The invention discloses a B-pillar structure of a frameless vehicle door and a vehicle, and the structure comprises a B-pillar body; the B-pillar body comprises a B-pillar inner plate and a B-pillar reinforcing piece, the transverse section of the B-pillar inner plate is in an n shape, an opening faces the B-pillar reinforcing piece, and the B-pillar inner plate and the B-pillar reinforcing piece define a cavity; a thermal forming patch plate is arranged on the side wall, close to the B-pillar reinforcing piece, of the upper portion of the B-pillar inner plate, the side wall, close to the B-pillar inner plate, of the lower portion of the B-pillar reinforcing piece is fixedly connected with a hinge reinforcing piece, and the upper portion of the hinge reinforcing piece and the lower portion of the thermal forming patch plate are partially overlapped in the radial direction. And the lower end of the B column body is riveted and fixed with an aluminum alloy doorsill boundary beam. The side impact performance of the B-pillar structure can be guaranteed, the problems that when a traditional B-pillar structure is applied to a frameless vehicle door, the strength is poor, the invasion amount of a B-pillar is large, and the B-pillar is bent are solved, and the safety performance of the whole vehicle is effectively improved.