A long-acting antibacterial gel dressing for surgical wounds and preparation method thereof

Abstract

The invention belongs to the field of medical dressings, and particularly relates to a long-effective bacteriostatic gel dressing used for operative wounds and a production method thereof. The gel dressing comprises raw material components of bacterial cellulose, alginate, a phenytoin medicine, nano-silver particles, polyvinyl alcohol, hydroxypropyl cellulose, glycerin, sorbitol, deionized water and the like. By using the antibacterial active components of the phenytoin medicine, the nano-silver particles and the like in combination with the active components, for promoting wound healing, of the bacterial cellulose, the alginate and the like, the long-effective bacteriostatic gel dressing used for the operative wounds has a synergistic effect in the aspects of antisepsis, anti-inflammation, promotion of healing of the operative wounds and the like, and has the characters of being good in air permeability, high in water-retention rate, high in tenacity and the like, and through high energy ray irradiation sterilization, a gel product is clean and safe, and does not cause wound infection.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a long-acting antibacterial gel dressing for surgical wounds and a preparation method thereof. Background technique [0002] Surgical wound infection refers to the inflammatory reaction caused by the infection of pathogenic bacteria in the surgical wound, which is one of the common postoperative complications of surgical patients. Wound infection is common after general surgery, especially in gastrointestinal tract and other contaminated operations. The reproduction of its flora may lead to wound infection, which will affect the growth of granulation tissue, cause delayed wound healing, and even cause infection of organs and tissues. Injuries increase the suffering of patients and increase the cost of treatment. With the improvement of the level of surgery and the progress of nosocomial infection management, most surgical wounds can heal well, but affected by various factors, so...

AI Technical Summary

Problems solved by technology

First, its mechanical strength is still insufficient compared to fiber-type antibacterial dressings; second, although some antibacterial ingredients have strong antibacterial properties, they still have certain cell or tissue organ toxicity.

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