A
system and methods are provided for the
therapeutic treatment of brain-plaques, fibrils, abnormal-
protein related or aggregation-prone
protein related deposition-diseases. The
system employs acoustic
exposure therapy means for delivering therapeutic energy to at least one
brain region. The therapy supports at least one of the following processes: (i) physical
breakup,
erosion, disentanglement, de-aggregation,
dissolution, de-agglomeration, de-amalgamation or
permeation of the deposits, (ii) interference in at least one deposit formation process, deposition related
chemical reaction or biological or genetic pathway contributing to the deposits or deposition-related processes, and (iii) aiding the
recovery, growth, regrowth or improved functionality of brain-related cells or functional pathways negatively impacted by, stressed by or disposed to the deposits, deposition-processes or deposition
disease state, or supporting the growth of newly transplanted cells anywhere in the brain-related
anatomy. The
system and methods treat Alzheimer's and other deposition-related disorders of the brain, with minimal adverse side effects to the patient and may be used in cooperation with a
drug.