Application of forsythia leaf extract to preparation of drug for treating mild diabetes

A technology of diabetes medicine and forsythia leaf, applied in the field of medicine, achieves the effects of simple preparation method, abundant raw materials, and significant economic and social benefits

Inactive Publication Date: 2017-11-28
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Treatment of warm heat, erysipelas, macule, carbuncle, scrofula, urinary stranguria; clinical application ① treatment of acute nephritis, ② treatment of purpura, ③ treatment of lung abscess, ④ treatment of retinal hemorrhage; but so far no forsythia Public reports on the application of leaf extracts in the preparation of drugs for the treatment of mild diabetes

Method used

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  • Application of forsythia leaf extract to preparation of drug for treating mild diabetes
  • Application of forsythia leaf extract to preparation of drug for treating mild diabetes
  • Application of forsythia leaf extract to preparation of drug for treating mild diabetes

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Embodiment Construction

[0007] Embodiments of the present invention will be described in detail below in combination with specific situations.

[0008] An application of the forsythia leaf extract as the only active ingredient in the preparation of medicines for treating mild diabetes. Forsythia leaf 10 times the weight of petroleum ether (30-60 ° C), reflux extraction for 1 hour, degreasing, discard the petroleum ether extract; Soak in 60% ethanol for 0.5h, reflux extraction for 1h, filter to obtain the first filtrate; add 10 times the weight of forsythia leaves and 60% ethanol to the dregs, reflux extraction for 1h, filter to obtain the second filtrate, combine The filtrate was collected twice, and the ethanol was recovered under reduced pressure until there was no alcohol smell, freeze-dried, and pulverized to obtain the forsythia leaf extract.

[0009] The invention has rich raw materials, simple preparation method, easy production and low cost. The forsythia leaf extract as the only active ingr...

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Abstract

The invention provides application of forsythia leaf extract to preparation of a drug for treating mild diabetes. Forsythia leaves are smashed into coarse powder, firstly petroleum ether (30-60 DEG C) is added, reflux extraction is conducted for 1 hour, degreasing is conducted, and a petroleum ether extracting solution is discarded; dry volatilization of the petroleum ether is conducted on forsythia leave medicine residue, ethyl alcohol is added and soaking is conducted for 0.5 hour, reflux extraction is conducted for 1 hour, filtering is conducted for two times, filter liquid is combined for two times, the ethyl alcohol is reclaimed till no alcohol taste exists, freezing, drying and smashing are conducted, and the forsythia leaf extract is obtained. According to the application of the forsythia leaf extract to preparation of the drug for treating the mild diabetes, raw materials are rich, the preparation method is simple, the cost is low, the drug is convenient to take, the forsythia leaf extract serves as the only active component, can be effectively used for treating the mild diabetes, the novel application and medical value of the forsythia leaves are developed, and the application of the forsythia leaf extract to preparation of the drug for treating the mild diabetes is a creation of the drug for treating the mild diabetes, and has significant economic and social benefits.

Description

technical field [0001] The invention relates to medicine, especially the application of forsythia leaf extract in the preparation of medicine for treating mild diabetes. Background technique [0002] diabetes It is a group of lifelong chronic hyperglycemia caused by multiple etiologies metabolic disease , long-term high blood sugar, damage to large blood vessels and microvessels and endanger the heart, brain, kidneys, peripheral nerves, eyes, feet, etc. According to the statistics of the World Health Organization, diabetes complications Up to more than 100 kinds, it is a disease with the most known complications. Clinical data show that about 10 years after the onset of diabetes, 30% to 40% of patients will have at least one complication, and once a complication occurs, drug treatment is difficult to reverse, and the fatality rate is often as high as 50%; [0003] Functions and indications of forsythia: heat clearing, detoxification, dissipating stagnation, detumescence...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61P3/10A61K127/00
CPCA61K36/634A61K2236/333A61K2236/35A61K2236/39A61K2236/51A61K2236/53
Inventor 苗明三苗艳艳许二平代丽萍
Owner HENAN UNIV OF CHINESE MEDICINE
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