The invention relates to application of
cynomorium songaricum extractive in the preparation of an
antidepressant drug, can effectively solve the problem about the preparation of the
antidepressant drug, and realizes the application of the
cynomorium songaricum extractive in the preparation of the
antidepressant drug. The
cynomorium songaricum extractive is prepared through the following steps: taking cynomorium songaricum medicinal materials, smashing the cynomorium songaricum medicinal materials into coarse
powder, soaking with ethyl
alcohol, performing the
reflux extraction, recycling the ethyl
alcohol from the filtrate through
pressure reduction until the
alcohol taste is eliminated, so as to obtain a cynomorium songaricum extracting solution; soaking
macroporous resin with ethyl alcohol, and performing wet-process packing; dispersing the cynomorium songaricum extracting solution into dispersion liquid by using
distilled water, adjusting the pH value to 4.5, adding
macroporous resin columns, eluting by using
distilled water, and removing the eluent; continuously eluting by using ethyl alcohol, and removing the eluent; then eluting by using ethyl alcohol again, collecting the ethyl alcohol eluent, recycling the ethyl alcohol through
pressure reduction,
drying, and smashing, so as to obtain the finished product. According to the invention, the prepared cynomorium songaricum extractive has the anti-depression function, and can be effectively used for preparing the antidepressant drug, so that the application of the cynomorium songaricum extractive in the preparation of the antidepressant drug is realized.