309 results about "LIGHT STIMULATION" patented technology

The present invention concerns a device and method for transmitting multiple optically-encoded stimulation signals to multiple stimulation sites, especially cell locations. The device uses a primary optical fiber to transmit specific wavelength components of an encoded light signal to output positions along the fiber where they are coupled out of the primary fiber to stimulation sites via electrodes for electrical stimulation of the sites or optical windows and / or secondary optical fibers for photo-stimulation of sites.

The present invention comprises systems and methods for stimulating target tissue comprising a light source; an implantable light conducting lead coupled to said light source; and an implantable light-emitter. The light source, lead and emitter are used to provide a light stimulation to a target tissue

The present invention concerns a device and method for transmitting multiple optically-encoded stimulation signals to multiple stimulation sites, especially cell locations. The device uses a primary optical fiber to transmit specific wavelength components of an encoded light signal to output positions along the fiber where they are coupled out of the primary fiber to stimulation sites via electrodes for electrical stimulation of the sites or optical windows and / or secondary optical fibers for photo-stimulation of sites.

An apparatus for administering light to effect re-timing of the human body clock is disclosed. In one form, the apparatus includes two pairs of light emitting diodes having an emission wavelength in the range 450 nm to 530 nm and a frame adapted to be worn on the face of a wearer. The frame is arranged to support the two pairs of light emitting diodes so that one pair of the light emitting diodes is supported adjacent a surface of each eye of the wearer. The light emitting diodes of each pair project a light output that illuminates a different area of the retina of a respective eye and are spaced apart so as to provide a viewing zone therebetween.

The present invention describes methods and devices comprising magnetic, radio frequency burst, and light stimulation to modulate muscle contraction. The magnetic stimulation may be delivered to the muscle using one or more coils that is placed transcutaneously. The methods and devices are useful to treat a number of conditions or disease conditions, including for example, gastroesophageal cramps and sphincter leakage.

The invention relates to a multi-channel light stimulation-based cochlear implant device. The device comprises a multi-channel light stimulation device, a multi-channel light pulse control circuit, a voice signal acquisition deice and a voice signal processing and encoding device, wherein the device acquires a voice signal and encodes the voice signal into a light stimulation signal; and the light stimulation signal stimulates cochlear auditory nerve through a cochlea-implanted multi-channel light pulse output port to cause nerve impulse so as to form hearing in a central nervous system. The multi-channel light stimulation-based cochlear implant solves the problem of compatibility of a stimulating electrode and biological tissue in the electronic cochlear implant and also solves the problem of mutual interference between stimulating channels caused by current diffusion in the tissue.

A soundhead of a treatment device is provided that enables a volume of tissue located beneath the soundhead to simultaneously receive ultrasound and light stimulation. According to one embodiment, the soundhead includes an ultrasound transducer, a light source, and a faceplate extending across a face of the transducer for providing a tissue contacting and ultrasound energy coupling surface of the soundhead. The faceplate is transparent or translucent to the light generated by the light source. Alternate embodiments including externally mounted light sources are also disclosed.

The invention provides an LED optical stimulation and electrographic recording integrating flexible neural electrode device and a manufacturing method thereof. The device comprises an optical stimulation electrode and a recording electrode, wherein both the optical stimulation electrode and the recording electrode comprise bottom polymer insulating layers, top polymer insulating layers and middle gold circuit layers; a plurality of holes are formed in the bottom polymer insulating layers and the top polymer insulating layers; steel pins sequentially run through the holes in the optical stimulation electrode and the recording electrode; and when the optical stimulation electrode and the recording electrode are in gluing connection, the optical stimulation electrode and the recording electrode are prevented from becoming displaced. According to the method, the optical stimulation electrode and the recording electrode are independently manufactured, and then the optical stimulation electrode and the recording electrode are bonded. According to the flexible neural electrode device disclosed by the invention, on the basis of direct contact between LED and brain tissues, light transparency is guaranteed, and meanwhile, influence on recording results due to a photoelectric effect between light and the recording electrode is effectively avoided; the electrodes, which are relatively thin, can guarantee shape preservation when attached to cerebral cortex; and the requirements of acute experiments and long-term implant experiments can be satisfied.

The invention provides polynucleotides and methods for expressing light-activated proteins in animal cells and altering an action potential of the cells by optical stimulation. The invention also provides animal cells and non-human animals comprising cells expressing the light-activated proteins.

The invention discloses a light control and neural information detection system. The system comprises a light stimulation control module, an electrochemical detection module, an electrophysiological detection module, a synchronous data acquisition module, a main control module and a synchronous control module, wherein the light stimulation control module can be combined with the optogenetics technology to carry out light control via laser fibers or LED lamp electrodes; the electrochemical detection module is used for detecting neurochemical signals; the electrophysiological detection module is connected with a microelectrode array and is used for detecting neural electrophysiological signals; the synchronous data acquisition module is used for synchronously acquiring neural electrochemical and electrophysiological signals; the main control module is used for carrying out synchronous coordinated control on light stimulation and neural signal detection and completing data communication; the synchronous control module is used for completing the functions of man-machine interaction, data processing, display, analysis and storage, and the like. The system can be used for solving the problems that light control and signal detection are difficult in synchronous and experiment operation is fussy in the research on neurosciences.

A photocurable composition of the present invention to be used for manufacturing a film with high productivity is a photocurable composition to be used for manufacturing a film having a predetermined pattern shape by curing the photocurable composition with light under a state where the photocurable composition is brought into contact with a mold having concavo-convex on a surface thereof, the photocurable composition including: a polymerizable compound; a photopolymerization initiator; a photosensitive gas generating agent for generating a gas through light stimulation; and a gas generation promotor for increasing an aggregation rate of the gas generated from the photosensitive gas generating agent at an interface between the mold and the photocurable composition, in which the gas generation promotor includes a fluorine atom-containing surfactant that is free of a polymerizable substituent.