81results about How to "Not easy to catch" patented technology

The invention discloses an amphiphilic polypeptide DGRGGGAAAA and a preparation method thereof, and a novel anticancer drug delivery system and a preparation method thereof; the preparation method of the amphiphilic polypeptide DGRGGGAAAA comprises: 1) using DMF (dimethyl formamide) as a solvent, DCM (dichloromethane) as an expanding agent and DIC (diisopropyl carbodiimide) as a catalyst to synthesize DGRGGGAAAA by a solid-phase synthetic process; 2) mixing the DGRGGGAAAA and doxorubicin (DOX), dissolving the mixture in water, subjecting the system to multiple dialysis, centrifuging the dialyzed system, and removing supernate to obtain the novel anticancer drug delivery system. The novel anticancer drug delivery system has significantly improved efficiency, and has the advantages of high targeting action, small side effect, low toxicity and the like.

The present invention discloses a system used for pet fitness and a control method therefor. The system comprises a training apparatus and a signal transceiver; the training apparatus comprises a base, wherein an upright column, a central processing unit, a first wireless communication module and a first UWB (Ultra Wide Band) positioning sensor are arranged on the base; a rotating mechanism is arranged on the upright column, the rotating mechanism is connected to a cross beam, a guide rail is arranged on the cross beam, a sliding block and a driving mechanism that drives the sliding block to move are arranged on the guide rail, and a spherical food storage apparatus is arranged below the sliding block; a second UWB positioning sensor, a second motorized telescoping pole and a third motorized telescoping pole are arranged on the top of the upright column, the second motorized telescoping pole and the third motorized telescoping pole are arranged transversely, a third UWB positioning sensor is arranged at the front end of the second motorized telescoping pole, and a fourth UWB positioning sensor is arranged at the front end of the third motorized telescoping pole. The system for pet fitness has quite high interestingness and easily attracts a pet, so that the pet can interact with the training apparatus so as to achieve the good fitness effect.

Provided is a preparation method for polymerization-type asymmetric hindered phenol anti-oxidant resins. The preparation method comprises steps: with strong acid resins as catalysts, and benzene or cyclohexane as a solvent, 2-tert-Butyl-p-cresol and dicyclopentadiene are subjected to a polymerization reaction to form phenol-type petroleum resins; the phenol-type petroleum resins and saturated alcohols with one to three carbons are subjected to an alkylation reaction to form polymerization-type asymmetric hindered phenol anti-oxidant resins in presence of phosphoric acid and nickel-containing catalysts; the alkylation reaction products are subjected to reduced pressure distillation to remove the unreacted raw materials and solvent to obtain polymerization-type asymmetric hindered phenol antioxidant resin products. The preparation method has obvious positive effects, the polymerization reaction and the alkylation reaction have high selectivity and conversion rate, and the yield is about 80%. What is more important is that compared to traditional hindered phenol antioxidants, the synthesized polymerization-type asymmetric hindered phenol antioxidant resins are advantaged by high antioxidant activity, high heat stability, extracting resistance, compatibility, non-toxic and environmentally friendly characteristics.

Provided is a preparation method for polymerization-type asymmetric hindered phenol anti-oxidant resins. The preparation method comprises steps: with boron trifluoride complex as a catalyst and benzene or cyclohexane as a solvent, p-methylphenol and dicyclopentadiene are subjected to a polymerization reaction to form phenol-type petroleum resins; after alkali washing and water washing, the polymerization reaction products are subjected to reduced pressure distillation to remove unreacted p-methylphenol in the reaction liquid to obtain refined phenol-type petroleum resins; the phenol-type petroleum resins, saturated alcohols with one to three carbons and isobutanol are subjected to an alkylation reaction to form polymerization-type asymmetric hindered phenol anti-oxidant resins in a solvent in presence of phosphoric acid and nickel-containing catalysts; the alkylation reaction products are subjected to reduced pressure distillation to remove the unreacted raw materials and solvent to obtain polymerization-type asymmetric hindered phenol antioxidant resin products, and the yield is about 90%. The preparation method has obvious positive effects, through asymmetric substituent groups antioxidant effects are raised. Compared to traditional phenol antioxidants, the synthesized polymerization-type asymmetric hindered phenol antioxidant resins are advantaged by high antioxidant activity, high heat stability, extracting resistance, compatibility, non-toxic and environmentally friendly characteristics.

The invention discloses a pet fitness training system and a working method thereof. The system comprises a training device and a signal transceiver. The training device comprises a base. The base is provided with a stand column, a central processing unit, a first wireless communication module, and a first UWB alignment sensor. The stand column is provided with a rotation mechanism. The rotation mechanism is connected with a cross beam. The cross beam is provided with a guide rail. The guide rail is provided with a sliding block and a driving mechanism driving the sliding block to move. A food storage device is arranged under the sliding block. The top of the stand column is provided with a second UWB alignment sensor, a second electric expansion link, and a third electric expansion link. The front end of the second electric expansion link is provided with a third UWB alignment sensor. The front end of the third electric expansion link is provided with a fourth UWB alignment sensor. The system has very good interestingness, and can easily interest pets. Through interaction with the training device, pets can achieve very good fitness effect.

The invention provides a solar cell based on a two-dimensional perovskite single crystal and a production method thereof. The two-dimensional perovskite single crystal is used as a light absorption material of the solar cell, the two-dimensional perovskite single crystal comprises N layers of two-dimensional perovskite single layers, and the N is greater than or equal to 2; the two-dimensional perovskite single layer comprises n layers of common-angle lead iodide octahedrons, n-1 layers of organic ligands A and two layers of organic ligands B, wherein n is greater than or equal to 1, and the two-dimensional perovskite single layers have the same n value; the organic ligands A are embedded into a gap of the common-angle lead iodide octahedrons, the organic ligands B are located on two opposite sides of the common-angle lead iodide octahedrons respectively, a chemical formula of the two-dimensional perovskite single layers is B2An-1PbnI3n+1, and the number of carbon atoms of the organicligands B is larger than that of the organic ligands A; and the solar cell based on the two-dimensional perovskite single crystal has advantages of high environmental stability and high photoelectricconversion efficiency.

The invention discloses an electro precipitator utilizing ionic wind to assist in dust collection and a polar plate. Theelectro precipitator comprises a front electric field and a rear electric field which are formed by symmetrically arranging a plurality of pairs of electro precipitator dust collection polar plates of the same structure, wherein barbed wire discharge electrodes are arranged between the electro precipitator dust collection polar plates of the front electric field, long-groove-shaped frame-shaped plates of symmetrical structures are arranged on the inner sides of the electro precipitator dust collection polar plates at the rear parts of the barbed wire discharge electrodes to form a cavity, and the opening direction of the cavity faces an airflow inlet; round wire discharge electrodes are arranged between the electro precipitator dust collection polar plates of the rear electric field; and the distance between the electro precipitator dust collection polar plates of the front electric field is smaller than that between the electro precipitator dust collection polar plates of the rear electric field. According to the novel polar plates with the cavity, fine particles can be effectively captured by utilizing ionic wind generated by discharging, the dust removal efficiency of the electric dust remover on dust with high and low specific resistances can be improved by utilizing the electrostatic shielding effect of the cavity, the application range of the electro precipitator on dust with different specific resistances is expanded, and therefore, the overall dust collection efficiency is improved.

The invention discloses a placenta microenvironment targeted delivery probe as well as a preparation method and application thereof. A) a shell is a lipid bimolecular membrane which is modified by enzyme substrate polypeptide-PEG and is subjected to targeted disintegration under the action of an enzyme which is in contact with placenta tissue interstitial fluid and is highly expressed, and B) an inner core is a drug carrier which is modified by a marker antibody which is specifically and highly expressed on the surface of placenta trophoblast; and C) loading superparamagnetic ferroferric oxide SPIO nanoparticles, a small molecule drug for regulating and controlling the functions of placental trophoblasts, a therapeutic gene or a combination thereof in the drug carrier. The placenta microenvironment targeted delivery probe disclosed by the invention can effectively avoid non-specific drug absorption of other organs outside the placenta of a maternal body and a fetus, so that delivery and function regulation and control of a trophoblast specific drug in the placenta are realized.