-25 parts of Twinleaf Zzornia, 10-15 parts of Chinese angelica, 18-24 parts of Fructus Gardeniae, 5-10 parts of Amur Corktree Bark, 10-15 parts of Chinese magnoliavine, 8-12 parts of Rhizoma Alismatis, 11-16 parts of radix bupleuri, 15-20 parts of pueraria flower, 10-15 parts of broadleaf holly leaf, 16-22 parts of Glutinosae Rice Root, 10-15 parts of Milk Thistle, 5-10 parts of Acorus gramineus, 8-12 parts of Geranium wilfordii Maxim. and 5-10 parts of Caulis Sinomenii. The traditional Chinese medicinal composition has multiple efficacies of heat clearing, detoxifying, blood circulation invigorating, swelling eliminating, liver coursing, gall benefiting, urination promoting, kidney protecting and the like after scientific and reasonable compatibility, has extensive effects, has good effects on liver and kidney damages caused by all reasons, and has the advantages of fast curative effect, high cure rate, no toxic side effects, no medicinal residue, and promotion of the fast growth of chickens.

The invention discloses a freckle-removing moisturizing lotion, made with the following materials according to parts by weight: 3-4 parts of tartaric acid, 3-4 parts of stearamidopropyl dimethylamine, 2-3 parts of squalane, 0.2-0.3 part of tea tree essential oil, 2-3 parts of polyhydroxystearate, 4-5 parts of propylene glycol, 3-4 parts of glycerol, 0.1-0.2 part of eucalyptus leaf oil, 20-25 parts of milk thistle, 33-37 parts of dendrobium flower, 10-13 parts of peepul flower, 16-20 parts of cranberry, 40-50 parts of waste hair, 4-5 parts of isooctyl palmitate, 3-4 parts of shea nut butter, 13-15 parts of shell powder, 1-2 parts of polyethylene glycol (n) lanolin ether, 17-20 parts of seaweed powder, 0.3-0.4 part of vitamin C, 0.2-0.4 part of chamomile essential oil, 5-6 parts of ethylene glycol monostearate, 1-2 parts of synanthrin, and 65-75 parts of water; the freckle-removing moisturizing lotion is secure and free of toxic and side effects, is friendly to skin, may be used often to whiten and soften skin, provides fine skin and thoroughly removes facial freckles, chloasma and the like.

The invention discloses traditional Chinese medicine composition for treating liver cirrhosis. The composition comprises raw materials in parts by weight as follows: 10-15 parts of pilose asiabell roots, 16-22 parts of bighead atractylodes rhizome, 12-18 parts of curcuma aromatica, 10-15 parts of artemisia capillaris, 8-14 parts of Chinese lobelia herbs, 5-10 parts of tamariskoid spikemoss herbs, 10-15 parts of rhizoma atractylodis, 6-12 parts of rush pith, 9-16 parts of radix bupleuri, 10-15 parts of common burreed rhizome, 5-10 parts of curcuma zedoary, 15-20 parts of Danshen roots, 17-23 parts of common peony roots, 10-15 parts of gynura formosana, 12-18 parts of herba lycopi, 7-13 parts of fructus aurantii, 5-10 parts of coix seeds, 10-15 parts of angelica keiskei, 10-15 parts of astragalus membranaceus, 5-10 parts of rhizoma corydalis, 12-18 parts of turtle shells, 16-22 parts of pangolin scales, 10-15 parts of nutmeg, 5-10 parts of agilawood, 15-20 parts of nutgrass galingale rhizome, 10-15 parts of green tangerine peel and 5-10 parts of milk thistle. The traditional Chinese medicine composition has functions of liver and kidney nourishing, qi circulation promoting, diuresis inducing, blood stasis dispersing, pain relieving, liver soothing, qi flowing regulating, spleen strengthening and food retention removing and is good in liver cirrhosis treatment effect, definite and fast in efficacy, short in treatment course, high in cure rate, free from toxic and side effects and worthy of popularization and application.

A quality control method for the medicine 'Dangfeiliganning' includes such areas as testing its characters, examining its appearance, thin-layer chromatographic determination of silibinin, oleanolic acid and gentiopicroside, and measuring the contents of silibinin and gentiopicroside.

The invention discloses a fermented Chinese herbal medicine additive for increasing yield of oyster seedlings. The fermented Chinese herbal medicine additive is prepared from the following raw materials (by weight): 6-12% of gynostemma pentaphylla, 3-5% of coptis, 4-8% of Hizikia fusiforme, 4-8% of milk thistle, 5-10% of sweet wormwood, 6-12% of magnolia cortex, 10-15% of purslane, 4-8% of dandelion, 6-15% of epimeddium, 8-15% of isatis root, 5-10% of cordate houttuynia, 5-10% of perilla leaf and 4-8% of plantago. The invention also discloses a preparation and application method of the fermented Chinese herbal medicine additive for increasing yield of oyster seedlings. The Chinese herbal medicinal raw material sources are wide, the cost is low, and the production processing technology is simple. By ultrasonic-assisted extraction and then by aerobic fermentation and anaerobic fermentation, functional components and beneficial microbial components of the Chinese herbal medicine are enhanced. The product has effects of improving water for growing oyster seedlings, effectively inhibiting outbreak of disease microbes, enhancing immunity and disease resistance of oyster seedlings and raising survival rate of seedlings. The product is an ideal, green, environment-friendly, safe and novel Chinese herbal medicine additive.

The invention discloses a medicinal composition for treating physiological disorder, and a preparation method thereof. The medicinal composition is prepared from schizonepeta spike, white batryticated silkworm, Smilax scobinicaulis C.H. Wright, Ligusticum wallichii, Milk Thistle, 50-80mg of Radix Peucedani, Incised Notopterygium, Eriocaulon buergerianum, cranberry extract, celery seed essence, grape seed essence, Oenothera biennis oil, Lepidium meyenii powder, sweet tea polyphenol, sweet tea flavones, spirulina, ladostigil tartrate, ammonium 5-methylisoxazole-3-carboxylate, hexadecyl palmitate and isopropyl myristate. The preparation method is simple, and the obtained medicinal composition can be used in an oral manner, an inhalation manner, a parenteral manner, a local manner or a suppository manner to treat inflammations and physiological disorder, and also has the advantages of good effects and small side effects.

An antioxidant-promoting composition that increases antioxidant defense potential in a subject is disclosed. The composition contains Bacopa monnieri extract comprising a Bacopa monnieri active ingredient; a Silybum marianum (milk thistle) extract comprising a Silybum marianum active ingredient; a Withania somnifera (ashwagandha) extract comprising a Withania somnifera active ingredient; a Camellia sinensis (green tea) extract comprising a Camellia sinensis active ingredient; a Curcuma longa (turmeric) extract comprising at least one Curcuma longa active ingredient, and optionally a Centella asiatica (Gotu kola) extract; a Ginko biloba extract; an Aloe vera extract; and N-acetyl cysteine. The process for quantifying Nrf2 transcription factor activating potential of the botanical extracts comprising the botanical active ingredients is described.