60results about How to "Has antiviral activity" patented technology

A health-care additive of feed for promoting growth and taking care of health is prepared from 8 Chinese-medicinal material including haw, hot pepper, garlic, motherwort, etc through extracting in water and vinegar.

The invention discloses a porcine alpha interferon gene and a synthetic method thereof. The gene provided by the invention has the advantages that the high expression of the interferon in pichia pastoris is realized; porcine alpha interferon protein with antiviral activity is acquired; the anti-VSV activity of the porcine alpha interferon gene prepared from the synthetic method is (3.82*107) U / mg. The synthetic method designs the coding nucleotide sequence of the porcine alpha interferon on the basis that the amino acid sequence of the porcine alpha interferon is not changed; each codon in a reading frame is preferred by pichia pastoris; the coding nucleic acid is designed in the synthetic steps; a proper expression vector is inserted in the synthetic nucleic acid to build recombinant expression vector; finally the built recombinant expression vector converts proper pichia pastoris for inducible expression; the result shows the high expression of the porcine alpha interferon in the pichia pastoris, and the porcine alpha interferon protein with antiviral activity is acquired; the synthetic method is suitable for the synthesis of the porcine alpha interferon.

The invention specifically relates to a preparation method for a selenium-rich hair weed product, which belongs to the technical field of food bio-concentration. According to the invention, hair weed cells transforms the inorganic selenium--sodium selenite in a nutrient solution into organic selenium in virtue of the own transformation effect of the cells, so harm to the human body is reduced, and absorption and utilization of selenium by human beings and animals are improved; and the growth rate of the hair weed cells in the process of culture is 30 times of the growth rate of cells of wild hair weed, so rapid growth and reproduction of hair weed are realized. The hair weed cells produced in the invention can be used as a natural biological raw material for selenium supplement and are extensively applied to a variety of health food, beverages and new resource food to meet demands of the human body for selenium. The nutrient solution deprived of the hair weed cells contains abundant hair weed exopolysaccharide which has antiviral activity and can replace hair weed as a raw material for production of functional food. A hair weed selenium enrichment culture method provided by the invention is simple and convenient to operate, poses no pollution to the environment, has low cost and is applicable to industrialized production.

The invention discloses a handmade calligraphy paper using crofton weed root powder as the new filling material and a preparation method thereof. The handmade calligraphy paper is made of edgeworthia gardneri bark and crofton weed root, and is prepared through the following steps: (1) preparing crofton weed root powder: preparing a proper amount of crofton weed root, soaking, steaming and boiling, drying in air, cutting, grinding, and finally sieving so as to obtain the crofton weed root powder; (2) preparing edgeworthia gardneri pulp: weighing edgeworthia gardneri according to a certain weight ratio, and making the weighed edgeworthia gardneri into pulp through a traditional handmade paper technology; (3) pulping and paper making: mixing the prepared crofton weed root powder and edgeworthia gardneri pulp, then pulping, and finally producing paper through a conventional handmade paper manufacturing method. The prepared handwork calligraphy paper has the advantages of special texture, good ink absorbing performance, and mothproof effect.

The invention relates to compound echinacea extract powder capable of improving animal disease resistance. The compound echinacea extract powder is prepared from the following components in parts by weight: 60-75 parts of echinacea extract, 5-15 parts of lipase, 5-15 parts of glucose oxidase and 5-15 parts of bacillus subtilis. The compound echinacea extract powder can resist virus, enhance animalimmunity, and greatly reduce the illness probability of animals, meanwhile, the components are simple, preparation is convenient, and the compound echinacea extract powder can be suitable for multiple kinds of animals, and has very wide applicability.

The invention discloses a use of rimantadine Schiff base. Rimantadine ethylamine Schiff base was prepared by chlorination of adamantane formic acid with thionyl chloride, alkylation in the presence oftrimethyl aluminum and cerium formate, oximation to ketoxime, reduction with palladium-carbon and aldehyde-amine condensation reaction with cinnamaldehyde to obtain adamantane ethylamine cinnamaldehyde Schiff base. The reaction route of the invention changes the route of synthesizing adamantane methyl ketone, and cerium formate is used for assisting the reaction of trimethyl aluminum, so that thereaction conditions are mild and the by-products are few. The synthesis method has the advantages of simple and feasible process, low catalyst consumption, environmental protection and high product yield. The adamantine Schiff base prepared by the invention has antibacterial activity, antiviral activity and antitumor activity, and can be used in the fields of medicine, daily chemistry, food and the like, and has the potential to be used as an antibacterial agent, an antiviral agent and an antineoplastic agent.

An anti-HSV agent that inhibits the replication of HSV-1 and HSV-2 that is derived from a plant. Further, provided is a method of producing a potassium hydroxide extract of pine cone having anti-HSV activity, and the anti-HSV agent.

The invention discloses a synergistic chemical and photodynamic antibacterial and antiviral coating and a preparation method thereof, comprising the following steps: S1, dissolving soluble metal salts, phthalocyanine compounds, and dopamine hydrochloride in a mixed solvent, and reacting to obtain metal ions- Phthalocyanine / dopamine coordination complex, then add Tris solution, adjust the pH of the solution to 7.5-10.0 with dilute acid; S2, atomize and spray the reaction solution onto the surface of the substrate, irradiate with sunlight or xenon lamp for a period of time, the substrate Wash the surface alternately with water and ethanol, and dry it. According to the coordination effect of catechol, copper ion and zinc ion, the adhesion of dopamine oxidation film to the substrate is used, and the active oxygen clusters generated by phthalocyanine exposed to light are used to promote the oxidative self-polymerization of dopamine on the surface. Immobilizing metal ions with antibacterial and antiviral activity and phthalocyanine compound with photodynamic antibacterial activity on the surface of the substrate has universal applicability to most substrates, simple method and easy operation, and solves the problems existing in the prior art.

The invention discloses a porcine SAMHD1 gene, which comprises a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO.1. The invention also discloses the porcine SAMHD1 protein, which has the amino acid sequence shown in SEQ ID NO.1. The invention also discloses a monoclonal antibody against porcine SAMHD1 protein. The porcine SAMHD1 gene and protein of the invention have antiviral activity, are suitable for developing antiviral drugs, and have broad application prospects. The monoclonal antibody of the invention has good specific reaction with porcine SAMHD1 protein, and lays an important foundation for further research on the biological function of porcine SAMHD1 protein.