811 results about "Blood transfusion history" patented technology

A dislodgement sensor for use with dialysis and other blood transfusion equipment that detects when a venous needle is dislodged from a patient. The sensor includes a photosensor attached to the venous needle or to tubing attached to the venous needle, an opaque cover placed over but not attached to the photosensor, and a signal line from the photosensor to the equipment. If the venous needle is dislodged, the photosensor is withdrawn from beneath the opaque cover, exposing the photosensor to light, which causes the photosensor to send a signal to the equipment indicating that the venous needle has been dislodged. Also, a method of using such a sensor.

A three-way stopcock that can be opened / closed in the same manner as conventional operation methods and can reduce stagnated portions of fluid in a fluid flow passage. Out of branch openings, a first branch opening and a second branch opening are arranged on a straight line, and a third branch opening is directed perpendicularly to the line connecting the first and second branch openings. Provided at a flow passage switch portion are a first flow-passage opening and a second flow-passage opening that are arranged on a straight line and a third flow-passage opening that is directed perpendicularly to the line connecting the first and second bran openings.

The present invention discloses one kind of composite material of modified micro plant fiber powder and natural rubber and its preparation process and application. The composite material includes natural rubber or latex 100 weight portions, modified micro plant fiber powder 1-60 weight portions, sulfur 0.5-3.3 weight portions, promoter 1.2-4.3 weight portions, antiager 1-3 weight portions and other assistant. The preparation process includes mixing, forming, vulcanizing and other steps. The composite material has high tensile strength, high tearing strength, high ageing resistance, high virus permeation resistance, etc. and may be used widely in making urinary catheter, blood transfusion tube, condom, medical gloves and other products.

A method and a system for using RFID (Radio Frequency Identification) in the workflow of a blood center and a medical institution from a network Customer Relationship Management (CRM) information system. The CRM comprises an RFID technique system, a computer database system, and a computer information network. The information transferred between an integrated circuit and a reader-writer occurs through the radio waves in the workflow of, for example, a blood center or other medical institution. The related information ranges from identity information to biological product information. In each procedure of the blood collecting and supply workflow, the information is read / written by the computer into electronic tag and through the computer information network into the service management information system. The work flow of blood centers (stations), such as blood test reports before and after blood transfusions and the desired information of people and objects involved in blood transfusions, can thereby be recorded completely, integrally, precisely, and comprehensively by the RFID system.

The invention relates to a medical coating layer coated on the gasbag surface of a balloon pipe which can release the narrowing of blood vessel and reduce free radical damage after operation, belonging to the field of the medical instruments, which comprises 1% to 99% of medicine and 1% to 99% of medical carrier, wherein the medical comprises a single oxidation resisting medicine, or a mixture of a plurality of oxidation resisting medicines, or a mixture of a single or a plurality of oxidation resisting medicines with blood vessel narrowing resisting medicines; the medicines are evenly coated on the surface of the gasbag all together or layer by layer. The medical coating layer coated on the gasbag surface of a balloon pipe has the advantages that through local medication the damage to human cells and organizations after blood transfusion due to myocardial ischemia can be effectively released and reduced and the cardiac dysfunction can be finally cured.

The invention discloses a thrombelastogram instrument, which comprises a structural module comprising a structural framework and an auxiliary motion execution mechanism, wherein the auxiliary motion execution mechanism is used for realizing cup loading, elevating and cup unloading motion of a test cup; a measure module comprising a measure assembly, a cup holder assembly, a level meter and a temperature controller; a signal control module comprising an amplification plate and a main control board; a storage processing module comprising host computer hardware; and an auxiliary module comprising a power supply, a switch, a button connecting line and an interface. The thrombelastogram instrument has the advantages of strong integrated level of a system, high automation degree and good anti-interference performance, clotting panorama of patients can be comprehensively detected, curative effect of certain medicines relative to blood clotting can be monitored, medicine or blood transfusion scheme can be adjusted, treatment scheme can be rapidly determined, patient cost is simultaneously reduced, detection period is shortened, treatment time is saved, and life span can be prolonged.

The invention discloses the application of a CRISPR / Cas9 carrier combination in preparation of a blood product of a gene knockout pig. The gene knockout pig is a pig without GGTA1 genes, CMAH genes and beta4Ga1NT2 genes. The CRISPR / Cas9 carrier combination comprises a GGTA1-CRISPR / Cas9 carrier, a CMAH-CRISPR / Cas9 carrier and a beta4Ga1NT2-CRISPR / Cas9. By designing a specifically targeted SgRNA sequence, the knockout efficiency of the three genes is respectively 56 percent, 63 percent and 41 percent; after the three genes relating to immunological rejection are knocked out, the gene knockout pig is obtained; the combination between erythrocytes and immune globulin in human serum is obviously reduced; an outstanding effect is achieved to overcome hyperacute immunological rejection; the problem of clinical ischemia is effectively solved; a precious material source is provided for clinical blood transfusion.

The present invention relates to a medicinal transfusion system with heating body positioned under the Murphy's dropper, said heating body adopts electric resistance heating wire or electric heating tube or far infrared heater or ceramic heater or radio-frequency heater or semiconductor heater or other liquid heat source which can enure that the temp. of blood or liquid medicine for transfusion is approximate to body temp. so as to completely eliminate the blood transfusion and fluid infusion reaction due to infusion of low-temp fluid.

The invention relates to an automatic labeling device in blood sample separation, which comprises a frame, a test tube rotating disk, a scanner, a single chip microcomputer, a printer, a label-delivering mechanism, a label paper tape, and a label paper stop block; the scanner collects bar code information on a blood sampling bag; the printer prints the collected bar code information on a non-setting adhesive label on the label paper tape; a plurality of test tube mounting holes are disposed on the test tube rotating disk; the label-delivering mechanism is provided with a guide roller, a tension wheel supporting the label paper tape, and a pressing wheel; the guide roller is driven by a motor to rotate and deliver the label paper tape; the label paper stop block is mounted near the edges of the test tube mounting holes. The invention integrates scanning, printing, positioning, and labeling, can ensure that the bar code information of a same blood sample is accurate and unique on each of the test tubes during blood sample separation and reservation, thus effectively ensures the safety of blood transfusion, and ensures the life safety of a blood receptor. The invention has reasonableconstruction and convenient operation, and is especially applicable to disposable blood sample separation.

The invention discloses a method for preparing epoxidized soybean oil or epoxy fatty acid methyl (ethyl) ester through the catalysis of organic rhenium oxide-urea peroxide, which belongs to the technical field of liquid-phase catalytic epoxidation. The method utilizes a biomass material, namely soybean oil or unsaturated fatty acid methyl (ethyl) ester, adopts organic rhenium oxide as a catalyst, utilizes urea peroxide to react to synthesize the epoxidized soybean oil or the epoxy fatty acid methyl (ethyl) ester under the conditions without carboxylic acid and protonic acid, and avoids the use of strong acid catalysts during the epoxidation, so the method has small corrosion on equipment; the method avoids the use of the carboxylic acid, makes the post-treatment simple, and has no wastewater; and the method ensures that the process has simple operation, meets the requirement of epoxidized clean production, and is environment-friendly. The product can be taken as a plasticizer to be widely applied to nontoxic polyvinyl chloride (PVC) products and transparent PVC products, namely industrialized products such as transparent bottles, transparent boxes, food and drug packing materials, medical PVC 'blood transfusion bags', environment-friendly photocurable coatings and the like.

Decades of investigations were focused on finding “gold standard” for evaluation of plasma dilution and osmolality, blood loss evaluation and prediction of bleeding or transfusion induced changes in hematocrit and hemoglobin concentration. Addressing deficiencies of existing methods, the current invention created new combined mathematical-physiological model applicable to manually operated nomograms and software in medical monitors. The mathematical model HBS Trends is used in blood transfusion and infusion therapy nomogram—HBS Nomogram—which is based on blood hemoglobin concentration and hematocrit. It is also an easy and practical tool for recording and dynamical interpretation of plasma osmolality, blood hemoglobin concentration, hematocrit and mean corpuscular hemoglobin concentration. The HBS Nomogram is a practical system for organizing blood test results in a patient's medical records. It can be used alone or, in line with existing guidelines for infusion and transfusion therapy making them more practical, cost effective and time saving in decision making.

A soft polyvinyl chloride plastics for blood transfusion device, such as blood bag, is proportionally prepared from PVC resin, phthalate, trimellitate, citrate, epoxy soybean oil, composite Ca-P stabilizer and silicon oil. Its advantages are no erythrocatalysis, high stability of trimellitate, and low toxin.

A targeted iron chelator delivery system that comprises an iron chelator, a targeting agent and a lipid carrier, e.g., a liposome, is provided. The iron chelator delivery system may be used to remove excess iron from specific organs such as, for example, heart and liver tissue. Methods for preparing and administering the targeted iron chelator delivery system are also provided. The iron chelator delivery system may be administered during a blood transfusion to prevent iron overload.

The invention discloses an RFID blood management system which comprises an RFID scanning module, a communication system, and a blood collection system, a blood-bank-in system, a blood-bank-out system, a blood use system, a reserve management system, a blood information tracking system, a blood station monitoring system and a query system connected with the communication system. Via RFID codes, bank-out information of blood and entire information of a blood user can be found, and blood information is tracked; RFID blood bags are prepared, each link in transport, storage and sue is loaded in an RFID chip, and blood source information can be uploaded to a blood center database via the GSM network; and thus, information in the whole blood transfusion and supply process is shared, the blood transfusion and supply process is controllable, and the safety and supervision performance of medical blood transfusion and supply are improved.

The invention discloses an intelligent management control method for clinical blood transfusion electronic information system, which belongs to an implementation method of innovation of clinical blood transfusion application, evaluation, blood transfusion program proposal, and blood transfusion process supervision and evaluation, the method mainly includes: detecting project applications and managing specific instruction of the blood application before blood transfusion; evaluating and suggesting blood transfusion program; collecting blood sample and verifying identification; recording blood transfusion process and adverse reaction; and evaluating curative effect after blood transfusion. The method further implements and improves the specific management measures corresponding to blood transfusion management regulations, and ensures the safety and rationality of blood transfusion, and greatly improves the rationality of the clinical blood transfusion, and validity and the operability of safety management.

The blood temperature varying system based on distributed computer control consists of one extracorporeal blood circulation subsystem and one monitoring subsystem. The extracorporeal blood circulation subsystem includes a blood transfusion pipe, a heat exchanger, a water pump, an oxygenator, a post blood treater and a centrifugal pump. The monitoring subsystem includes a flow sensor, a heating / cooling device, a centrifugal pump rotation controller, a host control computer for precise temperature control, information display and data saving, and a multi-point temperature measuring instrument.

The invention belongs to a biodegradable nano-particle bonded with a hemoglobin molecule, and a method for preparing the biodegradable nano-particle. A polyethylene glycol polyester copolymer with such active functional groups as carboxy groups, amino groups, hydroxyl groups, triple bonds and so on in lateral chains is assembled to form micelle, and the micelle is bonded with the hemoglobin molecule; or firstly, the polyethylene glycol polyester copolymer is bonded with the hemoglobin molecule and then is assembled to get a chemical bonded hemoglobin nano-particle system. The size of the nano-particle prepared ranges from 80nm to 800nm. The hemoglobin accounts for 100 to 500 percent of the nano-particle by weight; the viscosity of the solution ranges from 1MPs to 4MPs; the salt content ranges from 50mM to 200mM; the pH value ranges from 7.0 to 7.6; the oxygen Affinity ranges from 6mmHg to 50mmHg; the stable half life of the hemoglobin ranges from 15 to 24 hours. The bonded hemoglobin nano-particle can be used for manual transmission of oxygen, and as an erythrocyte simulator, which can be used for clinical blood transfusion and to cure cardiovascular and cerebrovascular diseases.

The application discloses a blood transfusion volume model building and prediction method and device, equipment and a storage medium thereof; the method comprises the following steps: obtaining a history user data set in a preset period, and dividing the history user data set into a training data set and a test data set; extracting at least one feature parameter set according to the history user data set, wherein the feature parameter set does not include an operation consumption time; using the training data set and the test data set for learning and verification via a model training algorithm, thus obtaining a mapping relation between the at least one feature parameter set and a single user blood transfusion volume, and using same as the blood transfusion volume prediction model. According to said method, the mapping relation between the at least one feature parameter set and the single user blood transfusion volume can be built and used as the blood transfusion volume prediction model, thus adapting to various infusion scenes in the medical field. The prediction model can reduce the erythrocyte ultra indication infusion proportion and variant blood transfusion risks, thus savingblood resources.

The invention discloses a method for detecting a Miltenberger blood group antibody. The method comprises the steps of coupling nano magnetic beads with avidin to form avidin magnetic beads; coupling the avidin magnetic beads with a multipeptide antigen with a biotin-modified tail end, and closing non-coupled sites to obtain immune magnetic beads; uniformly mixing the immune magnetic beads with a detection sample, then performing incubation and washing, adding fluorescence labeled second antibody or enzyme-labeled second antibody, performing incubation and washing, and measuring a result. In the mode, the method for detecting the Miltenberger blood group antibody based on nano magnetic bead immunoassay is low in operation difficulty and is simple and convenient to operate, can be used for simultaneously detecting complete antibodies and incomplete antibodies; the detection process is short in time, and the result is easy to judge; automation is easily realized, and the detection result is accurate; in combination with a detector, semi-quantitative or quantitative detection can be realized; clinical safe, effective and scientific blood transfusion can be guaranteed.

The present invention provides a reagent set with the test method and test before a blood transfusion, is a method to improve the traditional manual polybrene method and the detection sensitivity of the detection reagent set, the cleaning liquid reagent set comprising blood, a solution of low ionic medium, polybrene solution and resuspension solution. The method and reagent set of the present invention made without clinical significance of antibodies has a lower detection sensitivity, but the clinical significance of the antibody has a high detection sensitivity, thus reducing the workload for the subsequent identification of the antibody, reducing testing costs, giving patients more secure rapid transfusion quality.

This invention prevents the danger of falling of body temperature by making the blood temperature similar to the body temperature in the injection of Ringer's solution fluid or blood transfusion, and also alleviates the patient's pain and improves the speed at which Ringer's solution fluid or blood enters the body. The warming device is much cheaper than previously released products, and small and light in weight, and allows blood or solution fluids to flow most effectively by allowing sufficient time for heat transfer as a pack type. The operation is convenient and sanitary in its single usage only. The inventive purpose has the methods of utilizing the temperature sensor in adjusting temperature by utilizing them PTC heating element's resistance specialty against the temperature as well as temperature sensor.

The invention discloses a double-saccule blood vessel inner conduct pipe wherein the pipe is provided with an opening on one end, and a securing sleeve on the other end, the outer wall of the pipe is covered by a first saccule and a second saccule spaced by a finite distance on the opening end of the pipe, the saccule tube connector is inserted into the inner cavity of the pipe through the securing sleeve and is in communication with the inner cavities of the two saccules. The pipe is provided with a blood output hole, which is provided with a blood transfusion tube.

The invention relates to medical injection, in particular to a compound sodium acetate injection used for venoclysis. The injection is made of the materials with the weight ratio: 5.32g-5.88g of sodium chloride, 0.285g-0.315g of potassium chloride, 0.266g-0.294g of calcium chloride, 0.19g-0.21g of magnesium chloride and 5.035g-5.565g of sodium acetate; and the water used for injection is added up to 1000ml. Compared with the prior art, the pH value, the permeation pressure and the electrolyte of the compound sodium acetate injection are the closest to the pH value of blood plasma of human body, so that the compound sodium acetate injection can be widely suitable for various patients in a stress state, diabetes patients or hypoglycemia patients and children, and used for washing pipe when in blood transfusion. Furthermore, the compound sodium acetate injection has little incompatibility, low cost, wide application prospect and foreseeable great social and economic benefits.

The invention relates to the technical field of medical treatment, and discloses a detection and evaluation method applicable to blood management of perioperative patients. The method comprises the following specific steps: S1, reading admission records, nursing documents, blood routine examination results and blood coagulation and biochemical information of a patient from a MySQL database, and conducting aggregating; and S2, evaluating whether the structured test indexes of the patient meet requirements on preoperative autologous blood collection or not. According to the invention, a doctor in a blood transfusion department can be helped to understand the blood use law of a single disease in each department of the hospital, and the doctor can be helped to formulate an optimal blood transfusion path through optimal postoperative hemoglobin analysis; clinical doctors can know the conditions of anemia and blood coagulation functions of the patient before an operation, and timely and pertinently treat the patient to ensure smooth operation in the operation, and rehabilitation of the patient can be accelerated; a doctor is helped to know an autologous blood collection scheme and intraoperative recovery feasibility in advance, the use probability of allogeneic blood is greatly reduced, and the risk of various adverse reactions is reduced.

The invention discloses a primer group and a kit for detecting a human platelet alloantigen (HPA) gene. The primer group for detecting the human platelet alloantigen (HPA) gene comprises an HPA-6a primer pair, an HPA-6b primer pair, an HPA-15Gova primer pair, an HPA-15Govb primer pair and an internal reference primer pair. The kit of the invention realizes platelet genotyping and has great significance for effectively avoiding platelet specific immunity and selecting to transfuse blood products matched with HPA genotypes in clinical and blood transfusion.

The invention relates to a collecting and displaying device for hand vein images, which consists of a near infrared image collecting module, a near infrared lighting module, an image processing module and a visible light projecting and displaying module. A medical device based on an optical instrument is formed by integrating a near infrared reflective image collecting system with a visible light projecting and displaying system effectively. The collecting and displaying device for hand vein images can be widely applied to medical means such as injection, blood drawing and blood transfusion for hand veins of human bodies.

The invention discloses a disposable automatic streaming-stopping liquid-residue-prevention type blood transfusion apparatus. The disposable automatic streaming-stopping liquid-residue-prevention type blood transfusion apparatus is composed of a liquid incoming port, a blood filter, a dripper, a float valve, an infusion tube, a dripping speed regulator, a liquid outgoing port, a closed air leading mechanism, a container imitating type bottle rinsing drip apparatus and a manual pressure pump , the closed air leading mechanism is additionally arranged on a liquid path above the infusion tube and capable of guiding purified atmosphere from an infusion bottle into a cavity of the infusion tube at the end of dripping in the same day, the manual pressure pump is additionally arranged on the infusion tube, and the container imitating type bottle rinsing drip apparatus is additionally arranged on the liquid incoming port. The disposable automatic streaming-stopping liquid-residue-prevention type blood transfusion apparatus has the advantages of capabilities of automatically stopping streaming when a previous infusion bottle stops dripping; blood coagulation and liquid path congestion possibly resulted from blood return in an infusion needle can be avoided; the closed type air leading mechanism can be used by nurses for preliminary starting and closing any time, thereby being safe and flexible and capable of transfusing valuable residual liquid in the blood transfusion apparatus in a blood transfusion bag into a human body; waste can be avoided and curative effect can be guaranteed; a patient can be rescued by pressurizing and rapid infusing; blood exposure accidents can also be avoided even the patient carrying the infusion bottle faints in a toilet. The disposable automatic streaming-stopping liquid-residue-prevention type blood transfusion apparatus is applicable to clinical continuous infusing and liquid residue prevention.

The invention discloses a monoclonal antibody of a blood coagulation factor IX. The antibody comprises a light chain and a heavy chain, wherein the variable region amino acid sequence of the light chain is represented by SEQ ID NO.3, and the variable region amino acid sequence of the heavy chain is represented by SEQ ID NO.4. The invention also discloses a preparation method of the antibody. The antibody can specifically identify the blood coagulation factor IX. The invention further discloses a method for purifying the blood coagulation factor IX from blood plasma through utilizing the antibody. The blood coagulation factor IX can be conveniently and efficiently purified from the blood plasma through utilizing the antibody, so the infection risks of the diseases comprising hepatitis A, the hepatitis B, AIDS and the like caused by the patient blood transfusion supplementation of the blood coagulation factor IX are reduced.

The invention discloses multi-parameter immunochromatographic assay test paper and a preparation method thereof. The multi-parameter immunochromatographic assay test paper comprises an immunochromatographic assay test paper lining plate, and is characterized in that a plurality of solid phase membranes, which are separated from each other, corresponding conjugate pad membranes, a sample pad membrane and an absorbent pad membrane are fixed on the immunochromatographic assay test paper lining plate, a test line reagent and a control line reagent are coated on the solid phase membranes which are separated from each other, and a colloidal particle reagent corresponding to needed detection indexes is arranged on the conjugate pad membranes. The immunochromatographic assay test paper for parallel tests by multiple parameters provided by the invention can be applied to the rapid and integrated detection analysis needed in clinic, food, medicines, chemical industry, environment, stock farming, agriculture and other aspects, and has the advantages that the limitation on production efficiency caused by existing single-parameter and multi-parameter immunochromatographic assay test paper preparation processes can be overcome, that the all performance of the test paper is not inferior to that of detection with a single detection index, that the separated detection of the multiple test indexes can be avoided when screening is implemented in physical examination, blood donation, blood transfusion and the like, that the operation is convenient and rapid, that the detection time is shortened, that the efficiency is improved, that the cost is lowered, that manpower and material resources are saved, and that the industrial production is easier.