222 results about "Neotame" patented technology

Providing a D-psicose-containing sweetener with the modification of the taste of D-psicose, comprising D-psicose, a sugar alcohol and / or a high intensity sweetener, preferably containing D-psicose as the main component, particularly a low-calorie sweetener and / or a sweetener giving refreshing feel in the oral cavity, as well as foods and drinks obtained by using the D-psicose-containing sweetener with the modification of the taste of D-psicose, and other products given with sweetness. The sugar alcohol is one or more sugar alcohols selected from the group consisting of sorbitol, mannitol, lactitol, maltitol, xylitol and erythritol, while the high intensity sweetener is one or more high intensity sweeteners as selected from aspartame, acesulfame K, sodium cyclamate, sodium saccharin, Sucralose (under trade name), stevia sweetener, dulcin, taumatin, neotame and monellin.

The present invention includes a method for producing a chewing gum with a modified release sweetener selected from the group of N-substituted derivatives of aspartame, particularly neotame, as well as the chewing gum so produced. The modified release neotame or other N-substituted derivative of aspartame sweetener is obtained by physically modifying the sweetener properties by coating and drying. Neotame or another N-substituted derivative of aspartame sweetener is coated by encapsulation, partially coated by agglomeration, entrapped by absorption or extrusion, or treated by multiple steps of encapsulation, agglomeration, absorption, or extrusion. The coated sweetener is then co-dried and particle sized to produce a release-modified high-intensity sweetener. When incorporated into the chewing gum, these particles are adapted to enhance the shelf stability of the sweetener and / or produce a modified release when the gum is chewed.

The present invention provides a sweetener composition and methods for improving the taste of a sweetener composition. The sweetener composition includes a mixture of a high-intensity sweetener such as aspartame, encaspsulated aspartame, neotame, encapsulated neotame, cyclamate, sucralose, saccharin or Acesulfame-K, with polyols such as maltitol, sorbitol, mannitol, erythritol, xylitol, lactitol, or palatinit, wherein the high-intensity sweetener is present in the mixture in an amount from about 0.0001% to 15% by weight.

The invention relates to a method for detecting six trace sweetening agents in white spirit by an ultra-high pressure liquid chromatography-time-of-flight mass spectrometry (UPLC-TOF-MS) technology. Particularly, the invention adopts the UPLC-TOF-MS technology and specially aims at the phenomenon of trace addition of a plurality of sweetening agents in the current white spirit industry. The invention can detect six sweetening agents of acesulfame-K, soluble saccharin, sodium cyclamate, sucralose, aspartame and neotame simultaneously, is rapid, simple and convenient, has accurate qualification and quantification and high sensitivity and effectively solves the problem. The method has the detection limit of the acesulfame-K of 0.05mg / L, the detection limits of the soluble saccharin, the sodium cyclamate and the neotame of 0.01 mg / L and the detection limits of the sucralose and the aspartame of 0.1 mg / L, only needs 10 min of one-step sampling analysis and has favorable linear relation and repeatability. Compared with detection data of an authority depart, the data detected by the method is also accurate and reliable.

The invention discloses a composite sweetening agent, belonging to the field of food additives, particularly relates to a sweetening agent and a preparation process thereof. The composite sweetening agent comprises the following ingredients: 10-15 wt% of sodium saccharin, 30-65 wt% of sodium cyclamate, 5-10 wt% of Acesulfame-K, 2-4.75 wt% of aspartame, 0-1 wt% of sucralose, 0-1 wt% of stevioside, 0.1-0.25 wt% of neotame, and 2-5 wt% of synergist. The composite sweetening agent is prepared by scientific proportioning the 7th-generation sweetening agent and adding the synergist as an aid, has the advantages of high sweetness, good mouthfeel, and good stability, can be widely applied in food, forage and health products, and has a huge market prospect.

This invention relates to sweetening compositions used to produce foodstuffs with a sweetness and taste profile comparable to HFCS 55. The sweetener compositions generally include at least one carbohydrate sweetener selected from the group consisting of HFCS 55, HFCS 42 and sucrose along with an effective amount of a high intensity sweetener composition. The high intensity sweetener composition includes acesulfame K and one of either aspartame, sucralose or neotame. Foodstuffs formed using the reduced-calorie sweetener compositions of the invention exhibit a taste profile comparable to HFCS 55 and a calorie reduction of 50% or more.

A preparation process of a fruit can is characterized in that the formula of the fruit can includes following materials by weight: 55%-60% of fruits, 8%-10% of sugar mixture, 0.3% of citric acid, 0.2% of neotame, 0.05% of vitamin C and the balance of water, the sugar mixture includes 60%-70% of xylitol and 30%-40% of fructose, and the xylitol is a novel sweetener and an intermediate of saccharometabolism in a human body and can penetrates through a cell membrane to be absorbed and utilized by tissues without the promotion of insulin under the condition that the saccharometabolism is influenced due to the shortage of insulin in a human body, so that the glycogen is promoted to be synthesized, the nutrition and energy are provided for cells, and the blood glucose value cannot be increased. The fruit can provided by the invention is a low-sugar fruit can which has beautiful pulp color and good mouthfeel and is suitable for the old and the young.

The present invention includes a method for producing a chewing gum with a modified release sweetener selected from the group of N-substituted derivatives of aspartame, particularly neotame, as well as the chewing gum so produced. The modified release neotame or other N-substituted derivative of aspartame sweetener is obtained by physically modifying the sweetener properties by coating and drying. Neotame or another N-substituted derivative of aspartame sweetener is coated by encapsulation, partially coated by agglomeration, entrapped by absorption or extrusion, or treated by multiple steps of encapsulation, agglomeration, absorption, or extrusion. The coated sweetener is then co-dried and particle sized to produce a release-modified high-intensity sweetener. When incorporated into the chewing gum, these particles are adapted to enhance the shelf stability of the sweetener and / or produce a modified release when the gum is chewed.

The invention discloses a feed sweetener, comprising the following components by parts: 70-95 parts of saccharin sodium, 2-5 parts of synergist, 0.2-1.0 part of flavour enhancer and 2-25 parts of glucose, wherein, the synergist is ASP sweet, AK sugar, thaumatin, stevioside and / or maltol; the flavour enhancer is neotame. The feed sweetener is produced by the compound fusion-spray drying method. The feed sweetener has high liquidity, good mouthfeel of sucrose, lasting and stable sweet taste effect and sweet scent flavour. Being added into the feed, the feed sweetener can improve the feed palatability and is suitable for various growth stages of animals.

The invention discloses a method for synchronously detecting six sweetening agents (namely acesulfame, saccharin sodium, sodium cyclamate, aspartame, trichlorosucrose and neotame) in a distilled spirit by using an ultra-high performance liquid chromatography-triple quadrupole tandem mass spectrometer. The method comprises the following steps: performing nitrogen blowing on a wine sample to remove alcohol, separating the wine sample by using an ultra-high performance liquid chromatograph, and then performing multi-reaction ion monitoring mode detection by using a triple quadrupole tandem mass spectrometer. The six sweetening agents have good linear relationships in a range of 50-1000ng / mL, correlation coefficients r2 of the six sweetening agents are more than 0.993, the average recovery rate of the sample is 90-120%, and the limit of detection is 2.69-5.16ng / mL. The method disclosed by the invention is accurate, reliable, simple and fast, and can be used for synchronously detecting the six sweetening agents in the distilled spirit.

The invention relates to a synthesis method of neotame. The method comprises the following steps: (1) adding aspartame and 3,3-dimethyl-butyl aldehyde to an organic solvent in a vacuum state, reacting at the reaction temperature of 20-50 DEG C for 5-24 hours, carrying out concentration and separation at 0-50 DEG C after reaction is ended, concentrating to obtain white paste, adding deionized water to devitrify, thus obtaining a neotame intermediate imine in a centrifuging manner; (2) adding imine and an organic solvent to a hydrogenation reactor, introducing hydrogen until the pressure is 0.1-0.5MPa, adding a catalyst, reacting at the temperature of 35-40 DEG C for 5-30 hours, filtering and removing the catalyst, concentrating the filtrate and removing an organic solvent, and recrystallizing and purifying by water, methanol or ethanol, so as to obtain the neotame. According to the synthesis method, the defects in the prior art are overcome, high-purity imine is generated, the activity of the catalyst is reduced, the selectivity of the catalyst on the imine is increased, the service life of the catalyst is prolonged, the reaction impurity is reduced, and the product purity is improved.

The invention belongs to chemical sciences, and in particular discloses a method for preparing neotame. The method comprises the following steps of: reducing reactants of aspartame and 3,3-dimethyl butyraldehyde to prepare neotame by taking sodium triacetoxyborohydride as a reducing agent; and reducing a reaction solution of the aspartame and the 3,3-dimethyl butyraldehyde, extracting and crystallizing to obtain the neotame. The method for preparing the neotame is easy and convenient to operate, environmental pollution is reduced, and an obtained product has high purity and high yield.

The present invention provides a synthetic method of Neotame, and relates to a sweetener, in particular to a method used for synthesizing the sweetener, Neotame, through the reaction of aspartame, 3, 3-dimethyl butyraldehyde and formic acid. And the present invention provides a synthetic method of Neotame, which has the advantages of simple process and cheap raw materials. The aspartame and the formic acid are added into methanol to prepare mixture A; the weight ratio of the methanol and the aspartame is equal to from 3 to 9 :1; the molar ratio of the formic acid and the aspartame is equal to from 1.2 to 3.0 :1; the 3, 3-dimethyl butyraldehyde is added in the mixture A; the molar ratio of the 3, 3-dimethyl butyraldehyde and the aspartame is equal to from 1.1 to 2.0 :1; after the reaction, the product is concentrated under the condition of reduced pressure to form pulp; and ethanol solution is used for recrystallization to prepare the Neotame.

A salt substitute composition is provided. The salt substitute composition has an amount of potassium chloride and an amount of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester or neotame. The N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester is present in an amount of about 0.001 wt % to about 0.02 wt % of the total weight of the composition. The amount of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester is optimized for reducing the undesired aftertaste of the potassium chloride.

The invention discloses a method for synthesizing neotame, which comprises the following steps of: introducing hydrogen gas with the pressure of 1 to 300KPa into 3,3-dimethyl butyraldehyde and aspartame in an organic solvent under the catalysis of an iridium-based catalyst and carrying out a hydrogenation reaction at the temperature of 10 to 40 DEG C for 5 to 30 hours; filtering to remove the iridium-based catalyst and concentrating filtrate to remove the organic solvent; and recrystallizing and purifying to obtain the neotame. The selectivity of the iridium-based catalyst adopted by the invention to imine is obviously better than the selectivity of the iridium-based catalyst to aldehyde during the catalytic hydrogenation reaction. The defect of low selectivity of palladium or platinum to the imine in the prior art is overcome, and acid also does not need to be added into a reaction system for acidification, so that the reaction progress is quickened by enhancing the pressure, the reaction time is shortened, and the generation of impurities is lowered. The utilization rate of raw materials is enhanced, the purity of the product of the neotame is enhanced, the purity of the product can be greater than 99 percent by simple crystallization, and the production cost is lowered.

The invention discloses a liquid composite high intensity sweeter comprising sweet substances and a solvent. Based on the weight of the sweeter, the sweet substances are one or a plurality of the following components: 0.1-3wt% of aspartame, 0.1-30wt% of sucralose, 0.1-30wt% of acesulfame potassium and 0.01-10wt% of neotame. In addition, the invention further discloses a method for preparing the liquid composite high intensity sweeter. The liquid composite high intensity sweeter is obtained by dissolving the sweet substances into the solvent, not only has the similar sweet taste to sucrose and several times to thousandfold higher sweetness than sucrose, is mixed uniformly, and has no particles remained; the product quality and the convenience in use are beneficially improved, and the actual requirements of production and consumption are well satisfied; and meanwhile, the method for preparing the sweeter provides an effective guarantee for the quality and the edible safety of sweeter products.

The invention discloses a gel soft sweet 3D print material capable of selectively loading complex polysaccharide, and a preparation method of the gel soft sweet 3D print material. The 3D print material is obtained through decocting raw materials, and the raw materials comprise the following components in parts by weight of 1.2 parts of gellan gum, 12 parts of agar, 12 parts of gelatin, 4 parts ofstarch, 50 parts of liquid maltitol, 44 parts of erythritol, 0.5 part of polyglycerol polyricinoleate, 0-0.05 part of Neotame, 0-0.5 part of mint powder and 0-20 parts of complex polysaccharide, and the solid content at decoction finish is preferably 70%-76%. Key components of the gel soft sweet 3D print material capable of selectively loading complex polysaccharide, the integrated technology process design of the corresponding preparation method and parameter conditions adopted by the processing technology are improved, so that the problem the kinds of print materials used by 3D print of foods is limited can be effectively solved. The gel soft sweet 3D print material capable of selectively loading complex polysaccharide expands the kinds of the print materials of 3D print of foods, and provides possibility for the application of a 3D printing technique in the field of foods.

The invention discloses a melissa pollen drink and a preparing method thereof, comprising pretreatment of the melissa pollens, performing cell wall breaking treatment combining temperature difference wall breaking and mechanical wall breaking, cold-storage standing, centrifugating, filtering, fixing volume, filling and other processes to prepare clear melissa drink. In addition, the invention uses neotame as sweetener to substitute the original high-concentration cane sugar. The sugar-free and clear melissa pollen drink of the invention prepared by the processes solves the problems of flocculent precipitates and easy acetification caused by high concentration of sugar, and losing nutrient components caused by low wall breaking rate of the pollen, improves utilization rate of melissa pollens, l lowers the cost, provides a novel drink for markets and has a great economic value.

The invention belongs to the field of food additives, particularly relates to a sweetening agent, and more particularly relates to a method for synthesizing neotame through catalytic hydrogenation of N-alpha-L-aspartic phthalein-L-phenylalanine 1-methyl ester and 3,3-dimethyl butyraldehyde. A synthetic method of neotame is characterized in that Pd / C is taken as a catalyst to perform the catalytic hydrogenation of an ethanol solution of N-alpha-L-aspartic phthalein-L-phenylalanine 1-methyl ester and 3,3-dimethyl butyraldehyde so as to synthesize neotame. The synthetic method disclosed by the invention has the beneficial effects that neotame prepared by the method disclosed by the invention has a yield as high as 83% and liquid-phase purity as high as 98.7%; moreover, in comparison with the synthetic method in the background art, the method disclosed by the invention is beneficial for industrial production, low in cost and simple in experimental procedures.

The invention provides a feed additive replacing antibiotics for preventing weaned piggies from suffering from diarrhoea. The additive is prepared from the following raw materials of bacillus licheniformis, enterococcus faecalis, clostridium butyricum, a sweetening agent (5% neotame), cupric sulfate pentahydrate, manganese sulfate monohydrate, ferrous sulfate monohydrate, zinc sulfate monohydrate, tributyrin, an antioxidant, montmorillonite and fermented apple pomace. The feed additive disclosed by the invention can improve the microenvironment of intestinal tracts of piggies, repair damaged intestinal mucosa, strengthen digestive absorption functions, strengthen the immunity of the piggies, promote the growth of the piggies, adsorb mycotoxin in feeds at the same time, effectively prevent the weaned piggies from suffering from diarrhoea and increase economic returns.

The invention relates to a food additive and particularly relates to a compound sweetening agent containing neotame and capable of being used in an areca-nut food. The invention provides the compound sweetening agent containing the neotame and capable of being used in the areca-nut food, which is composed of following components in mass percentage: 0.6%-1.0% of the neotame, 2.5%-4.0% of thaumatin, 25%-30% of erythritol, 25%-40% of maltitol, 30%-40% of sorbitol, 1%-3% of a flavor correcting matter and 0.2%-2% of an anti-caking agent. The compound sweetening agent is compounded scientifically and reasonably so as to have the advantages of soft sweetness, strong solubility, good stability, high safety, low sweetness cost and the like.

The present invention discloses a novel compound sweeting agent with vinculum sweet. According to 100 times of the sweet degree of the cane sugar, the combination and the compounding ratio are: 60 percent to 85 percent of the dextrin, 0.5 percent to 1.5 percent of the vinculum sweet, 5 percent to 15 percent of the stevia sugar, 5 percent to 15 percent of the sweet honey element, and 1 percent to 10 percent of the Aspartame, and the percent content is the weight percent content. The compound sweeting agent of the invention is manufactured well by smashing the materials according to compounding ratio for average mixing. The compound sweeting agent is the compound sweeting agent compounding with the novel high-time sweeting agent through scientific and proper repeatedly compounding, which has good tasting and low cost as well as health protection without sugar and wide market prospect.

The invention discloses a preparation method of a feed additive capable of improving the production performance of growing pigs and lowering the diarrhea rate, which can replace antibiotics. The feed additive is prepared through taking ferrous glycine chelate, selenium yeast, saccharomyces cerevisiae cytoderm, vitamin additives, bacillus subtilis, saccharomyces cerevisiae, protease, cellulase, phytase, Neotame and an (I+G) flavoring agent as main components and taking fermented apple dreg and montmorillonite as carriers. The vitamin additives comprise vitamin A, vitamin D3 and vitamin E. The raw materials are compounded and all the raw materials have a synergistic effect. The feed additive has the functions of improving the organism immunity, adjusting the balance of intestinal flora and adsorbing mycotoxin, so that the diarrhea rate is lowered and the production performance of the growing pigs is improved.

The invention discloses a sweet and cool tipping paper gravure alcohol-soluble surface coating and tipping paper prepared therefrom. The sweet and cool tipping paper gravure alcohol-soluble surface coating comprises the following raw materials by weight: 0.1 to 0.3% of a sweetening agent prepared from neotame, mannitol, a rosvenor momordica fruit extract and fine moringa seed powder with a particle size of 1000 meshes, 15 to 20% of WS-23(N,2,3-trimethyl-2-isopropylbutanamide) cooling agent, 30 to 36% of polyvinyl butyral, 4 to 5% of castor oil, 1.6 to 2% of wax micropowder, 2.5 to 3% of whitecarbon black and 33.7 to 46.8% of edible ethanol. According to the invention, the tipping paper printed by using the sweet and cool tipping paper gravure alcohol-soluble surface coating provided by the invention is smoother, brighter, stain-resistant, water-resistant and wear-resistant in surface, has special sweet and cool tastes, and tastes cool and sweet; wear resistance, folding resistance andfunctionality of a printed product are reinforced to a great extent; and the reputation of he product is improved.

This invention discloses a synthesis method for Neotame. The said method includes the following steps: (1) carrying out a reaction of tert-butanol with hydrochloric acid to obtain tert-butyl chloride; (2) adding catalyst in tert-butyl chloride, and charging ethylene gas and reacting to obtain 3, 3-dimethyl-1-chlorobutane; (3) oxidating 3, 3-dimethyl-1-chlorobutane to obtain 3, 3-dimethyl butyraldehyde, and purifying; and (4) carrying out a reaction of 3, 3-dimethyl butyraldehyde with aspartame to form imine, and catalytic-hydrogenating to obtain Neotame. The invention has the advantages of simple process, easy operation, low cost, and high purity of the product.

The invention discloses a feed additive for weaned pigs. The feed additive is prepared from the following components in parts by weight: 20-30 parts of corn gluten meal, 10-15 parts of bentonite, 4-5 parts of palm oil, 4-5 parts of choline, 2-3 parts of sodium butyrate, 2-3 parts of taurine, 2-3 parts of N-carbamyl glutamic acid, 2-3 parts of sucrose fatty acid ester, 2-3 parts of algal polysaccharide sulfate, 1-2 parts of lysine, 1-2 parts of a trace element premix, 1-2 parts of phosphorylase, 0.8-1 part of lactobacillus, 0.5-0.6 part of saccharomycetes, 0.1-0.2 part of tea polyphenol, 0.1-0.2 part of chitosan, 0.04-0.05 part of squalane and 0.01-0.02 part of Neotame. Aiming at the gastrointestinal digestive problem of the weaned pigs, the feed additive is compounded scientifically, so that the immunity of the weaned pigs is favorably enhanced and diarrhea is effectively reduced, and meanwhile, the feed additive has a relatively good anti-deterioration property.

The invention provides a wheat germ healthy food. The wheat germ healthy food is prepared from the following raw materials in parts by weight: 30-70 parts of wheat germ powder, 10-20 parts of maltodextrin, 10-20 parts of milk powder, 1-5 parts of hydroxypropyl-beta-cyclodextrine, 1-10 parts of radix puerariae powder, 0.5-3 parts of inulin, 1-3 parts of red date powder, 1-2 parts of whey protein, 0.5-5 parts of soya bean lecithin, 0.2-1.3 parts of tricalcium phosphate, 0.2-1.3 parts of silicon dioxide, 0.005-0.1 parts of se-enriched yeast, 0.01-0.1 parts of zinc lactate, 1-5 parts of fructo-oligosaccharide, 1-20 parts of white granulated sugar, 1-5 parts of xylitol, 0.01-0.2 parts of neotame, 0.01-0.2 parts of aspartame, 0.02-0.1 parts of vitamin C, 0.02-0.2 parts of vitamin E, 0.05-0.2 parts of beta-carotene, 0.1-0.3 parts of alpha-linolenic acid, 0.01-0.5 parts of sodium alginate, 0.1-2 parts of xanthan gum, and 0.1-2.5 parts of CMC-Na.

The invention provides a solid alcohol solid dispersion combination of EGCG (epigallocatechin gallate) with thermal stability and sugar alcohols. The sugar alcohols include one or more ingredients comprising fructose, newtol, fructo-oligose, xylooligosaccharide, polydextrose, mannitol, cane sugar, glucose, resistant dextrin, sorbitol, maltose, isomalt, mannose oligomer, carbo wax, dextrin, cyclodextrin, hydroxyl-lpropyl-beta-cyclodextrin, microcrystalline cellulose, carboxymethylcellulose, pregelatinized starch, starch, starch sugar, lactose, sodium carboxymethyl starch, proteoglycan, sucralose, aspartame, acesulfame, stachyose, neotame and stevioside, and the sugar alcohols and the EGCG are in (12-80):1 in proportion by weigth. The invention further provides a preparation method of the solid dispersion combination and application in preparation of the solid dispersion combination. By the aid of the solid dispersion combination, the EGCG is effectively improved in stability.

The invention discloses a synthesis process of neotame. The synthesis process comprises the following steps: adding aspartame into a reaction container, performing water-bath heating to 33-35 DEG C, further adding 3,3-dimethyl butyraldehyde, heating to 30-60 DEG C, performing heat preservation reaction for 55-70 minutes, then adding a catalyst at the temperature, and introducing hydrogen for reacting for 14-16 hours; after the end of the reaction, filtering the catalyst to get filtrate, further washing the catalyst with an appropriate amount of methanol, merging the filtrate and washing liquid, performing vacuum distillation at the temperature of 40-50 DEG C, distilling obtained solids, further adding water, cooling, crystallizing, filtering at the temperature of less than 5 DEG C, drying and crushing to get a crude product; and adding 15-40% ethanol into the crude product, drying and crushing to get a final neotame finished product. According to the synthesis process of the neotame, the yields of the crude product and the finished product are greatly improved, the yield of the crude product can be improved from the current 70-72% to above 90%, the yield of the finished product can be improved from the current about 65% to above 80%, and the quality of the finished product has no difference in comparison with that of the finished product synthesized by the prior art.