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Composition for superficial wounds

A composition and wound surface technology, applied in the field of medicine, can solve the problems of inconvenience of movement, tearing or pain of patients, single anti-infection or pain relief, etc., and achieve the effects of no dependence on use, alleviation of itching and pain, and beneficial to healing.

Inactive Publication Date: 2017-05-31
BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently, externally applied drugs for treating superficial skin injuries, such as silver sulfadiazine, povidone-iodine ointment, Yunnan Baiyao, etc., are single-effect (anti-infection or pain-relieving) preparations, or use gauze dressings and wound dressings to protect the wound and absorb it. Exudate, prevent wound infection, but cause inconvenience to the patient or cause wound tearing or pain when changing dressings

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Embodiment 1: A preparation method of mussel soft tissue extract.

[0055] Shell the mussels, collect 300g of soft tissue, divide it into three parts, add 100ml of the acidic solution in the table below with a content of 0.3%, homogenate for 10 minutes, and centrifuge to obtain the supernatant, which is the mussel soft tissue extract.

[0056] The protein content and pH value in the supernatant were determined, and the protein content was determined by the Coomassie brilliant blue method.

[0057] Table 1

[0058] example acid solution protein content pH value 1 citric acid 2.6mg / ml 4.5 2 Acetic acid 3.5mg / ml 3.2 3 perchloric acid 3.0mg / ml 1.0

Embodiment 2

[0059] Example 2: A composition for superficial wounds.

[0060] The composition for superficial wounds including mussel soft tissue extract and papain is composed of the following components: mussel soft tissue extract dry powder 15mg, papain 20mg, sodium chloride 100mg, acetic acid 5ml, after adding water for injection and fully dissolving Made into a spray for superficial wounds.

[0061] Collect 60 cases of patients with superficial skin injuries, including 30 cases after laser surgery, 20 cases of abrasions, and 10 cases of contusions. They were randomly divided into 3 groups. Control group 1 received 15 mg of mussel soft tissue extract, 100 mg of sodium chloride, 5 ml of acetic acid and Spray prepared from water for injection; control group 2 used papain 20mg, sodium chloride 100mg, acetic acid 5ml and water for injection prepared from spray; treatment group used the spray prepared by Example 2 of the present invention.

[0062] The three groups of sprays were used in t...

Embodiment 3

[0068] Example 3: A composition for superficial wounds

[0069] A composition for superficial wounds comprising mussel soft tissue extract and papain consists of the following components: dry powder of mussel soft tissue extract 13.5 mg, papain 18 mg, methylcellulose 20 mg each, propylene glycol 100 mg glycerin 100 mg, 3 mg of citric acid, appropriate amount of water for injection, dry powder of mussel soft tissue extract and papain are added to the swollen gel matrix to obtain a hydrogel for superficial wounds.

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PUM

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Abstract

The present invention belongs to the field of medicines, and in particular relates to a composition for superficial wounds. The composition comprises a mussel soft tissue extract and papain. The composition is suitable for the superficial wounds, especially protection and treatment of bruises, bumps, scratches, frostbite, mosquito bites, dermatitis, eczema, skin ulcer, herpes zoster, surgical incision, laser wounds, superficial II degree burns and the like, can protect the wounds, promotes wound healing, and relieves itching and pains. The composition is mild, non-stimulating, free of toxic and side effects, and free of use dependent.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a composition for superficial wounds. Background technique [0002] The skin is an important organ of the human body. It plays a role in controlling body temperature, preventing infection, immunity and sensing. Superficial skin injuries such as abrasions, bruises, scratches, frostbite, insect bites, dermatitis, eczema, skin ulcers, herpes zoster, surgical incisions, laser wounds, superficial second-degree burns, etc., usually cause bleeding, pain, Problems such as difficult healing and infection. In superficial skin injuries, because the nerve endings are exposed to stimulation, the wound will produce severe pain, and it is easy to cause bacterial infection, loss of body fluid and complications. [0003] Currently, externally applied drugs for treating superficial skin injuries, such as silver sulfadiazine, povidone-iodine ointment, Yunnan Baiyao, etc., are single-effect (anti-infection...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61P17/02A61K35/618
CPCA61K38/4873A61K35/618C12Y304/22002
Inventor 王小磊
Owner BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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