Anti-hsv agent for inhibiting replication of HSV-1 and HSV-2 and method of producing a substance having anti-HSV activity
A technology of -HSV, active ingredients, applied in the field of anti-HSV drugs, can solve the problem of epithelial replication not establishing latent infection and so on
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[0032] Plants have been a major source of medicinal compounds for thousands of years. Currently, chemical constituents and analogs derived from plant materials account for a major part of clinically used drugs. One such plant product is derived from the cones of various pine trees. Any commercially available pine cone raw material can be used to prepare anti-HSV substances. The substance, having a defined degree of activity, can be extracted from pine cones using an aqueous KOH base solution. The substances contained in the extract and used as active ingredients are high molecular weight substances. The most potent substances are named PCC or PCE.
[0033] The extraction solution should be concentrated to the desired concentration, neutralized, if necessary, with an appropriate acid, and then freeze-dried to form a solution or solid of the appropriate concentration. The product was used as active ingredient without further fractional purification. Refrigerate material not...
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