161results about How to "No grittiness" patented technology

The invention relates to a method for extracting multiple active nutrient contents from sea cucumber processing liquid. The method comprises the following steps: raw material collection, primary filtration, enzymolysis, rough filtration, ultrafiltration, concentration, secondary rough filtration, desalination, fermentation, centrifugation, secondary enzymolysis, secondary centrifugation, third rough filtration, secondary ultrafiltration, secondary concentration and spray drying. The invention further relates to application of the method in orally disintegrating tablets. Compared with the prior art, the method has the advantages that a prepared sea cucumber extract contains multiple nutrient contents, and the total content of sea cucumber polypeptide, small proteins, sea cucumber mucopolysaccharide and sea cucumber glycosides reaches 80%-90%; in the whole technological process, reaction conditions are mild, no organic solvent is used, nutrient contents are hardly damaged, and molecules of the extracted sea cucumber extract are relatively small; after the sea cucumber extract is fermented by using beneficial bacteria, the nutrient contents in the sea cucumber extract are easily absorbed by human bodies, and almost no peculiar smell exists; furthermore, the technological process is very suitable for the industrial expanded production.

The invention discloses a nano fishbone product as well as a preparation method and application of the nano fishbone product, and belongs to the field of functional food. The preparation method of the nano fishbone product comprises the following steps of immersing cleaned fishbones in proper amount of water, stewing and softening the fishbones in a high-pressure digester, pouring out stewing liquid, adding water and rinsing, and draining off; breaking the fishbones with a meat grinder with the screen plate pore diameter of 2-10mm, drying, carrying out coarse grinding, and sieving by a 140-mesh sample separation sieve, thereby obtaining fishbone powder or fishbone paste with the particle size of less than 105 microns; and adding water into the fishbone powder or fishbone paste, regulating the water content of a dispersion liquid to 60-90%, and grinding by a high-energy ball mill at the speed of 2,000-3,000 rpm for 0.5-2 hours, wherein the size of the grinding medium is 0.5-5cm, and the filling content of the medium reaches 60%-80%. The nano fishbone product provided by the invention is emulsion which has no fishy smell, has the fishbone particle diameter of 100-300nm and has the calcium content of 30-50mg / g; the nano fishbone can be stably dispersed into the emulsion, has no gravel sense, and can be used for enhancing calcium in minced fish products and improving the texture property of the minced fish products.

The invention discloses an oral disintegration tablet of alcaine aminobromisuo, which contains alcaine aminobromisuo with effective dosage and pharmacological findings, wherein the alcaine aminobromisuo is processed by metarchon with rate of aminobromisuo and metarchon at 1: 0. 1-1. 5, which is blended with pharmacologically acceptable findings; the metarchon can be medically inorganic oxide or / and medicinal organic acid and salt; the acceptable findings is filler, corrigent, disintegration agent, adhesive and lubricant; the oral disintegration tablet of alcaine aminobromisuo hasn't bitterness and numb sense to disintegrate within one minute with stripping degree not less than 90%. The invention is convenient and simple to control with high yield and low energy consumption, which widens the resource of metarchon to save cost.

A dry particulate food composition comprising a gelling agent, at least one protein, at least one binding agent, at least one sweetening agent, a chemical gassing agent, and a chemical reagent for controlling and increasing a quantity of chemical gas released from the chemical gassing agent. The dry particulate food composition may additionally include at least one flavoring agent, at least one bulking agent, and at least one coloring agent. The dry particulate food composition may be mixed with a liquid to produce a food product.

The invention relates to a healthcare product combination for clearing and nourishing the throat and a preparation method thereof. The combination comprises the following raw and auxiliary materials in parts by weight: 25-75 parts of rosa roxbughii tratt powder, 100-200 parts of phyllanthus emblica powder, 40-250 parts of sorbitol, 200-900 parts of Isomalt, 1-10 parts of stevioside and 2-18 partsof magnesium stearate. The healthcare product combination for clearing and nourishing the throat, provided by the invention, has slightly astringent taste and sweet aftertaste.

The invention discloses a macitentan orally disintegrating tablet and a preparation method thereof. The orally disintegrating tablet is a drug mixture comprising macitentan, flavoring agent, filler, disintegrating agent, lubricant, wetting agent and binder, wherein the physiologically active ingredient macitentan is The weight percentage of disintegrating tablets is 5-10%. The solid pharmaceutical preparation provided by the invention adopts solid dispersion technology. By mixing and grinding the main drug and the filler, the solubility of the main drug is improved, the dissolution effect is improved, and the dissolution rate of the preparation is ensured. High content uniformity and high bioavailability. In addition, the macitentan orally disintegrating tablet with convenient administration, rapid onset of effect and high bioavailability of the present invention can improve the drug compliance of patients and is beneficial to the treatment of diseases.

The invention provides a pattern manufacturing method and a weaving system for textile. The method comprises the following steps: dividing an electronic image into a plurality of areas according to colors, putting the adjacent pixels with the color change smaller than tolerance into the same area, and putting the adjacent pixels with the color change not less than the tolerance into other different areas; filling one color in each area; and selecting a line with the color consistent to that of the area, and weaving the line into a pattern according to the electronic image. The invention also provides a weaving system comprising an image processing device and a weaving machine. In the invention, the image is divided into the plurality of areas, the line with the color consistent to that of the corresponding area is selected for the rear so as to wave the pattern, each area corresponds to one color in the pattern of the textile, the pattern of the woven textile has clear colors, does not has coarse color and grain feeling after various colors of lines are woven in a mixing manner, and is clear in outline and can be clear.

The invention relates to a method for improving the quality of macaroni made of rice. The method includes the steps of rice raw material preprocessing, smashing, rice protein powder preprocessing, mixing, silk extruding, aging processing, drying and airing. According to the method, the content of rice protein in products is increased, the rice protein is processed under the high-temperature alkaline condition, the added rice protein can well interact with starch and protein in raw material rice to form a network structure with certain strength, and therefore the processing characteristics and the quality of products are greatly improved in the process of producing the macaroni made of rice. The macaroni made of rice is of a hollow columnar structure, the two ends of the columnar structure are sealed, the surface of the macaroni made of rice is smooth, transparent and glossy or amber, when the macaroni is cooked, soup is clear and does not become pasted, the dissolving starch rate is reduced below 4% from 7.5%-8%, the surface of the macaroni is kept smooth, the macaroni is hard and elastic in taste, and the quality of the macaroni almost reaches or is higher than the related quality of macaroni made of wheat.

The invention discloses a riociguat orally disintegrating tablet and a preparation method of the riociguat orally disintegrating tablet. The disintegrating tablet is a medicinal composition containing riociguat, a filling agent, a disintegrating agent, a wetting agent, a binding agent, a corrigent and a lubricating agent. The preparation method adopts the wet granulation tabletting method. The invention aims at providing the riociguat orally disintegrating tablet which is simple in preparation process, low in cost, convenient to take, rapid in taking effect, and high in bioavailability; the dosage form can improve the medicine taking compliance of patients, and thus the treatment for diseases is benefited.

The present invention relates to orally quick disintegrating lornoxicam composition and its preparation process. The orally quick disintegrating lornoxicam composition includes lornoxicam in 100 weight portions, pharmaceutically acceptable lipoid taste mask 25-100 weight portions, and pharmaceutically acceptable disintegrating agent 50-500 weight portions. The present invention also provides the preparation process of the oral disintegrating lornoxicam composition. The composition of the present invention can disintegrate inside oral cavity in good taste and act in stomach. The composition of the present invention is easy taken, especially for those people with dysphagia.

The invention provides a phloroglucin orally disintegrating tablet and a preparation method thereof. The phloroglucin orally disintegrating tablet is prepared by adding a filler, a disintegrant, a binding agent, a lubricant and a stabilizer into phloroglucin used as an active component. The phloroglucin orally disintegrating tablet provided by the invention has the advantages of high disintegration speed, favorable mouthfeel, simple technological conditions and low equipment cost, and is suitable for large-scale production. The phloroglucin orally disintegrating tablet is convenient for special people, such as old people, patients with dysphagia or patients in particular cases, can greatly enhance the compliance of the patients, is beneficial to effective therapy, and can effectively lower the adverse effect caused by first-pass effect. The invention has the characteristics of high safety, controllable quality and the like, is effective, and is convenient to use.

The invention provides a phloroglucinol oral disintegrating tablet, which takes the phloroglucinol as the active ingredient, and disintegrating agents, fillers, lubricants, flavoring agents, binding agents and effervescent agents are added for preparation. The invention further provides a preparation method of the phloroglucinol oral disintegrating tablet. The phloroglucinol oral disintegrating tablet of the invention not only has the rapid disintegration, good taste and no sense of gravel, but can also can be taken under the condition of no water and have the rapid action and more convenient taking, so the invention can improve the compliance of the patients and the efficacy of the drug and other features of the orally disintegrating tablet, at the same time, the invention has light tablet weight, small volume, no powder falling, good brittleness and better dissolution effect than the freeze-dried orally disintegrating tablet. The production cost is low, the dissolution is faster, the invention is more beneficial to the absorption, and the invention can play the effect of pain reliving faster. The invention has the advantage that the invention can carry out the preparation by only adopting the ordinary pressing equipments and the simple technique without the need of special production equipments and conditions.

A quickly-releasing tablet of breviscapine for treating the acute cardiovascular and cerebrovascular diseases is prepared from breviscapine and the medicinal auxiliary able to promote the secretion of saliva.

A vaginal-applied interferon tablet for treating cervicitis, cervical erosion and viral vaginitis and its preparing process and disclosed. Its advantages are high curative effect and stability, simple preparing process and high solubility.

The invention relates to loratadine lyophilized tablets, and a lyophilization prescription and a technology thereof. The loratadine lyophilized tablets provided by the invention are prepared from a main medicine loratadine and medicinal auxiliary materials. When the tablets are taken, no water is used, and the tablets disintegrate rapidly in mouths. Therefore, the tablets are suitable for patients with swallowing difficulties such as old people and children. Also, the tablets are suitable to be used in trips with water source shortages. The tablets are advantaged in convenient administration, fast absorption, small first-pass effect, and small irritation to gastrointestinal mucous membranes. The market prospect of the tablets is wide. With the lyophilized tablets provided by the invention, side effects of loratadine can be substantially reduced. Also, the invention relates to a preparation method of the loratadine lyophilized tablets.

The invention provides an instant crocus sativus-containing solid drink and a preparation method thereof. The instant crocus sativus-containing solid drink is mainly prepared from the following raw materials in parts by weight: 5-80 parts of crocus sativus, 10-55 parts of excipient, 10-40 parts of an adhesive and 0.01-4 parts of a suspending agent, wherein the raw materials are dissolved and uniformly mixed with an appropriate solvent, and are dried, thereby obtaining the instant crocus sativus-containing solid drink. The instant crocus sativus-containing solid drink provided by the invention not only solves the problems that crocus sativus is not easy to carry over or store and single in healthcare effect, and moreover has the advantage of instant solubility.

The invention relates to rotundine orally disintegrating tablets and a prescription and process for preparing the rotundine orally disintegrating tablets by adopting a freeze drying method. The rotundine orally disintegrating tablets are prepared from rotundine as a main medicine and pharmaceutic adjuvants, can be taken without water, are capable of rapidly disintegrating after entering the mouth, are suitable for taking by patients suffered from dysphagia, such as the old, children and the like, are simultaneously suitable for medications in the travel journey under the condition of being not easy to obtain a water source, has the advantages of convenience for taking, high absorption speed, small fast pass effect, little irritation to digestive tract mucosa, wide market application prospect and the like, and are capable of remarkably reducing side effects of rotundine. In addition, the invention also relates to a preparation method of the rotundine orally disintegrating tablets.

The invention relates to a Chinese medicinal chrysanthemum buccal tablet. 1000 buccal tablets of the invention are prepared by the following raw materials by weight: 100g of chrysanthemums, 1-500g of a filling agent, 1-40g of an adhesive, 1-10g of a glidant, and 0.1-2g of a lubricating agent.

The present invention relates to a kind of dragoní»s blood gel preparation comprising dragoní»s blood in effective dosage as main medicine and gel mixed together. The preparation process includes dispersing polymer material as gel matrix inside solvent for full swelling, adding pH regulator to reasonable range, and adding preservative and permeation promoter to form gel; adding fine dragoní»s blood powder and mixing homogeneously. The dragoní»s blood gel preparation may be used in treating traumatic injury, bedsore, epidermis ulcer, chronic cervicitis and other diseases. The dragoní»s blood gel preparation has excellent skin adhesion, excellent spreading property, high permeation and high transdermal absorption effect.

The invention relates to a topiramate dry suspension. The topiramate dry suspension is prepared by multi-stage mixing granulation, and comprises topiramate, an inert carrier, a disintegrating agent, ataste masking coating, a pore-foaming agent, a filling agent and a suspending aid, wherein the topiramate, the inert carrier, the disintegrating agent and the taste masking coating form taste maskingparticles, so that the bitter taste of topiramate can be effectively solved. The topiramate dry suspension at least comprises two filling agents which have the functions of forming a suspending aid component and reducing the wall adhesion condition of the dry suspension, and the topiramate dry suspension is found to be convenient to prepare for the first time, improves the compliance and administration accuracy of patients and is suitable for industrial production.

The invention discloses a flaky toothpaste additive with icy mint flavor and a preparation method thereof. The preparation method comprises the following steps: dissolving 2 to 12 weight portions of esters in 400 to 2,000 weight portions of deionized water at a temperature of between 50 and 80 DEG C, reducing the temperature of the solution to a temperature of between 20 and 30 DEG C, adding 0.04 to 0.2 weight portion of a preservative, 0.4 to 4 portions of a dispersant, 4 to 20 weight portions of mint oil, and 4 to 30 weight portions of a plasticizer into the solution, and stirring the solution evenly to obtain oil phase slurry; pouring the oil phase slurry into dispersion fluid of modified cellulose and colorant for carrying out high-speed dispersion for 30 to 60 minutes; adding the evenly dispersed cellulose latex into a carrier, roasting the latex and the carrier for 20 to 45 minutes, and then taking out a cellulose film which is cut into the flaky toothpaste additive. The toothpaste additive has the advantages that the toothpaste has excellent hydrophilic / hydrophobic balance, high rate of disintegration in the oral cavity, and no sand feel; in addition, the toothpaste additive can be stably stored in the toothpaste for a long time with good resistance to the swellability of the toothpaste.

The invention relates to an eEnteric coated orally disintegrating tablet of aspirin wherein the orally disintegrating tablet comprises physiological effective dose of enteric-coated aspirin and pharmaceutically acceptable carrying agents suitable for preparing orally disintegrating tablet, which comprises macromolecular material, bulking agent, crumbling agent, effervescent agent, lubricating agent, flavoring agent, and other pharmaceutically acceptable carrying agents suitable for preparing orally disintegrating tablet.

An oral disintegrating tablet of the common flavone of haw leaf is prepared from said common flavone, filler, disintegrant, effervescent agent, lubricant and flavouring through proportionally mixing, and die pressing.

The invention discloses a preparation method of panax quinquefolius raw powder tablets, and belongs to the technical field of health care products. The method comprises nine steps: sorting, cleaning, drying, crushing, grinding, granulating, mixing, tabletting and sterilizing. The panax quinquefolius raw powder tablets do not contain any auxiliary materials; the bioavailability of product is increased; the product is more convenient to use, with longer guarantee period, lower processing cost, good dispersibility, miscibility and absorbability, thus the effective constituents of panax quinquefolius enter human body quickly; the original taste is reserved, and the health care function is increased; moreover, the dosage can be exponentially reduced, thereby effectively increasing utilization ratio of rare resources.

The invention relates to a riluzole orally disintegrating tablet and a preparation method thereof, and belongs to the field of preparations. The tablet is prepared from riluzole, sodium bicarbonate, afilling agent, a disintegrating agent, a lubricating agent and a flavoring agent. The preparation method comprises the following steps of (1) weighing riluzole, sodium bicarbonate and filler according to prescription amounts, and uniformly mixing the riluzole, the sodium bicarbonate and the filler with 50% of the disintegrating agent according to prescription amounts for later use; 2) adding themixture obtained in the step 1) into an ethanol water solution, granulating, drying, and sieving to obtain dry granules for later use; and 3) adding 50% of a prescription amount of the disintegratingagent and a prescription amount of the flavoring agent into the dry particles obtained in the step 2, uniformly mixing, adding a prescription amount of the lubricant, uniformly mixing, and pressing toobtain the riluzole orally disintegrating tablet. The orally disintegrating tablet prepared by the invention has the advantages of short disintegration time limit, high dissolution rate and no gravelfeeling, meets the quality standard requirement of the orally disintegrating tablet, and is suitable for industrial scale-up production.

An oral disintegrating tablet for nisoldipine for treating coronary heart disease, hypertension, ischemic heart disease and congestive heart failure is prepared from nisoldipine, souring agnet, excipient and disintegrant.

An orally disintegrating tablet of 5-HT receptor agonist and a preparation method thereof are disclosed. The invention relates to an orally disintegrating tablet of 5-HT receptor agonist as well as a prescription and a process for preparing the orally disintegrating tablet of 5-HT receptor agonist by a freeze-drying method. The orally disintegrating tablet of 5-HT receptor agonist disclosed by the invention is prepared from main medicines and pharmaceutical excipients, without the need of water while administration, capable of being rapidly disintegrated in mouth, and suitable for the administration of patients with difficulty in swallowing, such as the old and children; simultaneously, the orally disintegrating tablet of 5-HT receptor agonist is suitable for administration in a condition that water is not easy to obtain during travelling; and the orally disintegrating tablet of 5-HT receptor agonist has the advantages of being convenient to take, fast in absorption, small in first pass effect, small in irritation on digestive tract mucosa and the like, as well as has wide market application prospect. Moreover, the orally disintegrating tablet of 5-HT receptor agonist disclosed by the invention can obviously reduce the side effects of 5-HT receptor agonist. Additionally, the invention further relates to a preparation method for the orally disintegrating tablet of 5-HT receptor agonist.

The invention discloses a donepezil hydrochloride orally disintegrating tablet. The main medicine of the donepezil hydrochloride orally disintegrating tablet is donepezil hydrochloride; and the auxiliary medicines of the donepezil hydrochloride orally disintegrating tablet comprise mannitol, microcrystalline cellulose, hyprolose, crospovidone, sodium bicarbonate, citric acid, soluble saccharin, carboxymethyl starch sodium, magnesium stearate and essence. The invention can preferably treat the low-degree or moderate-degree alzheimer type dementia, can preferably improve the cognitive dysfunction, the mental and behavioral abnormalities and the daily self-care ability of the patient who suffers from the alzheimer type dementia (AD), can alleviate the dementia degree, is convenient to take, can fast disintegrate, and is convenient for the old or the patient who has medication obstacles or is hard to take water.