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32results about How to "Maintain biocompatibility" patented technology
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Preparation of antibacterial silver/chitosan nano fiber membrane
InactiveCN101297976AImprove mechanical propertiesRemain biodegradableSurgeryFilament/thread formingFiberStaphylococcus aureus
The invention discloses a preparation method of antibacterial silver / chitosan nano fibrous membranes, pertaining to the preparative technologies of nano composite fibrous membranes. The process of the method includes that a chitosan hexanoic acid solution, a silver nitrate aqoeous solution, a sodium borohydride water solution and an ethylene epoxide hexanoic acid solution are prepared and mixed to form compounded latex according to the volume ratios of the chitosan hexanoic acid solution and the silver nitrate aqoeous solution as well as an NaBH4 aqueous solution. The compounded latex and the ethylene epoxide hexanoic acid solution are mixed according to the volume ration to prepare a spinning solution, then the spinning solution is added into an injector in an electrostatic spinning device and electrostatic spinning is carried out to form the fibrous membrane. Crosslinking treatment is carried out to the fibrous membrane to obtain the antibacterial silver / chitosan nano fibrous membrane. The antibacterial silver / chitosan nano fibrous membrane of the invention has the advantages that the preparation process is simple; the prepared membrane material has broad-spectrum bactericidal property and comparatively high fatality rate to Bacillus coli, Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa for 24 hours.
Owner:TIANJIN UNIV
Cathode mixture for use in a biocompatible battery
ActiveUS20160056459A1Maintain structureGuaranteed functionEye implantsFinal product manufactureEngineeringAnode
Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.
Owner:JOHNSON & JOHNSON VISION CARE INC
Detection of nano-scale particles with a self-referenced and self-heterodyned raman micro-laser
InactiveUS20150285728A1Maintain biocompatibilityEasy to useNanotechRadiation pyrometryWhispering galleryParticle size measurement
A system and method for is a micro-laser based nano-scale object detection system and method using frequency shift and / or mode splitting techniques. The system and method can provide highly sensitive detection of nanoparticles with a self-referenced and self-heterodyned whispering-gallery Raman micro-laser. The system and method also provides for nano-particle size measurement.
Owner:WASHINGTON UNIV IN SAINT LOUIS
Lysine-chitosan resin and preparation method thereof
InactiveCN1927892ASimple componentsSimple manufacturing methodCosmetic preparationsOrganic active ingredientsCross-linkPolymer science
The present invention is lysine-chitosan resin and its preparation process, and relates to chitosan modifying technology with lysine. The lysine-chitosan resin consists of chitosan, glutaraldehyde and lysine simply. The preparation process of lysine-chitosan resin includes the first reverse suspending process to prepare chitosan microsphere, the subsequent cross-linking with glutaraldehyde as cross-linking agent to prepare cross-linked chitosan resin and final modification with lysine to prepare the lysine-chitosan resin. The lysine-chitosan resin has homogeneous granularity, rich pores, high acid and alkali resistance and excellent effect of adsorbing acid radical anion, amino acid and protein, is regenerable, and may be used widely in medicine, food, cosmetics, water treatment, chemical and other fields.
Owner:CHONGQING UNIV
Carbon-based compositions useful for occlusive medical devices and methods of making and using them
PendingUS20180028715A1Good contraceptive effectMaintain good propertiesSurgical adhesivesOintment deliveryDevice implantVas deferens
An occlusive device and a method of embolizing or occluding a bodily lumen by injecting or otherwise implanting the occlusive device are described. The device includes a polymer or polymer composition and a carbon-based material or nanomaterial such as graphene. The device may be used for sterilizing a human or animal by implanting the device into the vas deferens, fallopian tubes, or uterus, but may also be used to occlude any other bodily ducts, interstitial space, or organs.
Owner:CONTRALINE INC
Annular electrode array
ActiveUS20120259388A1Maintain biocompatibilitySpinal electrodesHead electrodesNeural controlElectrode array
A three-dimensional annular electrode array (AEA) device is disclosed for use as a cybernetic neural interface for the neural control and sensory feedback of a bionic prosthetic device. The AEA, designed for implantation into a nerve, is comprised of a body (6) that can be coupled to a sleeve(s) (9, 10) or a sleeve(s) with a compartmentalized inner core (12) for connection to the proximal and distal ends of a transected nerve, respectively. Regenerating nerve axons capture and sequester laterally projecting electrode terminals (4) arranged in radiating clusters (5) of a plurality of electrode sub-array nodes (2) that make up the array; connected by a primary electrode lead (7) to a connector contact array (3) in a plurality of connectors (1) for connection to wired or wireless electromechanical systems.
Owner:GALVAN GARCIA PEDRO
Process for preparing medical 3D chitosan material
A process for preparing medical 3-D chitosan material with certain shape used for setting up bone includes such steps as dissolving chitosan in 2% solution of acetic acid, filtering, laying aside forremoving bubbles, coating it on the inner surface of a mould, putting the mould in 3-8% coagulating luqid of sodium hydroxide to obtain a white gel layer used as template for chitosan in site assembling, filling the solution of chitosan in acetic acid into the said template, gradient neutralizing in the coagulating liquid to obtain longitudinal height ordered 3-D chitosan material, immersing in distilled water until it shows neutral, and vacuum drying. It can be used to make bone-setting nail or rod, or splint.
Owner:ZHEJIANG UNIV
Hydroxyphenyl cross-linked macromolecular network and applications thereof
InactiveCN101052684AShow mechanical propertiesWell representedPharmaceutical delivery mechanismPharmaceutical non-active ingredientsMolecular networkCross-link
A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic, implantable tissue matrix material for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.
Owner:THE CLEVELAND CLINIC FOUND
Preparation method of sensor electrode surface anti-biological-pollution coating
ActiveCN107976472ANon-immunogenicGood biocompatibilityMaterial electrochemical variablesEnvironmental resistanceFood safety
The invention discloses a preparation method of a sensor electrode surface anti-biological-pollution coating. The method is characterized by comprising two major steps of synthesizing photosensitive hyaluronic acid and preparing an anti-biological-pollution coating. The prepared photosensitive hyaluronic acid has high hydrophilcity, optical crosslinking performance and good biocompatibility. The synthesis of the photosensitive hyaluronic acid is simple; the raw materials can be easily obtained; the industrial production can be easily realized; through the introduction of photosensitive monomers, on the basis that the coating achieves the self excellent characteristics of the hyaluronic acid, the coating structure can be fixed through ultraviolet light crosslinking. When the photosensitivehyaluronic acid is applied to raw liquid sample detection, a sensor electrode based on modification by the photosensitive hyaluronic acid coating has long-term and efficient anti-biological-pollutioncapability. The light crosslinking technology, the functional coating technology and the biosensing technology are combined; the preparation method can be widely applied to the fields of food safety,biological medicine, environment protection monitoring, life safety and the like.
Owner:JIANGNAN UNIV
Bird's nest acid moisturizing and repairing nano composition, preparation method thereof and cosmetic
ActiveCN114159335APromote hydrationGuaranteed updateCosmetic preparationsToilet preparationsPolyolCutin
The invention relates to the technical field of cosmetics, in particular to a sialic acid moisturizing and repairing nano composition, a preparation method thereof and a cosmetic. The sialic acid moisturizing and repairing nano composition provided by the invention is prepared from the following components in percentage by mass: 0.1 to 20 percent of sialic acid, 0.1 to 20 percent of tetrahydromethylpyrimidine carboxylic acid, 0.1 to 10 percent of human collagen, 1 to 10 percent of liquid lipid, 1 to 20 percent of emulsifier, 1 to 20 percent of co-emulsifier, 1 to 20 percent of polyhydric alcohol and the balance of water. The sialic acid moisturizing and repairing nano composition provided by the invention not only has excellent moisturizing and hydrating effects, but also can firmly lock moisture stored in skin, repair cutin barrier, promote keratinocyte differentiation and skin renewal, and maintain normal functions of skin.
Owner:WUHAN BEST CARRIER NANO TECH +1
Modified polyactic acid and preparation method thereof
The invention discloses a modified polyactic acid and a preparation method thereof. The modified polyactic acid provided by the invention consists of a linear poly-L-lactic acid (PLLA) and a poly-dextro-lactic acid (PDLA) with a branched structure, wherein the PDLA with the branched structure is at least one of a stellate branched PDLA, a pectinate branched PDLA, a block copolymer of the stellate branched PDLA and a racemic polyactic acid and a block copolymer of the pectinate branched PDLA and the racemic polyactic acid. The modified polyactic acid is prepared by mixing the linear PLLA and the branched PDLA. In the preparation method, the PDLAs with different branched structures are added into the linear PLLA in a certain ratio; and the PDLA and the PLLA form a stereo composite. The PLLA and the branched PDLA are connected with each other by stereo composite structures, so that a net-like structure taking branched points and the stereo composite as crosslinking points is formed in the modified polyactic acid, and an excellent mechanical property is provided for the modified polyactic acid.
Owner:INST OF CHEM CHINESE ACAD OF SCI
Composite structure capable of retarding magnesium-alloy degradation under coating by silk fibroin
ActiveCN106512082AReduce the degradation rateConducive to repairTissue regenerationCoatingsBiocompatibility TestingStem cell
The invention discloses a composite structure capable of retarding magnesium-alloy degradation under coating by silk fibroin. The composite structure comprises a magnesium-alloy matrix, a surface modification layer and a silk fibroin film successively from inside to outside. The surface modification layer plays a role in connecting the magnesium-alloy matrix with the silk fibroin film and is prepared by immersing the magnesium-alloy matrix into an organic silylation solution. The magnesium-alloy matrix after silylation surface modification is immersed into an aqueous silk fibroin solution with the mass concentration of 1-10%; drying is carried out at a temperature of 30 to 150 DEG C for 30 to 120 minutes; and then the processed magnesium-alloy matrix is immersed into methyl alcohol for 2 to 12 hours to prepare the silk fibroin film. Therefore, under the circumstances that the magnesium-alloy mechanical property and biocompatibility are not affected, the magnesium-alloy degradation time can be retarded effectively and several kinds of stem cells like the mesenchymal stem cells and epidermic cells can be carried; and basic physiological activities like fission and differentiation can be promoted.
Owner:HARBIN MEDICAL UNIVERSITY +1
Phosphate radical containing cotton modification material and preparation method and application thereof
ActiveCN106637956ANo damage to mechanical propertiesMaintain permeabilityOther chemical processesPeptide preparation methodsCellulosePhosphate
The invention belongs to the field of analytical chemistry. A novel phosphate radical containing cotton modification material is prepared by adopting a graft copolymerization method. The phosphorus content of the material can be well controlled by adjusting the content of a monomer VPA, then metal ions are immobilized on the material, and the material can serve as a material for fixing metal affinity chromatography and used for selective enrichment of phosphorylated polypeptides in multiple biological samples. The optimal material CF-NH2-AZO-p(VPA-2)-Ti4+ can be optimized by researching the relation between the content of phosphate radical groups in the material and material extracting capability. The material has the high selectivity and high extraction capability to the phosphorylated polypeptides in a standard polypeptide mixed solution, milk enzymatic hydrolysate, serum and rat brain lysate. Therefore, application of the graft copolymerization method in cellulose post-modification can be promoted, and application of a cellulose adsorbent in bioanalysis is widened.
Owner:WUHAN UNIV
A kind of electroactive anticorrosion coating based on γ-polyglutamic acid and its preparation method
ActiveCN107740172BMaintain biocompatibilityRemain biodegradableElectrolytic coatingsCytotoxicitySolvent
The invention relates to an electroactivity anti-corrosion coating based on gamma- polyglutamic acid and a preparation method thereof. The electroactivity anti-corrosion coating not only has good anti-corrosion performance, but also can keep the original cell compatibility of base materials. The preparation method comprises the following steps of putting electro-active small molecular aniline tetramer through amidation reaction into natural poly-polypeptide gamma-polyglutamic acid, then carrying out self-assembly in selective solvent, and finally preparing the electro-active anti-corrosion coating on the surface of magnesium alloy through electrophoretic deposition technology. The electroactivity anti-corrosion coating can well adjust and control the degradation behaviors of the magnesiumalloy, and also has lower cytotoxicity and good cell compatibility. In addition, the whole preparation process is simple to operate, low in energy consumption, and wide in application range, and easily realizes industrialization.
Owner:JIANGNAN UNIV
Three-dimensional chitosan material preparation method
InactiveCN104800893AKeep aliveMaintain biocompatibilitySurgeryMaterial DegradationMaterials preparation
The present invention discloses a three-dimensional chitosan material preparation method, which comprises: 1) dissolving chitosan in a 10-15% dilute acetic acid solution to prepare a chitosan-dilute acetic acid solution with a concentration of 15-20%, filtering, and carrying out standing defoaming; 2) according to the required shape, uniformly coating the chitosan-dilute acetic acid solution on the inner surface of a corresponding mold, placing the mold into a sodium hydroxide solidification liquid with a concentration of 12-18%, and solidifying at a room temperature to obtain a layer of a white gel used as a chitosan in-situ self-assembly template; and 3) injecting the chitosan-acetic acid solution into the template, carrying out gradient neutralization in a sodium hydroxide solidification liquid with a concentration of 12-18%, carrying out in-situ self-assembly to obtain a longitudinal highly-ordered three-dimensional chitosan material, taking out, soaking with distilled water to achieve a neutral state, and carrying out vacuum drying. According to the present invention, the preparation method is simple, the conditions are mild, various shaped of bone knitting materials such as knit nails, knit rods, splints and the like can be made, and the non-infectious inflammations caused by the material degradation can be avoided.
Owner:江苏广达医材集团有限公司
Degradable polymer microsphere with surface concave pits and preparing method and application thereof
ActiveCN110448724AHigh degree of industrializationRemain biodegradableProsthesisPolymer scienceFoaming agent
The invention discloses a degradable polymer microsphere with surface concave pits and a preparing method and application thereof. The preparing method comprises the following steps of S1, dissolvinga degradable polymer into an organic solvent to prepare a degradable polymer solution; S2, adding the degradable polymer solution into an aqueous solution containing a surfactant, and after the materials are stirred for 15-45 minutes, adding a gas foaming agent; S3, continuing stirring the materials for 315-705 minutes, and then conducting washing and drying to obtain the degradable polymer microsphere with the surface concave pits. The prepared microsphere has good biocompatibility and degradability, is also provided with the surface concave pits suitable for cells to adhere to, and has a good application prospect in the field of tissue defect repairing and reconstruction.
Owner:GUANGDONG PROV MEDICAL INSTR INST
Preparation method of high-strength seaweed fiber
InactiveCN108221085AHigh strengthMaintain biocompatibilityAlginate artificial filamentsWet spinning methodsChemistryBiocompatibility Testing
Owner:安徽兴乐健身器材有限公司
Bioresorbable metal alloy and implants made of same
InactiveUS20170080121A1Improve functionalityMaintain biocompatibilitySurgeryTissue regenerationMetal alloyStrontium
Owner:UNIV OF FLORIDA RES FOUNDATION INC
Cathode mixture for use in a biocompatible battery
InactiveCN105390689AMaintain conductivityMaintain biocompatibilityEye implantsFinal product manufactureEngineeringBiocompatibility
The invention is named as a cathode mixture for use in a biocompatible battery. Methods and apparatus to form biocompatible energization elements (e.g. electroactive contact lenses) are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, use fields of the method and the apparatus can comprise any biocompatible devie or product of the energization elements.
Owner:JOHNSON & JOHNSON VISION CARE INC
A kind of preparation method of anti-biological pollution coating on sensor electrode surface
ActiveCN107976472BRaw materials are easy to getEasy to realize industrial productionMaterial electrochemical variablesUltraviolet lightsBiocompatibility
Owner:JIANGNAN UNIV
Flexible solar blind detector of small organic molecule-gallium oxide heterojunction and preparation method of flexible solar blind detector
PendingCN113113543AStay flexibleMaintain biocompatibilitySemiconductor/solid-state device testing/measurementSemiconductor/solid-state device detailsHeterojunctionEngineering
The invention belongs to the technical field of photoelectric conversion, and particularly relates to a flexible solar blind detector of a small organic molecule-gallium oxide heterojunction and a preparation method of the flexible solar blind detector. The detector comprises a PET / ITO flexible substrate, an a-GaO light absorption layer, an NPB layer, a first test electrode and a second test electrode, the PET / ITO flexible substrate comprises a PET layer and an ITO layer located on the PET layer; the a-GaO light absorption layer is positioned above the ITO layer deviating from the PET layer; and the NPB layer is located on the face, away from the PET / ITO flexible substrate, of the a-GaO light absorption layer. The second test electrode is positioned at one side, deviating from the PET layer, of the ITO layer; and the first test electrode is located at one side, deviating from the a-GaO light absorption layer, of the NPB layer, wherein the a-GaO light absorption layer and the NPB layer form an a-GaO / NPB heterojunction, and a built-in electric field is formed, so that photon-generated carriers are separated. The detector has the self-powered performance, is flexible, well meets the requirements of wearable devices, and has potential application prospects in the field of intelligent monitoring.
Owner:金华紫芯科技有限公司
Process for preparing medical 3D chitosan material
A process for preparing medical 3-D chitosan material with certain shape used for setting up bone includes such steps as dissolving chitosan in 2% solution of acetic acid, filtering, laying aside for removing bubbles, coating it on the inner surface of a mould, putting the mould in 3-8% coagulating luqid of sodium hydroxide to obtain a white gel layer used as template for chitosan in site assembling, filling the solution of chitosan in acetic acid into the said template, gradient neutralizing in the coagulating liquid to obtain longitudinal height ordered 3-D chitosan material, immersing in distilled water until it shows neutral, and vacuum drying. It can be used to make bone-setting nail or rod, or splint.
Owner:ZHEJIANG UNIV
Terminally modified polymers and conjugates thereof
InactiveUS20170119896A1Reduce degradationProlonged plasma half-lifeOrganic active ingredientsTetrapeptide ingredientsPolymer scienceMaterials science
A terminally modified polymer is provided herein. At least one terminus of the polymer is —O—(CH2)2-LM or —O—CH2—CH(OH)—CH2—CR1═CR2R3. LM, R1, R2, and R3 are defined herein Also disclosed are terminal conjugates comprising the polymer and a pharmaceutically useful modifier, as well as compositions comprising the conjugates, methods of their preparation, and methods of treating various disorders with the conjugates or their compositions.
Owner:MERSANA THERAPEUTICS INC
A kind of degradable polymer microsphere with surface pits and its preparation method and application
ActiveCN110448724BHigh degree of industrializationRemain biodegradableProsthesisPolymer scienceCell adhesion
The invention discloses a degradable polymer microsphere with surface pits and its preparation method and application. The preparation method includes the following steps: S1, dissolving the degradable polymer in an organic solvent to prepare a degradable polymer solution; S2 1. Add the degradable polymer solution into the aqueous solution containing surfactant, after stirring for (15-45) min, add gas foaming agent; S3, after continuing to stir for (315-705) min, wash with water and dry to obtain the obtained The degradable polymer microspheres with pits on the surface are described. The microspheres prepared by the scheme of the present invention not only have good biocompatibility and degradability, but also have surface pits suitable for cell adhesion, and have good application prospects in the field of tissue defect repair and reconstruction.
Owner:GUANGDONG PROV MEDICAL INSTR INST
Cathode mixture for use in a biocompatible battery
ActiveUS9577259B2Maintain biocompatibilityMaintaining electroconductivityEye implantsFinal product manufactureEngineeringCathode
Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.
Owner:JOHNSON & JOHNSON VISION CARE INC
A long-acting antibacterial gel dressing for surgical wounds and preparation method thereof
The invention belongs to the field of medical dressings, and particularly relates to a long-effective bacteriostatic gel dressing used for operative wounds and a production method thereof. The gel dressing comprises raw material components of bacterial cellulose, alginate, a phenytoin medicine, nano-silver particles, polyvinyl alcohol, hydroxypropyl cellulose, glycerin, sorbitol, deionized water and the like. By using the antibacterial active components of the phenytoin medicine, the nano-silver particles and the like in combination with the active components, for promoting wound healing, of the bacterial cellulose, the alginate and the like, the long-effective bacteriostatic gel dressing used for the operative wounds has a synergistic effect in the aspects of antisepsis, anti-inflammation, promotion of healing of the operative wounds and the like, and has the characters of being good in air permeability, high in water-retention rate, high in tenacity and the like, and through high energy ray irradiation sterilization, a gel product is clean and safe, and does not cause wound infection.
Owner:MUDANJIANG MEDICAL UNIV
a plant protection agent
ActiveCN103694049BInduced disease resistanceMaintain biocompatibilityBiocideFungicidesPolyvinyl alcoholPolyethylene glycol
The invention discloses a plant protection agent, which is prepared by coordination and complexation of Xanthomonas exopolysaccharide and copper inorganic salt, or by coordination and complexation of Xanthomonas exopolysaccharide and zinc inorganic salt. Or the Xanthomonas exopolysaccharide is coordinated and complexed with copper inorganic salt and zinc inorganic salt; specifically, the composition is composed of the following weight percentages: Xanthomonas exopolysaccharide 0.5-1.0%, copper sulfate 0.5% ~1.0%, zinc sulfate 0.5~1.0%, polyethylene glycol-4000 1%, polyvinyl alcohol 2%, polyvinylpyrrolidone 1%, distilled water 93.0~95.0%. The present invention overcomes the problem of poor mixing properties of inorganic copper preparations, so it is sprayed on the surface of crops to form a dense protective drug film, which can slowly release copper and zinc ions as plant nutrition, thereby ensuring that the "copper content" in the preparation is low, and overcomes the problem of The problem of copper damage caused by improper use of inorganic copper preparations or the aggravation of mite infestation has been solved.
Owner:GUANGXI UNIV
Lysine-chitosan resin and preparation method thereof
InactiveCN100417666CSimple componentsSimple manufacturing methodOrganic active ingredientsCosmetic preparationsCross-linkPolymer science
The present invention is lysine-chitosan resin and its preparation process, and relates to chitosan modifying technology with lysine. The lysine-chitosan resin consists of chitosan, glutaraldehyde and lysine simply. The preparation process of lysine-chitosan resin includes the first reverse suspending process to prepare chitosan microsphere, the subsequent cross-linking with glutaraldehyde as cross-linking agent to prepare cross-linked chitosan resin and final modification with lysine to prepare the lysine-chitosan resin. The lysine-chitosan resin has homogeneous granularity, rich pores, high acid and alkali resistance and excellent effect of adsorbing acid radical anion, amino acid and protein, is regenerable, and may be used widely in medicine, food, cosmetics, water treatment, chemical and other fields.
Owner:CHONGQING UNIV
Patellar scaffold and preparation method thereof
InactiveCN108888802AGood biocompatibilityImprove mechanical propertiesBone implantJoint implantsBiocompatibility TestingIn vivo
The invention relates to a patellar scaffold and a preparation method thereof. The patellar scaffold is made of magnesium alloy and comprises, by mass, 93-95% of Mg, 5-5.5% of Zn, 0.2-0.4% of Zr, and0.1-0.3% of Ti. Patellar structure is extracted by means of three-dimensional reconstruction to construct a patellar scaffold model; the specific magnesium alloy formulation is used as a raw materialto prepare the magnesium alloy patellar scaffold, having the advantages of good mechanical properties, in-vivo degradability, good biocompatibility, good bio-durability and the like. The need for bonereplacement for fractures, dislocations, osteonecrosis and the like in practical application is satisfied; the problems are solved that, for instance, original protheses mismatch with biological anatomical features, debris of the protheses causes harm, and the embedded implants are unable to degrade; the patellar scaffold has a good application prospect.
Owner:SHENZHEN INST OF ADVANCED TECH
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