The invention relates to a ventricle auxiliary system based on a physiological signal, which belongs to the technical field of the biomedical engineering. The invention relates to a ventricle auxiliary system which comprises a controller, a driving module, a blood pump, a signal collecting module and a displaying module, wherein the driving module is in communication connection with the controller, the blood pump is controlled by the driving module, the signal collecting module is used for collecting the working state of the blood pump, processing the working state of the blood pump and transmitting the working state of the blood pump to the controller, and the displaying module is connected with the signal collecting module and the controller and can display the state of the blood and theinformation of the controller. The ventricle auxiliary system is characterized by also comparing a human physiology detecting system which is connected with the controller by the signal collecting module and can detect the physiological states of blood pressure, blood temperature, heart rate and blood flow of the human body, and the controller has six modes: a normal mode, a suction treating mode, a lung gore treating mode, a signal collecting module failure treating mode, a pulsating mode and a starting mode. The invention can regulate the working state of the blood pump on the basis of detecting the physiological state of patients to adapt to the physiological requirement of the patients.