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48results about How to "Enhance photodynamic activity" patented technology
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Non-periphery substituted phthalocyanine metal complex and preparing method thereof
InactiveCN101012234ANot easy to gatherInhibit aggregationZinc organic compoundsOrganic solventFluorescence
The invention discloses several non-peripherial substituted phthalocyanine metal complexes and making method, which introduces functional group into position a (position 1(4), 8(11), 15(18) and 22(25)) of phthalocyanine complex.
Owner:FUZHOU UNIV
Use of non-periphery substituted phthalocyaniu metal complex
InactiveCN101023945ANot easy to gatherInhibit aggregationOrganic active ingredientsSenses disorderPhotodynamic therapyOrganic solvent
The present invention provides several application of non-peripheral substituted phthalocyanine metal coordination compound. The invented phthalocyanine metal coordination compound has the application for preparing photosensitive medicine preparation which can be used in photodynamic therapy or photodynamic diagnosis, and has the application for preparing photosensitizer which can be used in photodynamic purification or disinfection. Besides, it can be used as fluorescence probe or can be used for determining protein content.
Owner:FUZHOU UNIV
Phthalocyanine metal complex as well as preparation method and application thereof
ActiveCN104262350AHigh molar absorption coefficientGood spectral propertiesBiocideOrganic active ingredientsAntifungalPhotosens
The invention discloses a phthalocyanine metal complex as well as a preparation method and an application of the phthalocyanine metal complex. 3-[2,4,6-tri(dimethylamino methyl)-phenoxyl] phthalonitrile is prepared by using 2-phthalonitrile nitryl and 2,4,6-tri(dimethylamino methyl)-phenol as reactants, and further, the phthalocyanine metal complex substituted with amido or amido alpha bit is prepared. The phthalocyanine metal complex has the characteristics of high photosensitive activity and high water solubility; the phthalocyanine metal complex exists in water in a monomer mode, so that the photodynamic activity is facilitated in the water; the phthalocyanine metal complex is subjected to absorption spectroscopic redshift and shifted to a near-infrared area where is beneficial for penetrating through human tissues. The phthalocyanine metal complex is specially high in photodynamic antifungal activity and can be used for preparing photosensitizers or photodynamic medicines or photosensitive medicaments.
Owner:FUZHOU UNIV
Erlotinib-phthalocyanine conjugate as molecule-targeting anticancer photosensitizer
ActiveCN103341166AImprove targetingEnhance photodynamic activityEnergy modified materialsAntineoplastic agentsPhotosensErlotinib
The invention discloses an erlotinib-phthalocyanine conjugate as a molecule-targeting anticancer photosensitizer and its preparation method and use. Erlotinib structure units with alcoxyl long-chains are introduced to the periphery of a metal phthalocyanine large-ring so that amphipathy, biocompatibility and photosensitizer targeting are improved. The erlotinib-phthalocyanine conjugate is not aggregated easily, is conducive to cell uptake ratio improvement, has a single structure, has no isomers and can be purified easily. The erlotinib-phthalocyanine conjugate can improve photosensitizer targeting in photodynamic therapy and improve photosensitizer activity in photodynamic therapy. The preparation method has simple processes, less side reactions and a high yield, adopts easily available raw materials, has a low cost and is conducive to industrial production.
Owner:FUZHOU UNIV
Phthalocyanine-erlotinib yoke compound and preparation and application thereof
ActiveCN103288840AImprove targetingEnhance photodynamic activityOrganic chemistryEnergy modified materialsPhotodynamic therapyErlotinib
The invention discloses a molecular targeting anticancer photosensitizer phthalocyanine-erlotinib yoke compound, and preparation and application thereof. Erlotinib with a long alcoxyl chain is introduced at the periphery of a metal phthalocyanine ring, so that the amphipathy, the bioco mpatibility and the targeting effect of the photosensitizer can be increased. The yoke compound is not easily gathered, which is favorable for improvement of the cell uptake rate; meanwhile, since the compound is single in structure and no isomer exists, the product is easily purified. By adopting the compound, the targeting effect of the photosensitizer in photodynamic therapy is expected to be improved; and meanwhile, the activity of the photosensitizer in the photodynamic therapy is enhanced. The synthesis method of the phthalocyanine-erlotinib yoke compound is simple, involves less side reactions, is high in yield and low in cost; moreover, the raw materials are easily available. Therefore, industrial production is facilitated.
Owner:FUZHOU UNIV
Axial nucleoside asymmetrically-modified silicon phthalocyanine and preparation method and application thereof
ActiveCN103435639AGood amphipathyGood biocompatibilityAntibacterial agentsGroup 4/14 element organic compoundsPhotosensSilicon phthalocyanine
The invention discloses axial nucleoside asymmetrically-modified silicon phthalocyanine and a preparation method and application thereof, belonging to the preparation field of a photodynamic medicine or a photosensitizer. The axial nucleoside asymmetrically-modified silicon phthalocyanine disclosed by the invention can be applied to photodynamic treatment, photodynamic diagnosis or photodynamic disinfection as a photosensitizer, has the structural characteristic of axial asymmetric substitution, and shows good amphipathicity and excellent photodynamic activity.
Owner:FUZHOU UNIV
Ruthenium complex and nanometer silver composite hydrotalcite type nanometer material and preparation method and application thereof
ActiveCN106857656APhotodynamically activeEnhance photodynamic activityBiocideDead animal preservationReactive oxygen radicalsBiocompatibility Testing
The invention discloses a ruthenium complex and nanometer silver composite hydrotalcite type nanometer material and a preparation method and application thereof. The preparation method mainly comprises the following steps: firstly, intercalating the ruthenium complex between the hydrotalcite layers, and then adsorbing silver nano-particles on the surface of the hydrotalcite; the nanometer material has photodynamic activity due to the intercalated ruthenium complex, and is capable of producing active oxygen free radial after being motivated by corresponding wavelength optical for killing bacteria, and the light-emitting efficiency is further enhanced after the intercalation; the silver nano-particle loaded on the hydrotalcite surface not only has good sterilizing effect, but also can further enhance the photodynamic activity of the ruthenium complex. The nanometer material integrates multiple antibacterial organisms, has the features of high antibacterial activity, good biocompatibility and good stability. The preparation process of the material is simple, and the cost is low.
Owner:FUJIAN INST OF RES ON THE STRUCTURE OF MATTER CHINESE ACAD OF SCI
Phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as preparation method and application thereof
ActiveCN102659793AEasy to manufactureFast productionAntibacterial agentsSenses disorderPhotosensPharmaceutical drug
The invention discloses phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as a preparation method and application thereof, which belong to the field of the preparation of photodynamic medicines or photosensitizers. The phthalocyanine silicon modified by the amino ethyl groups and the phenoxy groups, which is provided by the invention, can be used as a photosensitizer for photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of definite composition, simple and convenient preparation, high photodynamic activity and the like, is easy to realize industrialization and has obvious economic and social benefits.
Owner:FUZHOU UNIV
Piperazine-modified phthalocyanine complex and preparation method thereof
InactiveCN103772397AEnhance amphipathicMaintain high photodynamic activityOrganic chemistryEnergy modified materialsBiocompatibility TestingSinglet oxygen
The invention discloses a piperazine-modified phthalocyanine complex as well as a preparation method and an application thereof. Piperazine molecules are introduced into the macrocyclic periphery of a metal phthalocyanine so as to enhance the amphipathy, the biocompatibility and the targeting of the phthalocyanine. A piperazine group contains two N atoms, so that after the synthesized phthalocyanine complex enters a tissue, if the tissue is normal, the single excitation state of the phthalocyanine can be quenched by lone pair electrons on the N atoms of the piperazine group under a light irradiation condition. Thus, the generation of singlet oxygen is avoided. If the tumor tissue is in a weak acid state, the N atoms are protonated, so that the single excitation state of the phthalocyanine cannot be quenched. Therefore, the singlet oxygen is generated so as to kill tumor cells. Based on the theory, the selectivity of the photodynamic therapy of the phthalocyanine is improved due to the introduction of the piperazine group, so that the damage of the phthalocyanine to the normal tissue is reduced. The piperazine-modified phthalocyanine complex has a single structure and does not contain isomers, and is easy to purify and low in cost, thereby being favorable for industrial production.
Owner:FUZHOU UNIV
Silicon phthalocyanine axially bonded with piperidine or morpholine derivative with ester bond
ActiveCN104650129AGood amphipathyStrong penetrating powerAntibacterial agentsGroup 4/14 element organic compoundsPhotosensMorpholine
The invention discloses a silicon phthalocyanine axially bonded with a piperidine or morpholine derivative with an ester bond as well as a preparation method and application of the silicon phthalocyanine and belongs to the field of preparing photodynamic drugs or photosensitizers. The silicon phthalocyanine can be used as a photosensitizer used for carrying out photodynamic antibacterium, photodynamic cancer resistance, photodynamically treating other diseases, photodynamic disinfection and photodynamic diagnosis and has the advantages of simple preparation, strong photosensitization and the like, and the maximum absorption spectrum is located in a near infrared region.
Owner:FUZHOU UNIV
Erlotinib-phthalocyanine conjugate and preparation method thereof
ActiveCN103304569ASingle structureEasy to purifyOrganic active ingredientsOrganic chemistryErlotinibChemical compound
The invention discloses an erlotinib-phthalocyanine conjugate which targets anti-cancer molecules, and a preparation method as well as an application of the erlotinib-phthalocyanine conjugate. Through introducing erlotinib with a long alcoxyl chain into the periphery of the metal phthalocyanine large ring, the amphipathy, the biocompatibility and the targeting of photo-sensitizer can be increased. The phthalocyanine conjugate is not easy to aggregate, which is beneficial for improving cell uptake rate; meanwhile, the compound is simple in structure and is free from isomer, and the product is easy to purify accordingly. By adopting the compound, the targeting of the photo-sensitizer in photo-dynamics therapy is helpful to be enhanced, and the activity of the photo-sensitizer in photo-dynamics therapy can be enhanced at the same time. As the synthetic method provided by the invention is simple, the side reaction is small, the yield is relatively high, the raw material is easily available and the cost is low, and the preparation method is beneficial for industrial production.
Owner:FUZHOU UNIV
Silicon phthalocyanine modified by cytidine derivative and preparation method and application thereof
ActiveCN102827228AEasy to manufactureFast productionAntibacterial agentsOrganic active ingredientsPhotosensPharmaceutical drug
The invention discloses silicon phthalocyanine modified by a cytidine derivative and a preparation method and an application thereof, which belong to the field of preparation of photodynamic medicaments or photosensitizers. The silicon phthalocyanine modified by the cytidine derivative provided by the invention can be taken as a photosensitizer for use in photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of high selectivity, high photodynamic activity and the like, has definite constitution, is easy and convenient to prepare, and is easy to be industrialized.
Owner:FUZHOU UNIV
Silicon phthalocyanine axially modified by aminoethyl phenoxyl and polyethylene glycol oligomer
ActiveCN103254223AGood amphipathyAsymmetric instead of uniqueAntibacterial agentsBiocidePhotosensOligomer
The invention discloses silicon phthalocyanine axially modified by aminoethyl phenoxyl and polyethylene glycol oligomer as well as a preparation method and application of silicon phthalocyanine, belonging to the field of preparation of photodynamic medicaments or photosensitizers. The silicon phthalocyanine provided by the invention can be used as a photosensitizer for photodynamic treatment, photodynamic diagnosis or photodynamic sterilization, has the structural characteristic of axially asymmetrical substitution and shows favorable amphipathy and extremely high photodynamic activity.
Owner:FUZHOU UNIV
Preparation method of hypocrellin-transferrin targeted drug delivery system and application of hypocrellin-transferrin targeted drug delivery system in photodynamic therapy
InactiveCN105617380AEasy to prepareMild conditionsOrganic active ingredientsPhotodynamic therapyHolo transferrinTumor target
The invention discloses a preparation method of a hypocrellin-transferrin targeted drug delivery system and an application of the hypocrellin-transferrin targeted drug delivery system in photodynamic therapy. The method comprises the following steps: with holo-transferrin as a carrier, inactivating the holo-transferrin by urea and beta-mercaptoethanol, and making a three-dimensional structure loose to expose Fe-ion coordination sites; adding excessive hypocrellin, coordinating with Fe coordination sites, eliminating uncombined HA and urea through dialysis, and restoring the three-dimensional structure of holo-transferrin with beta-mercaptoethanol, thereby obtaining the hypocrellin-transferrin targeted drug delivery system. The method is simple in preparation and good in application prospect; the hypocrellin-transferrin targeted drug delivery system can be prepared into freeze-dried powder for storage, and the freeze-dried powder is prepared into a preparation suitable for intravenous injection after being dissolved. Due to the tumor targeting action of holo-transferrin in the system, the photosensitive anti-tumor activity of hypocrellin can be significantly strengthened by the targeted drug delivery system.
Owner:NANJING NORMAL UNIVERSITY
Molecularly targeted aza aromatic ring axially substituted phthalocyanine complex and preparation method thereof
ActiveCN106243114ASingle structureEasy to purifySilicon organic compoundsEnergy modified materialsSynthesis methodsMorpholine
The invention discloses a molecularly targeted aza aromatic ring axially substituted phthalocyanine complex and a preparation method thereof. The molecular target drug N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholine-4-propoxy)quinazoline-4-amine with an alkoxy long chain is introduced to the axial direction of a phthalocyanine large ring so as to increase its amphipathy, biocompatibility and photosensitizer targeting. The compound has the advantages of single structure, definite composition, no isomer, and easy product purification, also the complex is not easy to gather, thus being conducive to increasing the cell uptake rate. The synthesis method of the complex provided by the invention is simple, and has the characteristics of few side reaction, easily available raw materials, and low cost, and is in favor of industrial production.
Owner:FUZHOU UNIV
Phthalocyanine metal complex containing piperazine ethyoxyl modification group and preparing method thereof
ActiveCN102675325AGood amphipathyEasy to manufactureAntibacterial agentsOrganic active ingredientsPhotosensPharmaceutical drug
The invention discloses a phthalocyanine metal complex containing piperazine ethyoxyl modification group and a preparing method thereof and belongs to the field of photodynamic drug preparing or photosensitizer preparing. The phthalocyanine metal complex containing piperazine ethyoxyl modification group is characterized in that the phthalocyanine metal complex has amphipathy and absorbs and sends spectrums to the wavelength position where the spectrums can pierce through human tissues in red shift mode, and photosensitizer is high in reactive oxygen production capacity. The preparing method is simple and has remarkable economic effect and social effect.
Owner:FUZHOU UNIV
Silicon phthalocyanine modified by adenosine derivative and preparation method and application thereof
ActiveCN102827227AEasy to manufactureFast productionAntibacterial agentsOrganic active ingredientsPhotosensAdenosine
The invention discloses silicon phthalocyanine modified by an adenosine derivative and a preparation method and an application thereof, which belong to the field of preparation of photodynamic medicaments or photosensitizers. The silicon phthalocyanine modified by the adenosine derivative provided by the invention can be taken as a photosensitizer for use in photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of high selectivity, high photodynamic activity and the like, has definite constitution, is easy and convenient to prepare, and is easy to be industrialized.
Owner:FUZHOU UNIV
Nanocomposite material with reinforced photodynamic activity and preparation method thereof
ActiveCN108485644APromote crystallizationHigh luminous intensityMaterial nanotechnologyPhotodynamic therapyPhotodynamic therapyNano composites
The invention provides a nanocomposite material with reinforced photodynamic activity and a preparation method thereof. The nanocomposite material is an up-converting nanocrystal @SiO2@TiO2 / Au, and iscomposed of an up-converting nanocrystal, SiO2 and TiO2 shells successively coated at the periphery of the up-converting nanocrystal, and Au nanoparticles deposited on the surface of the TiO2 shell,wherein the TiO2 shell is a porous TiO2 shell composed of nanoparticles; the nanocomposite material has a particle size of 40 to 98 nm; and the particle size of the Au nanoparticles is 3.0 to 20.2 nm.The preparation method comprises the following steps: (1) coating the TiO2 shell onto a SiO2 coated up-converting nanocrystal through a controlled hydrolysis method; and (2) loading the Au nanoparticles onto the surface of TiO2 through a photochemical method. The nanocomposite material provided by the invention has the following advantages: simple and highly-efficient preparation process, uniformproduct morphology, good controllability in constitution and sizes, strong ability of generating reactive oxygen species, excellent photodynamic activity, and good application prospect in the field of photodynamic therapy.
Owner:ZHEJIANG NORMAL UNIVERSITY
Novel tetrapyrrole derivative and application thereof
PendingCN113831351AEasy to makeEnhance photodynamic activitySenses disorderOrganic chemistryMacula lutea degenerationCarboxylic acid
The invention relates to a novel intermediate di(disubstituted) phenyl dihalogenated porphin derivative which is stable in performance, good in hydrophilicity and not prone to aggregation and an application thereof. The compound has the following structures (I) and (II), wherein X is Cl, Br or I; A and Y are the same or different and are independently CH2 or O; R1 and R2 are different, R3 and R4 are the same or different, at least one of R3 and R4 contains a polar group, and R3 and R4 are independently alkyl groups, alkyl groups containing N or O atoms, alkyl groups containing carbonyl groups or alkyl groups containing amido bonds or alkyl carboxylic acid, alkyl alcohol, alkyl carboxylic acid containing N or O atoms, alkyl alcohol containing N or O atoms, alkyl carboxylic acid containing carbonyl groups, alkyl alcohol containing carbonyl groups, alkyl carboxylic acid containing amido bonds, and alkyl carboxylic acid containing carbonyl groups and amido bonds at the same time. The prepared intermediate dihalogenated diphenyl porphin photosensitizer has remarkable photodynamic activity, and can be used as a drug for photodynamic diagnosis and treatment of diseases such as tumors, retina macular degeneration, actinic keratosis, nevus flammeus and condyloma acuminata.
Owner:SHANGHAI XIANHUI MEDICAL TECH
Silicon phthalocyanine axially modified by aminoethyl phenoxyl and polyethylene glycol oligomer
ActiveCN103254223BGood amphipathyAsymmetric instead of uniqueAntibacterial agentsBiocidePhotosensOligomer
Owner:FUZHOU UNIV
A Molecularly Targeted Anticancer Photosensitizer Erlotinib-Phthalocyanine Conjugate
ActiveCN104447769BImprove targetingEnhance photodynamic activityOrganic chemistryEnergy modified materialsPhotodynamic therapyErlotinib
The invention discloses a molecularly targeted anticancer photosensitizer erlotinib-phthalocyanine conjugate and application thereof. An erlotinib structural unit with a long alkoxy chain is introduced into the periphery of a metal phthalocyanine big ring, so that the amphipathicity, biocompatibility and targeting property of the photosensitizer can be improved. The conjugate is difficult to aggregate, and the cellular uptake ratio is improved; and meanwhile, the compounds are simple in structure, an isomer does not exist, and the product is easy to purify. According to the compound, the targeting property of the photosensitizer in photodynamics therapy is expected to be improved, and the activity of the photosensitizer in photodynamics therapy is enhanced. The synthetic method is simple, fewer side reactions are carried out, the yield is high, the raw materials are readily available, the cost is low, and the industrial production is realized.
Owner:FUZHOU UNIV
Ortho-positioned bridged azacrown ether modified phthalocyanin and preparation method and application thereof
ActiveCN103304579AUnique structural featuresClear structureAntibacterial agentsOrganic active ingredientsOrtho positionChemical compound
The invention discloses a ortho-positioned bridged azacrown ether modified phthalocyanin, and a preparation method and application thereof, and belongs to the field of optically functional material preparation. The compound provided by the invention has unique ortho-positioned bridged azacrown ether modification characteristic, and is clear in structure and unique in synthesis route. The compound provided by the invention is a multifunctional molecule which can be taken as both a photosensitive drug and a metal ion spectrum probe. As the photosensitive drug, the photosensitization ability of the compound is high; and as the spectrum probe, the compound can be used for selective identification to Fe<3+> and Cu<2+> ions.
Owner:FUZHOU UNIV
A kind of targeted anticancer molecule gefitinib phthalocyanine conjugate and its preparation and application
ActiveCN103626781BImprove targetingEnhance photodynamic activityGroup 4/14 element organic compoundsEnergy modified materialsPhotosensChemical compound
Owner:FUZHOU UNIV
A silicon phthalocyanine with an axial ester bond linking piperidine or morpholine derivatives
ActiveCN104650129BGood amphipathyStrong penetrating powerAntibacterial agentsGroup 4/14 element organic compoundsDiseaseMorpholine
The invention discloses a silicon phthalocyanine axially bonded with a piperidine or morpholine derivative with an ester bond as well as a preparation method and application of the silicon phthalocyanine and belongs to the field of preparing photodynamic drugs or photosensitizers. The silicon phthalocyanine can be used as a photosensitizer used for carrying out photodynamic antibacterium, photodynamic cancer resistance, photodynamically treating other diseases, photodynamic disinfection and photodynamic diagnosis and has the advantages of simple preparation, strong photosensitization and the like, and the maximum absorption spectrum is located in a near infrared region.
Owner:FUZHOU UNIV
A kind of axial nucleoside asymmetrically modified silicon phthalocyanine and its preparation method and application
ActiveCN103435639BGood amphipathyGood biocompatibilityAntibacterial agentsGroup 4/14 element organic compoundsPhotosensPharmaceutical drug
The invention discloses a silicon phthalocyanine asymmetrically modified by axial nucleosides, a preparation method and application thereof, and belongs to the field of preparation of photodynamic drugs or photosensitizers. The axial nucleoside asymmetrically modified silicon phthalocyanine provided by the present invention can be used as a photosensitizer for photodynamic therapy, photodynamic diagnosis or photodynamic disinfection. It has the structural characteristics of axial asymmetric substitution and shows good amphiphile and high photodynamic activity.
Owner:FUZHOU UNIV
Non-periphery substituted phthalocyanine metal complex and preparing method thereof
InactiveCN101012234BNot easy to gatherInhibit aggregationZinc organic compoundsOrganosolvPhthalocyanine
The invention discloses several non-peripherial substituted phthalocyanine metal complexes and making method, which introduces functional group into position a (position 1(4), 8(11), 15(18) and 22(25)) of phthalocyanine complex.
Owner:FUZHOU UNIV
Use of non-periphery substituted phthalocyaniu metal complex
InactiveCN101023945BNot easy to gatherInhibit aggregationOrganic active ingredientsSenses disorderPhotodynamic therapyPhotosensitizer
Owner:FUZHOU UNIV
Phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as preparation method and application thereof
ActiveCN102659793BEasy to manufactureFast productionAntibacterial agentsSenses disorderPhotosensPharmaceutical drug
The invention discloses phthalocyanine silicon modified by amino ethyl groups and phenoxy groups as well as a preparation method and application thereof, which belong to the field of the preparation of photodynamic medicines or photosensitizers. The phthalocyanine silicon modified by the amino ethyl groups and the phenoxy groups, which is provided by the invention, can be used as a photosensitizer for photodynamic therapy, photodynamic diagnosis or photodynamic disinfection, has the advantages of definite composition, simple and convenient preparation, high photodynamic activity and the like, is easy to realize industrialization and has obvious economic and social benefits.
Owner:FUZHOU UNIV
A kind of erlotinib-phthalocyanine conjugate and preparation method thereof
ActiveCN103304569BImprove targetingEnhance photodynamic activityOrganic active ingredientsOrganic chemistryErlotinibPhotosensitizer
Owner:FUZHOU UNIV
Thermally activated delayed fluorescent polymer and application thereof
PendingCN114031754AHigh fluorescence quantum efficiencyEnhance photodynamic activityAntibacterial agentsPhotodynamic therapyBenzeneAnthracene
The invention discloses a thermally activated delayed fluorescent polymer and application thereof. In the general formula of the thermally activated delayed fluorescent polymer, X represents a connection mode between a benzene ring A and a benzene ring B, and the connection mode comprises that the benzene ring A and the benzene ring B are connected without X, connection is achieved by a single bond, and connection is achieved through any one of -NR1-, -O- and -S-, m+n=0.5, and m is greater than 0 and greater than 0.5. AR1 is substituted benzene, naphthalene, fluorene, carbazole, spirofluorene, anthracene and xanthene, and the substitution on the AR1 is one of a C1-C20 straight chain substituent group, a C1-C20 branched chain substituent group, a C1-C20 straight chain alkoxy group or a C1-C20 branched chain alkoxy group. According to the technical scheme, the advantages of high fluorescence quantum efficiency, relatively long emission wavelength, high photodynamic activity and the like are obtained through a simple synthesis means, and the compound can be used as an active component of a nano reagent for biomedical application.
Owner:NANJING UNIV OF POSTS & TELECOMM
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