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406results about How to "Synergistic effect" patented technology

Targeted chimeric molecules for cancer therapy

The present invention concerns chimeric cancer therapeutic molecules comprising a targeting moiety and an anti-cell proliferation moiety. The anti-cell proliferation moiety may comprise a cytotoxic agent or an apoptosis-inducing factor, in specific embodiments. In particular embodiments, the anti-cell proliferation mechanism of the chimeric molecules comprises apoptotic pathways. In additional embodiments, the chimeric molecules of the present invention provide sensitivity to chemotherapy in a cell that is resistant to the chemotherapy.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

Organopolysiloxane combination for surface treatment, powder treated with the combination and cosmetic comprising the power

A combination for surface treating powder, composed of (I)organopolysiloxane or condensate thereof and (II)organopolysiloxane in a weight ratio of (I):(II) of from 95:5 to 5:95; (I)organopolysiloxane or condensate thereof and (III) acryl/silicone copolymer in a weight ratio of (I):(III) of from 95:5 to 5:95; or (I)organopolysiloxane or condensate thereof, (II)organopolysiloxane and (III) acryl/silicone copolymer in a weight ratio of (I):[(II)+(III)] of from 95:5 to 5:95, provided that each of (I), (II), and (III) may be packed together or separately, wherein (I)organopolysiloxane is represented by the following formula (1),
R1a(OR2)bSiO(4-a-b)/2  (1)
wherein R1 may be the same with or different from each other and is a C1-30 alkyl, aryl, aralkyl, fluorinated alkyl or amino-substituted alkyl group,
  • R2 is a C1-6 alkyl group, a is the number of from 0.75 to 1.5, and b is the number of from 0.2 to 3, provided that a sum of a and b is greater than 0.9 and at most 4; (II)organopolysiloxane is represented by the formula (2)
R3cR4dR5eSiO(4-c-d-e)/2  (2)
wherein R3may be the same with or different from each other and is a C1-30 alkyl, aryl, aralkyl, or fluorinated alkyl group,
  • R4 is a hydrogen atom, a hydroxyl group or a C1-6 alkoxy group and is bonded to the Si atom in the formula (2) via a group comprising carbon, oxygen, or silicon atom, and
  • R5 is a silicone compound residue represented by the following formula
  • wherein R3 is as defined above, c is the number of from 1.0 to 2.5, d is the number of from 0.001 to 1.5, and e is the number of from 0 to 1.5, x is an integer of from 1 to 5, and y is an integer of from 0 to 500; and (III) acryl/silicone copolymer has at least one hydrolyzable silyl group.
    Owner:SHIN ETSU CHEM IND CO LTD

    Environmentally-friendly, energy-saving and fireproofing lightweight roof panel, floor plate or wallboard

    The invention relates to an environmentally-friendly, energy-saving and fireproofing lightweight roof panel, floor plate or wallboard, which comprises an upper surface layer, a lower surface layer and frame ribs. Insulating layers are arranged between the upper surface layer and the lower surface layer, and are cement polymer foamed plastic powder lightweight insulating plates or are formed by compounding the cement polymer foamed plastic powder lightweight insulating plates and any one of molded polystyrene foam plates, extruding-molded polystyrene foam plates and rock-wool slabs respectively; fiberglass alkaline-resistant mesh fabric is arranged in the upper surface layer and the lower surface layer; the frame ribs are fixedly connected to the lower surface layer; and an anticorrosion steel reinforcement frame is arranged in the frame ribs. In the environmentally-friendly, energy-saving and fireproofing lightweight roof panel, floor plate or wallboard of the invention, the lightweight insulating plates and lightweight surface layer mortar are manufactured by foamed plastic powder; the foamed plastic powder and heat-preservation foamed plastic form particles are applied to lightweight concrete; and materials for the upper and lower surface layers and the frame ribs are enhanced by two or more assorted fibers so as to fulfill the aims of lightweight, high strength, energy saving, sound insulation, fireproofing, crack resistance and durability.
    Owner:辽宁际洲环保节能建材有限公司

    Sugar Replacement and Baked Goods and Caramels Using the Sugar Replacement

    A sugar replacement includes a mixture of agave inulin and agave fructose. The agave inulin forms from 40 to 90 percent by weight of the sugar replacement. The agave fructose forms a remainder (10 to 60 percent by weight) of the sugar replacement. The sugar replacement has reduced calories and glycemic index compared to sugar. The sugar replacement can have its sweetness adjusted so that it is a one to one replacement for sugar. This is particularly useful when the sugar replacement is being used in baking recipes. Baked goods and caramels using the sugar replacement have qualities like those using sugar. The sugar replacement can be used to make chocolates.
    Owner:SWEETABUE

    Surface enhanced Raman scattering substrate, preparation method therefor and application thereof

    The invention discloses a ZnO-Ag surface enhanced Raman scattering substrate and detection of organic pollutants with the substrate. The preparation method for the substrate comprises the following steps: the first step, ITO conductive glass is subjected to ultrasonic cleaning with acetone, alcohol and deionized water one by one and dried in the air; the second step, organic additives are added in a zinc nitrate solution, a first mixed liquid is formed, after the first mixed liquid is stirred for 30 min, an ammonia-water solution with a mass fraction of 25% is dropwisely added in the first mixed liquid, a second mixed liquid is formed, the processed ITO conductive glass from the first step is soaked in the second mixed liquid, after the water bath is at a constant temperature, the ITO conductive glass is placed in a baking box and baked for 60-100 min, a white and uniform ZnO layer is formed on the surface of the ITO conductive glass; the third step, Ag nanoparticles are deposited on the prepared ZnO nanolayer from the second step, and a ZnO-Ag surface enhanced Raman scattering substrate is obtained. The preparation method is simple. The prepared substrate has high sensitivity and good stability and can be used repeatedly.
    Owner:INST OF CHEM MATERIAL CHINA ACADEMY OF ENG PHYSICS

    Sorghum wine and preparation method thereof

    The invention provides sorghum wine and a preparation method thereof. The preparation method comprises the following steps of: selecting sorghums not to be peeled, boiling in water till sorghum peels are broken, and filtering to obtain peel broken sorghums; steaming the peel broken sorghums to obtain cooked sorghums; adding distiller yeast into the cooked sorghums, and fermenting at 30-40 DEG C for 72-90h so as to obtain fermented sorghums; and immersing the fermented sorghums by using sorghum liquor for 5-9 days, and taking out supernate to obtain the sorghum wine, wherein in terms of weight, the proportion of the sorghums, the distiller yeast to the sorghum liquor is 1:(0.0015-0.002):(1.2-1.6). According to the invention, the traditional sorghum liquor is deeply processed; the nutritive value and the mouth feel are improved; furthermore, by uniquely adopting the steaming and boiling combined manner, the extraction rates of nutritional components are increased; the fermentation effect is improved; simultaneously, the high-quality fermented sorghums are obtained by adopting a unique fermentation condition; and the high-quality fermented sorghums can be mutually fused with the sorghum liquor so as to generate synergistic effects.
    Owner:熊仁义

    Anti-inflammation and allergy-relieving repair composition and preparation method and application thereof

    The invention discloses an anti-inflammation and allergy-relieving repair composition and a preparation method and an application thereof. The composition consists of a cactus extract, an oat bran extract, a sophorae flavescentis extract, an ophiopogon japonicus root extract, a peony root extract, a scutellaria baicalensis root extract, butanediol, pentanediol and water. The preparation method comprises the following steps: 1) preparing a sophorae flavescentis extract solution; 2) carrying out super-high pressure homogenization of the cactus extract, the oat bran extract, the ophiopogon japonicus root extract, the peony root extract, the scutellaria baicalensis root extract, butanediol and pentanediol to obtain a plant extract mixed solution; and 3) carrying out mixing, super-high pressurehomogenization and filtration of the plant extract mixed solution and the sophorae flavescentis extract solution. The anti-inflammation and allergy-relieving repair composition has anti-inflammatory,anti-allergic and analgesic effects, can enhance skin barrier function, enhances the skin self-protection ability, effectively repairs inflammatory skin, especially skins suffered from hormone-dependent dermatitis and cannot produce drug resistance, dependence and side effects after being used for a long time.
    Owner:中科厚朴(广州)科技发展有限公司 +1

    Soil improvement and anti continuous cropping multifunctional biological agent

    The invention provides a soil improvement and anti continuous cropping multifunctional biological agent which contains the mixed microorganism of trichoderma pseudokoningii and bacillus subtilis, faveolate humic acid and zinc sulphate; the trichoderma pseudokoningii is a bacterial strain obtained by separating and screening maize straw; the bacterial strain is named after (Trichoderma pseudokoningii) DLDI and is preserved in China general microbiological culture collection (CGMCC), and the number thereof is CGMCC NO.3221; the bacillus subtilis obtained by separating soil is named after (bacillus subtilis) DLD2 and is preserved in China general microbiological culture collection (CGMCC), and the number is CGMCCNO.3222; the biological agent has the effects that (1) biocontrol microorganism is used for blocking harmful flora from infecting plants and killing pathogenic bacteria, induces the plants to generate disease resistance and prevents dead seedlings from rotting roots; (2) the microorganism and the faveolate humic acid are compounded to induce the root system to grow, thus realizing root regeneration and plant regeneration and inhibiting the anti continuous cropping diseases; and (3) the faveolate humic acid and the zinc sulphate are used for breaking the soil hardening of the soil, forming the crumble structure, realizing no deep ploughing, retaining water, alleviating fertilizer damage and increasing the soil productivity.
    Owner:山东多利德生物科技有限公司

    Crystal mochi preblended flour, crystal mochi and preparation method thereof

    InactiveCN105558755AExcellent acid and high temperature resistanceExcellent mechanical shear resistanceFood scienceSodium dehydroacetateMaltitol
    The invention relates to the technical field of food and in particular discloses crystal mochi preblended flour, crystal mochi and a preparation method thereof. The crystal mochi preblended flour is prepared from the following raw materials in parts by weight: 10-15 parts of hydroxypropyl distarch phosphate, 8-13 parts of acetylated distarch phosphate, 0.5-0.7 part of maltitol, 0.2-0.4 part of monoglyceride, 0.04-0.06 part of sodium dehydroacetate and 0.04-0.06 part of citric acid. The crystal mochi is characterized in that a wrapper of the crystal mochi is prepared from raw materials, namely the crystal mochi preblended flour disclosed by the invention, water, emulsified oil and malt syrup. The mochi disclosed by the invention does not harden during storage, has good freeze-thaw stability, does not crack or collapse after being thawed, can maintain the original smooth and glutinous tastes and is long in quality guarantee period; and the prepared mochi is glittering and translucent in appearance and is soft, strong and not sticky and does not stick the mouth when entering the mouth, and the prepared mochi has good elasticity.
    Owner:HENAN HENGRUI STARCH TECH CO LTD

    Water soluble, randomly substituted partial N-partial O-acetylated chitosan, preserving compositions containing chitosan, and processes for making thereof

    The present invention is directed to a water soluble, randomly substituted partial N-, partial O-acetylated chitosans or chitosan derivatives and methods of preparing water soluble, randomly substituted partial N-, partial O-acetylated chitosans or chitosan derivatives comprising the steps of dissolving the chitosan or chitosan derivative into an aqueous acidic solution and reacting the chitosan or chitosan derivative with an acetylating agent in the presence of a phase transfer reagent. The present invention is further directed to a pharmaceutical preserving composition comprising: (a) at least one chitosan or chitosan derivative and (b) at least one buffer solution, as well as methods of preserving contact lens solutions and disinfecting contact lens using such composition.
    Owner:ADJUVANT PHARMA

    Compositions and methods for treating hepatitis-C

    InactiveUS6281191B1High purityLess gmdpBiocideAntiviralsIsoglutamineAminosugar
    New compositions and methods for treating patients suffering from hepatitis-C, AIDS, aberrant apoptosis which include N-acetyl-D-glucosaminyl(beta-1-4)-N-Acetyl-muramyl-L-ananyl-D-isoglutamine (GMDP) of at least 98% purity and provided either alone, as an active ingredient of blastolysine, or in combination with an aminosugar such as N-acetyl-glucosamine(NAG). The high purity GMDP has a decreased amount immunogenic impurities and demonstrates cell protection as opposed to solely immunostimulatory effects, while a synergistic cell protective effect is exhibited when GMDP in combined with NAG. The new compositions modulate FasL mediated apoptosis while simultaneously stimulating TNF-alpha production and further selectively inhibiting TNF-alpha receptor p55 (TNFR1), providing a treatment for patients suffering from hepatitis-C, AIDS or aberrant apoptosis.
    Owner:ZYLACTA CORP

    Corrosion inhibitor composition

    InactiveCN102965090AHigh corrosion inhibition performanceSynergistic effectBorehole/well accessoriesChemistryPolyaspartic acid
    The invention discloses a corrosion inhibitor composition, which includes a main agent and a compounded agent. The main agent is selected from the group consisting of oleic acid based imidazoline, naphthenic imidazoline, and bis-imidazoline. The compounded agent is selected from amino tris(methylene phosphonic acid), hydrolyzed polymaleic anhydride, sodium of polyaspartic acid and 2-phosphonobutane-1, 2, 4-tricarboxylic acid. Specifically, the main agent and compounded agent are in a mass ratio of 1:5-5:1. The corrosion inhibitor composition provided in the invention is compounded by the main agent and the compounded agent in a reasonable proportion, and a synergistic effect is achieved.
    Owner:NORTHWEST UNIV
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