117 results about "Blood temperature" patented technology

The present invention provides a method and apparatus for controlling the internal body temperature of a patient. According to the present invention, a catheter is inserted through an incision into a large blood vessel of a patient. By selectively heating or cooling a portion of the catheter lying within the blood vessel, heat may be transferred to or from blood flowing within the vessel and the patient's body temperature may thereby be increased or decreased as desired. The invention will find use in treating undesirable conditions of hypothermia and hyperthermia, or for inducing a condition of artificial hypothermia when desired.

The invention relates to a method and a system for determining the blood flow in an individual coronary artery of a patient, wherein the method comprises the steps of positioning a temperature sensor mounted at a distal portion of a guide wire at a distal position in the coronary artery, positioning an infusion catheter in the coronary artery such that the distal end of the infusion catheter is proximally of the temperature sensor, measuring the blood temperature with the temperature sensor, infusing cold indicator fluid with a known infusion rate and known or measurable temperature into the coronary artery by the infusion catheter, measuring the temperature of the mixture of blood and indicator fluid by the temperature sensor, and calculating the coronary blood flow by a formula based on the known and measured quantities. In an extended version, the method comprises steps for relating the calculated coronary flow value to related normal flow values, or related FFR values, or a related flow resistance.

An intro-aortic balloon catheter system and method for determining cardiac output with the system including a distal end for insertion into an aorta and a proximal end opposed to the distal end, a balloon portion in proximity to the distal end which repeatedly expands and contracts so as to assist the pumping action of the heart, a catheter tube connected to the balloon portion with the catheter tube having a lumen introducing a pressurized gas into the balloon portion and leading the pressurized gas out from the balloon portion and a temperature sensor attached to the catheter tube and being electrically coupled to a connector at the proximal end of the catheter tube. The method includes inserting the temperature sensor into a lumen of the intra aortic balloon catheter system, advancing the temperature sensor until it projects freely into the aorta, injecting an injectate of a temperature different to that of the temperature of the patient's blood into the central vein of the patient, measuring the blood temperature profile versus time by means of the temperature sensor and calculating cardiac output and optionally the derived variables from the measured temperature profile.

A waterless blood heater / cooler device directly controlling temperature of blood flowing through an extracorporeal blood circuit. A thermoelectric module is coupled to a supply voltage to generate a temperature difference. A heat exchanger cassette comprising a core and first and second laminar flow guides is in thermal contact (directly or indirectly) with the thermoelectric module. The cassette has a plurality of tubes for carrying parallel channels of the blood. The first and second laminar flow guides provide an inlet and an outlet for coupling to the extracorporeal blood circuit and respective intermediate chambers for receiving respective ends of the tubes in order to guide the blood to and from respective tubes in a substantially laminar flow.

A waterless blood heater / cooler device directly controlling temperature of blood flowing through an extracorporeal blood circuit. A thermoelectric module is coupled to a supply voltage to generate a temperature difference. A heat exchanger cassette comprising a core and first and second laminar flow guides is in thermal contact (directly or indirectly) with the thermoelectric module. The cassette has a plurality of tubes for carrying parallel channels of the blood. The first and second laminar flow guides provide an inlet and an outlet for coupling to the extracorporeal blood circuit and respective intermediate chambers for receiving respective ends of the tubes in order to guide the blood to and from respective tubes in a substantially laminar flow.

A catheter system for controlling the body temperature of a patient by modifying the temperature of blood flowing within a blood vessel of the patient. The catheter system comprises a catheter body having a heat exchange region in contact with the blood; and a mechanism for moving the heat exchange surface, thereby increasing heat exchange between the heat exchange surface and blood flowing past the heat exchange surface. Various methods of moving the heat exchange surface are disclosed.

An intralumenal implant material, which comprises, a polymer having a sol-gel transition temperature in an aqueous solution thereof, shows a substantial water-insolubility at a temperature higher than the sol-gel transition temperature, and shows a thermo-reversible water-solubility at a temperature lower than the sol-gel transition temperature. Such an intralumenal implant is capable to be endovascularly or percutaneuosly delivered into a vascular lumen in a liquid state at the temperature lower than the sol-gel transition temperature, is capable to be instantly converted into a gel state in the vascular lumen at the blood temperature higher than the sol-gel transition temperature and is capable of occluding aneurysms, vascular tumors or vascular malformation. Such intralumenal implant material shows excellent biocompatibility and mechanical matching for the vascular tissue and the surrounding tissue because it is a highly water-containing hydrogel. In addition, biologically active substances for promoting a prompt neo-endothelium formation and / or endothelialization can be easily incorporated into such an intralumenal implant material.

The invention relates to a method and a system for determining the blood flow in an individual coronary artery of a patient, wherein the method comprises the steps of positioning a temperature sensor mounted at a distal portion of a guide wire at a distal position in the coronary artery, positioning an infusion catheter in the coronary artery such that the distal end of the infusion catheter is proximally of the temperature sensor, measuring the blood temperature with the temperature sensor, infusing cold indicator fluid with a known infusion rate and known or measurable temperature into the coronary artery by the infusion catheter, measuring the temperature of the mixture of blood and indicator fluid by the temperature sensor, and calculating the coronary blood flow by a formula based on the known and measured quantities. In an extended version, the method comprises steps for relating the calculated coronary flow value to related normal flow values, or related FFR values, or a related flow resistance.

A blood pump control device based on physiological parameters relates to a control mode of a blood pump. The device comprises a multichannel data acquisition module and a data processing module, wherein the multichannel data acquisition module is arranged for acquiring a heart rate signal, a blood pressure signal before blood pumping, a blood pressure signal after blood pumping, a blood temperature signal, a blood pump outer surface temperature signal, a blood pump blade revolving speed signal, a blood pump voltage signal and a blood pump current signal and sending to the data processing module; the heart rate signal, the blood pressure signal before blood pumping, the blood pressure signal after blood pumping, the blood temperature signal and the blood pump outer surface temperature signal pass through an amplifying circuit, a filtering circuit and an A / D switching circuit in sequence; and the data processing module is arranged for receiving the signals from the multichannel data acquisition module, acquiring related signal values and then controlling the power of the blood pump according to the signal values by using a blood flow volume control algorithm. The blood flow volume can be regulated according to the measured physiological parameters so as to balance the blood pump output flow and the actual flow required by human body.

The implantable device is capable of performing thermal dilution analysis of the cardiac output of a patient using power delivered from an external source. By using power from an external source, the implantable device conserves its power resources for other purposes, such as for pacing or defibrillation therapy. In one example, an external programmer or bedside monitor provides power through a hand-held power delivery wand via electromagnetic induction, with the power routed from a subcutaneous coil to a heating element implanted in the right atrium, which heats blood as it passes through the right atrium. In another example, the heating element is formed of a material that generates heat in response to a beam of ultrasound provided by the wand. In either case, a downstream blood temperature profile is detected using a thermistor implanted in the pulmonary artery and cardiac output is then estimated by analyzing the temperature profile.

The blood temperature varying system based on distributed computer control consists of one extracorporeal blood circulation subsystem and one monitoring subsystem. The extracorporeal blood circulation subsystem includes a blood transfusion pipe, a heat exchanger, a water pump, an oxygenator, a post blood treater and a centrifugal pump. The monitoring subsystem includes a flow sensor, a heating / cooling device, a centrifugal pump rotation controller, a host control computer for precise temperature control, information display and data saving, and a multi-point temperature measuring instrument.

The invention provides a metabolism assessment system, which comprises a respiration monitoring module, a blood pressure and blood temperature monitoring module, a PH value measuring module, a living condition monitoring module, an impact factor monitoring module, an information processing module and a display module. The information processing module is in charge of continuously receiving, storing and transmitting information acquired by the respiration monitoring module and the impact factor monitoring module, calculating chest circumference and abdomen circumference differences of a sample between exhalation and inhalation under different impact factors, calculating a respiratory capacity within unit time in accordance with the chest circumference and abdomen circumference differences as well as a respiratory rate, and comparing the respiratory capacity with a preset threshold; and the information processing module, in combination with blood pressure, body temperature and PH value information, is used for analyzing work of respiratory dynamic performance and heart dynamic performance on blood circulation and lymphatic circulation, and for analyzing and assessing electromagnetic metabolism, chemical metabolism, mechanical metabolism and the like with the application of a correlation equation between the various impact factors. According to the comprehensive metabolism assessment system provided by the invention, human metabolism can be assessed by calculating the correlation equation on the basis of a big data technology.

Apparatus, computer system, computer program and storage medium for determining intrathoracic blood volume (ITBV) and other cardio-vascular parameters of a patient by thermodilution measurements. The apparatus comprises a) temperature influencing means (107) for provoking an initial local temperature change in the proximity of a first place (101) of a patient's vascular system (103), thus introducing a travelling temperature deviation to patient's blood stream, b) a temperature sensor device (117) for measuring the local temperature of patient's blood at a second place (102) of patient's vascular system (103) downstream of said first place (101) c) a computer system (104) coupled to said temperature sensor device (117) and adapted to record said patient's local blood temperature measured at said second place (102) as a function of time to determine a thermodilution curve, d) said computer system (104) being further adapted to determine patient's global enddiastolic blood volume (GEDV) and patient's intrathoracic thermovolume (ITTV) from said thermodilution curve, e) said computer system (104) being further adapted to determine patient's intrathoracic blood volume (ITBV) according to the following formula: ITBV=f(GEDV, ITTV, P), ITBV being the intrathoracic blood volume, GEDV being the global enddiastolic blood volume, ITTV being the intrathoracic thermovolume, P being an airway pressure inside patient's lungs. By determining ITBV not only from GEDV but also as a function of ITTV and P enhanced accuracy can be obtained, especially if the patient suffers from pulmonary edema and / or is mechanically ventilated.

Method for the continuous measurement of the glucose concentration in blood undergoing pulsational flow, with the steps: - determination of a value for the glucose concentration for a first measurement cycle, and - repetition of the determination of this value in subsequent measurement cycles, where there is multiple detection, within each measurement cycle, of the transmittance and / or scattering power of the blood for at least two incident NIR wavelengths, calculation of an indicator value depending on the blood glucose concentration, and ascertaining the blood glucose concentration by comparing the indicator value with a previously determined calibration table, determination of the blood temperature during the detection of the transmittance and / or scattering power, - continuous measurement of the pulse duration of the pulsational blood flow, where the duration of the measurement cycle is arranged to keep in step as integral multiple of the pulse duration, where the first of the at least two NIR wavelengths is selected from the wavelength range 1560-1630 nm, and the second of the at least two NIR wavelengths is selected from the wavelength range 790-815 nm, and the ratio of the transmittance and / or scattering power of the at least two wavelengths is calculated, this ratio serving in relation to the blood temperature as indicator value for reading off the blood glucose concentration from the calibration table.

The invention discloses a hollow fiber membrane oxygenator which is externally arranged on a heat exchange layer. The oxygenator comprises a housing and an upper end cover and a lower end cover detachably mounted on the housing. The housing includes an oxygenator housing, a hot water unit inner housing, an oxygenation unit housing and a core tube from the outside to the inside. The oxygenator shell and the hot water unit shell form a cavity of the hot water unit, the hot water unit shell and the oxygenation unit shell form a blood heat exchange cavity, and the oxygenation unit shell and the core pipe form a cavity of the oxygenation unit; The blood heat exchange chamber is communicated with the oxygenation unit through a circumferential opening. The hot water unit of the invention is arranged at the periphery of the oxygenation unit, so that not only the gas exchange efficiency can be improved, but also the temperature loss can be minimized to achieve the highest oxygenation efficiency. In addition, the temperature gradient of the oxygenator is very small, which can significantly reduce the probability of thrombosis in blood. At the same time, the blood temperature after oxygenation is close to the internal temperature of human body, which can bring better treatment experience.

This invention prevents the danger of falling of body temperature by making the blood temperature similar to the body temperature in the injection of Ringer's solution fluid or blood transfusion, and also alleviates the patient's pain and improves the speed at which Ringer's solution fluid or blood enters the body. The warming device is much cheaper than previously released products, and small and light in weight, and allows blood or solution fluids to flow most effectively by allowing sufficient time for heat transfer as a pack type. The operation is convenient and sanitary in its single usage only. The inventive purpose has the methods of utilizing the temperature sensor in adjusting temperature by utilizing them PTC heating element's resistance specialty against the temperature as well as temperature sensor.

The present invention provides a method and apparatus for controlling the internal body temperature of a patient. According to the present invention, a catheter is inserted through an incision into a large blood vessel of a patient. By selectively heating or cooling a portion of the catheter lying within the blood vessel, heat may be transferred to or from blood flowing within the vessel and the patient's body temperature may thereby be increased or decreased as desired. The invention will find use in treating undesirable conditions of hypothermia and hyperthermia, or for inducing a condition of artificial hypothermia when desired. The method and system further provide for the cooling of initially hypothermic patients whose blood or body temperature has been warmed above the desired target level and the warming of initially hyperthermic patients whose blood or body temperature has been cooled below the desired target temperature.

The invention relates to a ventricle auxiliary system based on a physiological signal, which belongs to the technical field of the biomedical engineering. The invention relates to a ventricle auxiliary system which comprises a controller, a driving module, a blood pump, a signal collecting module and a displaying module, wherein the driving module is in communication connection with the controller, the blood pump is controlled by the driving module, the signal collecting module is used for collecting the working state of the blood pump, processing the working state of the blood pump and transmitting the working state of the blood pump to the controller, and the displaying module is connected with the signal collecting module and the controller and can display the state of the blood and theinformation of the controller. The ventricle auxiliary system is characterized by also comparing a human physiology detecting system which is connected with the controller by the signal collecting module and can detect the physiological states of blood pressure, blood temperature, heart rate and blood flow of the human body, and the controller has six modes: a normal mode, a suction treating mode, a lung gore treating mode, a signal collecting module failure treating mode, a pulsating mode and a starting mode. The invention can regulate the working state of the blood pump on the basis of detecting the physiological state of patients to adapt to the physiological requirement of the patients.

The present invention relates to a device (30) and a related method for determining a blood gas partial pressure in blood in a circulatory system of a subject (12) of interest. Also a system for ventilating a patient is disclosed. Temperature-related measurement values indicative of given blood temperature levels are detected. Oxygen saturation measurements of the blood of said subject (12) under consideration of said temperature-related measurement values are derived. A blood gas partial pressure of a monitored subject (12) from said derived oxygen saturation measurements is determined under consideration of present blood temperature levels of said subject (12). Preferably, pH- representative values attributable to present blood pH-values of the subject (12) are determined. More preferably, the pH-representative values are derived from an oxygen dissociation curve under consideration of changes in said derived oxygen saturation measurements of the blood attributable to detected temperature-related measurement values of the subject's blood.

The present invention relates to a device (30) and a related method for determining a blood gas partial pressure in blood in a circulatory system of a subject (12) of interest. Also a system for ventilating a patient is disclosed. Temperature-related measurement values indicative of given blood temperature levels are detected. Oxygen saturation measurements of the blood of said subject (12) under consideration of said temperature-related measurement values are derived. A blood gas partial pressure of a monitored subject (12) from said derived oxygen saturation measurements is determined under consideration of present blood temperature levels of said subject (12). Preferably, pH-representative values attributable to present blood pH-values of the subject (12) are determined. More preferably, the pH-representative values are derived from an oxygen dissociation curve under consideration of changes in said derived oxygen saturation measurements of the blood attributable to detected temperature-related measurement values of the subject's blood.

The invention discloses a blood uniform mixing assisting device. The device comprises a main box. The upper side of the main box is provided with a display, viewing mirrors are arranged on the left and right sides of the main box, a support frame is installed in the main box, a telescopic shaft is installed at the lower side of the support frame, the lower end of the telescopic shaft is provided with mixing blades, a conveying plate is installed at the middle in the main box, the upper side of the conveying plate is provided with a rotating plate, the left side of the main box is provided with an indicator light, a pressing block is arranged below the indicator light, a compression spring is arranged at the lower side of the pressing block, and the left side of the pressing block is provided with a handle. The blood uniform mixing assisting device is provided with a heating plate so that a blood temperature in a blood bottle is guaranteed. A temperature sensor is arranged in the heating plate, can fast sense a temperature of the heating plate, can effectively prevent blood condensation and can prevent blood overheating. Through the pressing block and suction block design, after stirring, the blood bottle is conveyed to the heating plate. The suction block has a large suction force so that safe conveying of the blood bottle is effectively ensured.

Apparatus, computer system, computer program and storage medium for determining intrathoracic blood volume (ITBV) and other cardio-vascular parameters of a patient by thermodilution measurements. The apparatus includes: temperature influencing means for introducing a traveling temperature deviation to a patient's blood stream, a temperature sensor device for measuring the local temperature of the patient's blood downstream of the temperature influencing means, a computer system adapted to: record local blood temperature measured as a function of time to determine a thermodilution curve, determine global enddiastolic blood volume (GEDV) and intrathoracic thermovolume (ITTV) from the thermodilution curve, determine intrathoracic blood volume (ITBV) as a function of GEDV, ITTV and the airway pressure inside the patient's lungs (P). By determining ITBV not only from GEDV but also a function of ITTV and P enhanced accuracy can be obtained, especially if the patient suffers from pulmonary edema and / or is mechanically ventilated.

The invention relates to a rapid-temperature-controlled transfusion pump. The rapid-temperature-controlled transfusion pump is characterized in that a dripping chamber (1) is connected with an transfusion pump body (2) through an infusion pipe (9.1), the transfusion pump body (2) is connected with a heating inductor (3) through an infusion pipe (9.2), the heating inductor (3) is connected with a gas collecting device (4) through an infusion pipe (9.3), the middle of the infusion pipe (9.3) is provided with a temperature monitoring device (5), the infusion pipe below the gas collecting device (4) is provided with branches which are connected through a ping-pang safe stop valve (8), one branch is connected with an inner circulation loop (10), the other branch is connected with a patient loop (11), a bubble monitoring device (6) is installed between the infusion pipe below the gas collecting device (4) and the inner circulation loop (10), the patient loop (11) is provided with a pressure monitor (7), and a liquid medicine inflow pipe recognizing device (12) and an infrared temperature measuring point (13) are arranged above the dripping chamber (1). By means of the rapid-temperature-controlled transfusion pump, the real-time blood temperature ranging from 0 DEG C to 4 DEG C is raised to the temperature ranging from 36 DEG C and 40 DEG C, and fast infusion with the speed of 1000 ml / min is achieved; by means of a paramagnetic body, it can be ensured that the temperature of a heating body for transfusion does not exceed 42 DEG C, and the safety of blood products is guaranteed, necessary protection is achieved for the life safety of a patient; the rapid-temperature-controlled transfusion pump has the one-key emergency infusion function to meet the first-aid need.

The invention relates to medical instruments, in particular to a cooling device of an implantable heart assisting blood pump. The cooling device comprises a pump system and a driving system. The pumpsystem is provided with the blood pump and a pump case, and the driving system is provided with a stator and a rotor. The cooling device is characterized by further comprising heat directional conducting parts and vacuum heat insulating parts; the heat directional conducting parts are located on the periphery of the stator of the blood pump, and the vacuum heat insulating parts are located in thepump case of the blood pump. The heat directional conducting parts directionally conduct heat generated by the stator of the blood pump into blood. Outward radiation of the heat is reduced through thevacuum heat insulating parts, temperature rise of the surface of the blood pump is reduced, and heat damage to tissue is avoided. Meanwhile, as the specific heat capacity of the blood is very large and the heat dissipation function of the surface of the human body is very strong, the heat cannot cause increase the temperature of the blood. Vacuum is formed between the vacuum heat insulating layers, so that outward radiation of the heat is reduced. The problem of temperature rise of an implantable artificial heart-heart ventricle assisting system is effectively solved, and the temperature riseis completely within the human body physiological range after the implantable blood pump is implanted in the body.

The invention provides a blood irradiator. The blood irradiator comprises irradiation sources, a support, a cylindrical irradiation protection cover and a temperature regulating device, wherein the irradiation sources are mounted on the support, the irradiation protection cover wraps the irradiation sources and the support, and the temperature regulating device is used for regulating blood temperature. The irradiation sources mounted on the support are distributed in the inner wall of the irradiation protection cover uniformly, and irradiation light of all the irradiation sources is focused on a central axis of the irradiation protection cover. The outer wall of the irradiation protection cover is provided with a recessed blood tube mounting groove made of irradiation-light-transmitting materials, a blood tube is mounted in the mounting groove to coincide with the central axis of the irradiation protection cover, and two ends of the blood tube extend from two ends of the irradiation protection cover. By the aid of the technical scheme, since the outer wall of the irradiation protection cover is provided with the recessed blood tube mounting groove, the blood tube can be pushed in place from an opening of the mounting groove, and convenience in mounting is achieved.