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3183results about How to "Low cost of treatment" patented technology

TCR<->(T Cell Receptor)/PD-1<-> double-negative T cell and construction method thereof

ActiveCN106191062APre-preparation on a large scaleLow cost of treatmentAntibacterial agentsImmunoglobulin superfamilyMolecular biologyAdoptive Cell Immunotherapy
The invention discloses a TCR<->(T Cell Receptor) / PD-1<-> double-negative T cell and a construction method thereof. Separated peripheral blood mononuclear cells are activated into T cells and TCRs and PD-1 are knocked out through a CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) / Cas9 gene editing technology; the TCR<-> / PD-1<-> double-negative T cell is separated through a magnetic bead. The TCR<-> / PD-1<-> double-negative T cell prepared by the invention can be used for adoptive cell immunotherapies of tumors, including DC-CIK (Cytokine-Induced Killer), CTL (Cytotoxic T-Lymphocyte), TIL (Tumor Infiltrating Lymphocytes), CART (Chimeric Antigen Receptor Therapy) and the like. The TCR<-> / PD-1<-> double-negative T cell disclosed by the invention can be selected from other homologous and xenogenous healthy donators, so that the cell gets rid of limitation of current disease conditions of patients when being applied to the adoptive cell therapy; the cell can be prepared in a large batch in advance and the therapy cost is reduced.
Owner:GUANGZHOU ANJIE BIOMEDICAL TECH CO LTD

Spiral reverse osmosis membrane element, reverse osmosis membrane module using it, device and method for reverse osmosis separation incorporating the module

A spiral reverse osmosis membrane element of the present invention includes a plurality of bag-shaped reverse osmosis membranes, permeated liquid passage members arranged inside the reverse osmosis membranes, and a plurality of feed liquid passage members interposed between the reverse osmosis membranes, those membranes and passage members being wound around an outer surface of a hollow pipe in a manner that only the interiors of the reverse osmosis membranes communicate with through-holes formed in the surface of the hollow pipe. Each of the feed liquid passage members is a mesh member having series of quadrilateral meshes formed by a plurality of linear members crossing each other. Two opposite cross-points out of four cross-points of each of the quadrilateral meshes are in line in parallel with an axial direction of the hollow pipe. And relations 2 mm<=X<=5 mm and X<=Y<=1.8X are both satisfied where X denotes a distance between the cross-points in a direction perpendicular to the axial direction of the hollow pipe and Y denotes a distance between the cross-points in the axial direction of the hollow pipe.
Owner:TORAY IND INC

Motor function rehabilitation monitoring system based on wireless body area network

The invention discloses a motor function rehabilitation monitoring system based on a wireless body area network. The system comprises a sensor terminal node, a wireless gathering node, a wireless body area network gateway, a personal terminal, a remote medical terminal and an information feedback system, wherein the sensor terminal node comprises a medical sensor, a signal conditioning circuit, a microprocessor unit and a wireless transceiver unit which are sequentially connected, the medical sensor sends collected data into the signal conditioning circuit for preprocessing, and the wireless transceiver unit is controlled to perform wireless transmission after the data is processed by the microprocessor unit; the data collected by the sensor terminal node sequentially passes through the wireless gathering node and the wireless body area network gateway and is respectively transmitted into the personal terminal and the remote medical terminal, and the data is transmitted into the information feedback system after being processed by the remote medical terminal, and is displayed by a 3D model built through the information feedback system. The monitoring system can be used for monitoring the exercise rehabilitation situation of a patient in real time, providing reasonable guidance and advices for subsequent rehabilitation training and improving the rehabilitation training effect.
Owner:NANJING UNIV OF POSTS & TELECOMM

Chinese herbal medicine for treating cellulitis

The invention discloses a Chinese herbal medicine for treating cellulitis. The Chinese herbal medicine is prepared from the following medicines in parts by weight: 25-35 parts of honeysuckle, 25-35 parts of wild chrysanthemum, 25-35 parts of dandelion, 15-25 parts of Philippine violet herb, 5-15 parts of semiaquilegia adoxoides makino, 25-35 parts of goldthread root, 25-35 parts of radix scutellariae, 25-35 parts of amur corktree bark, 15-25 parts of cape jasmine, 15-25 parts of climbing groundsel herb, 10-25 parts of broomjutre sida herb and 15-25 parts of all-grass of Japanese violet. The Chinese herbal medicine is prepared by adding 1800 parts by weight of water, after the water is boiled, decocting the medicines with slow fire for 20-30 minutes, filtering the decoction and collecting the supernatant, adding 1800 parts by weight of water and decocting the supernatant three times, uniformly mixing the supernatant decocted three times, then bottling the supernatant respectively and sterilizing the supernatant under a high temperature for later use. Honeysuckle is taken as the monarch, dandelion and wild chrysanthemum are taken as the ministers, Philippine violet herb, semiaquilegia adoxoides makino, goldthread root and radix scutellariae are taken as the assistants, and amur corktree bark, cape jasmine, climbing groundsel herb, broomjutre sida herb and all-grass of Japanese violet are taken as the guides. The Chinese herbal medicine has the following beneficial effects: the Chinese herbal medicine is convenient to prepare and use, is safe and does not have side effects.
Owner:CHONGQING NANCHUAN DISTRICT RUIFENG AGRI DEV

Medical grinding cutter

ActiveCN103767759ARealize universal orientation adjustmentImprove adaptabilitySurgerySurgical siteEngineering
The invention discloses a medical grinding cutter. The cutter comprises a knife tube component and a grinding head, wherein the grinding head is mounted at the front end of the knife tube component; the grinding head can be driven for pitching and self-rotation; the tail end of the grinding head in the circumference direction is hinged to an inner knife tube in a transmission manner; a flexible transmission section is positioned at the front end of the inner knife tube and used to be hinged to the tail end of the grinding head, and can transfer torque. According to the invention, the medical grinding cutter adopts a direct hinging structure to transfer the transmission between the inner knife tube and the grinding head, can conduct a pitching motion, and adopts a flexible transmission structure to compensate axial deviation caused by pitching and transmission; the transmission structure is simple, and the transmission chain is shorter, which facilitates stable control, so that the operative efficiency is improved; the medical grinding cutter also adopts a structure capable of adjusting both the pitching and circumferential positions of the grinding head, so that the universal orientation adjustment is realized; the medical grinding cutter has a good adaptation to an operative site and higher precision; the operative process efficiency can be improved; the pain of the patients can be minimized, and meanwhile, the treatment cost can be reduced.
Owner:CHONGQING XISHAN SCI & TECH

Chinese medicinal preparation for treating urolithiasis and preparation method thereof

InactiveCN101884770AGood synergyTo achieve the effect of diuresis, dredging and excreting stonesAnthropod material medical ingredientsInanimate material medical ingredientsDiuresisAkebia Stem
The invention discloses a Chinese medicinal preparation for treating urolithiasis, which is prepared from niter, chicken's gizzard-membrane, alum, gardenia jasminoides, Japanese climbing fern spore, longhairy antenoron herb, cluster mallow fruit, herba pyrrosiae, virgate wormwood herb, amber, cuttlebone, pangolin scales, cowherb seed, spreading hedyotis herb, frankincense, myrrh, white paeony root, lalang grass rhizome, clematis root, corydalis root, radix curcumae, talc, pink herb, medicinal cyathula root, giant knotweed rhizome, astragalus, mongolian dandelion herb, mole cricket, plantain seed, herba polygoni avicularis, yellow croaker ear-stone, common burreed rhizome, zedoary, gleditsia thorn, dried orange peel, ephedra, oriental waterplantain rhizome, chinese waxgourd peel, notoginseng root, agaric, Chinese eaglewood, akebia stem, rhubarb and India madder root in a certain weight ratio. The Chinese medicinal preparation can be prepared into any common oral administration formulation. In a formula of the Chinese medicinal preparation, the medicaments have the good synergistic effect on the curative effect through reasonable compatibility, so the effects of inducing diuresis, treating stranguria and removing urinary calculus are achieved better, and the symptoms are removed. Compared with the prior art, the Chinese medicinal preparation has the advantages of quick response, high cure rate, relapse prevention, no toxic or side effect, low treatment cost and easy acceptance by patients.
Owner:马全义

Hollow fiber ultrafiltration composite membrane, preparation method and application thereof

InactiveCN101703893AStrong resistance to solute pollutionImprove blood compatibilitySemi-permeable membranesDialysis systemsUltrafiltrationChemistry
The invention relates to a hollow fiber ultrafiltration composite membrane composed of the components in the following weight percent: 15-25% of membrane material, 5-15% of pore-making agent, 55-75% of organic solvent and 5-10% of lithium chloride; the membrane material is a mixture of chitosan and one of polysulfone, polyether sulfone, polyacrylonitrile, polymethyl methacrylate, or cellulose triacetate, wherein the chitosan accounts for 1-5% of the total weight of the raw material, and the average molecular weight of chitosan ranges from 300,000 to 1,000,000; the pore-making agent is one of polyvinylpyrrolidone, polyethyleneglycol, or polyvinyl alcohol, or a mixture thereof; and the organic solvent is one of N-methyl-2-pyrrolidone, dimethyl fomamide, dimethyl acetamide, or dimethyl sulfoxide. The invention has good bioactivity, biocompatibility, anti-coagulation property and other properties.
Owner:江苏朗生生命科技有限公司

3D navigation equipment for non-invasive real-time operation positioning

The invention relates to 3D navigation equipment for non-invasive real-time operation positioning, which is characterized by comprising a laser positioning system and a space positioning device, wherein the laser positioning system is composed of a laser driving device, a work server, a digital signal shunt and a display, the laser driving device is in Bluetooth communication with the work server, and the work server, the digital signal shunt and the display are electrically connected; and the space positioning device is composed of a fixing slide rail, a two-way slide rail, a two-degree-of-freedom fixing slide block, a two-degree-of-freedom two-way slide block, a laser positioning rod and an operation channel which are mutually matched. According to the invention, path planning before an operation is realized through a computer, and an operation path can be spatially positioned accurately by visualized real-time registering of a focus point in the operation by the laser positioning system as well as the angle and depth control of the space positioning device; and the system is suitable for minimally-invasive orthopedic operations of any parts of patients.
Owner:HANGZHOU SANTAN MEDICAL TECH
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