Compound slow release preparation of pseudoephedrine, chlorphenamine and dextromethorphan

Abstract

The invention relates to a slow release preparation taking pseudoephedrine or physiologically acceptable salt thereof, chlorphenamine or physiologically acceptable salt thereof and dextromethorphan or physiologically acceptable salt thereof as active ingredients. The slow release preparation is characterized in that a releasing system comprises a tablet core and / or pill core capable of enabling a medicament to slowly release and a coating, wherein one part and / or all of the active ingredients exist in the tablet core and / or pill core, and the rest of the active ingredients exist in the coating.

Description

technical field [0001] The invention relates to a slow-release preparation with pseudoephedrine or its physiologically acceptable salt, chlorpheniramine or its physiologically acceptable salt and dextromethorphan or its physiologically acceptable salt as active ingredients. Background technique [0002] The common cold, called "cold" by the motherland's medical science, is a kind of respiratory common disease caused by multiple viruses, wherein 30%-50% is caused by a certain serotype of rhinovirus. Though common cold is mainly in early winter, in any season, as can taking place in spring, summer, the Causative virus of the flu of Various Seasonals is not just the same yet. The distribution of cold cases is sporadic, does not cause epidemics, and is often easily combined with bacterial infections. The onset of the common cold is rapid, and early symptoms include dry itching or burning sensation in the throat, sneezing, nasal congestion, runny nose, accompanied by sore throat...

AI Technical Summary

Problems solved by technology

Due to the short half-life of dextromethorphan, the general dose is 15-30 mg, which needs to be administered 3-4 times a day, and the blood concentration fluctuates greatly, which is likely to cause side effects

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