109results about How to "Overcoming selectivity" patented technology

The invention discloses a magnetic resonance imaging nanometer drug carrier, and a nanometer drug loading system and a preparation method thereof. The magnetic resonance imaging nanometer drug carrieris a triblock polymer nanoparticle, wherein the triblock polymer is PLGA-PEI-PEG, and has active groups on the surface, and the active groups comprise amino, hydroxyl and carboxyl. According to the present invention, the drug carrier can efficiently load a nuclear magnetic resonance imaging drug and an antitumor drug to make the antitumor drug specifically reach the tumor lesion site, such that the nuclear magnetic resonance positioning of the superparamagnetic ferroferric oxide nanoparticle at the tumor region can be achieved while the high-selectivity and low-toxicity treatment effect can be achieved, and the disadvantages of poor selectivity, strong toxic-side effect, easy drug-resistance generation and the like of the traditional cytotoxic drugs can be overcome; and the preparation method is simple and is easy to perform, the prepared triblock polymer nanoparticle can be stably stored in the aqueous solution so as to be easily stored, and various functional groups exist on the surface of the particle, such that the prepared triblock polymer nanoparticle can be easily subjected to surface modification or surface functionalization.

The invention discloses a catalytic conversion method which belongs to the technical field of catalytic conversion of petrolic alkanes. The catalytic conversion is carried out in a first reaction system and a second reaction system sequentially; after raw oil enters the first reaction system for catalytic reaction, all or part of the produced fractions enter the second reaction system in gaseous state and / or liquid state for further catalytic reaction; the first reaction system and the second reaction system respectively use a corresponding catalyst according to different reaction raw materials and target products. By using two reaction systems, the method of the invention using pertinence catalysts to carry out selective catalytic conversion of different fractions, overcomes the deficiencies of poor selectivity and low adjuvant content, and diluting the catalyst when adopting single catalyst, can enhance the productivity of chemical raw materials such as low carbon alkene, etc. and enhance the yield of products; the method overcomes the shortcoming of large energy consumption for cooling and preheating and saves investment, thus greatly enhancing the economical efficiency.

The invention discloses a silicon micro-condenser microphone chip, which comprises a silicon substrate with a perforated back board on top. Wherein, the said back board comprises a continual doping layer on top of said substrate with a plurality of acoustics holes by etching the continual doping layer or also a silicon material layer under the doping layer. This invention overcomes the problem to prepare back board and perforation with deep-selective enriched boron, and provides a simple and practical technique for industrial production.

The invention relates to a catalyst for preparing propylene through C4 olefin cracking, and a preparation method thereof. The problems of low stability and low propylene selectivity of present catalysts for preparing propylene through present C4 olefin cracking are mainly solved. The catalyst comprises 20-90% of ZSM-5 molecular sieve with the shape index of 3-100 (the shape index is defined as a length ratio of a longest edge to a shortest edge of a molecular sieve crystal in a three dimensional direction), 0.05-3% of a transition metal oxide and 18-69% of a binder. The catalyst provided by the invention well solves the problems, and can be used in the industrial production for preparing propylene through C4 olefin cracking.

The invention relates to a power-system direct current power transmission line relay protection field and especially relates to a single-terminal electric-quantity whole-line quick action protection method which can be used to identify faults in and out of an HVDC transmission line area. An amplitude of a specific frequency component in a single-terminal direct-current filter branch is used to realize discrimination of the faults in and out of the area. The method of the invention is used to protect a single-terminal whole-line quick action in the direct current power transmission line of the power system. The protection can be achieved only by using the single-terminal electric quantity. The method has a low requirement to a sampling frequency. An algorithm is simple. Sensitivity is high. The method can be realized during engineering. The action speed is fast, selectivity is good and reliability is high. A theory is completed and is easy to be adjusted. The protection method of the invention can replace current traveling-wave protection which is taken as the main protection of the direct current power transmission line. And the method is especially suitable for realizing the whole-line quick action protection of the ultra / super HVDC power transmission line by using the single-terminal electric quantity.

The invention relates to a combined water purifying device and method. The combined water purifying device comprises an ozone generating and exhaust treating system, a catalytic filter system, a post-treatment effluent collecting system and a gas-water alternate operation control system, wherein the ozone generating and exhaust treating system is connected to the catalytic filter system; and the gas-water alternate operation control system is sued for controlling the operation of the combined water purifying device. The combined water purifying device provided by the invention is compact in structure and small in floor area, and can be automatically controlled and upgraded. The combined water purifying method provided by the invention integrates ozone catalytic oxidation, bubbleless aeration and membrane filtration. Raw water is subjected to coagulating sedimentation and then flows into a catalytic filter tank; a membrane assembly is immersed below a liquid level; ozone is introduced into the membrane assembly to carry out bubbleless aeration; purified water is filtered and enters into the membrane assembly; and exhaust generated by the catalytic filter system enters into an exhaust breaking device to break ozone. The combined water purifying method provided by the invention can effectively treat relatively trace refractory organics in a water body, and deeply purifies micro-polluted water body.

The invention relates to a preparation method for a black-silicon poly-silicon PERC cell structure with a selective emitter. The preparation method is characterized by comprising the following steps of (1) forming a nanometer texturing surface on a front surface of a silicon wafer, wherein a back surface is a polishing surface; (2) performing front-surface diffusion of the silicon wafer to form anN-type layer, and removing front-surface phosphorosilicate glass and a back-surface pn junction; (3) depositing a silicon nitride anti-reflection film layer on the front surface of the silicon wafer,and depositing a passivation dielectric layer on the back surface; (4) dotting or routing the back surface of the silicon wafer, and printing a silver electrode and aluminum paste; (5) performing low-temperature sintering to form a local aluminum back field; (6) spraying a mixed solution of phosphoric acid and alcohol on the front surface of the silicon wafer, and forming a main grid line regionand a secondary grid line region after heavy doping by laser; and (7) immersing the front surface of the silicon wafer in an electroplating solution, electroplating the front surface of the silicon wafer under an illumination condition, and annealing after electroplating. By the preparation method, the defects that a high-quality fine grid line is difficult to form by silk-screen printing and thegrid line and a selective emitter cannot be enabled to be accurately aligned are overcome, and shielding and leakage current caused by an electrode are minimum.

The invention relates to the application of high-positive-charge green fluorescent protein (GFP) in the research of glycosaminoglycans (GAGs), wherein the amino acid sequence of the high-positive-charge fluorescent protein is as shown in SEQ ID No. 1. According to the application of the high-positive-charge GFP, the high-positive-charge GFP is taken as a fluorescent probe with biocompatibility, high sensitivity and high selectivity for the first time and is applied to the visualization of the GAGs on the surface of a living cell, the high selectivity quantitative analysis of the GAGs in serum, the pollution analysis of excessively sulfated chondroitin sulfate in heparin, etc. Therefore, the defects that the traditional cationic dye is poor in biocompatibility, low in selectivity, low in sensitivity and the like in the detection of the GAGs can be overcome; the high-positive-charge GFP has important application value and can be widely applied to basic and application study, clinical diagnosis, detection of medicines and food, and the like which are related to the GAGs.

The invention discloses a litsea cubeba oil based preservative and fresh-keeping composition. The composition comprises the following components in parts by weight: 10-20 parts of plant essential oil composite, 20-30 parts of surfactant, 20-30 parts of cosurfactant, and 25-60 parts of distilled water; and the plant essential oil composite comprises the following components in parts by weight: 40-60 parts of litsea cubeba oil, 20-40 parts of eucalyptus oil, and 20-40 parts of curcuma oil.

The invention relates to a binderless ZSM-5 / beta symbiotic molecular sieve catalyst and a preparation method thereof. The binderless ZSM-5 / beta symbiotic molecular sieve catalyst is mainly used for solving the problems in the prior art that the activity is relatively low when the prepared ZSM-5 / beta symbiotic zeolite molecular sieves contain binders and the strength is relatively poor when the prepared ZSM-5 / beta symbiotic zeolite molecular sieves do not contain the binders. According to the binderless ZSM-5 / beta symbiotic molecular sieve catalyst and the preparation method thereof, through adopting the technical scheme of firstly carrying out mixed shaping on silicon and aluminum raw materials, then, converting the silicon and aluminum raw materials into ZSM-5 and beta zeolite molecular sieves with the shape index of 3-100 by using a mixed aqueous solution of organic amine and organic quaternary ammonium base, and carrying out modification, thereby forming the binderless ZSM-5 / beta symbiotic zeolite molecular sieve catalyst; the problems are better solved, and the prepared binderless ZSM-5 / beta symbiotic molecular sieve catalyst with the shape index of 3-100 can be applied to the industrial production of preparing propene through cracking alkenes.

The invention relates to a preparation method of oxidized nano bacteria cellulose, belonging to the related fields of biomedical materials and medical appliances. The method comprises the following steps: performing pretreatment and purification treatment on nano bacteria cellulose film to obtain purified nano bacteria cellulose, and shearing into wafers or square slices of different specifications; placing sheared nano bacteria cellulose in a clean wide-necked bottle or a wide-necked bottle holding a nitric acid solution with appointed concentration, and introducing NO2 / N2O4 gas generated by reaction between copper powder and concentrated nitric acid to the wide-necked bottle so as to oxidize the nano bacteria cellulose; and taking out the sample after appointed time, and repeatedly cleaning with deionized water to obtain oxidized nano bacteria cellulose containing carboxyl group on C6 position. The prepared oxidized nano bacteria cellulose has excellent degradation property, biocompatibility and cellular affinity, excellent bleeding arresting performance and mechanical properties, and excellent water permeation, gas permeation, guiding and moisture absorption effects, and has higher application value in the aspects of implantation materials and wound bleeding arresting materials.

The present invention relates to color developing culture medium, detecting kit and detection method for Vibrio parahaemolyticus, and belongs to the field of food microbe safety monitoring technology. The detecting kit consists of color developing culture medium comprising bacterial specific enzyme in 0.05-0.95 g and mixed color developing substrate Y-glucoside, enrichment liquid A of pancreatic casitone liquid culture medium and enrichment liquid B comprising sodium chloride, polymyxin and broth. The detection method includes the enrichment culture of the sample in enrichment liquid A and enrichment liquid B, the culture of the two parts of enrichment cultured liquid in the color developing culture medium, and judging whether to exist Vibrio parahaemolyticus according to whether to have smooth raised purple colony of 2-3 mm diameter. The present invention has low cost, high detection sensitivity, short detection period and other advantages.

The invention provides a flotation activating agent of marmatite and blende, which is a coordination compound of copper and ammonia and is characterized in that the molecular formula of the coordination compound is [Cu(NH3)x]2+, wherein X=1-8. The activating agent of the invention solves the problem of selected activation and inhibition of marmatite, overcomes the problems of low activation selection, low zinc concentrate grade, serious metal mutual containing and the like of common activating agent copper sulphate and solves the problems of high-efficiency enrichment and comprehensive recovery of concomitant rare and noble metal. The activating agent is activated under the condition that pH value is as low as 7-11, provides necessary guarantee for reducing lime dosage in production, reasonably and effectively recovers other sulfide minerals and comprehensively recovers rare metal, and has the advantages of high activation efficiency, low production cost and the like. The invention also applies a preparation method for the flotation activating agent.

The invention discloses a stem-loop structured combined probe and application thereof. The probe is constituted by two DNA sequences of stem-loop structures; from 5' terminals to 3' terminals, probe I and probe II sequentially include stem-loop zones and detection object recognition zones, and are applicable to telomerase activity, RNA and DNA detection and telomerase inhibitor screening; when a detection object is telomerase, the detection object recognition zone of the probe I is a telomerase substrate sequence, and the detection object recognition zone of the probe II is a sequence which is complementary with 8-40 bases in a telomerase extension sequence; and when the detection object is RNA or DNA, the detection object recognition zone of the probe I is a sequence which is complementary with 8-40 bases, close to the 3' terminal, of to-be-detected RAN or DNA, and the detection object recognition zone of the probe II is a sequence which is equal to 8-40 bases, close to the 5' terminal, of the to-be-detected RAN or DNA. The combined probe disclosed by the invention is unnecessary to make use of fluorescence labeling and radioactive element labeling, and the combined probe, with the specific stem-loop structure, provides a specific amplification template for a nucleic acid amplification reaction, so that rapid signal amplification under constant temperature is achieved; and the combined probe is high in sensitivity and amplification efficiency.

The invention relates to an online measurement device of gas partial pressure and an online measurement method thereof. The online measurement device comprises a to-be-measured gas source chamber, a calibration gas source chamber, a pressure reduction chamber, a constant pressure chamber, a vacuum gauge and a mass spectrometry module, wherein a high pressure to-be-measured gas sample injection channel and a medium pressure to-be-measured gas sample injection channel are arranged between a first intake valve and the pressure reduction chamber, a low-pressure to-be-measured gas sample injectionchannel is arranged between the first intake valve and the constant pressure chamber, a calibration gas sample injection channel is arranged between a sixth intake valve and the pressure reduction chamber, a gas circulation channel is arranged between the pressure reduction chamber and the constant pressure chamber, the vacuum gauge is used for measuring vacuum degree of the four chambers above, and the mass spectrometry module is used for online measurement for gas of the constant pressure chamber. The measurement method comprises steps of determining standard sample gas, performing cleanliness detection, acquiring mass spectrometer sensitivity, performing vacuum pumping to remove residual gas and performing online measurement of gas partial pressure. The online measurement device and theonline measurement method of the invention mainly aim at coarse and low vacuum gas analysis, select an optimal sample injection channel according to pressure of the to-be-measured gas and are more accurate in partial pressure measurement.

The invention discloses an efficient adsorbent for separating CO and a preparation method of the efficient adsorbent for separating CO. The preparation method comprises the following steps: weighing a predetermined amount of silica sol, adding a water source for dilution, then dropwise adding an aluminum source solution, a sodium source solution and a copper source solution into the diluted silica sol sequentially, and stirring uniformly to obtain a liquid mixture; aging the liquid mixture for 6 to 10 hours at the room temperature, then adding the liquid mixture to a high-pressure reactor, continuously stirring at the temperature of 95 to 110 DEG C, taking out the mixture after carrying out crystallization for 7 to 12 hours, and washing and filtering the mixture to obtain a solid; performing vacuum drying for the solid at the temperature of 100 to 120 DEG C, and then calcining the solid for 4 to 6 hours under the atmosphere of nitrogen at the temperature of 400 to 500 DEG C to obtain the high-efficient adsorbent for separating CO. The efficient adsorbent for separating CO is prepared with the method and is high in CO selectivity and CO yield. Furthermore, a template agent is not required to be added in the adsorbent, and the high-efficiency adsorbent has a simple preparation process, so that the preparation cost of the adsorbent is effectively lowered.

The invention provides a method for restraining infiltration and metastasis of breast cancer cells by using a target promoting tumour progression factor CCL 18, which is characterized by restraining the action of the CCL18 from tumour related macrophage in a target mode, and specifically, a neutralization antibody of a CCL8 or the siRNA of silent CCL18 mRNA is utilized to restrain the action of the CCL 18. The invention also provides a medicament for restraining the infiltration and metastasis of breast cancer cells, which contains components restraining the action of the CCL 18, comprising the neutralization antibody of the target CCL 18 or the siRNA of the CCL18 mRNA. The invention ensures that the treatment of CCL 18 secreted by a target TAM has general application value and overcomes the selectivity of Drug therapy to cases of breast cancer. The invention provides the method taking the CCL 18 as a target spot, makes up the defects of operation, radiotherapy, chemotherapy and endocrine therapy, and enlarges the range of target therapy.

The invention discloses a preparation method of a magnetic molecularly imprinted composite material of chiral rodenticide bromadiolone. The preparation method comprises the following steps of: adding magnetic nanometer ferroferric oxide particle modified via oleic acid to a dispersing agent; adding polymerizing monomer, functional monomer and cross-linking agent; ultrasonically dispersing; adding an initiator; heating; agitating to react to obtain single dispersive polymer composite microsphere rich in epoxy groups; washing until pH (Potential Of Hydrogen) reaches 6 to 8; then drying; adding composite reacting liquid of bromadiolone and an amino functional agent; heating; agitating to react; magnetically separate; washing until the pH reaches 6 to 8; adding organic solvent; ultrasonically eluting to remove template molecule bromadiolone until no bromadiolone an be detected in the eluant through superfast efficient liquid chromatography-tandem mass spectrum; and then drying to obtain a target product. The preparation method disclosed by the invention has the characteristics of being simple in preparation technology, controllable in magnet content, and controllable in ratio of functional group and the like; a product is applicable to enriching, purifying, analyzing and detecting of bromadiolone residual in a biological sample; and the preparation method has a wide application prospect.

The invention relates to a chiral allyl ester compound and a preparation method thereof. The structural formula of the chiral allyl ester compound is represented in the description. The preparation method comprises the following steps: adding raw materials (carboxylate and allyl halide) into an organic solvent, then adding an iridium catalyst, which is prepared by reacting an iridium complex with a ligand, adding additives, controlling the reaction temperature in a range of 0 to 120 DEG C, carrying out reactions for 1 to 36 hours, and separating the reaction products so as to obtain the chiral allyl ester compound. In the prior art, when active allyl halide is taken as the substrate, the reaction yield is low and the enantioselectivity is bad, and the provided preparation method overcomes the problems mentioned above. Moreover the preparation method has the characteristics of high reaction yield, good region-selectivity, and high enantioselectivity, and thus is widely used in the organic synthesis methodology and natural product synthesis.

The invention discloses a bi-functional catalyst for directly preparing dimethyl ether by carbon dioxide, which is composed of a methanol synthesis active component and a methanol dehydration active component, and the core is to take a composite oxide Cu-Zn-Ti-Zr as the methanol synthesis active component, wherein, the content of CuO is between 10 and 90 percent, 30 to 70 percent preferred; the content of ZnO is 5 to 50 percent, 10 to 40 percent preferred; the molar ratio of Ti / Zr is 0.2 to 6, 0.4 to 4 preferred, the methanol dehydration active component is one or more than one mixture in molecular sieves of HZSM-5, HY, HBeta and HMCM-22, and the methanol synthesis active component and the methanol dehydration active component are mixed through a mechanical mixing method, an impregnation method, a coprecipitation method or a precipitation-deposition method, so as to obtain the catalyst. The prepared bi-functional catalyst has the advantages of high conversion of carbon dioxide and good dimethyl ether selectivity.

The invention relates to an anionic acrylic emulsion containing a cationic monomer and a preparation method of the emulsion. Based on the dry weight of the emulsion, the anionic acrylic emulsion is prepared from a monomer comprising the following components: 80-99 wt% of an acrylate monomer, 0.1-10 wt% of functional monomer acid, 0.1-10 wt% of a cationic monomer and 0.1-5 wt% of an emulsifier. Thepreparation method adopts a step-by-step emulsion polymerization method and includes, firstly, polymerizing a pre-emulsion containing the functional monomer acid; then neutralizing with a neutralizing agent; and then polymerizing the pre-emulsion containing the cationic monomer. The preparation method can be carried out on normal production equipment of the anionic acrylic emulsion without additional equipment. Due to the introduction of the cationic monomer containing amino groups in the anionic acrylic emulsion, a water-based wood sealing primer prepared by the anionic acrylic emulsion hasexcellent tannic acid sealing performance, and overcomes the limitation of raw material selection and construction inconvenience in preparing the primer by the cationic acrylic emulsion.

The invention provides a novel codebook design method based on an ant colony clustering and genetic algorithm. The method includes the following steps: step one, training data are distributed in two-dimensional spaces of different dimensions randomly by using ants of different numbers, and an LF algorithm is adopted to perform generation of initial clustering; step two, clustering correction performed by the initial clustering according to the dimension of a codebook guarantees that the clustering number is the same as initial setup codebook dimensions; step three, under the premise that initial population is obtained successfully, individual selection, intersection and mutation operation are performed according to the basic procedure of a genetic algorithm until iteration is stopped and an optimal individual meeting requirements is obtained. The novel codebook design method based on the ant colony clustering and genetic algorithm overcomes the defect that correlation of initial selection and final design results is strong in an LBG algorithm, meanwhile, prevents similar LBG algorithm from getting into the inferior position of local optimum, and is suitable for the fields of large quantity processing, voice communication, mode recognition, internet protocol (IP) telephony and the like.

The invention discloses a method for depositing a high k gate medium on a graphene material and application, and belongs to the technical field of integrated circuits. The method includes the steps of firstly selecting the graphene material which is smooth in surface and free of defects or less in defects to serve as a substrate sample used for depositing the high k medium; placing the substrate sample in a vacuum cavity of a scanning electron microscope, conducting vacuumizing to the range from 5E-4 to 1E-7, and scanning the surface of the substrate sample through a low-energy focusing electron beam for 30 s to 5 min, wherein the acceleration voltage of the low-energy electron beam ranges from 1 kV to 15 kV; depositing a thin amorphous carbon film on the surface of the substrate sample in the scanning process, wherein the thickness of the thin amorphous carbon film ranges from 0.3 nm to 3 nm; placing the substrate sample processed through the electron beam into an ALD device, and conducting high k medium material deposition. According to the method and the application, medium deposition can still be conducted on the surface of the material without hanging keys through the ALD device, a continuous, uniform and compact high-quality material is obtained, and the application range of the ALD device is widened.

The invention relates to a copper-carried catalyst used for catalyzing hydrogen peroxide or oxidizing benzene to phenol, the preparation and the application thereof. Phenol is an important chemical raw material and also a precursor for preparing Bisphenol A, carbonic ester, phenolic resin, polycaprolactam, detergents, fungicides, herbicides, dyes, adhesives, antioxidants and a plurality of other compounds. Industrially, the demand of the phenol is great, and the world demand exceeds 6.6 multiplied by 10<7> tons per year and increases at the speed of 7 percent to 10 percent annually. A plurality of synthetic routes of the phenol are developed to meet the increasing demand of the phenol. The catalyst takes SBA-16 meso-porous molecular sieve as a carrier and carries transition metal copper, the content of which is 4 percent to 10 percent of the weight of the carrier. The catalyst is applied in the chemical field, namely, oxidizing benzene to phenol directly.

The invention belongs to the technical field of anti-counterfeit package and particularly relates to laser information positioning transfer paper and a preparation method thereof. The laser information positioning transfer paper comprises a paper layer, a digital information layer, a transfer layer, a laser information layer, a plating layer, a glue layer and a paper layer which are successively connected. The plating layer and a carrier are not separated due to a good bonding property, the laser information positioning transfer paper is suitable for packages of various models due to folding resistance of stiffness, different using demands are met due to a large-span base paper range, selectivity on printing ink by a conventional aluminum foil and PET film compound paper are avoided due togood printing ink absorption, the product has wide marketability as a result of plating layers of different colors and lusters and materials, the paper has a brand visual effect due to personal information, and the paper which meets the environmental protection property of trend of the times has a huge popularizing potential.

The invention relates to a method for dating the isotope of limestone Re-Os, and belongs to the technical field of isotope geochronology. The problems that the sampling method is unscientific, the dating samples are blindly selected, the success rate of dating is low, the sample digestion is incomplete and takes a long time, and the impurity interference caused by a dissolution scheme causes the poor accuracy and precision of the limestone Re-Os isotope age results. The method comprises the following steps: collecting a limestone sample and crushing the sample; selecting a limestone dating sample deposited in a reducing environment; pre-digesting the limestone dating sample, and dissolving a pre-digesting solution of the limestone dating sample with a mixed solution of hydrochloric acid and hydrogen peroxide; separating and purifying a dissolution solution Re-Os of the limestone dating sample; performing the Re-Os isotope thermal ionization mass spectrometry; processing the Re-Os isotope data to obtain the final limestone Re-Os isotopic age. The analysis method provided by the invention has the advantages of improving the success rate, accuracy, precision and the operation efficiency of the experimental process of the limestone Re-Os isotope dating.

The invention discloses a method for selecting benchmarking photovoltaic components of a photovoltaic power station on basis of principal component analysis. The method includes that historical output curves of each photovoltaic module of the photovoltaic power station are acquired; a photovoltaic module output matrix Xmxn is established based on the historical output curves of each photovoltaic module of the photovoltaic power station; the m refers to the number of the photovoltaic modules of the photovoltaic power station, the n refers to the number of power samples of each photovoltaic module, and Xij refers to the ith photovoltaic module and actual output of the jth time point; the photovoltaic module output matrix is subjected to principal component analysis after being preprocessed; principal components having category differentiation are taken as a basis for selecting the benchmarking photovoltaic modules. The method for selecting benchmarking photovoltaic components of the photovoltaic power station on basis of the principal component analysis has the advantages that the defects of low selection efficiency and poor selection effect and the like in the prior art are overcome, and high selection efficiency and good selection effect are realized and the like.

The present invention belongs to the field of pharmaceutical preparations, and relates to a polypeptide drug delivery system, particularly to a micelle preparation entrapped with binding peptide polymer with specific anti-cancer activity. The drug delivery system consists of a targeted functional material, an amphiphilic block copolymer and a binding peptide. By entrapping a binding peptide capable of restoring the activity of a tumor suppressor protein p53, the binding peptide is delivered into cancer cells to exert the activity of inhibiting tumor cell growth and increase targeted anti-cancer effect; and the binding peptide has better anti-cancer effect by combination with temozolomide. By in vivo and in vitro active valuation, the drug delivery system is proved to be able to successfully deliver binding peptides to the target site and send binding peptides into the target cells, and has clear therapeutic effect.

The invention belongs to the technical field of protective films and adhesive tapes, and specifically discloses an easily-prepared thermal visbreaking adhesive tape and a preparation method thereof. The thermal visbreaking adhesive tape comprises a plastic base material, which is coated with a thermal visbreaking functional layer, wherein a thermal visbreaking adhesive is coated on the plastic base material and is cured to form the thermal visbreaking functional layer, the thermal visbreaking functional layer is coated with an adhesion layer, and the adhesion layer is coated with a release film. According to the invention, the plastic base material is coated with the thermal visbreaking functional layer, the thermal visbreaking functional layer is coated with the adhesion layer, and finally the adhesion layer is compounded with the release film; and the working principle is that when the external temperature reaches above the working temperature of the thermal visbreaking functional layer, the microspheres in the thermal visbreaking adhesive tape expand by several times or even dozens of times to cause the foaming of the adhesion layer so as to make the surface become rough to reduce the viscosity, so that the thermal visbreaking functional layer and the adhesion layer are processed in two procedures so as to avoid the selectivity of the microspheres to the adhesive in the traditional thermal visbreaking adhesive tape preparation process.