The invention discloses an application of injectable hydrogel in preparing intraocular
filling materials. The application is characterized by being application of the injectable hydrogel as intraocular
filling materials in vitreoretinal
surgery as well as application of the injectable hydrogel as an intraocular
drug carrier, wherein the injectable hydrogel is composed of two agents; the first agent is a glue solution containing oxidized
polysaccharide; the second agent is a glue solution containing a
chitin derivative and / or collagen; the two agents are separately contained in two injection tubes of a duplicate
injector; the two glue solutions are simultaneously pushed and injected by the duplicate
injector; in the pushing and injecting process, mixing and cross-linking are generated, namely, a dialdehyde group of the oxidized
polysaccharide generates cross-linking reaction with amino of the
chitin derivative and / or the collagen to form hydrogel with
viscoelasticity. The constituents of the hydrogel are biomacromolecules different from chemical macromolecules, and a micromolecule cross-linking agent is not introduced, so that the
biocompatibility is good, the hydrogel can be degraded and absorbed, toxic and side effects are avoided, and the safety is good.