30 results about "Bergapten" patented technology

The invention relates to novel bacterial QS (quorum sensing) inhibitors and an antibacterial application thereof. Two coumarin compounds including psoralen and bergapten are obtained through separation and identification from fig leaves. Experiments prove for the first time that the compounds have activity of inhibiting Chromobacterium violaceum and pseudomonas aeruginosa QS systems and cannot produce survival pressure to pathogenic bacteria which further produce drug resistance, thereby being novel antibacterial compounds. The novel bacterial QS inhibitors and the antibacterial application thereof have the advantages that raw materials are easily available, a preparation method is easy to implement, and drug resistance and toxic actions are avoided, so that the coumarin compounds have potential to be developed into lead compounds for novel antibacterial drugs.

The invention discloses medicine for the treatment of spleen insufficiency damp-aggregating type chloasma and a preparation method thereof. The medicine for the treatment of spleen insufficiency damp-aggregating type chloasma is composed of medicine for oral use and medicine for external use, wherein the medicine for oral use comprises asparagus, ginseng, astragalus, poria cocos, polyporus umbellatus, atractylodes macrocephala koidz, rhizoma alismatis, liquidambar formosana hance, oroxylum indicum vent, rhizoma cimicifugae, rhizoma cimicifugae, chaenomeles sinensis koehne, rhizoma atractylodis, semen lablab album, bilobate grewia, marrow honey-suckle, sculpins, medicated leaven and wild angelica dahurica; the medicine for external use comprises powder on the surface of a dried persimmon, katsumade galangal seeds, costusroots, citrus, pericarpium arecae, cortex mori radicis, ginger peel, perilla leaves, radix platycodi, radix cyathulae, feather cockscomb seed, butterflybush flower, rice-grain sprout, rhizoma nardostachyos, snow pears, illigera cordata rootss, berchemia sinica, bergapten and nakedflower beautyberry branchlet and leaves. The medicine for the treatment of spleen insufficiency damp-aggregating type chloasma and the preparation method thereof have the advantages that the medicine for the treatment of spleen insufficiency damp-aggregating type chloasma has effects on tonifying the spleen and supplementing qi, clearing damp and removing chloasma, regulating the middle warmer and resolving damp, soothing the liver and harmonizing the stomach, clearing damp and promoting dieresis, warming yang, eliminating water and glorifying the face, activating collateral and removing chloasma, and promoting blood circulation to remove blood stasis, and the main function is the treatment of the spleen insufficiency damp-aggregating type chloasma; the treatment effect is good, the toxic and side effects are small, and the spleen insufficiency damp-aggregating type chloasma is not prone to reoccurring.

The present invention provides laminaria japonica sugar and a preparation method thereof. The laminaria japonica sugar is prepared from laminaria japonica, celery, carrots, pumpkins, orange peels, dragon fruit peels, citrus fruit juice and mango juice as raw materials. The laminaria japonica has characteristics of being low in calorie, moderate in proteins and high in minerals; the celery is rich nutrition, and the stems and leaves contain apiin, bergapten, organic acids, carotene, vitamin C, carbohydrates, and volatile oil containing a special smell of butylphthalide derivatives; the carrots are rich in vitamins, can stimulate skin metabolism, and can enable the skin to be delicate and smooth; and the pumpkins contain human body beneficial ingredients of polysaccharides, amino acids, active protein carotenoids, a variety of trace elements, etc. Therefore, the prepared laminaria japonica sugar is rich in nutrient, improves and expands the nutritional efficacies of the laminaria japonica, and is liable to be absorbed by human body, convenient to eat and carry, and good in taste.

The invention discloses a medicine composition for pre-operative regulation of pelvic abscess and a preparation method thereof. The medicine composition is mainly prepared from triamterene, tinidazole, ursolic acid, aucubin, luteolin, chlorogenic acid, total glucoside of paeony, polygalic acid, glutathione powder, tribulus terrestris saponins superfine powder, mangiferin, bergapten, amino acid and mannitol. The medicine composition is prepared from multiple effective ingredients in a reasonable proportion, has the effects of diminishing inflammation, inhibiting bacteria, diminishing swelling, eliminating pus, clearing heat, removing dampness, enhancing body immunity and regulating physical constitution, and is used for providing pre-operative assistant treatment for pelvic abscess patients requiring operating treatment, so that on the one hand, patient pain can be alleviated and symptoms can be reduced, and on the other hand, the probability of infection during the operation can be reduced, the operation difficulty can be reduced in an assistant way, and thus a good operation effect can be achieved.

The invention discloses application of bergapten in treatment of depression, and belongs to the technical field of medicines. The invention provides a natural medicine bergapten for preventing and treating depression by regulating inflammatory response for the first time, and the depression symptom is remarkably improved. The bergapten enables the immobility time of lipopolysaccharide (LPS)-induced anti-depression mice in a tail suspension test and a forced swimming test to be obviously reduced; the sweet water preference percentage is increased, and the autonomous activity is enhanced; and the action mechanism is related to the neuroinflammatory response mediated by the activation of depression mouse microglial cells. The invention provides a new way for improving the current depression treatment method. According to the scheme, new use of old medicines can be realized, and the time from medicine discovery to clinical transformation can be greatly shortened.

The invention provides a pharmaceutical composition which comprises an effective dose of bergapten and pharmaceutically acceptable carriers or excipients, and the pharmaceutical composition can be used for preventing and / or treating bone loss.