236results about How to "Not easy to release" patented technology

The present invention relates to a preparation technique and an application of unsaturated fatty acid microcapsules. The preparation technique of the unsaturated fatty acid microcapsules is characterized in that the present invention includes the following steps: 1) the selection of the raw materials: the inner layer coating materials and the outer layer wall materials are selected for standby according to that the weight ratio of the inner layer coating materials and the outer layer wall materials is 0.7 to 1.5: 3 to 5; the inner layer coating materials are unsaturated fatty acid; the outer layer wall materials are the mixture of any two or more of the natural rubbers, carbohydrates and soluble proteins; 2) the outer layer wall materials are mixed evenly, the weight ratio of the outer layer wall materials and the water is 3 to 4: 6 to 7, the evenly mixed outer layer wall materials are added after the water temperature is increased to 50 DEG C, so as to get the pre-emulsion; 3) the inner layer coating materials are added into the pre-emulsion and is homogenized at the high pressure of 30 to 35MPa, so as to get the emulsion; 4) the emulsion is treated by the spray drying, the materials after the spray drying is cooled by a fluidized bed, the cooling temperature is 30 to 50 DEG C, then the materials pass through a 20 to 60 mesh vibrating screen, so as to get the unsaturated fatty acid microcapsules. The present invention is characterized by water repellency.

The invention relates to a method for preparing high-purity rice protein. The method comprises the following steps: sizing mixing and grinding, degreasing, enzymolysis reaction, separating washing and blanching and sterilization. The invention also relates to the high-purity rice protein acquired by using the method, wherein the rice protein contains following components by weight percent: more than 80% of protein, less than 3% of fat, and less than 3% of ash content. The protein extraction ratio is more than 80% and the additional value of rice residue is greatly increased.

A tablet cassette for a medicine packing machine is disclosed. The tablet cassette for a medicine packing machine includes a cassette for accommodating tablets and having a passage formed at one side of a lower end thereof, a cassette support with which the cassette is detachably coupled on the upper surface of the cassette support and which has an inclined passage communicated with the passage in one side thereof, and a discharge driver provided in the cassette and the cassette support. The discharge driver includes a conic rotating body provided in the cassette and having divisional protrusions on the outer circumference thereof, and a driving motor provided in the cassette support to rotate the rotating body in a forward direction and to rotate the rotating body in a reverse direction when tablets are lodged such that overload is generated.

The invention relates to a preparation technique of a medicine alogliptin benzoate for treating Type 2 diabetes. The technique comprises the following steps: reacting the raw material 6-chloro-3-methyluracil with 2-cyanobenzyl bromide to prepare 2-(6-chloro-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidyl-ylmethyl)-benzonitrile, and carrying out substitution reaction with (R)-3-Boc-aminopiperidine; after the reaction finishes, removing Boc to obtain alogliptin; and finally, salifying with benzoic acid to obtain the alogliptin benzoate. The invention is characterized in that in the substitution reaction, the acid binding agent potassium carbonate is added; and after the reaction finishes, filtration is carried out, and p-toluenesulfonic acid is added into the filtrate to remove the Boc. The preparation technique provided by the invention has the advantages of simple procedure, higher product yield and higher product purity.

The embodiment of the invention discloses a pixel circuit and a display device. The pixel circuit comprises a data voltage write-in module, a driving module, a storage module, a light emitting module and a leakage current suppression module. The data voltage write-in module is used for writing data voltage into the control end of the driving module. The storage module is used for storing data voltage of the control end of the driving module. The driving module is used for driving the light-emitting module to emit light according to the data voltage of the control end of the driving module. The leakage current suppression module is electrically connected with the control end of the driving module and is used for maintaining the potential of the control end of the driving module. The potential of the control end of the driving module is not easy to release in the light emitting stage, so that the potential of the control end of the driving module can be well maintained, and the display effect is improved. Moreover, the driving frequency of the pixel circuit can be reduced, and the power consumption of the whole display device comprising the pixel circuit is reduced. And the area of the storage module can be reduced, so that the pixel density can be improved.

The invention belongs to the technical field of in-situ repair of heavy metal contaminated soil. Municipal sludge is used for preparing sludge-based charcoal through thermophilic thermolysis. The charcoal can be used as a repairing agent for the heavy metal contaminated soil. The sludge charcoal repairing agent comprises thickened sludge and palygorskite. A final black product namely the sludge-based charcoal is produced through the steps of performing biological and physical anhydration on sludge, then mixing the sludge after the biological and physical anhydration with the palygorskite, performing feeding into an atmosphere furnace, and then performing thermophilic thermolysis. The sludge charcoal is produced from the following components of 5-10% of the palygorskite and the balance of thethickened sludge. According to the sludge charcoal disclosed by the invention, the municipal sludge is subjected to decrement and harmless treatment, so that the municipal sludge can enter cycle of material and energy in natural environment again, and the difficult problem of treating and disposing the sludge is solved. The sludge charcoal is added to the heavy metal contaminated soil, so that heavy metal contaminated substances can be effectively solidified, the purposes of being durable and stable in repairing effect and being free from secondary pollution are realized, and the sludge charcoal is an ideal soil heavy metal contamination repairing agent with low cost.

An adhesion device is made up of three parts: an anchor portion; a peeler layer; and a “biomimetic microstructure adhesive” (BMA) portion. The anchor portion has one side affixed to a part of an object to be releasably adhered to a surface. The peeler layer has an inwardly facing side thereof affixed to the other side of the anchor portion. The BMA portion is affixed to an outward side of the peeler layer with its setae facing outwardly towards the surface to be adhered to. The anchor portion is affixed to the peeler layer at a position offset from the position at which the BMA portion is affixed, so that the object may be releasably detached from adhesion with the surface.

A sun shade for a hard hat includes a piece of flexible material removably and adjustably attached to a hard hat that is stretched to a substantially consistent shape by a piece of springing material. The flexible material may be attached to the hard hat using an elastic band, drawstring, or similar means for attaching. When not in use, the springing material may be removed from the flexible material and stored as a straight piece of material or rolled and stored as a coil. Additionally, the flexible material, such as fabric or soft plastic, may be folded and stored. The flexible material may also include a flap that drapes over the sides and back of the user's neck to provide enhanced protection from direct radiant energy.

The invention provides camptothecin-adriamycin prodrug. A structural formula of the prodrug is shown as a formula (I), wherein R1 is camptothecin or derivative group thereof, R2 is one of -CH2- or -O-, R3 is one of -CH2- or -O-, X is one of S or -CH2-, and n1 and n2 are numbers of repeated units, and are integers from 0 to 10. The prodrug can be easily wrapped by amphiphilic polymer to form nanoparticles. The nanoparticles are high in drug carrying efficiency and drug carrying capacity and capable of quickly releasing unmodified camptothecin and adriamycin in the presence of glutathione, and the nanoparticles can be effectively taken in by tumor cells to kill the same. The invention further provides a preparation method of the prodrug, a preparation of the prodrug and application of the prodrug in preparing cancer treating drug.

An igniter can include a safety mechanism which is easily operated by an adult but is difficult for a child to release. In particular, an igniter can include: a nozzle section which emits a flame; a fuel introduction section; an ignition section which ignites the introduced fuel, wherein the ignition section is configured in such a manner that the fuel is ignited by movement of an ignition operating section to an ignition position; a movement restricting section having restricting sections which restrict the movement of the ignition operating section; and a permitting section which permits movement. When moving the movement restricting section, either the restricting sections or the permitting section can be disposed so as to correspond to the direction of movement of the ignition operating section.

The invention discloses a vivianite crystal front dephosphorization method based on the AAO / AO process, and belongs to the technical field of sewage processing. The method includes the steps of makingcrude sewage and sludge flowing back from a secondary depositing pool synchronously enter an anaerobic pool of the AAO / AO process for phosphorus release, putting Fe3+ / Fe2+ salt in the anaerobic pool,reducing Fe3+ into Fe2+ under the effect of dissimilar metal reducing bacteria, making Fe2+ react with phosphorus in the anaerobic pool to generate vivianite crystals, arranging an anaerobic standingarea communicated with the anaerobic pool at the rear end of the anaerobic pool, making sludge-water mixed liquid containing a large amount of vivianite enter the anaerobic standing area for depositing and separating, making the sludge containing a large amount of vivianite at the bottom of the anaerobic standing area discharged out of a system through a sludge discharge pipe, separating out supernate of the vivianite sludge, and making the supernate enter the subsequent stage of the AAO / AO process for processing. The method is simple and easy to implement, basically no additional processingunits need to be added, cost is low, and the dephosphorization effect is good.

A padlock having a horizontal shackle is disclosed. The padlock may include a base comprising a latching mechanism, a first shackle aperture, and a second shackle aperture. The padlock may also include a shackle. The shackle may comprise a first post extending from within the first shackle aperture, a second post extending from within the second shackle aperture, and a horizontal cross member extending in a line from the first post to the second post.

The invention pertains to the technical field of treatment of waste water, and particularly relates to a method of hydrolysis-catalytic iron-aerobic coupling for treating poisonous and harmful hard-degradation waste water, which comprises the following steps: waste water after primary treatment directly enters an up flow type hydrolysis system 1 and stays for 4.0-10.0 hours; the effluent enters an electrolytic cell in the catalytic iron; the mass ratio of iron scraps and copper scraps in the electrolytic cell of the catalytic iron is 1:1 to 20:1, the bulk specific weight thereof is 0.1 to 0.3, the contact time thereof in a filling area is 0.5 to 2.0 hours, and the reflux ratio of the effluent refluxing to the up flow type hydrolysis system is 20 to 100 percent; the effluent enters an aerobic biological treatment system and stays for 6.0 to 12.0 hours; then the effluent enters a solid-liquid separation system with a reflux ratio of sludge being 10 to 50 percent; and the effluent of the solid-liquid separation system refluxes to the electrolytic cell of the catalytic iron with the reflux ratio being 20 to 200 percent. Under the premise of fully playing the function of different treatment units and maintaining the treatment effect and respective advantages, the treatment method of waste water realizes the coupling synergetic action of the three units, strengthens the impact of the system to water quality and water quantity load, reduces a plurality of steps of pretreatment, effectively improves the removal rate of ammonia nitrogen, and can be flexibly adjusted.

The invention relates to a complex processing method for prolonging the service lift of chain grate key parts, belonging to mechanical manufacturing and material processing and application technical field, which comprises: firstly, surface nondestructive testing is carried out on the key parts of the chain grate of process; molten salt complex processing are carried out in parts of the surface according to the surface drawbacks tested by surface nondestructive testing; before the laser shocks, the workpiece surface is coated with black coating layer and use water as protective layer, and the laser shock processes the area which is easy to fatigue and fracture and has concentrated stress. The molten iron pretreatment spray-feeding device before iron-making blast furnace has the advantages of simple shortcut, high efficiency, low maintenance cost, short processing time (30 minutes to 5 hours), and the continuous operation can be realized, thus, high efficiency of production is ensured.

The invention relates to an imidazole epoxy curing agent micro capsule and a preparation method thereof, belonging to the technical field of latent epoxy curing agents. According to the curing agent micro capsule, polysulfone plastic is adopted as a wall raw material, an imidazole epoxy curing agent is adopted as a capsule core, and an emulsion-solvent evaporation method is adopted to prepare the polysulfone coated imidazole epoxy curing agent micro capsule. The preparation method of the micro capsule provided by the invention is simple in process and low in cost; the imidazole epoxy curing agent micro capsule is solid powder and has the characteristics of high coating rate and stability at normal temperature; as the imidazole curing agent is embedded into a container of a polysulfone polymer, the imidazole curing agent is not easy to release at normal temperature, is convenient to store and transport, can achieve the purpose of rapid curing by only being heated to be an appointed temperature when being used, and can be widely applied to the fields such as latent prepreg, self-repairing composite materials and semiconductor device packaging materials.

The invention discloses a preparation method of an environment-friendly asphalt pavement anti-rut agent and an application thereof. The method comprises the following steps of: mixing and stirring 45-80 percent of polyethylene and 15-30 percent of petroleum resin derived from 'plastic waste', 5-15 percent of polymethyl methacrylate, 5-15 percent of an asphalt material and 0-10 percent of an inorganic mineral filling material at a high speed; and extruding at a high temperature to prepare the environment-friendly asphalt pavement anti-rut agent. Due to the adoption of the environment-friendly asphalt pavement anti-rut agent, the performance of an asphalt pavement is enhanced, the service life of the pavement is prolonged, 'white waste' is recycled, and environmental pollution is lowered. Polyethylene serving as a major component is either or both of industrial production low-density polyethylene and industrial recycled waste polyethylene; the industrial recovered waste polyethylene is recovered polyethylene or regenerated low-pressure polyethylene or regenerated PE (Polyethylene); the molecular weight of the petroleum resin is 300-3,000; the molecular weight of the polymethyl methacrylate is 80,000-120,000; the asphalt material is one or more of natural asphalt, coal tar asphalt and petroleum asphalt; and the inorganic mineral filling material is one or over two of calcium carbonate of 500-800 meshes, talc powder, quartz sand, glass hollow microspheres and kaolin.

The invention relates to a polymer composition loaded with a sirolimus compound or its derivative. The composition can have diversified forms. A necessary link includes preparing the sirolimus compound or its derivative and a polymer carrier into a micelle. Then according to needs, the micelle can be further prepared into a freeze-dried composition by a freeze-drying technology, or the micelle and other polymer and carrier can be prepared into a solid or semi-solid preparation. The polymer composition can be used for treating tumors, reducing rejection reactions after organ and tissue transplantation, promoting cell regeneration and repair, preventing excessive scar tissue growth after injury and preventing vascular restenosis and blood coagulation embolism, treating or inhibiting autoimmune diseases, and treating or inhibiting inflammation, etc.

The invention discloses an internal sinking expansion self-floating type sewage oil stain adsorption ball, and belongs to the field of sewage treatment. The internal sinking expansion self-floating type sewage oil stain adsorption ball comprises a concave surface suction ball , the lower end of the concave surface suction ball is fixedly connected with a plurality of oil suction fluff; a counterweight floating ball is arranged, the overall gravity of the adsorption ball can be effectively increased, when the adsorption ball is added into sewage, the adsorption ball can sink into sewage, therefore, part of oil drops which are not layered on the sewage surface can be directly adsorbed and then the time for adsorbing oil stains after standing to achieve water-oil layering in the prior art iseffectively saved, the adsorption efficiency is obviously accelerated, the concave surface adsorption ball expands and is released along with gradual increase of the oil stain adsorption amount, the overall gravity of the adsorption ball is reduced, meanwhile, the balance weight floating ball floats upwards under the action of sewage buoyancy to drive the concave surface adsorption ball to ascendand float to the water surface, then it is effectively guaranteed that a worker recycles and replaces the oil stain adsorption ball, and the oil stain adsorption efficiency is effectively guaranteed.

The invention discloses a nano-modified polyurethane packaging material and a preparation method thereof, and relates to a composite material, a structural material and a preparation method of the composite material. The nano-modified polyurethane packaging material is prepared by the following steps: preparing a white material composition from modified graphene, polyether polyol, polyester polyol, a foaming stabilizer, glycerinum, water, cyclopentane, triethylene diamine (33% water solution) and stannous octoate; mixing with polyisocyanates; and heating and foaming, so as to prepare the nano-modified polyurethane packaging material. The nano-modified polyurethane packaging material is convenient to produce, manufacture and transport, low in production cost, good in buffer shock resistance, high in support strength, good in texture, light in weight, good in waterproofness, free of damage of worms, not easy to deform, free of a poisonous gas styrene, friendly to environment, and antistatic, and is capable of resisting interferences such as electromagnetic valves and radio frequency; and the method is suitable for fabrication of the packaging materials of instruments, equipment, electronic products, electric tools and the like.

The invention provides a heterodimer multifunctional prodrug based on camptothecin. The heterodimer multifunctional prodrug is loaded with the camptothecin and 2-(1-hexyloxy ethyl)-2-devinyl-pyropheophorbide-a (HPPH), the prodrug is a camptothecin-HPPH prodrug formed by the camptothecin and the HPPH through a connecting group, and the structural formula of the prodrug is as shown in formula (I), wherein R is the connecting group and is one of -SS-, -CH2CH2- or -S(CH3)C(CH3)S-; R1 is the camptothecin group. The prodrug has the advantages that the prodrug can be easily wrapped by amphiphilic polymer to form nano particles, and the formed nano particles are high in drug loading efficiency and drug loading capacity and can fast release the unmodified camptothecin and HPPH in the presence of glutathione; meanwhile, the nano particles can be effectively absorbed by tumor cells to kill the tumor cells. The invention further provides a preparation method and preparation of the prodrug and application of the prodrug in the preparation of drugs for treating cancer.

A composite strip of compacted powders, which has a three layers structure, is continuously obtained by means of a rolling machine for powder compacting. The composite strip is sintered at a temperature of 460° C. to 550° C. to form a sintered composite strip. The sintered composite strip is continuously bonded by rolling to a steel strip. The bonded composite strip is optionally subjected to a heat treatment of heating at a temperature of 250° C. to 400° C. followed by heating to a temperature of 400° C. to 510° C., holding the strip under the temperature for not less than 30 seconds, and rapidly cooling down to 300° C. at a cooling rate of not lower than 50° C. / minute, whereby obtaining a multi-layered composite material consisting of the steel strip, a sintered bonding layer, a sintered sliding layer and a sintered sacrificial layer. At least one selected from a low-melting-point element group of Sn, In and Pb is added to raw powders to be formed to surface layers of the sintered composite strip, which are the sintered bonding layer and the sintered sacrificial layer, in an amount of 0.4 to 5 mass % and 0.4 to 25 mass %, respectively.

The invention relates to a method for producing rotavirus vaccines in large scale by utilizing a bioreactor, and in particular relates to a method for culturing rotavirus inactivated vaccines in large scale by utilizing a 75L bioreactor. The method comprises the following steps: (1) carrying out reviving and passage on Vero cells; (2) collecting the cells and inoculating the cells into the bioreactor; (3) culturing the cells in the bioreactor; (4) changing the liquid and washing the cells; (5) activating and infecting rotaviruses; and (6) carrying out maintenance culture and harvesting on the rotaviruses. The method aims at overcoming the defect that in the large-scale production, the rotaviruses can not release cells easily, so that the obtained viruses are low in toxicity titer, and the inactivated rotavirus vaccines with high titer and high yield are obtained; the method also aims at overcoming the defect that in the large-scale production, the adsorption force and infection force of the rotaviruses are poor, and thus the yield and quality of the rotaviruses are greatly improved.

The invention discloses an arsenic-trioxide-carrying pH-responsive mesoporous silica nanoparticle and a preparation method thereof. The preparation method of the arsenic-trioxide-carrying pH-responsive mesoporous silica nanoparticle mainly comprises the following steps: preparing amino modified mesoporous silica by adopting a coprecipitation method, and loading conjugate acid and base ATO and PAA through electrostatic adsorption for preparing PAA-ATO-MSNs. The prepared PAA-ATO-MSNs are circular or quasi-circular in appearance under a transmission electron microscope, average particle size is (158.6+ / -1.32)nm, Zeta potential is (-28.40+ / -0.34)mV, and encapsulation efficiency and drug loading rate are (40.95+ / -3.21)% and (11.42+ / -1.75)% respectively; in vitro drug release is pH-responsive, and accumulated release amount is increased along with reduction of pH value; pharmacokinetic study shows that compared with ATO-Sol and ATO-MSNs, t1 / 2beta of PAA-ATO-MSNs is obviously prolonged and AUC is obviously increased (P is less than 0.01); and PAA-ATO-MSNs in vitro drug release has obvious pH responsiveness and sustained release property, in vivo pharmacokinetic behaviours of a rat can be obviously improved, and the arsenic-trioxide-carrying pH-responsive mesoporous silica nanoparticle carrier can serve as an ATO tumour-targeted drug delivery system and has a good application prospect.

The invention relates to a reparative conductive adhesive. The reparative conductive adhesive consists of the following components in parts by weight: 100 parts of epoxy resin I, 250-900 parts of sheet silver powder, 10-50 parts of a curing agent I, 0-40 parts of an epoxy diluent I, 3-20 parts of a coupling agent and 8-60 parts of composite mesoporous particles, wherein a curing temperature of an epoxy resin composition I consisting of the curing agent I, the epoxy resin I and the epoxy diluent I is 60 DEG C-80 DEG C; the composite mesoporous particles adopt mesoporous silicon dioxide loaded with nano sliver as a carrier, a wall capsule material layer is arranged on the outer surface of the carrier, an epoxy resin composition II is contained in a mesopore, the curing temperature of the epoxy resin composition II is not lower than 150 DEG C, an epoxy diluent II in the epoxy resin composition II is not dissolved or difficultly dissolved in water with a boiling point not lower than 150 DEG C. The invention further relates to a preparation method of the reparative conductive adhesive. The conductive adhesive is high in repair efficiency and can avoid generating stress concentration at repaired cracks.

The invention discloses a molecule-refining oxygen-dissolution aeration device including a support, a housing fixedly arranged on the support, a center shaft arranged in the housing, a variable-screw-pitch helical blade assembly, and a gas-liquid mixing input pipe and a dissolved gas refined fluid output pipe which are connected at both ends of the center shaft at both ends of the housing respectively; the variable-screw-pitch helical blade assembly is arranged on the center shaft, both ends of the center shaft are each provided with a guide cone. With utilization of the action of mechanical cutting and hydraulic shearing, bubbles are broken and refined, gas is dissolved in a supersaturated manner, is maintained in water and is not easy to release, and at the same time, various suspended solids and macromolecular organic compounds dissolved in the water flowing through the device are cut and refined. The molecule-refining oxygen-dissolution aeration device can be directly used in aerobic biological treatment for sludge and wastewater treatment and polluted water body purification, and also can be used for aquaculture oxygenation, preparation of oxygen-enriched water, beverage aerating and other liquid gas-dissolution fields, and the refining mixing fields in a chemical production process.