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Application of rhizoma curculiginis extract in preparing anti-depression medicament

An extract and anti-depressant technology, applied in the field of medicine, can solve the problems of no public reports on the application of curculigo curculigo extract antidepressant drugs, no public reports on anti-depressant drugs of curculigo curculiosa, and achieve the development of medicinal value and preparation The method is simple and the effect of rich raw materials

Inactive Publication Date: 2014-10-08
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Along with the continuous improvement of Curculigo curculigo medicine value, the research to Curculigo curculigo is paid more and more attention to by people, but so far there is no public report on the application of Curculigo curculigo extract in the preparation of antidepressant drugs, and there is no preparation of Curculigo curculigo for treatment of depression. Public reporting of disease drugs

Method used

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  • Application of rhizoma curculiginis extract in preparing anti-depression medicament
  • Application of rhizoma curculiginis extract in preparing anti-depression medicament

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Embodiment Construction

[0006] The specific implementation of the present invention will be described in detail below in combination with specific situations.

[0007] In the specific implementation of the present invention, the application of curculigo curculigo extract in the preparation of antidepressant drugs, the curculigo curculigo extract is crushed into a coarse powder of 20-30 mesh sieve, with 10 times the weight of curculigo curculigo, Soak in ethanol with a volume concentration of 80% for 0.5h, reflux extraction twice, each time for 1.5h, filter, combine the filtrates, recover ethanol under reduced pressure until there is no alcohol smell, and concentrate to a concentrated solution with a relative density of 1.20-1.30 at 60°C , the concentrated solution is dispersed with distilled water to form a crude drug content of 0.5g / ml, and the dispersion is obtained. On the dispersion, the AB-8 type macroporous adsorption resin is applied. 1: 12; first elute with 4 times the column volume of distil...

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Abstract

The invention relates to application of a rhizoma curculiginis extract in preparing an anti-depression medicament, so as to effectively solve the problem of preparing anti-depression medicaments and realizing an application of a rhizoma curculiginis extract in preparing an anti-depression medicament. According to the application of the rhizoma curculiginis extract in preparing the anti-depression medicament, the rhizoma curculiginis extract is prepared by virtue of the following steps: crushing rhizoma curculiginis into coarse powder, soaking with ethanol, and performing reflux extraction; decompressing the filtrate to reclaim ethanol until the liquid does not have ethanol smell, concentrating, and dispersing the concentrate with distilled water to obtain a dispersant; loading the dispersant onto macroporous adsorption resin, eluting with distilled water, and removing the aqueous liquid; continuously eluting with ethanol, and removing the ethanol eluent; eluting with ethanol, collecting the ethanol eluent, reclaiming ethanol in reduced pressure, drying and crushing. The rhizoma curculiginis extract has an anti-depression effect and can be used for effectively preparing the anti-depression medicament, so that the application of the rhizoma curculiginis extract in preparing the anti-depression medicament can be realized.

Description

technical field [0001] The invention relates to medicine, in particular to the application of Curculigo curculigo extract in the preparation of antidepressant medicine. Background technique [0002] Curculigo orchioides (scientific name: Curculigo orchioides Gaertn.), also known as ground palm (Sichuan, Guizhou), monophyll (Sichuan), mountain codonopsis (Fujian), curculigo orchioides (Yunnan), Hainan ginseng (Hainan), Mao claw, Brahmin Ginseng belongs to Curculigoaceae, flowering period is from April to September. Medicinal plants have the functions of tonifying kidney and yang, benefiting essence and blood, strengthening muscles and bones, promoting blood circulation and reducing swelling. Along with the continuous improvement of Curculigo curculigo medicine value, the research to Curculigo curculigo is paid more and more attention to by people, but so far there is no public report on the application of Curculigo curculigo extract in the preparation of antidepressant drugs...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P25/24
Inventor 苗明三冯素香王灿
Owner HENAN UNIV OF CHINESE MEDICINE
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