69 results about "Trichlorosucrose" patented technology

The invention discloses a maca composite beverage. The beverage is prepared from raw materials of, calculated by 800 to 1200kg of the beverage: 10 to 20kg of maca, 10 to 30kg of okra, 1 to 5kg of male silk moth, 0.1 to 0.5kg of arginine, 0.1 to 0.5kg of potassium sorbate, 1 to 3.5kg of citric acid, 0.05 to 0.15kg of trichlorosucrose, and an appropriate amount of water. The maca composite beverage contains no sugar and low heat. The beverage provides healthcare functions of fatigue resisting, pressure releasing, health enhancing, body strengthening, and male function enhancing. The invention also discloses the preparation method of the maca composite beverage. Maca, okra, male silk moth, arginine, citric acid, trichlorosucrose and potassium sorbate are adopted as main materials; the materials are processed through enzymolysis, extracting, mixing and filtering, such that the composite beverage is prepared. The operation is simple, and the method is suitable for industrialized productions.

The invention relates to a preparation method of an intermediate of the food sweetening agent trichlorosucrose, belonging to the technical field of fine chemicals. The theory of the invention is as follows: chloroethane is used as reaction solvent, thus replacing dimethyl formamide (DMF) which is generally used as solvent; and DMF is used as catalyst, thereby greatly reducing the dosage of DMF and saving the cost; and the generated hydrogen chloride and sulfur dioxide can fast leave the reaction system, thereby reducing side reactions. The preparation method has the following beneficial effects; the method has low cost and less reaction steps, the yield is obviously improved by about 20% compared with the method using DMF as solvent, and the preparation method has obvious advantages.

The invention discloses a method for synchronously detecting six sweetening agents (namely acesulfame, saccharin sodium, sodium cyclamate, aspartame, trichlorosucrose and neotame) in a distilled spirit by using an ultra-high performance liquid chromatography-triple quadrupole tandem mass spectrometer. The method comprises the following steps: performing nitrogen blowing on a wine sample to remove alcohol, separating the wine sample by using an ultra-high performance liquid chromatograph, and then performing multi-reaction ion monitoring mode detection by using a triple quadrupole tandem mass spectrometer. The six sweetening agents have good linear relationships in a range of 50-1000ng / mL, correlation coefficients r2 of the six sweetening agents are more than 0.993, the average recovery rate of the sample is 90-120%, and the limit of detection is 2.69-5.16ng / mL. The method disclosed by the invention is accurate, reliable, simple and fast, and can be used for synchronously detecting the six sweetening agents in the distilled spirit.

The invention provides a health care food used for increasing bone mineral density, preventing osteoarthrosis and enhancing immunity. The health care food is prepared from the following materials in parts by mass: 1500-2500 parts of marine fish bone collagen oligopeptide, 1500-2500 parts of fish bone powder, 200-400 parts of eucommia bark extract and 0.005-0.01 part of vitamin D and a proper amount of pharmaceutic adjuvants such as xylitol, dry skim milk, vegetable fat powder, essences, trichlorosucrose and the like. The health care food is prepared into a granular preparation by the following process steps of: premixing, granulating, total mixing and the like. The invention has the beneficial effects that the raw materials, i.e., marine fish bone collagen oligopeptide and fish bone whichcontain a large quantity of peptide, bone collagen and calcium, work together with eucommia bark extract and vitamin D in the health care food so that a human body can absorb effective ingredients better to increase bone mineral density, slow down bone marrow aging, enhance toughness of bones, and prevent and treat osteoporosis; in addition, peptide also has the functions of adjusting immunity and resisting bacteria and oxidation, thereby improving the immunity of the human body.

The invention relates to a method for comprehensively utilizing trichlorosucrose production waste gas, which comprises steps as follows: chlorine hydride and sulfur dioxide generated in a trichlorosucrose chlorination step are sent into a low-temperature condenser (E-1) to be cooled at the low temperature of -100 to -10 DEG C to implement initial separation of chlorine hydride and sulfur dioxide, and the sulfur dioxide enters a low-temperature storage tank (E-2); hydrogen chloride gas containing trace amounts of sulfur dioxide is dried by a concentrated sulfuric acid kettle (E-3) and enters a reaction kettle (E-4) to react with alcohol and acetonitrile; and the salification reaction between the chlorine hydride and the alcohol / acetonitrile is utilized to absorb the chlorine hydride tail gas, and the obtained salt reacts with ammonia gas to obtain the triorthoacetate required by the trichlorosucrose esterification step. The method implements comprehensive utilization of waste inside the production system, and lowers the product cost on the premise of reducing waste discharge. The tail gas chlorine hydride is utilized to prepare the raw material required by the production of trichlorosucrose, thereby changing wastes into valuable substances.

The invention discloses a Perilla frutescens nutritional healthcare chewable tablet, which comprises the following components: Perilla frutescens leaf powder, Perilla frutescens extract dry powder, microcrystalline cellulose (MCC), oligoisomaltose, milk sugar, Perilla frutescens essence, vitamin C, magnesium stearate, gastric-soluble coating materials, stevioside, trichlorosucrose, erythritol, mannitol, xylitol, citric acid, plum jam and collagen peptides. The chewable tablet tastes good, is convenient to eat and easy to carry, and has a long shelf life, a certain nutritional value and an effect of promoting health.

The invention discloses a pecan-milk compound protein beverage and a processing method thereof. The pecan-milk compound protein beverage is characterized by comprising the following raw materials: pecan kernels, whole milk powder, a compound stabilizer, white granulated sugar, concentrated jujube juice, edible salt, starch, sodium caseinate, sodium tripolyphosphate, sodium citrate, trichlorosucrose, sodium hydrogen carbonate, edible essence and water. The processing method comprises the following steps: screening, rinsing, finely grinding, dissolving milk powder, dissolving white granulated sugar, dissolving ingredients, blending with the jujube juice, homogenizing, sterilizing, filling and sterilizing. The pecan-milk compound protein beverage has a peculiar fragrance of pecans and rich nutrition of the whole milk powder, has a unique milk red color of a pecan beverage, and has good color, fragrance and taste; the pecans and the milk powder are mixed in one beverage product, so that the pecan-milk compound protein beverage is more balanced in nutrition and has a gentle mouth feel at the same time.

The invention discloses a preparation method for freshening monosodium glutamate. The invention aims to provide a production method for freshening monosodium glutamate. The preparation method is characterized by comprising the following raw materials in proportion by weight: 165-175 parts of sodium glutamate, 13-14 parts of disodium 5'-ribonucleotide, 19-20 parts of disodium succinate and 0.2-0.3 part of trichlorosucrose. The preparation method comprises the following steps of: A, uniformly mixing the sodium glutamate, disodium 5'-ribonucleotide and disodium succinate according to the proportion to obtain a mixture; and B, putting the mixture obtained from the step A to a pulverizer for pulverizing to obtain a product. The freshening monosodium glutamate prepared by preparation method is mainly used as a freshening additive for soy sauce.

The invention discloses fosfomycin calcium composition freeze-dried orally disintegrating tablets and a preparation method of the orally disintegrating tablets, relates to the field of a medicine and a medicine preparation method technology and mainly solves the problems in the prior art that the oral preparation made from fosfomycin calcium is poor in administration compliance for children and calcium salt orally taking absorption rate. The fosfomycin calcium composition freeze-drying orally disintegrating tablets are prepared from the following components by weight: 10-24% of fosfomycin calcium, 24-50% of mannitol, 2-4% of gelatin, 32-74% of hydroxypropyl-beta-cyclodextrin with medium substitution degree, 0.1-0.2% of trichlorosucrose and 50% of purified water. The fosfomycin calcium composition freeze-drying orally disintegrating tablets obtained by the above components are easy in preparation process, and simple in components, and mainly aim at the administration requirements of the children; moreover, the fosfomycin calcium composition freeze-drying orally disintegrating tablets have the advantages of being fast to disintegrate, convenient to take and good in taste; and the tablets take effect quickly and are fully absorbed, and the first pass effect of the liver is avoided.

The present invention provides a method for preparing key intermediate-sucrose-6-organic acid ester for preparing trichlorosucrose. Said method includes the following steps: using N,N-dimethylamidodimethylacetal compound and sucrose as raw material, making them produce reaction to form ring, then making hydrolysis so as to obtain the invented sucrose-6-organic acid ester.

The invention relates to a moisturizing and moistureproof composition and an application thereof and a moisturizing and moistureproof method. Based on the total weight of the moisturizing and moistureproof composition, the moisturizing and moistureproof composition comprises 0.01-50.0% of tremella heteropolysaccharide, 0.02-5.0% of momordica grosvenori extract, 0.01-1.0% of trichlorosucrose, 3.0-15% of glycerol, 3-8% of hyaluronic acid and 20.0-85.0% of propylene glycol. The moisturizing and moistureproof composition can form a biomimetic membrane on the surface of material, especially the surfaces of dry leaves of plants and the surface of baking food, and sensitivity of moisture in the material to the environment is reduced, thus moisturizing and moistureproof effects are achieved. Compared with the traditional polyalcohol and amino acid moisturizers, or sodium hyaluronate and tremella heteropolysaccharide moisturizers, the moisturizing and moistureproof composition provided by the invention has more excellent membrane-forming performance, more excellent membrane flexibility and higher moisturizing ability and moistureproof performance.

The invention discloses brain-strengthening health nutrient solution. The brain-strengthening health nutrient solution is composed of the following substances in parts by mass: 500-2000 parts of solution, 20-60 parts of glucose, 1-5 parts of caffeine, 1-3 parts of vitamin A, 2-6 parts of vitamin B, 1-7 parts of vitamin D, 4-10 parts of organic selenium, 10-18 parts of zinc gluconate, 2-16 parts of maltodextrin, 1-9 parts of N-acetyl glucosamine, 5-25 parts of II type collagen, 3-8 parts of xylitol, 1-6 parts of menthol, 2-9 parts of trichlorosucrose, 1-4 parts of lycium barbarum polysaccharide, 2-13 parts of poria cocos polysaccharide, 6-19 parts of tea polyphenol and 1-4 parts of fatty acid sucrose ester. By adopting the manner, the brain-strengthening health nutrient solution has the effects of refreshing and restoring consciousness and is good in absorption effect and wide in applicability.

The invention discloses a skin care beautifying black Chinese wolfberry candy and a preparation method thereof, the skin care beautifying black Chinese wolfberry candy is characterized in that effective ingredients comprise the following raw materials: black Chinese wolfberry powder, tartary buckwheat powder, jujube powder, Coix Seed powder, honey powder and soybean germ powder, and auxiliary ingredients comprise maltodextrin, microcrystalline cellulose, citric acid, Trichlorosucrose and magnesium stearate. The black Chinese wolfberry as a core, and is blended with the tartary buckwheat powder, the jujube powder, the Coix Seed powder, the honey powder and the soybean germ powder, and the black Chinese wolfberry effect is enhanced. The skin care beautifying black Chinese wolfberry candy can regulate body, tonify deficiency, benefit qi, nourishing blood, soothe the nerves and relieve the deficiency of qi and blood, and has a better effect to improve skin quality, remove spots and acnes, and brighten skin color. Through use of superfine grinding technology, the skin care beautifying black Chinese wolfberry candy is more conducive to the absorption and utilization of the human body, and the trouble of boiling and processing is omitted, and the skin care beautifying black Chinese wolfberry candy is convenient to carry and directly take.

The invention discloses a method for efficiently synthesizing trichlorosucrose, belonging to the field of organic synthesis. The method comprises the following steps: carrying out alcoholysis on trichlorosucrose-6-ethyl ester in a strong-acid macroporous ion exchange resin / methanol system at 40-70 DEG C, and carrying out after-treatment to obtain the finished trichlorosucrose product. Sucrose-6-ethyl ester, which serves as the raw material, is subjected to alcoholysis reaction to prepare the product in one step. Thus, the method has the advantages of simple technique, mild reaction conditions, high selectivity, high product purity, high yield and easy after-treatment, conforms to requirements for environmental protection, and is very suitable for industrial production.

The invention discloses a high-efficiency crystallization method of trichlorosucrose, belonging to the field of compound treatment. The method comprises the following steps: holding trichlorosucrose solution with a certain of sugar degree within a certain temperature range to promote nucleation, and cooling according to a periodic procedure to promote crystal nucleus to grow quickly, thereby achieving the goal of high-efficiency crystallization. The invention solves the problems of incomplete crystallization, irregular crystal shape and low yield in the trichlorosucrose crystallization process, has the advantages of simple steps and high efficiency, and is very suitable for industrial production.

The invention discloses a maca composite beverage. The beverage is prepared from raw materials of, calculated by 800 to 1200kg of the beverage: 10 to 20kg of maca, 10 to 30kg of okra, 1 to 5kg of male silk moth, 0.1 to 0.5kg of arginine, 0.1 to 0.5kg of potassium sorbate, 1 to 3.5kg of citric acid, 0.05 to 0.15kg of trichlorosucrose, and an appropriate amount of water. The maca composite beveragecontains no sugar and low heat. The beverage provides healthcare functions of fatigue resisting, pressure releasing, health enhancing, body strengthening, and male function enhancing. The invention also discloses the preparation method of the maca composite beverage. Maca, okra, male silk moth, arginine, citric acid, trichlorosucrose and potassium sorbate are adopted as main materials; the materials are processed through enzymolysis, extracting, mixing and filtering, such that the composite beverage is prepared. The operation is simple, and the method is suitable for industrialized productions.

The invention discloses a table vinegar, in particular to an apple vinegar, and belongs to the technical field of food processing. The apple vinegar comprises the following raw components in parts by mass: 15-25 parts of raw vinegar, 0.01-0.02 part of trichlorosucrose, 15-25 parts of fructose-glucose syrup, 0.02-0.05 part of acesulfame, 0.1-0.5 part of malic acid, 0.3-0.6 part of lactic acid, 0.1-0.3 part of citric acid, 10-20 parts of white granulated sugar, 0.01-0.03 part of ethyl maltol, 0.6-0.9 part of apple essence and 1-3 parts of glacial acetic acid. After the adoption of the raw components in parts by mass, due to reasonable collocation of the components and reasonable selection of proportions of the components, the apple vinegar is good in taste, a variety of tastes are increased, the nutritional value is improved, and needs of people on acetic acid with special aroma can be met; the material cost is low, so that the production cost is greatly reduced; more importantly, functions of keeping a body in good health, relieving fatigue, beautifying the skin and the like are further improved; the apple vinegar can be used as a raw stock of vinegar beverages as well as a base stock of beverages and cocktails.

The invention provides roxithromycin composition freeze-dried orally disintegrating tablets and a preparation method of the orally disintegrating tablets, relates to the field of a medicine and a medicine preparation method technology and mainly solves the problems in the prior art that the oral preparation made by roxithromycin is not suitable for children, old people, bedridden patients, patients suffering from serious disability and the patients who are difficult to swallow. The roxithromycin composition freeze-dried orally disintegrating tablets are prepared from the following components by weight: 30-66% of roxithromycin, 33-66% of mannitol, 2-4% of gelatin, 0.1-0.15% of trichlorosucrose and 50-70% of tertiary butanol-water. The roxithromycin composition freeze-dried orally disintegrating tablets prepared by the above components are easy in preparation process, and simple in components, and mainly meet the administration requirements of children, old people, bedridden patients, patients suffering from serious disability and the patients who are difficult to swallow; moreover, the roxithromycin composition freeze-dried orally disintegrating tablets have the advantages of being fast to disintegrate, convenient to take, and good in taste; and the tablets take effect quickly and are fully absorbed, and the first pass effect of the liver is avoided.

Methods for chlorinating sucrose-6-esters to produce 1',4,6'-trichlorosucrose-6-esters include providing a reaction mixture in a temperature-controlled vessel at a temperature less than about 65 DEG C, the reaction mixture comprising sucrose-6-ester, a tertiary amide, and a chloroformiminium chloride salt, which forms an O-alkylformiminium chloride adduct with the hydroxyl groups of the sucrose-6-ester. The methods for chlorinating the sucrose-6-ester further include subjecting the chloroformiminium chloride salt, tertiary amide, and sucrose-6-ester reaction mixture to an elevated temperature between about 75 DEG C and 100 DEG C for a period of time sufficient to produce a chlorinated product mixture of chlorinated sucrose-6-ester products consisting essentially of 1',4,6'-trichlorogalacto-sucrose-6-ester.

The invention designs a traditional Chinese medicine health tea which comprises ethyl maltol, sodium citrate, salt, monosodium glutamate, ganoderma triterpene, calcium phosphate, carrageenan, cordyceps polysaccharide, puerain, sucrose fatty acid ester, trichlorosucrose, green tea, mulberry, longan pulp, wolfberry, lotus seed, sealwort, spina date seed, the root of kudzu vine, semen cassiae and lucid ganoderma. The traditional Chinese medicine health tea is prepared by adopting traditional Chinese medicine components, and has the health functions of tonifying the liver and nourishing the kidneys, tranquilizing mind by nourishing the heart, reducing blood pressure, reducing blood lipid, lowering blood sugar level, tonifying qi and blood, gutting purge and relaxing the bowels and resisting radiation; in the aspect of nutritional components, the tea has low heat energy, low fat and low sugar level, and has natural, healthy, thirst-quenching and health-preserving characteristics; and in the aspects of taste and nutritive values, compared with various commercially available beverages, the tea provided by the invention has more comprehensive nutrition, obvious health effect, refreshing and non-irritant taste, natural flower and plant faint scents and rich health components, and meets the international health development trend.

The invention discloses a crystallization method for improving the stability of trichlorosucrose. The method comprises the steps of adding a concentrate or solid containing the trichlorosucrose into a mixed solvent of alcohol solvent or alcohol and water, adding mother liquor which is obtained by decompression and concentration and accounts for a certain proportion of the weight of the concentrate or solid containing the trichlorosucrose after the crystallization of a former batch of product, then adding a buffering agent, heating until the mixture is dissolved completely, decoloring, filtering, then reducing the temperature gradually, crystallizing, filtering and drying to obtain trichlorosucrose crystals. The method has the advantage that the equipment is simple, the operation is easy, the product can be stored for a long time without generating the smell of acetic acid and the like, and the due to the recycling of the mother liquor, the waste of the product in the mother liquor is reduced, and the product yield is improved greatly.

The present invention provides an amino acid drink, and 100mL of the amino acid drink comprise compound amino acid powder, fructose, taurine, vitamin B6, vitamin B12, maltodextrin, sodium alginate, trichlorosucrose, citric acid, malic acid, sodium citrate, fruit flavor essence and balance of purified water. The amino acid drink can reduce fatigue and improve immunity of people drinking the amino acid drink, may not bring side effects to the human body after long term drinking of the amino acid drink, can improve the liver function, renal function and gastrointestinal function, promotes intellectual development, enhances memory, maintains normal human blood pressure, prevents arteriosclerosis, can release energy, maintains a healthy nervous system, is good in taste and low in calories, may not cause fattening due to heat accumulation after drinking, promotes normal human body material metabolism, and is a healthy drink.

The invention relates to a coffee flavor traditional Chinese medicine partner which can be used for effectively solving the problems that the traditional Chinese medicine decoction is bitter and astringent in mouthfeel and has objectionable odor. The technical scheme adopted by the invention is as follows: the traditional Chinese medicine partner is prepared from the following raw materials by weight percent: 3-5% of black coffee, 14-35% of non-dairy creamer, 5-20% of beta-cyclodextrin, 40-65% of saccharose and 0.03-0.2% of trichlorosucrose; the coffee flavor traditional Chinese medicine partner is prepared by grinding the black coffee and the saccharose, evenly mixing the trichlorosucrose with the black coffee by an equal incremental method, evenly mixing the mixture with the non-dairy creamer, the beta-cyclodextrin and the saccharose, drying at 55-65 DEG C, cooling to the room temperature of 18-25 DEG C, and performing split charging. The coffee flavor traditional Chinese medicine partner is a nutritious food capable of solving the bitter and astringent mouthfeel of the traditional Chinese medicine decoction, and enables the taste to be sweet and palatable; the nutritious food not only is easy to digest and absorb by a human body, but also is capable of improving the bad mouthfeel of traditional Chinese medicine, thus being easy to take by a patient; the coffee flavor traditional Chinese medicine partner can be separately taken, and has the functions of increasing the nutritional ingredients of the human body and being beneficial to the health.

The invention discloses low-calorie sugar of sucralose and a preparation method. Low-calorie sugar of sucralose is made of sucralose, silica, maltodextrin, lactose or glucose or fructose syrup. The raw material is mixed with clean water or ethanol by a certain proportion to form pulp and then the finished product is generated after spraying, drying and crushing.

Disclosed is a method of chlorinating a carbohydrate or derivative thereof, for example, a sucrose-6-ester at the 4,1′, and 6′ positions, with irreversible removal of HCl formed during the reaction to form the chlorinated carbohydrate or derivative thereof, for example, a 4,1′,6′-trichloro-4,1′,6′-trideoxy-6-O-ester of galactosucrose (TGS-6E). The irreversible removal of HCl can be carried out by an irreversible physical process and / or an irreversible chemical process. Sucralose, an artificial sweetener, can be prepared by deesterification of the TGS-6E. The chlorination reaction takes place at low temperatures and the desired chlorinated product is obtained in high yields and in high purities.

An improved production method of sucralose is characterized by comprising the steps: (1) methoxy on benzene ring is used for replacing the three ortho-hydroxide radical of 6, 1' and 6' in trityl chloride etherified sucrose molecules and acylation reaction is carried out to prepare 6, 1', 6'-trimethoxy benzyl-penta acetic sucrose through etherealization and fine purification; (2) etherealization and acyl removal reactions are carried out to the 6, 1', 6'-trimethoxy benzyl-penta acetic sucrose in water-bearing weak acid at the same time, product 6-PAS generated from the reaction is refined and enters into the next chlorination reaction step; (3) 4, 1', 6'- trichloro-4, 1', 6'-trideoxidation galacto-sucrose (namely the sucralose) is prepared through the chlorination and acyl reaction of the 6-PAS. The invention combines the advantages of a full protective line and a single protective line, spurns the defects of the existing production methods and changes the original 'five steps' of the full protective line into 'four steps', thereby promoting the recovery rate of the full protective line greatly with less reaction steps and consumption, thus resulting in a more economic and environment protective production technology compared with the traditional production technologies of the full protective line or the single protective line.

The invention provides cefuroxime axetil composition freeze-dried orally disintegrating tablets and a preparation method of the orally disintegrating tablets, relates to the field of a medicine and a medicine preparation method technology and mainly solves the problems in the prior art that the cefuroxime axetil preparation is poor in curative effect and not suitable for children and the patients who are difficult to swallow. The cefuroxime axetil composition freeze-dried orally disintegrating tablets are prepared from the following components by weight: 25-50% of cefuroxime axetil, 25-75% of mannitol, 2-4% of gelatin, 0.1-0.15% of trichlorosucrose and 42-67% of tertiary butanol-water. The cefuroxime axetil composition freeze-dried orally disintegrating tablets prepared by the above components are easy in preparation process, and simple in components, and mainly meet the administration requirements of children and the patients who are difficult to swallow; moreover, the cefuroxime axetil composition freeze-dried orally disintegrating tablets have the advantages of being fast to disintegrate, convenient to take, and good in taste; and the tablets take effect quickly and are fully absorbed, and the first pass effect of the liver is avoided.

The invention discloses a deacylation method of sucralose-6-acetate. The method comprises the following steps: under the action of Lewis acid, carrying out deacylation reaction on a sucralose-6-acetate-containing reactant in an alcohol solvent; after the reaction is completed, performing concentrating, and adding water; adding alkali liquor to form colloid or precipitate; and removing the colloidor precipitate, and performing purifying to obtain a sucralose product. The deacylation method can reduce the decomposition of TGS (trichlorosucrose), has higher product yield, can better remove impurities in the after-treatment process, and is more convenient to operate.

The invention discloses calcium-supplementing health nutrient solution. The calcium-supplementing health nutrient solution is composed of the following substances in parts by mass: 100-700 parts of aqueous solution, 5-15 parts of shark cartilage extract, 1-6 parts of calcium malate citrate, 2-8 parts of calcium chloride, 3-9 parts of calcium citrate, 2-5 parts of calcium lactate, 4-12 parts of calcium gluconate, 4-8 parts of calcium glycinate, 1-3 parts of calcium ascorbate, 5-15 parts of vitamin PP, 1-4 parts of inositol, 6-11 parts of glucosamine hydrochloride, 7-12 parts of trichlorosucrose and 1-5 parts of methyl salicylate. By adopting the manner, the calcium-supplementing health nutrient solution has the advantages that a calcium absorption effect can be improved, stability is good, applicability is wide, and taste is good.