The invention discloses a method for preparing cyclohexanone with a cyclohexane liquid-phase oxidation process. The method comprises processes including cyclohexane oxidation reaction solution synthesis, oxidation solution decomposition and washing, triple-effect alkane tower rectification, alkane four-tower rectification, twice saponification, coarse alcohol ketone continuous rectification and obtaining of cyclohexanone. The method is characterized in that the sequence of the processes is cyclohexane oxidation reaction solution synthesis, oxidation solution decomposition and washing, triple-effect alkane tower rectification, twice saponification, alkane four-tower rectification and coarse alcohol ketone continuous rectification to obtain cyclohexanone. The method can fully decompose cyclohexyl hydroperoxide, substantially reduce impurities such as aldehyde, ester and miscellaneous ketone in cyclohexanone, and improve the quality of cyclohexanone. The method has the advantages of simple process, low investment and cost, good separation effect and apparent impurity removal.