The invention relates to an injection for treating
livestock bacterial dysentery and a preparing method thereof. The injection is prepared by (1) adding 100-400 kg / L of
sodium salicylate into a part of water for injection, adding 10-150 kg / L of mequindox, and stirring for 10-20 min until the liquid is clear; (2) weighing a part of water for injection, adding 5-110 kg / L of
apramycin sulfate, 1-20 kg / L of
atropine sulfate and 1-20 kg / L of
chlorphenamine in order, and stirring for
dissolution; and (3) combining the solution prepared in the step (1) and the solution prepared in the step (2), adding the water for injection to a labeled volume, stirring uniformly, and maintaining for 15-20 min, then after the
medicine solution is clear, the compound
apramycin sulfate injection is obtained. The compound preparation comprising the
apramycin sulfate and the mequindox has obvious treating effects for swine
bacterial dysentery and can effectively relieve body stress responses of the
livestock with diseases. Experiments prove that: combination of the apramycin sulfate, the mequindox and the
atropine sulfate can obviously enhance curative effects; the injection is widely used in clinical; and the injection can be widely used for treatment of
bacterial dysentery of swine, cattle, sheep, and other
livestock, and can increase the
survival rate and the
body weight of swine, cattle and sheep.