The invention belongs to the dosimeter calibration technology field, and discloses a gamma ray irradiation device used for thermoluminescence personal dosimeter calibration. The irradiation device comprises an irradiation system, a positioning system, a transmission system, and a control system. The irradiation system, the positioning system, and the transmission system are disposed in the same housing. The irradiation system is disposed on the upper part of the transmission system, and the positioning system is disposed on one side of the transmission system. The control system comprises a computer, a PLC special controller, a positioning sensor, and an irradiation controller. The computer and the PLC special controller are used to independently realize the control over the gamma ray irradiation device, and the positioning, the transmission, and the irradiation of the thermoluminescence personal dosimeter are realized automatically. The gamma ray irradiation device has advantages of high calibration efficiency, low calibration place requirement, good automatic shielding effect, and ability of realizing automatic calibration.