Composition for superficial wounds
A composition and wound surface technology, applied in the field of medicine, can solve the problems of inconvenience of movement, tearing or pain of patients, single anti-infection or pain relief, etc., and achieve the effects of no dependence on use, alleviation of itching and pain, and beneficial to healing.
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Embodiment 1
[0054] Embodiment 1: A preparation method of mussel soft tissue extract.
[0055] Shell the mussels, collect 300g of soft tissue, divide it into three parts, add 100ml of the acidic solution in the table below with a content of 0.3%, homogenate for 10 minutes, and centrifuge to obtain the supernatant, which is the mussel soft tissue extract.
[0056] The protein content and pH value in the supernatant were determined, and the protein content was determined by the Coomassie brilliant blue method.
[0057] Table 1
[0058] example acid solution protein content pH value 1 citric acid 2.6mg / ml 4.5 2 Acetic acid 3.5mg / ml 3.2 3 perchloric acid 3.0mg / ml 1.0
Embodiment 2
[0059] Example 2: A composition for superficial wounds.
[0060] The composition for superficial wounds including mussel soft tissue extract and papain is composed of the following components: mussel soft tissue extract dry powder 15mg, papain 20mg, sodium chloride 100mg, acetic acid 5ml, after adding water for injection and fully dissolving Made into a spray for superficial wounds.
[0061] Collect 60 cases of patients with superficial skin injuries, including 30 cases after laser surgery, 20 cases of abrasions, and 10 cases of contusions. They were randomly divided into 3 groups. Control group 1 received 15 mg of mussel soft tissue extract, 100 mg of sodium chloride, 5 ml of acetic acid and Spray prepared from water for injection; control group 2 used papain 20mg, sodium chloride 100mg, acetic acid 5ml and water for injection prepared from spray; treatment group used the spray prepared by Example 2 of the present invention.
[0062] The three groups of sprays were used in t...
Embodiment 3
[0068] Example 3: A composition for superficial wounds
[0069] A composition for superficial wounds comprising mussel soft tissue extract and papain consists of the following components: dry powder of mussel soft tissue extract 13.5 mg, papain 18 mg, methylcellulose 20 mg each, propylene glycol 100 mg glycerin 100 mg, 3 mg of citric acid, appropriate amount of water for injection, dry powder of mussel soft tissue extract and papain are added to the swollen gel matrix to obtain a hydrogel for superficial wounds.
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