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33results about How to "Lower MDA levels" patented technology
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Separation method of phenolic acid glucoside compounds in juglans regial L. mature seed diaphragma juglandis fructus and application
ActiveCN111704639AIncrease vitalityImprove SOD vitalityCosmetic preparationsOrganic active ingredientsChemical compoundColumn chromatography
The invention discloses a separation method of phenolic acid glucoside compounds in juglans regial L. mature seed diaphragma juglandis fructus and an application, and belongs to the technical field offoods. The method comprises the following steps of (1) performing extraction: crushing the juglans regial L. mature seed diaphragma juglandis fructus, and performing extraction with alcohol to obtainjuglans regial L. mature seed alcohol extracts; and (2) performing separation: performing column chromatography on the juglans regial L. mature seed alcohol extracts obtained in the step (1), sequentially performing eluting with ethanol of different concentrations, performing repeated purifying and eluting, and performing separation to obtain the phenolic acid glucoside compounds, wherein the phenolic acid glucoside compounds are 2-hydroxyl-5-methoxylphenyl-O-beta-D-glucopyranoside, 6-hydroxyl naphthyl-1,2- ( 2-O-beta-D-glucopyranoside) and 2,6-dihydroxy naphthyl -O-beta-D-glucopyranoside. Pharmacological experiments confirm that the three compounds have favorable antioxidant activity.
Owner:JIANGNAN UNIV +1
Application of cannabidiol to preparation of antiaging drug for pet dog
InactiveCN108272779AImprove immunityGood anti-aging effectHydroxy compound active ingredientsAntinoxious agentsDiseaseOxygen
The invention provides application of cannabidiol to preparation of an antiaging drug for a pet dog. The antiaging drug for the pet dog is one of an injection, a tablet, a granule or a capsule; the cannabidiol can effectively improve the body immunity of the pet dog, scavenge oxygen free radicals in the body, and inhibits lipid peroxidation, so that the anti-aging capability of the pet dog is effectively improved, and the application has an effect of preventing and treating the free radial related disease of the pet dog, and has an excellent application prospect for the antiaging drug for thepet dog.
Owner:KUNMING MEDICAL UNIVERSITY +1
Formula feed for pig fattening period and preparation method thereof
PendingCN109874940AImprove digestibilityPromote degradationFood processingAnimal feeding stuffAnimal scienceRapeseed
The invention discloses a formula feed for the pig fattening period.The formula feed is prepared from, by weight, 40-50 parts of fermented corn germ meal, 20-30 parts of rice bran, 15-20 parts of drydistiller's grains, 10-15 parts of rapeseed cake, 10-15 parts of bean cake, 12-16 parts of a Chinese herbal medicine preparation, 5-8 parts of fish meal, 4-6parts of meat and bone meal, 7-10 parts ofcorn oil, 1-2 parts of salt, 1-2 parts of green tea powder, 0.8-1.2 parts of fermented polysaccharides and a trace amount of additives.The invention further disclosesa preparation method of the formula feed for the pig fattening period.Accordingly, the fermented corn germ meal serves as the main feed material, the fermented corn germ meal has the functions of achieving digestion and absorption easily and promoting growth, the surface of the feed is wrapped with a layer of Chinese herbal medicine preparation,the obtained feed has the effects of achieving the anti-bacterial property, diminishinginflammation, enhancing immunity, maintaining the balance of gastrointestinal microflora and the like, the nutritional requirements of fattening pigs in the growth period can be fully met, the fattening pigs can grow rapidly, the meat quality is obviously improved, and the disease resistance is high.
Owner:新昌县大船畈生物科技有限公司
Control effect and mechanism of mangiferin on diabetic encephalopathy
InactiveCN102813645ANew pharmacological effectNew medical useOrganic active ingredientsNervous disorderWhite blood cellPharmacologic action
The invention relates to novel pharmacologic action of mangiferin, i.e., effects of mangiferin on preventing and treating diabetic encephalopathy. Mangiferin can obviously improve cognitive impairment caused by diabetes, remarkably reduce the level of advanced glycation endproducts (AGF) in the brain and expression of the acceptor RAGE thereof, substantially enhance activity and expression of glyoxalase 1 (Glo-1) in the brain, remarkably reduce the level of interleukin 1-beta (IL-1beta) and tumor necrosis factor alpha (TNF-alpha) in the brain, substantially improve the level of reduced glutathione (GSH) in the brain, remarkably reduce the level of malonaldehyde (MDA) in the brain, substantially improve the activity of superoxide dismutase (SOD) and the level of GSH in serum and substantially reduce the level of MDA in the serum. Mangiferin can be used for preventing and treating diabetic complications like diabetic encephalopathy.
Owner:XUZHOU MEDICAL COLLEGE
Chinese medicine injection for treating acute cerebral hemorrhage and preparation method thereof
InactiveCN1371740AReduce secondary damageInhibit lipid oxidationUnknown materialsBlood disorderAcorusMortality rate
The present invention discloses a Chinese medicine injection for curing acute cerebral hemorrhage. It is made of (by weight ratio) antelope horn 1-70, moutan root bark 4-164, acorus root 2-60 and gardenia fruit 10-120 as raw material. Said invention also discloses its preparation method, and said injection possesses the good therapeutic effect.
Owner:张平
Application of laminarin in preparation of medicaments or cosmetics for adjusting metabolism of collagen of skin
InactiveCN103142635AReduce contentAnti agingCosmetic preparationsOrganic active ingredientsAntioxidant capacityUltraviolet
The invention discloses an application of laminarin in preparation of medicaments or cosmetics for adjusting metabolism of collagen of skin. Experimental study proves that laminarin can obviously reduce the MDA level of a skin tissue under ultraviolet radiation, increase the contents of SOD, GSH-Px and CAT in the skin tissue and improve the antioxidant capacity of the skin tissue, can obviously thicken a dermis layer of the skin under the ultraviolet radiation and increase the content of total collagen of the skin, can obviously increase the content of I-type collagen mRNA (messenger ribonucleic acid) of the skin tissue, and can also reduce the activity of the collagen by inhibiting the content of the MMP (matrix metallo proteinase)-1mRNA of the skin tissue under the ultraviolet radiation, so that the degradation of the collagen is reduced, and aging of the skin is slowed down under the ultraviolet radiation.
Owner:GUANGXI MEDICAL UNIVERSITY
Method for preparing malus baccata leaf alcohol extract, and antioxidation and liver protection effects thereof
InactiveCN103393785ASignificant improvementSignificantly protectiveDigestive systemAntinoxious agentsAlcoholLiquid ratio
The invention provides a method for extracting and preparing a malus baccata leaf alcohol extract, and applications thereof on antioxidation and acute liver injury, the method is characterized by: weighting malus baccata leaves dried in the shade, crushing, adding 30-99% ethanol in a material and liquid ratio of 1:25-1:30, ultrasonically extracting for 30-90min in conditions of 40 DEG C, 40Hz and 250W, extracting for 1-5 times, filtrating and merging extracts, pressure-reduction condensing until to be a cream, and freeze-drying to obtain the malus baccata leaf alcohol extract. The invention further discloses the malus baccata leaf alcohol extract, which is rich in flavones and phlorizin, has antioxidation and free radical removal functions, has substantial improvement and protection effects for acute liver injury, makes effects on prevention, treatment and auxiliary treatment of hepatopathy, and particularly has a substantial effect on acute liver injury caused by peroxy like alcohol stimulation.
Owner:大连杰信生物科技有限公司
Drug for treating diabetes mellitus and preparation method for drug
InactiveCN104623380ASmall side effectsNo complicationsMetabolism disorderPlant ingredientsDiabetes mellitusSide effect
The invention relates to a drug for treating diabetes mellitus and a preparation method for the drug. The drug is prepared from the following raw materials in parts by weight: 27-33 parts of folium mori, 17-23 parts of bamboo leaves, 17-23 parts of purslane, 12-18 parts of dendrobes, 7-13 parts of Chinese yams and 2-8 parts of cordyceps sinensis. The drug disclosed by the invention can treat the diabetes mellitus with a remarkable curative effect, is small in toxic or side effects and free of complications, less in treatment cost, and has the advantages of being good in treatment effect, simple and convenient in preparation method.
Owner:田江南
Age-defying drug
InactiveCN105920104AImprove immunityImprove anti-aging effectAntinoxious agentsImmunological disordersDiseaseLiver tissue
The invention discloses an age-defying drug, made by mixing well 0.3-99.7 parts by weight of industrial hemp seed extract and 99.7-0.3 part by weight of industrial cannabine. Experiments prove that this drug composition can prolong half survival time, average life and highest life of fruit fly to different degrees, can significantly improve SOD and GSH-PX activity in brain, heart and liver of a model mouse and very significantly lower MDA level in brain, heart and liver tissues. The drug composition can improve body immunity, clear oxygen radicals in body, inhibit lipid peroxidation and defy age, can prevent and treat diseases related to free radicals and has a promising application prospect.
Owner:云南瑞酚生物科技有限公司
Preparation of macranthoin G in eucommia ulmoides, and application of macranthoin G in neuroprotective medicine
InactiveCN103553922AImprove the level ofAntagonistic injuryOrganic active ingredientsNervous disorderMacranthoin GDisease
The invention belongs to the technical fields of tree secondary metabolism active ingredients and natural medicines, and particularly relates to a method for preparing macranthoin G by taking medicinal tree seed eucommia ulmoides as a raw material, and use of the macranthoin G in preparation of a neuroprotective medicine. The macranthoin G is prepared from eucommia ulmoides tree plant materials as raw materials in manners of drawing, extracting and separating. Themacranthoin G is simple in preparation technology, low in cost, short in cycle and high in yield. An experiment proves that themacranthoin G plays a significant protection role on a model cell injury, and indicates that the macranthoin G can be applied to preparation of the neuroprotective medicine, so as to prevent and treat various neurodegenerative diseases.
Owner:TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
Applications of piceatannol 3-O'-glucoside or piceatannol 3-O'-glucoside derivatives
InactiveCN109288852AHigh activityLower MDA levelsNervous disorderHydroxy compound active ingredientsMedicineApoptosis
The invention belongs to the technical field of biological pharmacy, and especially relates to applications of piceatannol 3-O'-glucoside or piceatannol 3-O'-glucoside derivatives. It is shown by research that piceatannol 3-O'-glucoside or the piceatannol 3-O'-glucoside derivatives are capable of inhibiting excitatory amino acid toxicity, preventing nerve cell apoptosis, increasing nerve cell activity, reducing MDA level in nerve cells, and promoting nerve cell proliferation, and posses obvious protection effects on ALS cell models.
Owner:KPC PHARM INC
Application of notoginsenoside R1
InactiveCN103877107AFacilitate cognitionImprove mitochondrial functionOrganic active ingredientsNervous disorderDiseaseCognition
The invention relates to the field of medicines, and particularly relates to an application of notoginsenoside R1. Experiments prove that NTR1 can be used for improving the cognition, learning and memory capabilities of an APP / PS1 transgenic AD mouse, restoring the intracerebral ChAT level of the mouse, reducing the intracerebral malondialdehyde level, and improving the mitochondrial function of the AD mouse by improving the CcO activity. In addition, the NTR1 also can be used for increasing the IDE level so as to promote degradation of A beta and inhibit the accumulation of the A beta. Therefore, the invention further provides the application of the notoginsenoside R1 to preparation of a medicament for treating an alzheimer disease. Moreover, experiments prove that the notoginsenoside R1 causes no influences to cell viability within a concentration range of 0-500 micromoles, so the notoginsenoside R1 is proved to be safe in medication.
Owner:BEIJING NORMAL UNIVERSITY +1
Application of Quanmasu in preparation of anti-aging drugs
InactiveCN105935375AGood anti-aging effectImprove immunityAntinoxious agentsImmunological disordersDiseaseCannabis
The invention discloses application of Quanmasu in preparation of anti-aging drugs. The Quanmasu is prepared by uniform mixing of 0.3-99.7 parts by weight of an industrial hemp Fructus Cannabis extract and 99.7-0.3 parts by weight of industrial hemp Huomasu. Experiments prove that Quanmasu has different degrees of prolongation effect on the half survival time, average lifetime and maximum longevity of fruit fly, can significantly improve the activity of SOD and GSH-PX in model mouse brain, heart and liver, and significantly decreases the MDA level of brain, heart and liver tissue. Quanmasu can improve the immune ability of the body, scavenge oxygen free radicals in vivo and inhibit lipid peroxidation, can resist aging, has a control effect on free radical related diseases, and also has good application prospects.
Owner:云南瑞酚生物科技有限公司
Application of dioscin to preparation of medicines for treating Alzheimer's diseases
InactiveCN110755444ASafePracticalOrganic active ingredientsNervous disorderNerve cellsOxidative injury
The invention discloses an application of dioscin to preparation of medicines for treating Alzheimer's diseases. The Morris water maze testing result shows that a dioscin administration group can shorten the escaping latency period, prolong original platform quadrant residence time and increase the number of times of passing through a platform, which indicates that the dioscin can significantly improve the spatial learning and memorizing capacity of AD mice; the gait analysis result indicates that the dioscin can significantly increase the gait indexes of the AD mice, and strengthen the physical strength of the AD mice, so that the movement velocity of the AD mice is accelerated, the stride frequency is increased, the stepping length is increased and the duty cycle can be significantly shortened; the dioscin can significantly reduce the MDA level in hippocampal tissue of the AD mice, increase the GSH level and the SOD level, and improve oxidative damage of brain tissue of the AD mice;and the dioscin can restrain AchE activity of the hippocampal tissue, increase ChAT level, influence a cholinergic system, obviously improve the pathology structure of the brain tissue of the AD miceand ultrastructural damage of nerve cells. The dioscin can be used as a single effective component to be prepared into medicines, and can be combined with other medicines for preparing a compound preparation.
Owner:DALIAN MEDICAL UNIVERSITY
Chinese medicine injection for treating acute cerebral hemorrhage and preparation method thereof
InactiveCN1141136CLower MDA levelsDecreased SOA activityUnknown materialsBlood disorderAcorusTherapeutic effect
Owner:张平
A method for detecting signal of diabetic nephropathy and glomerular mesangial cells utilizing Dendrobium officinale
InactiveCN109200193AMild pathological changesReduces MDA levels in damaged tissuesOrganic active ingredientsMetabolism disorderCTGFSignalling pathways
The invention belongs to the technical field of traditional Chinese medicines, and discloses a method for detecting signal of diabetic nephropathy and glomerular mesangial cells utilizing Dendrobium officinale. Streptozotocin is adopted for induction to build a diabetic rat model, and the Dendrobium officinale particles with different dosages are administrated for 8 weeks, and changes in biochemical indexes and renal pathology of rats of each group are observed. HMC is cultured in vitro and added with normal concentration of glucose, mannitol, high glucose and different concentrations of Dendrobium officinale. Activity of p-38MAPK and downstream TGF-beta and CTGF expression are observed. The invention establishes the diabetic rat model, and uses different concentrations of Dendrobium officinale for treatment, the Dendrobium officinale can obviously reduce TGF-beta and CTGF expression levels in the HMC cells, and the Dendrobium officinale can achieve an anti-fibrosis effect through influencing the activity of the p-38MAPK signaling pathway to regulate downstream TGF-beta and CTGF expression.
Owner:SHANGQIU MEDICAL COLLEGE
Applications of Lactobacillus kefiri M11 in bacteriostasis and in the treatment of type 2 diabetes mellitus as an active ingredient of medicament
ActiveCN110141584AGood reliefImprove adhesionPowder deliveryMetabolism disorderEscherichia coliLactobacillus kefir
The invention discloses applications of lactobacillus kefir M11 in bacteriostasis and in the treatment of type 2 diabetes mellitus as an active ingredient of medicament. The invention solves the problems of low surface hydrophobicity and poor bacteriostasis ability of the existing lactic acid bacteria. The lactobacillus kefiriM11 of the invention has an obvious inhibitory effect on escherichia coli and staphylococcus aureus, with a good bacteriostatic effect. According to the invention, the lactobacillus kefir iM11 and a bacterial preparation thereof have excellent surface hydrophobicity and cohesion and a good adhesion ability to the intestinal tract, thus realizing a good blood sugar regulation ability in the application of type 2 diabetes mellitus. The invention has an obvious effect onalleviating symptoms of type 2 diabetes mellitus.
Owner:HEILONGJIANG UNIV
Health preserving tea with liver protecting function
The invention discloses health preserving tea with a liver protecting function. The health preserving tea comprises, by weight, 5-20 parts of engelhardia roxburghiana and 0.5-2 parts of morinda officinalis. During use, engelhardia roxburghiana and morinda officinalis are obtained, 600-1000 parts of water are added for soaking for 1-2 hours, the mixture is boiled with big fire and decocted for 0.5hour with soft fire, and then a decoction is obtained through filtering. The health preserving tea with the liver protecting function is safe to use, free of toxic and side effects and capable of protecting the liver and tonifying the kidney, avoids the problems of excessively high renal pressure or renal injury and the like during liver protection, can lower the MDA level, reduce the body oxidative stress and prevent cell injury and then protect the liver, and solves the problem of liver cell injury caused by various reasons.
Owner:YULIN NORMAL UNIVERSITY
A kind of medicine for treating diabetes and preparation method thereof
InactiveCN104623380BSmall side effectsNo complicationsMetabolism disorderPlant ingredientsDiabetes mellitusForest yam
The invention relates to a drug for treating diabetes mellitus and a preparation method for the drug. The drug is prepared from the following raw materials in parts by weight: 27-33 parts of folium mori, 17-23 parts of bamboo leaves, 17-23 parts of purslane, 12-18 parts of dendrobes, 7-13 parts of Chinese yams and 2-8 parts of cordyceps sinensis. The drug disclosed by the invention can treat the diabetes mellitus with a remarkable curative effect, is small in toxic or side effects and free of complications, less in treatment cost, and has the advantages of being good in treatment effect, simple and convenient in preparation method.
Owner:田江南
Extract for treating pelvic inflammation and preparation method thereof
ActiveCN108354998AHigh content of active ingredientsImprove whole blood viscositySexual disorderPlant ingredientsDiseaseSide effect
The invention relates to an extract for treating pelvic inflammation as well as a preparation method and application thereof. The extract is prepared from the following traditional Chinese medical materials in parts by weight: 600 to 1000 parts of herba melastomatis dodecandri, 180 to 300 parts of radix zanthoxyli, 150 to 260 parts of radix angelicae sinensis, 120 to 200 parts of radix fici simplicissimae and 150 to 230 parts of root of cudrania tricuspidata Bun. The active ingredients are herba melastomatis dodecandri alcohol water extracts, radix zanthoxyli alcohol water extracts, radix angelicae sinensis alcohol water extracts, radix fici simplicissimae alcohol water extracts, root of cudrania tricuspidata Bun alcohol water extracts. The extract is prepared through the methods of waterextraction, ethanol extraction and the like. The extract has the advantages of high active ingredient content, small medicine taking dose and no toxic and side effects; the exact curative effect is achieved in aspects of treating common gynecological diseases such as acute and chronic pelvic inflammation.
Owner:ANHUI JINGFANG PHARMA
Astaxanthin long-acting nano preparation prepared through micelle template method and preparation method for astaxanthin long-acting nano preparation
ActiveCN113244190ASolve insolubleReduce releaseOrganic active ingredientsDigestive systemAstaxanthinPhospholipid
The invention discloses an astaxanthin long-acting nano preparation prepared through a micelle template method and a preparation method for the astaxanthin long-acting nano preparation, and relates to the field of nano pharmaceutical preparations. Phospholipid and sodium cholate are used as micelle templates, and a solubilizing and synergy carrier is provided for insoluble compound astaxanthin; the novel astaxanthin micelle-loaded PLGA nano preparation is prepared from astaxanthin, phospholipid, sodium cholate and PLGA in a mass ratio of 1: (3-7): (2-5): (10-50) through an emulsion solvent evaporation method by taking a polylactic acid-glycolic acid copolymer as a long-acting carrier, wherein the ratio of a total organic phase to a total water phase is 1: (5-25). According to the preparation, on the premise that the solubility of the astaxanthin is remarkably improved, the long-acting liver protection effect of the astaxanthin is achieved at the same time. The process is simple, the micelle template is innovatively applied to preparation of the insoluble medicine long-acting preparation, and has a good application prospect.
Owner:JIANGSU UNIV
Preparation of macranthoin G in eucommia ulmoides, and application of macranthoin G in neuroprotective medicine
InactiveCN103553922BImprove the level ofAntagonistic injuryOrganic active ingredientsNervous disorderDiseaseMacranthoin G
Owner:TIANJIN UNIV OF SCI & TECH
Novel application of Jingzhaotoxin
ActiveCN102205113BHigh activityGood restorativeNervous disorderPeptide/protein ingredientsCerebrovascular disorderCyclooxygenase
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV
Novel application of Jingzhaotoxin
ActiveCN102205113AHigh activityGood restorativeNervous disorderPeptide/protein ingredientsCerebrovascular disorderCyclooxygenase
The invention discloses novel applications of Jingzhaotoxin, and particularly relates to an application of Jingzhaotoxin in a medicament for treating and / or preventing cerebrovascular disorder (apoplexy) and an application of Jingzhaotoxin in a medicament for preventing and / or treating nerve injuries. According to the invention, the Jingzhaotoxin has a remarkable repairing effect on nerve injuries, such as anticoagulation, free radical removal [superoxide dismutase (SOD) activity reinforcement, malondialdehyde (MDA) level reduction, inflammation cyclooxygenase-2 (COX-2) transcriptional level reduction and other applications are included], ischemic stroke symptom relief, cerebral infarction area reduction and the like.
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV
Application of Liquidamia hordgsonii Hook. polysaccharide in preparation of drugs for treating and/or preventing liver diseases
InactiveCN112089725ALower serum AST valueLower MDA levelsOrganic active ingredientsDigestive systemPyrroleSenecio Alkaloids
The invention belongs to the field of traditional Chinese medicines, and relates to an application of Liquidamia hordgsonii Hook. polysaccharide in preparation of drugs for treating and / or preventingliver diseases. A rat liver injury model induced by carbon tetrachloride and clivone (endogenous hepatotoxin pyrrolizidine alkaloid) is adopted, the liver protection effect is investigated, and the result shows that the Liquidamia hordgsonii Hook. polysaccharide can significantly reduce the liver function index and the oxidative stress index of a liver injury rat, can be used for research and development of safe and effective liver protection drugs, and especially can be used for prevention and treatment of traditional Chinese medicine-derived liver injury drugs caused by pyrrolizidine alkaloid. The application has important significance for reasonable development and utilization of the Sichuan Chinese herbal medicine Liquidamia hordgsonii Hook.
Owner:WUHAN UNIV
Application of nadph and vitamin E in combination for preparing medicine for preventing or treating liver injury
ActiveCN112587541BReduce contentLower MDA levelsOrganic active ingredientsDigestive systemAlanine aminotransferasePharmaceutical Substances
The invention belongs to the field of biomedical research, in particular to the application of NADPH and vitamin E in combination for preparing a medicine for preventing or treating liver damage. NADPH and vitamin E can play a synergistic effect within a certain dose range, and have a good protective effect on liver damage caused by carbon tetrachloride, not only can significantly reduce aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphate Enzyme (ALP) and total bilirubin (TB) content, and can increase the content of ATP in hepatocytes, reduce the levels of MDA in hepatocytes and serum, increase the levels of SOD and GSH in hepatocytes and serum, and increase the levels of SOD and GSH in hepatocytes. CAT level. It was also proved by cell experiments that the combination of NADPH and vitamin E could significantly reduce the decrease in the survival rate of liver cells in the liver injury model induced by CCl4, thereby playing a role in preventing or treating liver injury.
Owner:SUZHOU UNIV
Environment-friendly fresh-keeping agent formula for waxberries and preparation method of environment-friendly fresh-keeping agent formula
PendingCN112120077AEfficient removalDoes not harm the human bodyFruit and vegetables preservationYeast food ingredientsPumpkin seedAspergillus niger
The invention discloses an environment-friendly plant fermentation fresh-keeping preparation. The environment-friendly plant fermentation fresh-keeping preparation is prepared by fermenting organic biological components and beneficial bacteria in a matched manner, wherein the organic biological components comprise artemisinin, torreya grandis, pumpkin seeds, chitosan and mannan; and the beneficialbacteria comprise saccharomycetes, aspergillus niger and bacillus subtilis. The selected organic biological components are appropriate in proportion and reasonable in component structure; and throughprimary fermentation and secondary fermentation, the fresh-keeping effect is remarkably improved by 4-22 times. The fermentation fresh-keeping preparation can permeate deep into the skins of waxberries and efficiently kill pathogenic microorganisms and parasites, relatively high SOD level of the waxberries is kept, rotten components MDH of the waxberries are reduced, and the shelf life of the waxberries is effectively prolonged.
Owner:王虎
Composition and application for alleviating degenerative neuropathy
ActiveCN111529545BImprove motor dysfunctionImprove distributionSugar food ingredientsNervous disorderGlycineTyrosine
Owner:SICHUAN AGRI UNIV +1
Application of a kind of angelica protein in the preparation of liver injury protection medicine
ActiveCN108610397BSignificant proliferative effectLower MDA levelsPeptide/protein ingredientsDigestive systemAST activityPharmaceutical drug
The invention relates to the field of natural Chinese herbal protein, in particular to application of angelica protein to preparation of a medicine for protecting against acute liver damage. The N-terminal sequence of the angelica protein is GIQKTEVEAPSTVSA. The angelica protein has a significant proliferative effect on normal liver cells L-02, and at the dosage of 0.5mg / mL, the proliferation rateof L-02 cells can reach 163.114%. The angelica protein is applied to preparation of the medicine for preventing the liver damage, can significantly improve the CAT, GST and T-AOC activity of the liver of a damaged mouse and significantly reduce the MDA level of the liver, significantly improves the liver cell necrosis of the liver of the damaged mouse, thereby significantly reduces the blood ALTand AST activity and liver indexes of the damaged mouse to the normal group levels basically, and thus significantly reduces damage of CCl4 to the mouse liver.
Owner:FUZHOU UNIV
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