43results about How to "Minimal risk" patented technology

A system (and a method) for electronic financial transactions includes at least of each of a sender having an electronic wallet, a recipient having an electronic wallet, a sending bank having a host application system and an authentication server, a receiving bank having a host application system and an authentication server, and a wallet management center with a host application system and an authentication server. The sender uses its electronic wallet to send an encrypted payment instruction directly to the electronic wallet of the recipient. The recipient can accept the payment by performing a second level encryption of the payment instruction for submission to the wallet management center for authentication. Once authenticated, the wallet management center immediately notifies the recipient and submits payment instructions for clearing by the corresponding sending and receiving banks. Payment authorization is authenticated directly by the sending bank without involvement of the wallet management center.

An insufflating surgical instrument adapted for movement across an abdominal wall to insufflate an abdominal region of a patient is disclosed comprising a shaft having an insufflation channel extending along an axis between a proximal end and a distal end, the insufflation channel being adapted for connection to a source of fluid under pressure at the proximal end, a tip at the distal end of the shaft, and at least one vent hole formed at the tip or the shaft being in connection with the insufflation channel and being adapted to expel the fluid under pressure to insufflate the abdominal region. At least one of the tip and the shaft is formed of a translucent or transparent material such as polycarbonate to facilitate visualization of the abdominal wall and the abdominal region. The shaft includes a lumen extending along the axis between the proximal end and the distal end to enable insertion of a laparoscope. The lumen and insufflation channel may be formed as separate channels or as one shared channel. The tip may be blunt, the shaft and the tip may be integrally formed, and the vent hole may be of any geometric shape including round, oval, square and rectangular. The blunt tip may further comprise a marker to indicate penetration of the abdominal wall. In another aspect, the tip may be sharp, pointed or bladed to facilitate penetration of body tissue.

The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectably detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area.

The present invention relates to an apparatus and method for near-simultaneous and integrated delivery of bone graft material during the placement of surgical cages or other medical implants in a patient's spine. The integrated fusion cage and graft delivery device according to various embodiments delivers and disperses biologic material through a fusion cage to a disc space and, without withdrawal from the surgical site, may selectably detach the fusion cage for deposit to the same disc space. The integrated fusion cage and graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material and a fusion cage in or adjacent to the bone graft receiving area.

Systems and methods for distributing digital content from a service provider to users are described. In one aspect, a data partition scheme (methods and systems) is disclosed for a service provider to process and partition digital content into at least two parts: at least one enhancement part and at least one core part. The at least one enhancement part is much bigger than the at least one core part, but is of no or limited value to a user when the at least one core part is missing. The user can only reconstruct and play back the digital content when both the at least one enhancement part and the at least one core part is available. In another aspect, a distribution scheme (methods and systems) is disclosed to distribute the at least one enhancement part and the at least one core part over two separate systems: an enhancement part distribution sub-system built over a peer-to-peer network and a core part distribution sub-system built over a client-server network respectively. According to this scheme, a user acquires the at least one enhancement part through the enhancement distribution sub-system and the at least one core part through the core distribution sub-system, and assembly them to reconstruct and play back the digital content.

The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of human cytomegalovirus nucleic acid in a sample.

A remote cannulation assembly is disclosed for rapidly cannulating a body part such as a heart during a medical procedure. Cannulation is often conducted in procedures such as the installation of a ventricular assist device. The cannulation assembly of the invention utilizes an isolation valve to create a sealed fluid environment for the procedure. The invention further includes a coring assembly that may be used with the cannulation apparatus. Methods of cannulating a heart or other body part are also disclosed in which the risk of emboli is reduced. Additionally, methods of connecting and disconnecting two fluid conducting elements are disclosed.

The present invention is directed to a buprenorphine sustained release delivery system capable of delivering buprenorphine, a metabolite, or a prodrug thereof for a duration of about 14 days to about 3 months. The buprenorphine sustained release delivery system includes a flowable composition and a solid implant for the sustained release of buprenorphine, a metabolite, or a prodrug thereof. The implant is produced from the flowable composition. The buprenorphine sustained release delivery system provides in situ 1-month and 3-month release profiles characterized by an exceptionally high bioavailability and minimal risk of permanent tissue damage and typically no risk of muscle necrosis.

An unanchored 3-D portable archery target made of foam can withstand a 20 to 150-pound blow from an arrow without tipping completely over even though the target's weight (e.g., about 10 lbs.) is less than the arrow's force of impact. To achieve such surprising and unexpected results, the target employs a unique combination of weight, foam density, and a center of gravity that is counter-intuitively elevated to provide the target with a greater rotational moment of inertia. Although it would seem that an arrow with 800 in-lbs of kinetic energy should be capable of completely tipping over a target that requires only about 15 in-lbs of energy to tip over, the target's foam core has a density and gumminess that quickly dissipates most of the arrow's kinetic energy before the energy has time to tip the target over. A hollowed-out base underneath the target provides the target with greater stability.

This disclosure relates to a buprenorphine sustained release delivery system for treatment of conditions ameliorated by buprenorphine compounds. The sustained release delivery system includes a flowable composition containing a suspension of buprenorphine, a metabolite, or a prodrug thereof.

A method of removing a residual gas from inside a conventional shipping container is disclosed. The method first involves the step of accessing the container by opening a door of the container and fitting a panel to the open door space. Next the method involves extracting at least some of the residual gas present in the container via an outlet valve located at the panel using an external suction pump. Finally the method involves providing a flow of a flushing gas into the container via an inlet valve located at the panel to flush residual gas from the container. The total pressure of gases in the container can be monitored and controlled by adjusting the flow of gases in the inlet and outlet holes or valves.

An environmentally safe chemical dispensing system incorporates an enclosure containing structural elements including conveyance, containment, and control features which eliminate major sources of risk from spillage, and other sources of industrial chemical accident. The system is based upon an analysis of historical mishaps, and involves materials compatibility, functional utility, and practicability in a mechanical format involving a pump, and connection to a chemical source.

A process for safely excavating to reveal underground utilities. The process includes the steps of: identifying known utilities; planning an excavation trench; excavating the trench by: (i) making a cut of the excavation trench at a selected depth; (ii) extracting material from the trench; (iii) observing the trench; (iv) adjusting the depth of cut; and repeating (i) to (iv) until the process is complete.