Medicine compounds for treating hypertension
A composition and high blood pressure technology, applied in the direction of drug combination, heterocyclic compound active ingredients, pharmaceutical formulations, etc., can solve the problems of reducing the survival rate of patients, the survival rate of hypertensive patients cannot be improved, and the loss of antihypertensive treatment, etc. Reduced incidence and severity of adverse reactions, reduced cardiac arrest and fatal and non-fatal stroke, effect of dose reduction
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Embodiment 1
[0022] Embodiment 1 hypertension compound tablet
[0023] Simvastatin 20g
[0024] Amlodipine 2.5g
[0025] Pioglitazone 20g
[0026] The rest of the pharmaceutical excipients are commonly used excipients for preparing tablets.
[0027] Preparation process: Prepared according to the conventional preparation process of photographic agent.
Embodiment 2
[0028] Embodiment 2 Hypertension Compound Capsules
[0029] Atorvastatin 10g
[0030] Enalapril 10g
[0031] Pioglitazone 20g
[0032] All the other pharmaceutical excipients are commonly used excipients for preparing capsules.
[0033] Preparation process: It is prepared according to the conventional preparation process of capsules.
Embodiment 3
[0034] Embodiment 3 hypertensive compound bilayer tablet
[0035] Simvastatin 10g
[0036] Mannitol 10g
[0037] Lactose 40g
[0038] Microcrystalline Cellulose 20g
[0039] 6% PVP in 95% ethanol solution 120g
[0041] Preparation process: Simvastatin passes through a 100-mesh sieve, mannitol, lactose, and microcrystalline cellulose pass through a 80-mesh sieve, weighs the prescribed amount of niacin and mixes them evenly with mannitol, lactose, and microcrystalline cellulose, and adds 6% PVP Appropriate amount of 95% ethanol solution is granulated, dried at 60° C., sieved with 16 meshes to dry the granules, and adding the prescribed amount of magnesium stearate to the dry granules.
[0042] Nifedipine 30g
[0043] Rosiglitazone 8g
[0044] Pregelatinized starch 50g
[0045] Mannitol 50g
[0046] 6% PVP in 95% ethanol solution 100g
[0047] Micronized silica gel 5g
[0048] Preparation process: Nifedipine and rosiglitazone pass through a...
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