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58results about How to "Good obedience" patented technology
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Bio-medical porous titanium products and preparation method thereof
InactiveCN101418392AReduce stress concentration effectsGood obedienceSurgeryProsthesisPowder metallurgyArtificial joints
The invention relates to a biological medical porous titanium material and a preparation method thereof. The preparation method, namely a method adopting powder metallurgy, is to add spherical particles of novel polymethyl methacrylate pore-forming agent to prepare a structure provided with a rough surface and three-dimensionally communicated open pores, wherein the number, the shape and the size of the pores can be controlled, namely, the porosity degree is less than 70vol. percent, the open porosity factor is more than 60 percent, the average pore diameter is less than 500 mums, the Young's modulus in compression is more than 0.3 GPa, the compressive strength is more than 40MPa, and the bending strength is more than 50MPa. The biological medical porous titanium material can be widely applied in the field of biological medical implants such as dental implants, artificial joints, spinal orthopaedic internal fixed systems, medullary internal nails and orthopaedic armor plates.
Owner:DALIAN JIAOTONG UNIVERSITY
Flexible direct-drive type steering rack
ActiveCN102963388AReduce manufacturing costHigh transmission efficiencyElectric motor propulsion transmissionRailway transportThin layerCritical speed
The invention relates to a flexible direct-drive type steering rack, which uses a flexible beam to enable a structure to be flexible. Left and right lateral racks easily do relative nodding movement, so as to be applicable to a triangular pit with a larger rail. The structure is flexible so that a series of suspension can be simplified to a very thin layer of rubber cushion, and the production cost is reduced; an elasticity transmission device is elastically suspended through a permanent magnet motor, so that the torque can be transmitted, the transmission efficiency can be improved, and the weight of a transmission mechanism can be reduced; a traction force and a braking force can be directly transmitted to a car body instead of the structure of the steering rack, and the stress condition of the structure of the steering rack is optimized; meanwhile, the length of a traction rod is not limited by the structure, so that the traction rod can be longer, the secondary addition rigidity brought by the traction rod can be reduced, and the riding comfort degree of a vehicle can be improved. A motor is suspended between wheel pairs, so that a shaft distance can be reduced. Therefore, the steering rack not only can have higher critical speed through a smaller curve, but also has good submissiveness on route irregularity.
Owner:CRRC NANJING PUZHEN CO LTD
Direct-driving type bogie structure
ActiveCN102963387AImprove ride comfort performanceReduce weightBogiesBogie-underframe connectionsBogieStress conditions
The invention relates to a direct-driving type bogie structure. A permanent magnetic motor is elastically suspended by an elastic driving device, so that torque can be transferred, the transmission efficiency is improved, the weight of a driving mechanism is reduced; and traction force and braking force are directly transmitted to a vehicle body and are not transmitted through a bogie frame, so that the stressing condition of the a bogie frame is optimized, the length of a traction pull rod is not limited by the bogie frame structure, the traction pull rod can be longer, diallel additional rigidity caused by the traction pull rod is reduced, and the taking comfort of a vehicle is improved. The motor is suspended between wheel pairs, so that the axle distance is reduced, the bogie can pass a shorter curve, has higher critical speed, and has good submissiveness to unevenness of a road.
Owner:CRRC NANJING PUZHEN CO LTD
Particles for delivery of active ingredients, process of making and compositions thereof
InactiveCN101500937ANon-irritatingEasy to usePowder deliveryNanostructure manufactureMedicineNanoparticle
Owner:PANACEA BIOTEC
Novel method for preparing menstrual blood mesenchymal stem cells
ActiveCN104711220AGood obedienceSo as not to damageSkeletal/connective tissue cellsHigh cellCell activity
The invention relates to a novel method for preparing menstrual blood mesenchymal stem cells. The method comprises the following steps: a, collecting menstrual blood in vitro, and storing in menstrual blood collecting liquid to obtain menstrual blood mixed liquid; b, separating single karyocyte from the menstrual blood mixed liquid; C, culturing the single karyocyte in an adherent manner, proliferating cells, and then through adherent purification, obtaining purified cells, namely the menstrual blood mesenchymal stem cells. The novel method has the advantages of being nondestructive in the body, strong in uniformity and high in cell activity which is reflected in the characteristics of high cell proliferation speed, high passage times and the like.
Owner:ZHEJIANG SHENGCHUANG PRECISION MEDICAL TECH CO LTD
Preparation method and use method of biologically degradable shape memory tubular support stent
The invention discloses a preparation method and a use method of biologically degradable shape memory tubular support stent, wherein the steps of the preparation method comprises physical blending technology, in which the vitrification point of at least one component is below 37 DEG C and that of at least one component is beyond 37 DEG C, or chemical copolymerizing technology, in which two monomers are chemically polymerized to form degradable shape memory high polymer material composed of chain segment 1 and chain segment 2; the vitrification point of the chain segment 1 is below 37 DEG C; and the vitrification point of the chain segment 2 is beyond 37 DEG C; according to FOX formulation, the mass ratio of each polymer in physical blending technology is calculated, and the mass ratio of two monomers in chemical blending technology is also calculated, thereby ensuring that the prepared stent can recover to memorized shape at 37 DEG C of body temperature; therefore, the stent can recover to memorized shape naturally without external heating if the stent is implanted into human body; the stent is featured with convenient operation, high compliance of patients, easy preparation, no toxic matter introduced, high biocompatibility and safety.
Owner:SOUTHWEST JIAOTONG UNIV
Self-heating medical ultrasonic coupling agent device with sterilization and disinfection effects and preparation thereof
ActiveCN101718465AReduce cross infectionAvoid cold stimulationUltrasonic/sonic/infrasonic diagnosticsSurgeryHuman bodyUltrasonography
The invention relates to a self-heating medical ultrasonic coupling agent device with sterilization and disinfection effects and a preparation method thereof. The medical ultrasonic coupling agent device comprises an outer shell. The inside of the outer shell is provided with a coupling agent cavity and a self-heating cavity which are not communicated with each other. The self-heating cavity is filled with a disposable self-heating agent. The coupling agent cavity is filled with a medical ultrasonic coupling agent with sterilization and disinfection effects. The medical ultrasonic coupling agent device utilizes the automatic heating effect of the self-heating agent to perform conduction heating on the medical ultrasonic coupling agent to make the temperature of the medical ultrasonic coupling agent reach about the temperature of the human body surface so that the patient never feels the cold stimulation of the coupling agent when being subjected to the B-ultrasound examination. Moreover, the medical coupling agent has the rapid and efficient sterilization and disinfection effects, guarantees to effectively disinfect an ultrasonic probe and prevent the cross infection in the hospital, has the retention sterilization effect on the skin or the mucosa of the examined region, has simple preparation process and saves investment and cost.
Owner:武汉耦合医学科技有限责任公司
Resveratrol micelle eye drops and preparation method thereof
InactiveCN105125491AGood solubilityMicellar particle size is smallSenses disorderHydroxy compound active ingredientsDrug actionPatient compliance
Owner:滨州医学院烟台附属医院
Method for preparing hollow fiber multiporous biological titanium material
A preparation method of hollow fiber multihole biologic titanium material belongs to biotechnology field. The invention includes steps: (1) wrapping titanium or titanium alloy fiber on a compact core rod, shaping; (2) putting the core rod wrapped with titanium or titanium alloy fiber in a mould, compacting by a hollow pressure head having inner diameter equal to diameter of the compact core rod, keeping load under load pressure, removing the mould and the core rod to get hollow multihole rods or columns with required length and porosity; (3) putting multihole titanium rods or columns compacted as body, sintering in vacuum or argon atmosphere to get hollow fiber multihole biologic titanium material. The method of this invention is simple, can get slim hollow fiber multihole biologic titanium material having optional ratio of length and diameter, fibre distribute uniformly, surface is flatten via shaping; good controllability of central cavity size, aperture and porosity, simple preparation method, fast speed, high rate of finished products, low cost.
Owner:SHANGHAI JIAO TONG UNIV
S-adenosylmethionine formulations with enhanced bioavailability
InactiveCN102695514AGood obedienceImprove side effect performanceOrganic active ingredientsNervous disorderImmunologic disordersS-Adenosyl-l-methionine
The invention relates to compositions and methods to enhance the absorption of S- adenosylmethionine (SAMe) and to methods of treating various disorders or diseases using non-parenteral SAMe formulations with enhanced-absorption and improved bioavailability. The enhanced bioavailability formulations may be used to treat a variety of diseases or disorders, such as for example, psychiatric disorders including, generalized anxiety disorder, obsessive compulsive disorder, post traumatic stress disorder, panic disorder, depressive disorders (e.g. major clinical depression) and dysthymia; as well as treating liver disorders, cancer, autoimmune disorders, inflammatory disorders, joint disorders, gastrointestinal disorders and cardiovascular disease.
Owner:MSI METHYLATION SCI
Curcumin micelle eye drop and preparation method thereof
ActiveCN105030669AImprove solubilitySmall particle sizeSenses disorderMetabolism disorderPolythylene glycolPharmaceutical Aids
The invention discloses a curcumin micelle eye drop. The eye drop comprises curcumin as a main drug, an antiseptic, an isotonic regulator, and also comprises a polyethylene caprolactam-polyvinyl acetate-polyethylene glycol copolymer as a drug adjuvant, and dequalinium chloride as a mitochondrial targeting modifier and a stabilizer, a mass ratio of the curcumin main drug to the polyethylene caprolactam-polyvinyl acetate-polyethylene glycol block copolymer drug adjuvant is 1:12-1:20, and a mass ratio of dequalinium chloride to the polyethylene caprolactam-polyvinyl acetate-polyethylene glycol copolymer drug adjuvant is 1:20-1:40. The administration concentration of the curcumin micelle eye drop prepared in the invention can reach 5mg / ml, and the eye drop has the advantages of small micelle particle size, uniform distribution range, good drug stability, reduction of the administration irritation, improvement of the drug absorption of cornea, reduction of the administration concentration, prolongation of the action time of the drug, reduction of the administration frequency, improvement of the patient compliance, and very good economy.
Owner:SHANDONG EYE INST
Bidirectional driving ankle rehabilitation training exoskeleton
PendingCN109091816AImprove biomimicryRestore walking functionProgramme-controlled manipulatorMuscle exercising devicesExoskeleton robotAnkle rehabilitation
The invention relates to the field of rehabilitation exoskeleton robots, in particular to a bidirectional driving ankle rehabilitation training exoskeleton, which has the advantages of simple structure, high bionic performance, easy driving, good movement effect and the like, can effectively help a wearer to carry out ankle rehabilitation training, can be easily mounted on the lower limb foot andthe lower leg part of the wearer through a foot sleeve and a calf sleeve, can carry out bidirectional driving through a first driving device and a second driving device on both sides of the calf sleeve, and provides two activities of plantar flexion and dorsiflexion of the foot for the wearer during walking, so that the power consumption of calf muscles of the wearer during walking is greatly reduced to assist the wearer in rehabilitation training, and the ankle walking function is recovered as soon as possible; and meanwhile, the first driving device and the second driving device carry out bidirectional driving ankle rehabilitation training, and the exoskeleton mechanism has high bionic performance, the walking process of the human body is optimized, and the compliance between the wearerand an orthosis robot.
Owner:JIANGSU JICUI MICRO NANO AUTOMATION SYST & EQUIP TECH RES INST CO LTD
Hollowed-out membrane used as hernia patch and preparation method thereof
The invention discloses a hollowed-out membrane used as a hernia patch and a preparation method thereof. The hollowed-out membrane used as the hernia patch is a high-polymer membrane with holes, and the high-polymer membrane with the holes is used as the hernia patch; and the thickness of the high-polymer membrane is 0.05 to 1.0 millimeter. The preparation method comprises the following steps of: (1) preparing a high-polymer material into a primary membrane by a melting casting method; (2) performing two-way stretching on the primary membrane; (3) punching the holes in the surface of the membrane by a machine carving method; and (4) flattening and performing heat setting to obtain the hollowed-out membrane used as the hernia patch. The hollowed-out membrane has high mechanical property and biocompatibility. And the method for preparing the single-layer hollowed-out membrane for the hernia patch is simple and is suitable for industrial production.
Owner:DONGHUA UNIV
Hand intended for being provided on a humanoid robot with improved fingers
ActiveCN106132640AGood obedienceProgramme-controlled manipulatorGripping headsRotational freedomEngineering
The invention relates to a hand intended for being provided on a humanoid robot. The hand comprises a palm and at least one finger (14) articulated to the palm, the finger (14) comprising at least one phalanx (21, 22, 23) and an articulation (27, 28, 29) connecting the phalanx (21, 22, 23) to the palm, the phalanx (21, 22, 23) extending in a main direction (31, 32, 33). According to the invention, the articulation (27, 28, 29) comprises a resilient joining part (35, 36, 37) that allows several degrees of freedom. The hand comprises motorisation means (50, 51) for motorising one degree of rotational freedom among the degrees of freedom made possible by the joining part (35, 36, 37), the motorised degree of rotational freedom allowing a relative movement about a shaft (41, 42, 43) perpendicular to the main direction (31, 32, 33) of the phalanx (21, 22, 23). The other degrees of freedom among the degrees of freedom made possible by the joining part (35, 36, 37) are not motorised.
Owner:ALDEBARAN ROBOTICS SA
Medical purpose of NMDA acceptor antagonist and pharmaceutical composition thereof
InactiveCN105327349AEasy accessImprove bioavailabilityPowder deliveryOrganic active ingredientsNR1 NMDA receptorDisease
The invention discloses a medical purpose of an NMDA acceptor antagonist and a pharmaceutical composition thereof. The invention concretely discloses a medicine for using the NMDA acceptor antagonist, a pharmaceutically acceptable salt or a pharmaceutical composition thereof for treating or preventing central nervous system disease and / or mental diseases, and the NMDA acceptor antagonist is delivered to a human central nervous system through target administration. An application of the pharmaceutical composition can increase the concentration of the NMDA acceptor antagonist in brain tissue, medicine amount is greatly reduced, and systematic side effect is reduced; biology availability in the brain is high, autonomous drug administration can be carried out by patients, no pain is generated, usage is convenient, and thus the pharmaceutical composition has good patient compliance, and has wide clinical medical science application.
Owner:SHANGHAI HANSOH BIOMEDICAL
Method and system for detecting COVID-2019 pneumonia
PendingCN111413492AGood obedienceLow costBiological testingNeural architecturesHuman bodyNucleic acid detection
The invention provides a method and a system for detecting COVID-2019 pneumonia, which belongs to the technical field of biomedicine and data processing. Expiratory NO concentration detection is carried out on a non-new coronal pneumonia patient, statistics of basic human body characteristic information is carried out, a mathematical model between the expiratory NO concentration and the basic characteristics of the human body is established, expiratory NO data of the suspected new coronal pneumonia patient are analyzed by using the mathematical model, whether a subject is sick or not is thus judged, the problem of discomfort of a human body caused by traditional nucleic acid detection sampling is effectively solved, and the method has the advantages of low cost, rapidness, no damage and the like, causes no pain to the subject, is good in compliance, is particularly suitable for being applied to large-scale preliminary screening work of suspected COVID-19 patients, and has good practical application value.
Owner:SHANDONG UNIV
Aerosol for treating bedsore and preparation method of aerosol
ActiveCN104586899AIncrease nutritionBroad spectrum antibacterialOrganic active ingredientsPeptide/protein ingredientsBULK ACTIVE INGREDIENTWater soluble chitosan
The invention relates to an aerosol for treating bedsore and a preparation method of the aerosol, and belongs to the technical field of a medical aerosol. The aerosol consists of the following components: antibacterial peptide, water-soluble chitosan, a synergist, a stabilizer, a propellant and the balance of purified water. The preparation method comprises the following steps: respectively preparing an antibacterial peptide solution and a chitosan solution, sequentially adding equivalent synergist and stabilizer to the two solutions, and then uniformly mixing the two solutions to obtain a medicine liquid, filling and sealing the medicine liquid, injecting the propellant and pressing an aerosol cover so as to obtain a finished product. Through a synergistic effect generated from the combination of the antibacterial peptide and the water-soluble chitosan, the aerosol disclosed by the invention is not only strong in antibacterial and anti-inflammatory properties, but also capable of accelerating and promoting the healing of a wound surface and quite excellent in effect of clinically treating bedsore; by virtue of the sprayed chitosan solution, a film can be rapidly formed on the surface of skin so as to effectively protect the wound surface and reduce inflection risk; and the film is degradable and absorbable, and is safe, clean and convenient; and the aerosol is stable in active ingredient, long in drug action time, free from frequent administration and good in compliance.
Owner:GUANGDONG OCEAN UNIVERSITY
Dex-ibuprofen injectable suspension and preparation method thereof
The invention discloses a dex-ibuprofen injectable suspension and a preparation method thereof. The preparation consists of dex-ibuprofen, low-acyl gellan gum, carrageenan, pectin and a colloidal property reinforcing agent. The dex-ibuprofen injectable suspension prepared with the method is a thixotropic liquid, and has the characteristics of low viscosity, high suspension supporting property and permanent lamination resistance, so that the sizes of dex-ibuprofen particles can be kept stable during long-term storage.
Owner:陆荣政
Dry suspensoid of Repirinast and its prepn. method
ActiveCN1903176AGood dispersionEvenly distributedPowder deliveryOrganic active ingredientsRepirinastLubricant
A mixed dry suspension of repirinast is proportionally prepared from repirinast, suspending aid, filler, flavouring and lubricant. Its preparing process is also disclosed.
Owner:JUMPCAN PHARMA GRP
Bitterness covering agent for Chinese medicine mixture
ActiveCN103520471AImprove matchGood obedienceAntibacterial agentsSolution deliveryRehmannia glutinosaRadix Ophiopogonis
Owner:HAINAN HONZ PHARMA +2
Ganoderma lucidum liquid fermentate, composition containing the fermentate , preparation method and application of the same
ActiveCN101172125BAnti-fatigueEnhance body vitalityFungiImmunological disordersVitalityPolysaccharide
Owner:四川省中医药研究院
Limonene drop pills oral medicine for treating biliary passage disease and its preparation process
InactiveCN1803127AImprove stabilityGood obedienceOrganic active ingredientsDigestive systemDiseaseOral medicine
The invention discloses a limonene medicinal drop pill for treating biliary tract diseases, wherein the existing dosage types for the conventional limonene preparations are modified to obtain drop pills with the advantages of simple process for manufacturing, shorter disintegration time, quicker action, better pharmaceutical stability, and longer effective period.
Owner:成都和康药业有限责任公司
Dexibuprofen suspension composition and preparation method thereof
InactiveCN106176596ASame sizeGood dispersionOrganic active ingredientsAntipyreticGellan gumCarrageenan
The invention discloses dexibuprofen suspension and a preparation method thereof. The preparation comprises dexibuprofen, low acyl gellan gum, carrageenan, pectin and a colloidality enhancer. The dexibuprofen suspension prepared by adopting the method is a thixotropic liquid, has the characteristics of low viscosity, high suspending property and no layering forever and has the beneficial effect that the particle size of dexibuprofen can remain stable in long-term storage.
Owner:SHANGHAI YANAN PHARM
Insulin analog complex with reduced affinity for insulin receptor and use thereof
ActiveCN110536899AGood obediencePeptide/protein ingredientsMetabolism disorderPancreatic hormoneInsulin proreceptor
Owner:HANMI PHARMA
Self-heating medical ultrasonic coupling agent device with sterilization and disinfection effects and preparation thereof
ActiveCN101718465BReduce cross infectionAvoid cold stimulationUltrasonic/sonic/infrasonic diagnosticsSurgeryHuman bodyUltrasonography
Owner:武汉耦合医学科技有限责任公司
Traditional Chinese medicine powder for treating skin pruritus and application thereof
ActiveCN105770656ADry alkalinePlay a neutral rolePowder deliveryAntimycoticsEczematous rashSkin Pruritus
The invention relates to traditional Chinese medicine powder for treating skin pruritus and application thereof. The traditional Chinese medicine powder comprises, by weight, 30-60 parts of stove ash, 10-30 parts of radix sophorae flavescentis, 10-30 parts of fructus cnidii, 10-30 parts of radix stemonae, 2-5 parts of borneol, 2-5 parts of menthol and 5-10 parts of borax. The traditional Chinese medicine powder is suitable for being used to treat eczema, beriberi, tinea cruris, scrotal eczema and pruritus vulvae. The traditional Chinese medicine powder has effects of improving the microenvironments of the affected parts of a patient and inhibiting bacteria and is capable of promoting the recovery of skin functions, good in curative effect and high in cure rate.
Owner:吴少鑫
External traditional Chinese medicine composition ointment, preparation method, use method and application
InactiveCN105998477AEasy to collectLow costAerosol deliveryDigestive systemEvodia rutaecarpaCombined treatment
The invention relates to external traditional Chinese medicine composition ointment which is prepared from the following traditional Chinese medicines in parts by weight: 3-7 parts of evodia rutaecarpa, 2-5 parts of raw rhubarb, 2-5 parts of rhizoma picrorhizae, 3-7 parts of arisaema cum bile and 1-2 parts of radix cyathulae. The preparation method comprises the following steps: respectively cleaning the traditional Chinese medicines with clear water, then drying the traditional Chinese medicines, respectively grinding the traditional Chinese medicines with a traditional Chinese medicine grinder at normal temperature (25 DEG C) under aseptic and dustless conditions, sieving the powder with a 100-mesh sieve, uniformly mixing the powder proportionally, and then blending the mixture with mature vinegar to obtain the ointment. The external traditional Chinese medicine composition ointment is externally applied to the Yongquan acupoint; according to the traditional Chinese medicine dialectical principle of pediatric head and face fever, the ointment takes the prescription principles of inducing heat downward, clearing away the stomach-heat and purging the pathogenic fire, ensuring proper downward flow of the blood, guiding fire to origin and the like; and thus, an overall comprehensive treatment method of dialectical therapy is realized.
Owner:聂峰
Citrate-sugar alcohol solution used for aerosol inhalation
PendingCN111297836AInhibitory reactivityImprove clearanceOrganic active ingredientsDispersion deliveryArabitolGalactitol
Owner:BEIJING BEIPENG SCI & TECH
Graphite/elastic resin composite grains, preparation method thereof and application of graphite/elastic resin composite grains to manufacturing of polishing wheel
ActiveCN109810485AImprove friction resistanceImprove cooling effectAbrasion apparatusGrinding devicesPolymer sciencePolyester resin
The invention relates to graphite / elastic resin composite grains, a preparation method thereof and application of the graphite / elastic resin composite grains to manufacturing of a polishing wheel. Thepolishing wheel is prepared from unsaturated polyester resin, abrasives, a filler and the graphite / elastic resin composite grains, wherein the graphite / elastic resin composite grains are prepared from the following components in percentage by volume: 30-70 vol% of graphite and 30-70 vol% of elastic resin, and the grain size of the composite grains is 200-1500 [mu]m. The graphite / elastic resin composite grains are applied to preparation of the resin polishing wheel, the obtained resin polishing wheel is excellent in friction resistance, lubricating performance and heat-dissipation performance,the processing quality is improved, the service life is prolonged, and the problem of poor lubricating and heat-dissipation effects during machining of the resin polishing wheel are solved.
Owner:天津佐源新材料科技有限公司
Multifunctional burn cream and preparation method thereof
InactiveCN113041301ANon-irritatingControl wound infectionAerosol deliveryOintment deliveryRheum officinaleCoptis chinensis
The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a multifunctional burn cream and a preparation method thereof. The multifunctional burn cream comprises the following traditional Chinese medicine raw materials in parts by weight: 1-20 parts of Chinese ilex leaves, 5-25 parts of coptis chinensis, 5-25 parts of golden cypress, 5-25 parts of scutellaria baicalensis, 5-25 parts of fructus forsythiae, 5-25 parts of radices trichosanthis, 5-15 parts of rheum officinale and 5-15 parts of radix angelicae. The multifunctional burn cream provided by the invention is high in anti-infection capability, and is capable of effectively preventing burn infection, relieving pain of burn wounds, promoting early healing of the wounds and preventing scar hyperplasia and pruritus.
Owner:彭万正
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