66 results about "Porphin" patented technology

The invention relates to a water-soluble molecular target porphin photosensitizer and a preparation method thereof. The photosensitizer is characterized in that the two bridged ends of polyethylene glycol (PEG) diamine are respectively connected with folic acid and porphin with substituent groups, wherein other substituent groups can be connected with the porphin, and the average molecular weight of PEG is 1000-10000. According to the preparation method of the water-soluble molecular target porphin photosensitizer, PEG diamine reacts with folic acid so as to produce PEG amine which is obtained from single folic acid, and the PEG amine has amidation with carboxyl, acyl chloride or anhydride substituent group on the porphin so as to obtain the porphin-PEG-folic acid target photosensitizer. The photosensitizer has good photodynamic activity, tumor target performance and good water solubility and is applicable to intravenous administration; the phagocytosis of macrophage to the photosensitizer can be reduced, the body circulation time of the photosensitizer is prolonged and the bioavailability of the photosensitizer is improved. Moreover, the preparation method of the water-soluble molecular target photosensitizer is simple to operate, has moderate conditions and has strong repeatability.

The invention provides a polyamide thin-layer composite reverse osmosis membrane as well as a preparation method and application thereof. The preparation method comprises the steps: preparing an ultrathin metal organic framework nanosheet zinc-meso-tetra(4-carboxyphenyl)porphin; ultrasonically dissolving the ultrathin metal organic framework nanosheet zinc-meso-tetra(4-carboxyphenyl)porphin in alcohol, performing filter pressing on a polyethersulfone ultrafiltration membrane through a filter pressing method to prepare an ultrathin middle layer, and soaking the composite membrane in a resorcinol aqueous solution and a n-hexane solution containing polybenzoyl chloride to form the polyamide thin-layer composite reverse osmosis membrane. The middle layer of the metal organic framework nanosheet can be used as a water permeation channel, so that the geometric resistance of water molecules infiltrating from a polyamide membrane to a polyether sulfone membrane is reduced, and the permeation rate of water in a polyamide thin-layer composite reverse osmosis membrane is increased; the ultrathin middle layer provides a good reaction container for formation of interfacial polymerization reaction, the surface area and crosslinking degree of the prepared polyamide membrane are increased, the internal thickness of the polyamide membrane is reduced, and the salt rejection rate is also improvedwhile the membrane flux is greatly increased.

The invention belongs to the technical field of energy materials, and relates to a preparation method and an application of a carbon cloth-based nickel-cobalt bimetal selenide nano square sheet electrode material. The preparation method comprises the following steps: adding a soluble cobalt salt, a soluble nickel salt, medium-tetra(4-carboxyphenyl)porphin and 4, 4 '-dipyridyl into an N, N-dimethylformamide and ethanol solution, carrying out ultrasonic uniform dispersion, carrying out a hydrothermal reaction with controllable temperature programming together with a carbon cloth substrate, and carrying out cleaning and drying to obtain a carbon cloth-based nickel-cobalt bimetal organic framework nano square sheet precursor; and putting selenium powder and the carbon cloth-based nickel-cobaltmetal organic framework nano square sheet precursor into a tubular furnace, and carrying out selenylation reaction to obtain a carbon cloth-based nickel-cobalt bimetal selenide nano square sheet electrode material. The metal selenide electrode material prepared by the invention has stable morphology, high specific surface area, more active sites, good mechanical stability, high conductivity, excellent electrochemical energy storage performance and electrochemical cycling stability.

The invention discloses a preparation method and application of a metalloporphyrin modified sulfur-doped reduced graphene oxide electrocatalyst. The preparation method comprises the following steps: (1) adding graphene oxide into a solvent, adding inorganic base and sulfonyl chloride, performing heating and stirring, removing the solvent after reaction, and performing washing, centrifuging, dryingand calcining to obtain sulfur-doped reduced graphene oxide; (2) adding porphin and metal salt into a solvent, and performing refluxing to obtain metalloporphyrin; (3) adding metalloporphyrin into the sulfur-doped reduced graphene oxide, carrying out ultrasonic treatment, transferring the mixture to an autoclave, and performing reacting, centrifuging, washing, and drying to obtain the metalloporphyrin-modified sulfur-doped reduced graphene oxide electrocatalyst. The application is as follows: the electrocatalyst is applied to cathode oxygen reduction reaction in a metal-air battery or a fuelcell. The electrocatalyst provided by the invention is good in catalytic performance, simple in preparation method and low in cost, and has important theoretical and practical significance for developing a novel electrochemical catalyst and an energy conversion and storage device.

The invention provides a chemical fiber containing organ-metallic catalyst. The weight ratio of the organ-metallic catalyst and the macromolecular compound which is nitrile, cellulose fiber, is (0.5-8): (92-99.5). The organ-metallic catalyst is the organic compound of the Fe, cobalt or manganese. a) phthalocyanine Fe, cobalt or manganese; b) porphyrin Fe, cobalt or manganese; c)porphin Fe, cobalt or manganese. The organ-metallic catalyst is dissolved in the spinning slurry, so to get the fibre by the wet spinning technology. The fiber is deodorant.

The present invention discloses one kind of branchy porphyrin molecule with the characteristics of intramolecular energy transfer and two-photon absorption, and features that the branchy porphyrin molecule is symmetric or asymmetric conjugated branchy molecule with porphin ring as core and triphenylamine element or carbazolyl radical as branch. The compound of the present invention has excellent optical performances, including strong two-photon absorption in both 532 nm and 800 nm bands and powerful up converting transmission in 650-750 nm band. It may be used in photodynamic treatment of two-photon absorption mechanism, light limitation in two-photon absorption mechanism and photovoltaic solar cell material.

The invention discloses a continuous production process of tetraaryl porphin. The process is as follows: firstly, adding a solvent into a multi-phase reaction separating synchronous reactor, wherein the reactor comprises a stirring reaction tower with a reflux device, and at least two constant-temperature settling towers communicated with the bottom of the stirring reaction tower, and the stirring reaction tower internally comprises a gas-phase region and a reaction region; during reaction, filling the solvent in the reaction region and the constant-temperature settling towers, adding reaction materials pyrrole and aromatic aldehyde into the stirring reaction tower to contact and react with inlet air when the temperature is increased to the reflux temperature of the solvent, directly settling the tetraaryl porphin generated by the reaction into the constant-temperature settling towers from the reaction region under gravity action until the constant-temperature settling tower are filled up with the tetraaryl porphin, and switching the stirring reaction tower to be communicated with the other constant-temperature settling tower filled up with the solvent, and carrying out the process alternatively to realize continuous production. The continuous production process disclosed by the invention can be used for continuously producing high-purity tetraaryl porphin with high yield and low cost.

The invention discloses an eco-friendly light-emitting hydrogel material containing a macrocyclic rare earth-terbium complex and a preparation method and application thereof. The eco-friendly light-emitting hydrogel material is TCPP / Tb / Alg. TCPP is tetrakis(4-carboxyphenyl)porphin, Tb is a rare earth terbium ion, Alg is sodium alginate and the material is in a form of hydrogel. In the hydrogel, the macrocyclic rare earth-terbium complex is connected to a sodium alginate network skeleton through covalent bonding. The decomposition temperature is 200 DEG C. The preparation method is carried outat the normal temperature under the normal pressure, utilizes cheap water as a solvent and is environment friendly. The material post-treatment is simple and easy. The hydrogel material has substantially no toxicity to rat thoracic aortic endothelial cells, good biocompatibility, and good recognition effects on transition metal ions and especially on Fe<3+> ions. The eco-friendly light-emitting hydrogel material can be used as a potential identification material for metal ions.

The invention discloses a continuous production process of tetraaryl metal porphyrin. The process is as follows: firstly, adding a solvent into a multi-phase reaction separation synchronous reactor, wherein the reactor comprises a stirring reaction tower with a reflux device, and at least two constant-temperature settling towers communicated with the bottom of the stirring reaction tower, and the stirring reaction tower comprises a gas-phase region and a reaction region; during reaction, filling the solvent in the reaction region and the constant-temperature settling towers, adding the reaction material tetraaryl porphyrin and a metal salt into the stirring reaction tower for stirring when a temperature is increased to reach a reflux temperature of the solvent or reacting under the condition of ventilating air, directly settling the tetraaryl metal porphyrin generated by the reaction under gravity action to enter the constant-temperature settling towers until the constant-temperature settling tower is filled up with the tetraaryl metal porphyrin, switching the stirring reaction tower to communicate with the other constant-temperature settling tower filled with the solvent and carrying out the process alternatively to realize continuous production. The continuous production process disclosed by the invention can continuously produce high-purity tetraaryl metal porphin with high yield and low cost.

The invention discloses a continuous production technology for tetra-aryl-bi-metal porphyrin. The continuous production technology is that a resolvent is fed into a heterogeneous reaction and separation synchronous reactor, wherein the reactor comprises a stirring reaction tower and at least two constant-temperature settling towers, the stirring reaction tower comprises a reflow device, the constant-temperature settling towers are communicated with the bottom of the stirring reaction tower, and the interior of the stirring reaction tower comprises a gas-phase area and a reaction area; during reaction, the reaction area and the constant-temperature settling towers are full of the resolvent, and reaction raw materials such as tetra-aryl-porphin and divalent metal salt are fed into the stirring reaction tower and react with air led into the stirring reaction tower when the reaction area and the constant-temperature settling towers are heated to the backflow temperature of the resolvent; the tetra-aryl-bi-metal porphyrin generated during the reaction settles directly under the actino of gravity and enters into a constant-temperature settling tower from the reaction area; when the constant-temperature settling tower is fully filled with the tetra-aryl-bi-metal porphyrin, the stirring reaction tower is switched to be communicated with the other constant-temperature settle tower fully filled with the resolvent; the steps are carried out alternately to ensure continuous production. The technology can be used for producing high-purity tetra-aryl-bi-metal porphyrin continuously with high yield and low cost.

The invention belongs to the field of nanobiomedicine diagnosis and treatment, and mainly relates to preparation of an organic / inorganic composite nano material system with high biocompatibility and application of the organic / inorganic composite nano material system in biological two-photon imaging and dual photosensitization dynamic therapy. According to the preparation disclosed by the invention, by adoption of an supramolecular self-assembling driver of a metal porphin complex, a functional metal-organic framework material ZnTPyP-MOF, so that the physical and chemical characteristics of an original assembling molecule ZnTPyP are retained, and the original assembling molecule ZnTPyP is endowed with new optical and structural characteristics. The MOF is used as a kernel for growing titanium oxide serving as a shell coated with a layer of polylysine, thus obtaining a high-performance two-photon diagnosis and treatment nano biological probe. The nano probe is high in biological safety and dispersity; and the ZnTPyP-MOF is high in two-photon absorption and fluorescence emission performance and realizes the photosensitization dynamic therapy under activation of two photons. The organic / inorganic composite nano material system can be widely applied to in-situ fluorescence diagnosis and treatment of various diseases, particularly the cancer, and has very important in clinical medicine.

The invention discloses a continuous production process of tetraaryl metal porphyrin. The process is as follows: firstly, adding a solvent into a multi-phase reaction separation synchronous reactor, wherein the reactor comprises a stirring reaction tower with a reflux device, and at least two constant-temperature settling towers communicated with the bottom of the stirring reaction tower, and the stirring reaction tower comprises a gas-phase region and a reaction region; during reaction, filling the solvent in the reaction region and the constant-temperature settling towers, adding the reaction material tetraaryl porphyrin and a metal salt into the stirring reaction tower for stirring when a temperature is increased to reach a reflux temperature of the solvent or reacting under the condition of ventilating air, directly settling the tetraaryl metal porphyrin generated by the reaction under gravity action to enter the constant-temperature settling towers until the constant-temperature settling tower is filled up with the tetraaryl metal porphyrin, switching the stirring reaction tower to communicate with the other constant-temperature settling tower filled with the solvent and carrying out the process alternatively to realize continuous production. The continuous production process disclosed by the invention can continuously produce high-purity tetraaryl metal porphin with high yield and low cost.

The invention provides an ultra-small nano metal organic framework material and a preparation method thereof. The MOFs material is prepared from a low-cost metal source and organic ligands through solvothermal reaction, wherein metal ions in the metal source are at least two of ferric ions, bivalent copper ions or bivalent zinc ions; the ligands are at least two of terephthalic acid, 2-aminoterephthalic acid, meso-tetra (4-carboxyphenyl) porphin, 2-nitroterephthalic acid, 2-hydroxyterephthalic acid and trimesic acid; the solvent is formed by mixing ethanol and o-dichlorobenzene according to the volume ratio of (1-3): 1. The particle size of the prepared MOFs material is 2-10 nm, and the prepared MOFs material is high in dispersity, specific surface area and activity. The MOFs material aqueous solution can generate a large amount of active oxygen in an ultrasonic environment, and has extremely high medical value.

The invention discloses a porphyrin-based metal-organic framework nanosphere as well as a preparation method and application thereof. The preparation method comprises the following steps: subjecting a mixed reaction system containing meso-tetra(4-carboxyphenyl)porphine and / or metal porphin, metal ions, an accelerant, an organic solvent and water to reacting at 50-130 DEG C for 1-5 hours to obtain a two-dimensional metal-organic framework structure micron sheet; and adding polyethyleneimine into a mixed reaction system obtained in the previous step, and carrying out a condensation reaction at 10-60 DEG C for 2-10 hours to obtain the porphyrin-based metal-organic framework nanosphere. According to the preparation method, the gauze-shaped micron large-size sheets are obtained by adjusting a ratio of porphin to metal ions, and then the porphyrin-based metal-organic framework nanosphere which is uniform in size and has coexisting micropores and mesopores are prepared through further reaction; and meanwhile, the porphyrin-based metal-organic framework nanosphere prepared by the method has wide application prospects in the fields of gas storage and separation, fuel cell performance conversion, biomedical imaging, cancer treatment and the like.

The invention discloses a method for continuously preparing tetraphenyl porphin. The method includes the following steps that 1, pyrrole and aromatic aldehyde are continuously added into a first reactor for conducting a reaction, and first reaction liquid is obtained; 2, the first reaction liquid obtained in step (1) and gas containing oxygen are continuously added into a second reactor for conducting a reaction, and second reaction liquid is obtained; 3, the second reaction liquid is cooled, crystallized, filtered and washed, and a tetraphenyl porphin product is obtained. The method has the advantages of being high in yield, high in reaction efficiency, low in energy consumption, safe, environmentally friendly and applicable to industrialization.

The invention discloses a modified diaphragm and a preparation method thereof and a lithium-sulfur battery, and belongs to the technical field of electrochemical new materials. The modified diaphragm is composed of a basic diaphragm and a composite material modified layer, and the composite material modified layer is formed by compounding a porphyrin-based MOF material and a conductive agent. The preparation method mainly comprises the following steps of preparing a composite material of Cu2TCPP-MOF and a conductive agent by taking meso-tetra (4-carboxyphenyl) porphin, copper nitrate trihydrate, the conductive agent such as graphene and a carbon nanotube as raw materials, and loading the composite material on the surface of the basic diaphragm through suction filtration to finally prepare the modified diaphragm. When the modified diaphragm prepared by the method is applied to the lithium-sulfur battery, the shuttle effect of the lithium-sulfur battery can be inhibited, and the specific capacity, the cycling stability and the rate capability of the battery are improved.

The invention relates to a novel porphin diether salt compound (I) as well as a preparation method and application thereof. The compound (namely, porphin diether disodium salt, porphin diether dimethyl salt, porphin diether dilithio salt and porphin diether diammonium salt compound) has a structure shown in the description. The compound provided by the invention has the advantages of single component, stable property, controllable quality, simple and convenient preparation method and high water solubility, and can be easily prepared into an injection or a freeze-drying preparation. The compound has remarkable photodynamic activity, and can be applied to photodynamic therapy of tumors, retina macular degeneration, actinic keratosis, nevus flammeus, verruca acuminate and the like.

The invention relates to a tetrahydroporphin compound and a preparation method and an application thereof. The structural formula of the compound is shown in the specifications. The preparation method comprises the following steps of: synthesizing 2,3-dihydro-2,3-di(dicyan methyl)-5,10,15,20-tetraphenyl porphin; synthesizing 2,3-dihydro-2,3-di(dicyan methyl)-12-nitro-5,10,15,20-tetraphenyl; synthesizing 2,3-cis-12,13-tetralin-2,3-di(dicyan)-[12:13]-[di(methoxycarbonyl group), di(cyan)methylene]-5,10,15,20-tetraphenyl; and synthesizing 2,3-cis-12,13-tetralin-2,3,12,13-(tetra-carboxymethyl)-5,10,15,20-tetraphenyl porphin. The tetrahydroporphin compound is applied to the preparation of a photosensitizer medicament for treating tumor diseases, and has a definite structure and a wide application prospect, and is easy to prepare.

The invention discloses preparation and application of a self-assembly-based porphyrin / alumina composite nano-channel film and belongs to the technical field of nanometer materials. The preparation method comprises the following steps: arranging a hourglass type alumina nano-channel film at a communication part of two tank bodies of self-made tanks so as to isolate electrolyte in the two tanks, wherein a TPPS (Tera(Sulfophenyl)Porphin) aqueous solution is filled in the tank on one side of the hourglass type alumina nano-channel film, and a sodium chloride aqueous solution is filled in the tankon the other side; simultaneously controlling modification time on the two sides, flushing with lots of ultrapure water after modification completion, and naturally airing, thereby obtaining the porphyrin / alumina composite nano-channel film. The porphyrin / alumina composite nano-channel film can be applied to ion transport and optical response. The preparation method disclosed by the invention hasthe advantages of being time-saving, easy to operate, low in cost and the like. A novel way for preparing the composite nano-channel film based on self-assembly is developed.

The invention discloses a preparation method of an electrochemical biosensor for detecting lead ions based on a rapid scanning cyclic voltammetry technology and application thereof. The preparation method is characterized by comprising the following steps: (1), preparing a magnetic amino functionalized multi-walled carbon nanotube mixed solution by adopting a traditional hydrothermal method; (2),adding tetra (4-carboxyphenyl) porphin into the magnetic amino functionalized multi-walled carbon nanotube mixed solution, and obtaining an NH2-MWCNTs@Fe3O4 / TCPP mixed solution through combination ofamino and carboxyl; (3), dropwise coating the surface of the pretreated magnetic glassy carbon electrode with the NH2-MWCNTs@Fe3O4 / TCPP mixed solution enriched with Pb <2+>; firmly absorbing the nanocomposite material on the surface of the electrode through the magnetic action, and completing the preparation of the electrochemical sensor by naturally airing at a room temperature. The electrochemical biosensor can be used in the application of detecting lead ions by a rapid scanning cyclic voltammetry technology, and has the advantages of high sensitivity, high selectivity and simple and rapidoperation.

The invention also discloses preparation of an electrochemical luminescence sensor capable of simultaneously detecting two kinds of sialylated glycans. According to the invention, a novel luminescentcomposite material Au (at) BSA MSs-Luminol and ZIF-8-TCPP are successfully prepared, and a potential resolution type electrochemical luminescence biosensor is developed for simultaneously detecting alpha2, 3-sialylated glycan and alpha2, 6-sialylated glycan. Luminol and meso-tetrakis (4-carboxyphenyl) porphin (TCPP) can emit optical signals at positive and negative potentials respectively. The formula (I) is shown in the specification. The bovine serum albumin doped gold microspheres (Au-BSA MSs) have a large number of active sites and excellent conductivity, and can be used for immobilizing more biological materials and remarkably improving luminol signals. Zeolite imidazolate skeleton-8 (ZIF-8) has a stable skeleton structure and a rough surface, and can provide more active sites for immobilizing biological materials and stabilize optical signals of meso-tetra (4-carboxyphenyl) porphin in an immobilization manner. Besides, based on the design of a magnetic capture probe 3-aminophenylboronic acid-magnetic microspheres (APBA-MMs), the construction process of the sensor is carried out in a solution, and compared with construction on an electrode, the sensor has a wider linear range.

The invention relates to a novel intermediate di(disubstituted) phenyl dihalogenated porphin derivative which is stable in performance, good in hydrophilicity and not prone to aggregation and an application thereof. The compound has the following structures (I) and (II), wherein X is Cl, Br or I; A and Y are the same or different and are independently CH2 or O; R1 and R2 are different, R3 and R4 are the same or different, at least one of R3 and R4 contains a polar group, and R3 and R4 are independently alkyl groups, alkyl groups containing N or O atoms, alkyl groups containing carbonyl groups or alkyl groups containing amido bonds or alkyl carboxylic acid, alkyl alcohol, alkyl carboxylic acid containing N or O atoms, alkyl alcohol containing N or O atoms, alkyl carboxylic acid containing carbonyl groups, alkyl alcohol containing carbonyl groups, alkyl carboxylic acid containing amido bonds, and alkyl carboxylic acid containing carbonyl groups and amido bonds at the same time. The prepared intermediate dihalogenated diphenyl porphin photosensitizer has remarkable photodynamic activity, and can be used as a drug for photodynamic diagnosis and treatment of diseases such as tumors, retina macular degeneration, actinic keratosis, nevus flammeus and condyloma acuminata.

The invention provides a preparation method of a sensitive element of a humidity sensor with a high-sensitivity humidity response characteristic. The preparation method comprises the following steps: by taking cobalt nitrate hexahydrate, 4, 4 '-dipyridyl, polyvinylpyrrolidone and meso-tetra (4-carboxyl phenyl) porphin as main raw materials, a cobalt-based metal organic framework Co-MOF is firstly obtained through a synthetic reaction; the Co-MOF and phytic acid are further subjected to a reaction, and a phytic acid modified Co-MOF material is obtained; the material and deionized water are mixed and ground into pasty slurry, the surface of a substrate and a sensitive material film are uniformly coated with the pasty slurry, and the phytic acid modified Co-MOF humidity sensor sensitive element is prepared after drying. The phytic acid and the Co-MOF material are complementary, the phytic acid can corrode free protons of an MOF framework, and the performance of the sensitive material is effectively regulated and controlled. The sensitive element of the humidity sensor is short in response time, wide in detected relative humidity range and good in stability.

The invention relates to the technical field of preparation of medicines for treating echinococcosis, and relates to a composition of a photodynamic combination drug and a preparation method and an application thereof. The composition comprises a photosensitizer or / and a chemical drug; wherein the photosensitizer is one or more of chlorin e6, viltipofen, indocyanine green, porphin sodium, 5-aminolevulinic acid, temopofen and talapofen, and the chemical drug is one or more of albendazole, albendazole sulfoxide, mebendazole, flubendazole, oxfendazole, artesunate, peganum harmala, tetrandrine andsophora japonica. According to the invention, through photodynamic therapy, the permeability of the hydatid and the hydatid cyst wall is increased; according to the invention, the target accumulationof chemotherapeutic drugs in the echinococcosis and the cyst wall is realized, the synergistic treatment effect is achieved, the resistance of the echinococcosis and the cyst to external drugs is reduced, the curative effect of the anti-echinococcosis drugs is improved, the administration dosage and the toxic and side effects of the drugs can be greatly reduced, and the application prospect in the preparation of echinococcosis treatment drugs is excellent.

A method for treatment of hyperproliferative tissue by injection of and subsequently exposing the hyperproliferative tissue to a frequency of ultrasound. The invention further includes purified bis [1-[6,7-bis [2-(sodium carbonate ethyl]-1,3,5,8,-tetramethyl-2-vinyl-porphin-4-yl]ethyl]ether (DVDMS) for use in sonodynamic treatment of hyperproliferative tissue including cancer and further includes a kit including a dosage controllable injection device charged with a biologically compatible fluid containing DVDMS.

The invention discloses a production method for tetraphenyl porphin. The production method includes the steps that 1, pyrrole and aromatic aldehyde are prepared into a mixed solution for standby application; 2, solvent is added into a polymerization reactor, the pressure of the polymerization reactor is maintained at 1-5 atm, the mixed solution obtained in the step 1 starts to be dripped to start a polymerization reaction, after the reaction is finished, reaction products are cooled to normal temperature, and filter liquor and a filter cake are obtained through filtration; 3, the filter cake obtained in the step 2 and propionic acid are added into an oxidation reactor, oxygen-containing gas is introduced to carry out an oxidation reaction, cooling is carried out after oxidation is finished, a solid and filter liquor are obtained through filtration, and the solid is washed and dried to obtain the tetraphenyl porphin. The production method has the advantages of being high in yield, safe and environmentally friendly, separation and purification are easy, and the production quality is stable.

The invention discloses an iron-based nano catalytic treatment reagent and a preparation method and application thereof, the iron-based nano catalytic treatment reagent comprises nanoparticles, and the nanoparticles are obtained by reaction of Fe metal ions, 6-thioguanine and Meso-tetra (4-carboxyphenyl) porphin according to a molar ratio of 2: 1: 1-3: 2: 2. The iron-based nano-catalytic treatment reagent prepared by a hydrothermal method is a nano-catalytic drug, shows relatively strong catalytic ability, and can catalyze hydrogen peroxide to generate oxygen and improve a hypoxic environment of tumors; meanwhile, the reagent has the properties of peroxidase mimicase and can be used for catalyzing the generation of highly oxidative hydroxyl radicals in cancer cells to induce apoptosis of the cancer cells, 6-thioguanine contained in the reagent can be used for tumor chemotherapy, and Meso-4-(4-carboxyphenyl) porphine can be used for tumor photodynamic therapy. the preparation method is simple and convenient, wide in raw material source, low in cost, repeatable and suitable for industrial production and application.

The invention relates to dihydro porphin E6 zinc bichloride photosensitizer and producing method and appliance. The dihydro porphin E6 zinc bichloride photosensitizer can be produced by importing the zinc atom into the dihydro porphin E6 and mixing the dihydro porphin E6 with the zinc bichloride in the ph>8 aqueous solution and affiliating the polyvinyl pyrrolidon solution. The dihydro porphin E6 zinc bichloride photosensitizer can be take orally or mainlined and has not the problem of the light sensitiveness to the skin. Besides, the dihydro porphin E6 zinc bichloride photosensitizer can be used for the local therapy by the laser apparatus activation or the head and ears cure by the low duty luminotron array apparatus (the light bed). The dihydro porphin E6 zinc bichloride photosensitizer is more practicable and safe compared with other photosensitizer, so the collectivity capability of the invention is excel other photosensitizer.

The invention provides a chemical fiber containing organ-metallic catalyst. The weight ratio of the organ-metallic catalyst and the macromolecular compound which is nitrile, cellulose fiber, is (0.5-8): (92-99.5). The organ-metallic catalyst is the organic compound of the Fe, cobalt or manganese. a) phthalocyanine Fe, cobalt or manganese; b) porphyrin Fe, cobalt or manganese; c)porphin Fe, cobalt or manganese. The organ-metallic catalyst is dissolved in the spinning slurry, so to get the fibre by the wet spinning technology. The fiber is deodorant.

The invention discloses application of a dihydrogen porphin titanium complex in preparation of a drug for treating tumor. Compared with dihydrogen porphin, the drug disclosed by the invention has a better treatment effect.