50 results about "Superficial wounds" patented technology

The invention relates the medical biomaterial technology field. The existing clinical hemostasis dressing is only used for stopping blood, while the new biological dressing is only used for cleaning and healing superficial wounds and lacks a specific direction for treating posttraumatic wound, in particular, sea battle injury. The aim of the invention is to provide a method for preparing a hemostasis dressing with good volume expansibility, permeability, as well as obvious direction to deal with high-permeability seawater. The method for preparing the hemostasis dressing uses sodium alginate mixed by chitosan and various Na<+> / Ca<2+> as the basic material to form a hemostasis sponge with good mechanical strength after being cooled and dried, and prepares asymmetric seawater hemostasis dressing with porous layer and compact layer by using polyvinyl alcohol as the surface coating material. The dressing shows high expansibility and good permeability according to the results of volume expansibility, permeability and sem observation, has rich porous layer and compact water-resistant layer in microstructure, and is applied for stooping blood and healing wounds in high-permeability seawater environment.

The invention provides a multifunctional electrostatic spinning fiber dressing and a preparation method thereof, and belongs to the technical field of polymer medical materials. The fiber dressing isof a micro-nano structure, the electrostatic spinning method is adopted for spinning polymer materials with grafted functional groups into fiber, then, crosslinking is performed to obtain the fiber dressing, and the polymer materials have the function of stimulating macrophage transition. The invention further provides the preparation method of the multifunctional electrostatic spinning fiber dressing. The electrostatic spinning fiber dressing is obtained by grafting functional groups to polymer materials capable of promoting macrophage transition and then performing electrostatic spinning andcrosslinking, the fiber is soft and easy to fold and can well fit a superficial wound, a deep wound can also be filled with the fiber, and the fiber can achieve the multiple functions of stopping bleeding, resisting oxidation, resisting inflammation, resisting bacteria, promoting healing and reducing scars.

The invention discloses a dragon blood spraying film agent applied to a superficial wound and a preparation technology thereof. The dragon blood spraying film agent is characterized by comprising the following components by weight percent of 1-3% of dragon blood, 2-4% of borneol, 2-6% of polyvinylpyrrolidone, 1-3% of polyethylene glycol 2000, 0.5-2% of methylcellulose, 0.5-2% of ethyecellulose, 0.5-3% of polyving alcohol, 0.01-0.5% of glycerol, 40-70% of ethanol and the balance of distilled water. The preparation technology comprises the steps of dissolving the dragon blood and the borneol drug into solution A by the ethanol with the weight percent; evenly agitating the polyvinylpyrrolidone, the polyethylene glycol 2000, the methylcellulose, the ethyecellulose and the polyving alcohol into the distilled water to swell for 24 hours to prepare solution B, mixing the solution A with the solution B, blending the glycerol, and charging into a pressure spray bottle, and finally obtaining the dragon blood spraying film agent. The spraying film agent sprays the solution containing a drug into fog to be attached to the skin surface to quickly form a film under the effects of bottle pressure and the nozzle pressure. The spray film agent has the effects of stopping bleeding, inhibiting bacterium, healing sore and relieving pain, and is especially suitable for the symptoms such as small-area burns and scalds, scratch, bruise and unhealing score.

The invention relates to a bleeding-stopping and healing-promoting liquid dressing and a preparation method thereof. The liquid dressing is prepared from hydroxypropyl methylcellulose, alginate, modified chitosan, garden burnet root extract, human-like collagen liquid, glycerin, poly hexamethylene monoguanidine, mint oil, etc. The liquid has the functions of bleeding stopping, moisturizing, isolating and bacteria resisting, and is applied to the bleeding-stopping nursing of a superficial wound.

The invention relates to the technical field of medical supplies, specifically to a liquid adhesive bandage and a preparation technology thereof. The liquid adhesive bandage is prepared by free radical polymerization of an acrylate soft monomer, an acrylate hard monomer, a functional monomer, an initiator and a solvent for the preparation of a film-forming main body and with the assistance of a functional auxiliary agent. The liquid adhesive bandage can be applied on a wounded part, and then a layer of soft, non-toxic and non-irritating skin protection film which is not easy to peel off is rapidly formed on the wound surface. The film has good water resistance, air permeability and adhesiveness, prevents outside foreign matter and microorganisms from invading and infecting wounds, and hasthe effect of protecting the wound surface and promoting wound healing. The liquid adhesive bandage is direct and simple to use, is beautiful, comfortable and effective, is suitable for wounds of burn, scald, bruise, scratch, dactylotome cracking, chapped skin, chilblain, etc. and small wounds caused by other trauma, has hemostasis and wound protection effects, and is also suitable for superficialwounds caused after face-lifting, skin ulcer of patients with diabetes or chemotherapy, etc.

The invention belongs to the technical field of a medical apparatus, and specifically relates to a composition used for protecting a skin superficial wound. The main component of the composition is an ethylcellulose substance. The composition belongs to a totally-new waterproof liquid band-aid. In a development experiment of the composition, ethylcellulose is taken as a film forming material, and nitrocellulose is avoided. The composition is free of ethyl acetate and excellent in film forming characteristic and water repellency. The unexpected experimental result shows that the prepared liquid band-aid fundamentally solves the main problem that a traditional liquid band-aid is pungent, irritant, and flammable and combustible.

The invention relates to a preparation method of a traditional Chinese medicine lotion for treating superficial wounds, and belongs to the technical field of traditional Chinese medicine preparation methods. At present, anti-infective medicines such as penicillin, sulfa, etc., are adopted to treat the superficial wounds, transformation reactions are easy to act if the penicillin is applied, and more particularly, if anaphylactic shock is not rescued in time, the life is threatening. The invention has the technical proposal that: roots of Rubus Crataegiflolius Bge, purslane, paris rhizome, fig, Cayratia japonica (Thunb.)Gagnep, sticktight, Radix Berberidis, herba andrographiis, Herba Potentilae, Herba Lobeliae Chinensis, bistort, smilax glabra, aspidium rhizome, Ampelopsis japonica, Chinese white olive, Sabia japonica, futokadsura stem, Caulis Trachelospermi, Fibraurea recisa, Common herons Bill Herb, coralbean bark, Clematis chinensis and glycyrrhiza are got; the above-mentioned medicines are put in water that is 2000ml for 30 minutes, and then are decocted under mild fire; residue is filtrated off by using gauzes to make the traditional Chinese medicine lotion for treating the superficial wounds. The preparation method has the advantage that the manufacture is simple; the made traditional Chinese medicine has small toxic and side effects, and directly reach the lesion part, and has easy absorption; the course of treatment is short, and the cure rate is high.

The invention relates to a multilayered hydrophilic wound dressing for superficial wounds, which is a hydrophilic adhesive film layer formed by applying a composite coating made of medical-grade animal glues, medical-grade plant gums, hemostatic ingredients, bactericide diluent and plant fiber additives on a dressing material contacting a wound contact surface. The outer layer of the wound dressing is a dressing forming film layer for preventing the shrinkage of the wound dressing, the dressing forming film layer can be removed during application, and the wound dressing is uniformly perforated to drain excessive exudates or blood. The inventive wound dressing has improved adhesiveness and can well control the superficial wound infection.

The invention provides a high-adsorbility foam dressing and a preparing method thereof. The high-adsorbility foam dressing is composed of, by mass, 10%-40% of starch, 26%-40% of polyurethane prepolymer, 0.6%-1% of crosslinking agent, 0.6%-20% of chain extender, 1.4%-2% of surfactant, 14%-20% of wetting agent, and 18%-27% of foaming agent. In the high-adsorbility foam dressing and the preparing method thereof, since the starch is adopted as filler, the dressing is made to have higher and quicker water adsorbility capability; meanwhile, the starch can effectively lock solute in seepage liquor, a humid environment is provided for a patient, harmful substances in the seepage liquor like toxin and particles are locked at the same time, a wound self-cleaning effect is achieved, and the probability that a wound gets infected when the dressing is not replaced in time is reduced so that the wound is healed more quickly. The high-adsorbility foam dressing is applicable to partial cortical layer and full cortical layer wounds, superficial wounds, skin pressure ulcer, skin ulcer, leg ulcer, skin bruise, diabetes ulcer, surgical drainage and the like.

The invention discloses a composition as well as a preparation method and application thereof. The composition is prepared from the following raw materials: 5 to 20 parts of beta-glucan, 5 to 30 parts of mannan, 8 to 15 parts of saccharomycetes polypeptide and 1 to 20 parts of sodium hyaluronate. According to the composition prepared by the invention, through the specific synergistic effect of the preparation raw materials, damaged skin is repaired, and oral diseases are treated; and the composition has obvious curative effects on sensitive skin, sunburnt skin, acne, acne skin, diabetic foot, angioneurotic ulcer, superficial wound surface, dental ulcer, dental plaque, periodontitis and the like.

The invention generally relates to the compositions and methods related to the use of adrenergic receptor agonists solutions for the treatment of skin and mucosal superficial wounds. Some of the preferred adrenergic receptor agonists include epinephrine, phenylephrine, norepinephrine, methoxamine, and mixtures thereof. The invention also relates to devices suitable for applying these solutions to the skin or the mucosal area. Methods according to the invention are especially effective to control superficial skin and mucosal bleeding and accelerate healing time.

The invention relates to composite hydrocolloid, a preparation method thereof and a hydrocolloid dressing. The composite hydrocolloid is prepared from the following raw materials: 15 to 90 parts of an effective component, 10 to 30 parts of sodium carboxymethylcellulose and 40 to 100 parts of an adhesive, wherein the effective component comprises tourmaline powder and / or tea tree essential oil wrapped by microcapsules. The far infrared tea tree essential oil application is suitable for later recovery of superficial wounds and burn and scald wounds and inflammation elimination and nursing of acnes, and has a more outstanding effect than common inflammation elimination medicines or dressings.

The invention belongs to the technical field of medical supplies, and particularly relates to a wound nursing ointment and a preparation method thereof. The wound nursing ointment consists of sodium carboxymethyl cellulose (CMC-Na) and an ointment base (polyethylene glycol-20000, carbomer 940). The microbial limit requirements of the wound nursing ointment are as follows: total number of aerobic bacteria shall not exceed 100 per mL; total number of moulds and yeasts shall not exceed 10 per mL; and Staphylococcus aureus and Pseudomonas aeruginosa shall not be detected. Components and proportion(by weight percentage) of the wound nursing ointment are as follows: sodium carboxymethyl cellulose, (CMC-Na), 0.5-50.00%, carbomer 940, 0.1-0.50%, purified water, 0.1-99%, and preservative, appropriate amount. The preparation method comprises the following steps: weighing the raw materials according to the formula proportion (by weight percentage), adding the sodium carboxymethyl cellulose (CMC-Na) and the polyethylene glycol-20000 into a container added with the purified water, and fully dissolving the sodium carboxymethyl cellulose and the polyethylene glycol-20000 to prepare a solution; adding the carbomer 940 into another container added with the purified water, fully swelling the carbomer 940 to prepare an aqueous solution, mixing the solution and aqueous solution, uniformly stirring and subpackaging. The wound nursing ointment is used for nursing care of superficial wounds such as small wounds, abrasions, cuts and the like and surrounding skin.

The invention discloses a medicine for treating burn injury, and a preparation method and a use method thereof. The medicine for treating the burn injury is prepared from the following raw materials in the following usage amounts: 80 to 120g of raw gamboges, 30 to 70g of raw radix aconiti carmichaeli, 400 to 600g of secretio bufonis, 40 to 60g of hydrargyri oxydum rubrum, 100 to 300g of datura flowers, 100 to 200g of common andrographis herb, 5 to 15g of dried body of centipede, 40 to 60g of borneol and 400 to 600g of safflowers. The medicine provided by the invention belongs to the technical field of traditional Chinese medicines, and overcomes various defects of the existing medicine for treating the burn injury; when the medicine is used, the special arrangement of an aseptic ward in the treatment process is not needed; after the medicine is smeared, the superficial wound surface pain can be relieved; in addition, after the healing, a scar is not obvious; no scar can be left on a patient with a skin wound surface or even a small-area wound surface; the wound surface healing speed is high; the pain and the economical burden of the patient are greatly reduced. The medicine can also be used for treating trauma such as knife wounds and skin scratching injury.

The invention discloses a whey protein spray for repairing superficial wounds and a preparation method of the whey protein spray. The whey protein spray is prepared from the following components in percentage by mass: 1.0%-10.0% of whey protein inclusion, 2.0%-3.0% of pentanediol, 0.05%-0.5% of hyaluronic acid, 0.1%-0.5% of dipotassium glycyrrhizinate, 0.2%-2.0% of tetrahydromethylpyrimidine carboxylic acid, 0.05%-1% of madecassoside and the balance of purified water, and the sum of the mass percentages of the components is 100%. The invention also discloses the method. By preparing the repair preparation which is stable, can effectively penetrate through the skin barrier and is rich in protein repair active ingredients, the biological activity of protein can be reserved, and the stability of the protein can also be enhanced. By adding the skin external preparation, the repair of functional organisms is promoted, the repair capacity of the organism is effectively improved, and the repair effect on skin superficial wounds is remarkable.

The invention provides an antibacterial cationic injectable hydrogel and a preparation method thereof. According to the antibacterial cationic injectable hydrogel dressing provided by the invention, hydrogel is obtained by self-crosslinking multi-arm polyethylene glycol, of which the end group is modified by phthalic dialdehyde, as a cross-linking agent with a cationic polymer in a solvent. The antibacterial cationic injectable hydrogel dressing provided by the invention can form gel without participation of catalase, and the obtained antibacterial cationic injectable hydrogel dressing has better gel forming time, does not form gel too slowly or too fast, can be injected for in-situ molding, and can be used for treating deep wounds (hydrogel in the prior art is too fast or too slow in gelling and can only be directly made into gel to be used for superficial wounds); moreover, the mechanical strength of the gel can be improved; and the dressing also has good biocompatibility, degradability and antibacterial property, and good repair promotion capability.

The invention discloses liposome disinfection gel and a preparation method thereof, and relates to the technical fields of antibiosis and disinfection. The lipidosome disinfection gel is composed of the following components in parts by weight: 1.0 to 20.0 parts of a bactericide, 0.5 to 1.5 parts of soybean phospholipid, 0.1 to 1.0 part of carboxylated chitosan, 0.1 to 1.0 part of cholesterol, 1.0to 10.0 parts of glycerol, 5.0 to 15.0 parts of carboxymethyl starch sodium, 2.0 to 10.0 parts of sodium alginate, 0.1 to 1.0 part of amino acid, 0.2 to 1.0 part of vitamin E and 39.5 to 90.0 parts ofpurified water. The bactericide disclosed by the invention is prepared from various different non-irritant substances, the bactericide is encapsulated by a liposome technology, the effect of bactericide is released by virtue of the contact effect of lipidosome; the skin disinfectant is used as a carrier, so that effective components can quickly and accurately reach an acting part, quick sterilization and long-acting bacteriostasis are realized, and the problems that inflammation is easily generated and even scars are formed after the wound is healed when an existing skin disinfectant is usedfor disinfecting the superficial wound and the wound cannot be prevented from being polluted by the outside after disinfection are solved by utilizing a physical film forming principle.

The invention discloses a sodium carboxymethylcellulose liquid dressing and a preparation method thereof, which belong to the technical field of medical supplies. The sodium carboxymethylcellulose liquid dressing is prepared from sodium carboxymethylcellulose (CMC-Na), purified water and a preservative. The microbial limit requirements are as follows: the total number of aerobic bacteria per 1mL does not exceed 100; wherein the total amount of molds and saccharomycetes is not more than 10 per 1mL; staphylococcus aureus and pseudomonas aeruginosa cannot be detected. The sodium carboxymethylcellulose liquid dressing comprises the following components in parts by weight: 0.5-50.00% of sodium carboxymethylcellulose (CMC-Na), a proper amount of purified water, and a proper amount of the preservative. The preparation method comprises the following steps: weighing the raw materials (weight ratio) according to the formula ratio, putting the raw materials sodium carboxymethylcellulose (CMC-Na)and the preservative into a container added with the purified water, fully dissolving to prepare a solution, uniformly stirring the materials, and performing sub-packaging to obtain the product. A protective layer is formed on the surface of a wound surface, so that the physical barrier effect is achieved. The dressing is used for nursing superficial wounds such as small wounds, scratches and incisional wounds and surrounding skin.

The invention provides a liquid dressing and a production method thereof, and belongs to the technical field of medical supplies. The liquid dressing is composed of polyvinylpyrrolidone (PVP), carbomer 940 and purified water. Microbial limit requirements are that the total number of aerobic bacteria is less than or equal to 100 cfu / mL, the total number of molds and yeasts is less than or equal to 100 cfu / mL, and staphylococcus aureus and pseudomonas aeruginosa are not detected. The liquid dressing is prepared from, by weight, 0.5-50.00% of the polyvinylpyrrolidone, 0.1-0.50% of the carbomer 940, 0.1-99% of the purified water and an appropriate quantity of a preservative. The technological method comprises the steps that the raw materials are weighed according to a formula ratio, the raw material polyvinylpyrrolidone and preservative are placed in a container filled with the purified water, so that the polyvinylpyrrolidone and the preservative are fully dissolved to prepare a solution; the carbomer 940 raw material is placed in an another container filled with purified water, so that the carbomer 940 raw material fully swells to prepare a hydrogel solution, and then the solution and the hydrogel solution are mixed, stirred uniformly and subpackaged to form the liquid dressing. A protection layer is formed on the surface of a wound, which plays a physical barrier role. The liquid dressing is used for nursing of small wounds, abrasions, incised wounds and other superficial wound surfaces and surrounding skin.

The present invention belongs to the field of medicines, and in particular relates to a composition for superficial wounds. The composition comprises a mussel soft tissue extract and papain. The composition is suitable for the superficial wounds, especially protection and treatment of bruises, bumps, scratches, frostbite, mosquito bites, dermatitis, eczema, skin ulcer, herpes zoster, surgical incision, laser wounds, superficial II degree burns and the like, can protect the wounds, promotes wound healing, and relieves itching and pains. The composition is mild, non-stimulating, free of toxic and side effects, and free of use dependent.

The invention discloses an application of recombinant human collagen III type in preparation of a superficial wound repair material. The recombinant human III type collagen contains 498 amino acids, the theoretical molecular weight is about 54.5 kd, and the constructed recombinant human III type collagen expression strain can effectively, stably and massively express the recombinant human III type collagen. The recombinant human collagen has good hydrophilicity and stability, the structure of the recombinant human collagen is 100% the same as that of a corresponding part of a natural collagen gene sequence, and immunological rejection is not caused when the recombinant human collagen is applied to a human body. When the recombinant human III type collagen is used as a superficial wound repair material, the scabbing time is advanced by 1-2 days, the wound healing time is obviously shortened, the wound is smooth and smooth, the wound healing quality is improved, no obvious scar exists, and the recombinant human III type collagen is suitable for the fields of skin care products, medical instruments and the like.

The invention discloses a liquid dressing and a preparation method thereof. The liquid dressing is prepared from raw materials, by weight, 55-70 parts of absolute ethyl alcohol, 7-22 parts of polyacrylic resin IV, 5-25 parts of ethyl acetate and 0.1-3 parts of lubricant; the liquid dressing is simple in component, free of irritation to skin, safe to use, short in film-forming time, good in toughness and good in film-forming property, can be directly sprayed on the surface of a superficial wound, has the effects of stopping bleeding, protecting the wound, adhering the epidermis, preventing water and inhibiting bacteria, and can be used for nursing irregular wounds.

The invention relates to an absorptive element that is to be mounted on human or animal skin surfaces in the area of wounds. Said absorptive element is composed of an outer coating (2) that is permeable to liquid substances and an inner layer (1) which is enclosed by the coating (2) and substantially comprises a mixture of an amount of osmotically highly active substances and an amount of osmotically relatively weak or inactive substances, such as cellulose. The inner layer (1) is filled with osmotically active substances in such a way that an osmotic pressure, via which the wound fluid contained in a wound can be removed from the organism that is to be treated, can be applied to the wound with the wound fluids contained therein, thus supporting interstitial normohydration in both the superficial wound region and in the deep tissue by the fact that the body's own fluids are directed into the absorptive element in the direction of flow thereof towards the patient's skin surface and are retained there.

The invention discloses an oral care agent which is used for superficial wound care and applied to field of oral care, and an application method thereof. The oral care agent comprises the following components in percentage by weight: 10%-18% of acid, 6%-17% of a carboxyl compound, 0.6%-1.8% of phenol, 0.2%-0.3% of flavones, 0.7%-2.1% of plant factors and 60.8%-82.5% of purified water, wherein theacid, the carboxyl compound and the phenol are hawthorn seed extracts. The oral care agent can form a protective film on the surface of a wound to play a role of a physical barrier, so that the repairing effect of internal medicines on the wound surface is improved. Meanwhile, the components are simple, most of the components are extracted from plants, the product safety can easily reach the foodgrade, and the applicability to the oral environment is effectively improved. Besides, the application method is simple and rapid, and the operation efficiency is improved. On the one hand, medicine strengthening operation is conducted on local parts through wet compressing, and on the other hand, a spray can guarantee the oral cavity environment, so that the good nursing environment is continuously kept, and the repairing effect is improved.

The invention discloses a liquid dressing applied to care of superficial wounds and surrounding skin as well as an application method of the liquid dressing in the field of medicine. The liquid dressing comprises the following components in percentage by mass: 60%-81.7% of a Crataegus cuneata seed dry-distilled liquid, 10%-18% of acetic acid, 6%-17% of hepanal, 0.6%-1.8% of dimethoxyphenol, 0.8%-1.5% of a peppermint essence and 0.9%-1.7% of aloe. The liquid dressing can be applied to the care operation of superficial wounds and surrounding skin of people such as condyloma acuminatum, common warts, flat warts, filiform warts, plantar warts and herpes, and has a certain therapeutic effect, a user can operate according to instructions, the limitation of the treatment process is avoided, the flexibility of operation and application is improved, meanwhile, the treatment pain of a patient is relieved, and the comfort of the diagnosis and treatment process is enhanced. In addition, the components of the liquid dressing are relatively safe and have a low sensitization rate, secondary damage to affected parts is avoided, the care effect is guaranteed, and meanwhile, the improvement of an immune system and the repair of the skin and mucous membranes are realized, so that the diseases cannot easily recur.

The invention provides a field-reinforced type cross-platform portable vital sign monitoring system. The field-reinforced type cross-platform portable vital sign monitoring system comprises a portableultrasonic FAST diagnostic unit, a non-contact monitoring unit based on biological telemetry and a portable multi-parameter monitoring unit; the portable ultrasonic FAST diagnostic unit comprises a deep wound detection probe and a superficial wound detection probe; the non-contact monitoring unit based on biological telemetry comprises a non-contact heart rate monitoring module, a non-contact respiratory monitoring module, a TOI non-contact blood pressure detection module and an infrared temperature measurement module; and the portable multi-parameter monitoring unit comprises an electrocardio monitoring module, a respiratory monitoring module, a body temperature monitoring module, a blood oxygen saturation monitoring module, a heart rate monitoring module and a non-invasive blood pressure detection module. Through the military reinforcement design, the ability of three-proofing, water resistance, shock resistance, vibration resistance and the like in the military field environment can be achieved, and the rapid diagnosis of the wounded part of the wounded, anatomical structure type, injury type, injury class and injury severity score can be quickly diagnosed, and the wounded requiring urgent treatment can be quickly screened.

The invention discloses an antibacterial adhesive bandage containing zinc oxide nanoparticles and a preparation method thereof, and belongs to the technical field of medical supplies. The prepared adhesive bandage consists of an adhesive backing, a drug layer, a chitosan nonwoven layer and strippable layers. The chitosan nonwoven layer contains nano zinc oxide connected through an immersion method; and medicament containing Chinese herbal medicinal ingredients is attached to the drug layer and includes a field thistle extract, chitosan quaternary ammonium salt, growth factors, amino acid, decavitamin and other ingredients. Thus, the problems that existing adhesive bandages cannot promote wounds to heal can be solved, and the technical effects of promoting the wounds to heal quickly and preventing the wounds from being infected can be realized. The prepared adhesive bandage is simple in manufacturing technology, good in biocompatibility, low in cost, non-irritating to the wounds and safe in product, has no toxic and side effects and can absorb the exudate from the wounds; and the adhesive bandage can be applied to the nursing care of superficial wounds such as small wounds, abrasions and cuts.