36 results about "Alginate microspheres" patented technology

The invention provides an alginate microsphere encapsulating Bi2S3 nanoparticles and a preparation method thereof. The preparation method comprises the following steps: using a liquid-drop-type microfluidic technology, using sodium alginate aqueous solution containing a soluble sulfocompound as a dispersion phase, using an oil phase containing a surfactant as a continuous phase, forming a liquid drop in a microfluidic chip, importing the liquid drop into the aqueous solution containing Bi3<+> along with the continuous phase, and placing until a reaction is completed. The preparation method isbased on the liquid-drop-type microfluidic technology, and a sulfur source is provided by the sulfocompound in the dispersion phase. While the continuous phase is encountered in a microchannel, the dispersion phase is cut to the uniform liquid drops, and the liquid drops are imported to reception liquid containing the Bi3<+>, the in-situ formed alginate microsphere encapsulating Bi2S3 nanoparticles is obtained by one step. The process is simple, a particle diameter of the microsphere is controllable, and the obtained microsphere can be used as an intervention material. The microsphere has thefunctions of thermal therapy, embolism, CT imaging and sensibilization chemotherapy.

The invention discloses a developing embolic material and a preparation method of the developing embolic material. Developable barium-alginate embolic microspheres encapsulating in-situ synthesis barium sulfate particles are prepared from one step by the adoption of an electrostatic spraying technology, integration of a developing agent and the embolic material is achieved, and the problems that when interventional therapy is clinically adopted, indirect developing exists and rechecking is difficult are solved. The mono-dispersion microspheres with the grain diameter being 100-1000 microns can be obtained by adjusting and controlling the electrostatic spraying parameter, so that the mono-dispersion microspheres with the grain diameter being 100-1000 microns are suitable for embolism of vessels of different calibers. The development agent, barium sulfate, and the barium-alginate microspheres are formed at the same time, and the barium sulfate particles are evenly distributed in the microspheres and firmly fixed. Extracorporeal simulation experiments prove that the developing microspheres are quite stable within the testing time of 50 days. A big-eared rabbit right kidney arterial embolism experiment proves that the developing microspheres have a good developing effect and an embolic effect. Because the electrostatic spraying technology has the characteristics of being simple, rapid and low in cost, the one-step preparation method has the production potential.

The invention discloses a preparation method of a magnetic core-shell alginate microsphere adsorbent. The preparation method comprises the following steps: preparing two parts of sodium alginate solution, wherein one part is shell layer solution, and dichloromethane and nanometer ferroferric oxide are added into the other part and uniformly mixed to obtain nuclear layer solution; and respectively injecting the shell layer solution and the nuclear layer solution into the outer layer and the inner layer of a stainless steel coaxial needle head, jetting the shell layer solution and the nuclear layer solution into a receiving device filled with calcium chloride solution under high-pressure electrostatic jetting conditions by utilizing high-pressure electrostatic spinning equipment, stirring, filtering, then, immersing the microsphere in metal salt solution, stirring, filtering, and drying to prepare the magnetic core-shell alginate microsphere adsorbent. The magnetic core-shell alginate microsphere adsorbent has the adsorptive property of an alginate gel microsphere adsorbent to a part of anion and also has magnetic property; therefore, an adsorbing material is more convenient and rapid to recycle; the use recovery cost is reduced; the application range is enlarged; and the preparation method can be widely applied to anion adsorption concentration, settling separation and waste water treatment.

The invention discloses asiaticoside-chitosan-sodium alginate microspheres, a preparation method and application thereof, and belongs to the technical field of biomedical materials. The microspheres are prepared by an emulsification cross-linking method and finally obtained by freeze-drying. The preparation method comprises the following steps: 1) preparing sodium alginate solution and asiaticoside-chitosan acetic acid solution respectively; 2) slowly and uniformly adding sodium alginate solution to the oil phase, stirring at high speed to form colostrum; 3) ) Slowly and evenly add the asiaticoside-chitosan acetic acid solution to the colostrum, stir, and fully emulsify; 4) Slowly and evenly add the glyceraldehyde solution to cross-link and solidify, centrifuge, and the precipitate is washed with petroleum ether successively. washing, washing with absolute ethanol, and vacuum freeze-drying to obtain light yellow powder of asiaticoside-sodium alginate-chitosan microspheres.

The invention discloses an adsorption material based on modified sodium alginate microspheres and its preparation method and application. Sodium alginate and polyvinyl alcohol are dissolved in deionized water, and then added dropwise to a boric acid solution of calcium chloride Form gel balls in the medium; wash the gel balls and add them to the aqueous solution of silane coupling agent to react; disperse the reacted products in toluene, add 1,3-propane sultone to react; after the reaction , followed by washing with toluene, ethanol and deionized water, and drying to obtain the adsorption material of modified sodium alginate microspheres. The adsorption material of the modified sodium alginate microspheres provided by the present invention not only has a simple preparation process and low cost, but also has a stable structure, has good adsorption performance and recycling performance for cesium, and can be widely used in the synthesis of salt lake brine and geothermal water resources develop and use.

The invention relates to a method for preparing mono-dispersity calcium alginate microspheres based on emulsion liquid membrane mass transfer. The method includes the steps of firstly, preparing inner water phase, middle oil phase, outer water phase and collecting water phase fluid; secondly, respectively injecting inner water phase, middle oil phase and outer water phase fluid into the injection tube, the transition tube and the collecting tube of a microfluid device to form mono-dispersity water / oil / water emulsion, guiding the water / oil / water emulsion into the collecting water phase fluid, standing for at least 2 hours, allowing Ca<2+> in collecting water phase to enter inner water phase through the oil membrane mass transfer of water / oil / water double emulsion so as to have cross-linking reaction with sodium alginate to generate the calcium alginate gel microspheres, and allowing water in inner water phase to enter collecting water phase through oil membrane mass transfer; thirdly, using filter paper to filter collecting water phase solution containing the calcium alginate microspheres, and washing with deionized water to obtain the mono-dispersity calcium alginate microspheres.

The invention discloses a light-controlled slow-release pesticide preparation, which uses the photosensitive carrier europium alginate microspheres as the carrier, and uses the pesticide embedded and / or embedded in the carrier as the active ingredient; in the preparation, the pesticide used as the active ingredient The weight content is 5-95%; the preparation is in the form of porous nanoparticles with a particle diameter of 50-1000nm; the pesticide is a conventional chemical pesticide, or a bionic pesticide, a biological pesticide, or an insect pheromone. The present invention also provides a preparation method of the above light-controlled slow-release pesticide preparation.