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Composition used for protecting skin superficial wound

A kind of composition and superficial technology, applied in medical science, bandages, etc., can solve the problems of strong irritation, pungent smell, affecting acceptance, etc., achieve good film-forming properties and waterproof performance, and solve the effect of pungent smell

Inactive Publication Date: 2017-11-07
沈阳恒源药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Liquid bandages are applied on wounds in liquid form. At present, related products on the domestic market have basically solved the problem that traditional bandages cannot stick firmly, but the common problems are that they are irritating, have a certain odor, and are waterproof Poor, needs further improvement
Most domestic products use polyvinyl alcohol as the film-forming material, and organic solvents are not used as the main volatile solvent. The main problem is that polyvinyl alcohol has a certain water solubility, so the waterproof performance is poor and cannot meet the waterproof requirements. [References 1 Wang Tianyu, Zhang Meijing, Fang Shengnan, etc. Research progress of waterproof liquid band-aid. Chinese Journal of New Drugs. 2016,25(4):433-438, 2 Liu Haixia, Zhang Aijun, Zhang Lin. Research progress of liquid band-aid. Chinese Medical Science, 2016, 6(4): 28-31]
[0005] Among foreign products, taking NEW SKIN Liquid Band-Aid and Coloskin Liquid Band-Aid with good reputation as examples, both use low-nitrogen nitrocellulose, also known as nitrocellulose, as a film-forming material with good film-forming properties. Features and waterproof performance, it is the best among liquid bandages; its main problems are: 1. These products generally contain organic solvents such as ethyl acetate and ethanol with high concentrations, so they not only smell pungent but also use 2. Low-nitrogen nitrocellulose is a flammable and explosive raw material, which poses a great safety hazard in production. The film formed on the wound surface of the user is also very flammable, and if it is close to the fire source, it is easy to cause safety problems for burn patients [Reference 1 Wang Tianyu, Zhang Meijing, Fang Shengnan, etc. Research Progress of Waterproof Liquid Band-Aids. China New Drugs Journal. 2016, 25(4):433-438, 2 Liu Haixia, Zhang Aijun, Zhang Lin. Research progress of liquid band-aid. Chinese Medical Science, 2016, 6(4): 28-31]

Method used

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  • Composition used for protecting skin superficial wound
  • Composition used for protecting skin superficial wound
  • Composition used for protecting skin superficial wound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Sources of experimental materials: ethyl cellulose (pharmaceutical grade), Colorcon Coating Technology Co., Ltd.; castor oil (pharmaceutical grade), Hunan Erkang Pharmaceutical Co., Ltd.; benzyl alcohol (pharmaceutical grade), Hunan Erkang Pharmaceutical Co., Ltd.; Isooctane (analytical pure), Sinopharm Chemical Reagent Co., Ltd.; Isopropanol (analytical pure), Tianjin Kemiou Chemical Reagent Co., Ltd.; Ethanol (analytical pure), Tianjin Kemiou Chemical Reagents Ltd. Other reagents were commercially available analytically pure.

Embodiment 1

[0024] 1. formula:

[0025]

[0026] 2. Preparation process:

[0027] (1) At room temperature, weigh the ethyl cellulose of the recipe amount and add it to the batching container;

[0028] (2) Under stirring at room temperature, add the formula amount of isooctane, isopropanol and ethanol in sequence;

[0029] (3) Under stirring at room temperature, add the formula amount of benzyl alcohol and castor oil;

[0030] (4) Continue to stir until a viscous solution is formed;

[0031] (5) Packing.

Embodiment 2

[0033] 1. Recipe

[0034]

[0035] 2. Preparation process:

[0036] (1) At room temperature, weigh the ethyl cellulose of the recipe amount and add it to the batching container;

[0037] (2) Under stirring at room temperature, add the formula amount of isooctane, isopropanol and ethanol in sequence;

[0038] (3) Under stirring at room temperature, add the formula amount of benzyl alcohol and castor oil;

[0039] (4) Continue to stir until a viscous solution is formed;

[0040] (5) Packing.

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Abstract

The invention belongs to the technical field of a medical apparatus, and specifically relates to a composition used for protecting a skin superficial wound. The main component of the composition is an ethylcellulose substance. The composition belongs to a totally-new waterproof liquid band-aid. In a development experiment of the composition, ethylcellulose is taken as a film forming material, and nitrocellulose is avoided. The composition is free of ethyl acetate and excellent in film forming characteristic and water repellency. The unexpected experimental result shows that the prepared liquid band-aid fundamentally solves the main problem that a traditional liquid band-aid is pungent, irritant, and flammable and combustible.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a composition for protecting superficial skin wounds. Background technique [0002] In our daily life, it is always inevitable to encounter superficial skin injuries, such as daily skin scratches, abrasions, punctures, abrasions, chaps, barbs and other superficial skin traumas. Although such trauma does not require professional treatment in hospital institutions, it will affect daily life behavior if it is not protected. At the same time, during the wound healing process, the use of wound dressings is beneficial to protect the wound from external aggressions, including physical damage. Contact irritation and reinfection of microorganisms such as bacteria. [0003] What generally use in the family at present is traditional Band-Aid. Traditional band-aids can protect wounds, prevent infection, and promote healing after use; but the adhesive plaster used has po...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0052C08L1/28
Inventor 丁平田郭恒
Owner 沈阳恒源药业有限公司
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