88 results about "Ecthyma" patented technology

The invention provides a pathogen inspection reagent, and concretely discloses a primer probe combination and a kit for combined inspection of 15 kinds of respiratory tract infection pathogens. By aiming at specific target sequences of the gene sequence conserved region of klebsiella pneumoniae, haemophilus influenzae, streptococcus pyogenes, staphylococcus aureus, escherichia coli, chlamydia pneumoniae, mycobacterium tuberculosis, stenotrophomonas maltophilia, baumanii, mycoplasma pneumoniae, enterococcus faecalis, ligionella pneumohpillia, streptococcus pneumoniae, bacillus pyocyaneus and mycobacterium abscessus, primers and probes which do not have mutual crossed reaction are designed, so that the problem that detection probes of different pathogens can easily generate mutual influenceor interference is solved; the combination and matching of different primers and probes are ensured; the goal of simultaneously performing efficient specific inspection at the same temperature can also be achieved.

A Chinese medicine in the form of ointment for treating ecthyma, bed sore, burn and scald is prepared from 4 Chinese-medicinal materials including Dragon's blood, frankincense, coptis root, etc.

The invention discloses a Chinese traditional medicine plaster, in particular a Chinese traditional medicine plaster for treating ecthyma and a preparation method thereof. The Chinese traditional medicine plaster for treating ecthyma is characterized by being prepared from the following components: calomel, red lead, verdigris, fried mastic, fried myrrh, dragon's blood, red sage root, musk, pangolin, crinis ustus, bee wax and sesame oil. The Chinese traditional medicine plaster of the invention is specially used for treating ecthyma; various medicines are properly matched, and synergistic action or resistant action among the medicines is used for improving the treatment effect, adapting to the treatment requirements on complex diseases and reducing the adverse reaction; and the Chinese traditional medicine plaster of the invention can be used for treating both principal and secondary aspects of diseases, has no need of firing and heating, has very strong penetration and absorption capacities, can directly act on affected parts, has fast and lasting treatment effect, can be externally used conveniently, is safe and reliable, has no side effect, and has better effect on treating ecthyma. The Chinese traditional medicine plaster is used for totally treating 750 cases, and the total effective rate reaches 95%.

The invention relates to a lignin compound that could prevent yellow staphylococcal bacteria and B type hemolytic streptococcus, and the medicine combination of the compound. The invention of lignin Morgan dandehon herb acid A and Rufescidride has obviously effect restraining yellow staphylococcal and B type hemolytic streptococcus. It is also respected to prevent the diseases caused by them, like boil, blain, toxicity epidermis necrolysis, pneumonia, etc.

The invention relates to a slow-releasing agent of antibiotics containing aminoglycoside, comprising slow-releasing micro-sphere containing slow-releasing findings and aminoglycoside antibiotics, and special dissolvent containing suspending adjuvant agent such as sodium carboxymethyl cellulose with the adhesive degree being 100cp-3000cp (at 20-30 Deg. C). The slow-releasing findings comprises EVAc, polyphenyl, PLA, PLGA, decanedioic acid copolymer, albumen glue and gelatin; the slow-releasing micro-sphere can be produced to slow-releasing implanting agent and unguent agent. When the slow-releasing implanting agent and injection is placed or injected into bacteria, the medicine can be released slowly for more than 5-30 days, and toxicity is dramatically reduced at the same time when effective medicine concentration is got and maintained. The said slow-releasing agent is specially effective for chronic medullitis, bedsore, intractable ulcer on skin, diabetes femoral head necrosis and other abscessus, which are caused by Staphylococcus, Streptococcus, Streptococcus, acne Propionibacteriaceae, Enterobacter, Enterobacter, gonotoxin or parameningococcus.

Disclosed is a Chinese medicament for treating ecthyma and its preparing process, which is prepared from the following medicinal materials (by weight portion): zanthoxylum piperitum 10-15, bunge corydalis herb 10-15, Chinese ephedra 10-15, banksia rose 15-20, native copper 15-20, Chinese gall 5-10, cantharidin 0.5-1, allume 5-10, orpiment 5-10, mercurous chloride 0.5-1 and red precipitate 0.5-1.

The invention discloses a goatpox, sheeppox and contagious ecthyma triple cell attenuated vaccine and a preparation method and application thereof. The effective components of the vaccine are separated by an inventor automatically, and after attenuation culture is conducted, goatpox virus, sheeppox virus and Orf virus cell passage attenuated viruses or passage viruses thereof are obtained, wherein a goatpox virus is a Goatpox Virus HN-XY2010F43 strain, a sheeppox virus is a Sheeppox Virus GS-WW 2010 F44 strain, and an Orf virus is an Orf Virus HB-TS09F65 strain. It is shown through attacking protection test results that the prepared goatpox, sheeppox and contagious ecthyma triple cell attenuated vaccine is safe and capable of producing an effective immune protection force, and important practical significance in developing safe and efficient goatpox, sheeppox and contagious ecthyma triple cell attenuated vaccine and preventing and controlling goatpoxes and ecthyma is achieved.

The invention provides a bovine testicle cell line and an establishment method thereof. The establishment method comprises the following main steps: (1) primary culture, namely collecting a bovine testicle of a newborn calf in a sterile manner, cleaning adhesive tissues, separating by virtue of a trypsinization method so as to obtain bovine testicle cells with high vitality, culturing the separated bovine testicle cells with high vitality in a DMEM (Dulbecco modified eagle medium), and culturing at 37 DEG C under the condition of 5% CO2 to obtain primary bovine testicle cells; (2) transfection and screening, namely extracting and purifying eukaryotic expression plasmids pCI-neo-hTERT containing hTERT genes, leading the extracted and purified eukaryotic expression plasmids pCI-neo-hTERT to the primarily cultured bovine testicle cells in the step (1) to perform transfection by adopting a lipidosome transfection method; (3) screening and enlarged culture. The bovine testicle cells provided by the invention are easy in culture and relatively fast in growth speed, can be stably inherited, are high in motility rate and purity, and can be well preserved; the method provided by the invention is simple and convenient in operation and convenient in popularization and application. The cell line can be used for producing hog cholera vaccines, sheep poxes, ecthyma vaccines and the like.

A Chinese medicine in the form of plaster for treating ecthyma is prepared from 9 Chinese-medicinal materials including rosin, calomelas, almond, myrrh, etc through proportionally mixing, mashing, immersing in sesame oil, decocting while stirring, filtering and decocting.

The invention discloses a flavonoid glycoside and medical salt and application to prevent Micrococcus pyogenes and beta hemolytic streptococcus, which is characterized by the following: preventing pustule, toxic epidermal decay, acute myocarditis, cystitis, cervicitis and tumour of neutral nerve system; fitting for treating prostatitis, pneumococcus, medullitis and knuckle disease.

The invention relates to a release injection which contains cefradine, wherein it is formed by release micro ball and dissolvent; the release micro ball contains release findings and penicillin antibiotic; the dissolvent is the special one contains sodium carboxymethyl cellulose as suspension agent; the viscosity is 100cp-3000cp (20Deg. C-30Deg. C); the release agent is selected from EVAc, polyphenyl, PLA, PLGA, sebacic acid polymer, protein pastern, and dope; the release micro ball can be made into release implant agent; the release implant agent and release injection is laid on bacteria stove or injected, to release the medicine for 5-30 days, to keep the effective medicine density and reduce the whole toxicity. The invention can be used to cure the infection caused by staphylococcus, streptococcus, etc.

A powder injection for treating respiratory tract infection, tonsillitis, pneumonia, cholecystitis, appendicitis, cancers, etc is prepared from oldenlandia through extracting, refining, mixing it with cosolvent and excipient, and freeze drying.

A powder injection for treating pneumonia, appendicitis, cellular tissue inflammation, bacterial dysentery, tumors, etc is prepared from glabrous sarcandra herb through extracting, mixing it with cosolvent and excipient and freeze drying.

The invention relates to a slow-releasing agent or rslow-releasing implanting agent containing antibiotics. The injection comprises slow-releasing micro-sphere and dissolvent. The slow-releasing micro-sphere contains slow-releasing findings and antibiotics, and dissolvent contains suspending adjuvant agent such as sodium carboxymethyl cellulose with the adhesive degree being 100cp-3000cp (at 20-30 Deg. C). The slow-releasing findings comprises EVAc, polyphenyl, PLA, PLGA, decanedioic acid copolymer, albumen glue and gelatin; the slow-releasing implanting agent is prepared with slow-releasing micro-sphere or through other methods. When said antibiotics is placed or injected into bacteria, the medicine can be released slowly for more than 10 days, and toxicity is dramatically reduced at the same time when effective medicine concentration is got and maintained. The said slow-releasing agent is specially effective for chronic medullitis, bedsore, intractable ulcer on skin, diabetes femoral head necrosis and other abscessus, which are caused by Staphylococcus, Streptococcus, Streptococcus, acne Propionibacteriaceae, Enterobacter, Enterobacter, gonotoxin or parameningococcus.

The invention belongs to the field of Chinese medicinal preparations, in particular to the field of pastes. A Chinese medicinal paste having the effect of activating blood circulation and reducing swelling comprises the following medicinal components by mass: 30 to 60g of medlar, 20 to 40g of mongolian dandelion herb, 20 to 40g of honeysuckle flower, 20 to 40g of feverfew, 20 to 40g of semiaquilegia root and 1,000 to 1,500g of vaseline. The Chinese medicinal paste has the effects of clearing away heat and releasing toxin, activating blood circulation and reducing swelling, and eliminating pusand promoting granulation, is suitable for treating furuncle, carbuncle, furuncul osis, empyrosis, chimatlon, bedsore and ecthyma, and has the total effective rate of 89.2 percent, and no toxic or side effect.

The invention discloses a method for preventing and treating sheep flock ecthyma. The method includes the steps of firstly, preparing liquid medicine; secondly, preparing ointment; thirdly, preparing edible medicine; fourthly, treating diseased sheep; fifthly, performing sheep flock prevention. The method has the advantages that the medicine is made of Chinese herbal medicine and has no side effect on the growth of sheep flock, no medicine remains in sheep bodies, and pollution to the living environment of the sheep is avoided; oral taking and external application are used to achieve evident curative effect, the sheep with serious ecthyma can be cured by using the method for two days, relapse probability is lowered greatly, and the prepared edible medicine has evident special effect on preventing the ecthyma.

The invention relates to effective emulsified paste for treating skin wound inflammation and a manufacturing method thereof. The effective emulsified paste for treating skin wound inflammation mainly comprises the following components in part by weight: 500 parts of Vaseline, 5 parts of camellia oil, 30 parts of powdered calamine, 0.3 part of vitamin A, 0.5 part of amoxicillin, and 2.4 parts of penicillin sodium in 4 million units. The effective emulsified paste is suitable for treating skin wounds of human body, skin diseases, water and fire burns, wound infection, herpes, balanitis, external candial infection, tinea cruris, pruritus vulvae, vaginal canker, anabrosis, nameless sores or boils, perianal abscess, ulcer, crystalli, impetigo, eczema, rhinitis, beriberi, dermatitis, itch, freckle removing and acne removing, has the characteristics of low production cost and obvious action effect, can effectively diminish swelling, relieve pain, eliminate necrotic tissues, promote granulation, promote growth of muscle cells of human body, accelerate the growth of skin cells, eliminate toxin, beautify skin, clear heat, promote diuresis, sterilize and relieve itching.

The invention relates to a preparation method of traditional Chinese medicine for treating qi-deficiency-type ecthyma, which belongs to the technical field of traditional Chinese medicine preparation method. The existing way for treating the qi-deficiency-type ecthyma generally adopts antibiotics and sulfonamides, if penicillin is adopted, a skin test is needed before utilizing the penicillin, the penicillin is forbidden to use for positive result in the skin test, delayed anaphylactic shock can occur during the continuous application process of the penicillin for very few people to threaten the life of people when not being rescued in time. The technical scheme provided by the invention is that: Chinese dates, yams, black-bone chicken, wild cabbage, dried longan pulp, rhizoma atractylodis macrocephalae, American ginseng, lotus seeds, codonopsis pilosula, sharpleaf galangal fruits, astragalus mongholicus, rhizoma polygonati, polished round-grained rice, dry gingers, prepared rehmannia root, polygonum multiflorum, Chinese angelica, radix paeoniae alba, longan pulp, wheat, pigeonpea and liquorice are placed in the water to be soaked and to be decocted with slow fire, and the decocted liquid medicine is the traditional Chinese medicine for treating the qi-deficiency-type ecthyma. The preparation method has the advantages that the prepared traditional Chinese medicine is simple to produce, has small toxic and side effects, short course of treatment and high curative rate. Moreover, adverse reaction caused by Western medicine can also be avoided.

The invention relates to a preparation method for a traditional Chinese medicine lotion for treating heart blood stasis type ecthyma and belongs to the technical field of the preparation method for the traditional Chinese medicine. At present, antibiotics and sulfonamides which are used for treating the heart blood stasis type ecthyma have the defect of serious toxic and side effects. According to the technical scheme provided by the invention, the preparation method comprises the following steps: taking hematoxylon, spina gleditsiae, myrrh, caulis spatholobi, frankincense, herba lycopi, selaginella tamariscina, acronychia pedunculata, rhizoma polygoni paleacei, semen leonuri, euonymus alatus, carcuma longa, peach kernel, Chinese trumpet creeper, galium aparine, dysosma versipellis, radices stellariae dichotomae, creeping oxalis, sandalwood, veronicastrum herb, daghestan sweetclover herb, coffee senna, common alstonia bark, lophatherum gracile, butterflybush flower, mung bean, dandelion, red-spotted stonecrop, perny false fairybells rhizome, shrubby breynia, small-leaved desmodium, wintercherry, Chinese twinleaf rhizome, uniflower swisscentaury root, olive, small-leaved lemmaphyllum, creeping rostellularia herb, gamboge, China rose and liquorice; soaking the 51 medicines in water; decocting by utilizing slow fire; and obtaining the decocted liquid medicine, namely, the traditional Chinese medicine lotion for treating the heart blood stasis type ecthyma. The preparation method has the advantages that the prepared traditional Chinese medicine is small in toxic and side effects, the course of treatment is short and the cure rate is high.

A traditional Chinese medicine lotion preparation method for curing stomach-yin deficiency ecthyma belongs to the technical field of traditional Chinese medicine preparation methods. At present, antibiotics and sulfonamides are generally adopted for curing stomach-yin deficiency ecthyma. If penicillin is adopted for treatment, a skin test has to be done before the treatment, and if tested positive, patients are not allowed to use penicillin. The technical scheme of the method is that 25 herbs of black-bone chicken, mrlberrt fruit, radix scrophulariae, asparagus cochinchinensis, dendrobe, barbary wolfberry fruit, fructus ligustri lucidi, tortoise plastron, turtle shell, semen sesami nigrum, black soybean, Chinese yam, cabbage, arillus longan, rhizoma Atractylodis Macrocephalae, American ginseng, lotus seeds, codonopsis pilosula, fructus alpiniae oxyphyllae, astragalus mongholicus, rhizoma polygonati, polished round-grained rice, rhizoma zingiberis, dried rehmannia and liquorice are putin water to be soaked and then decocted in slow fire, the decocted liquid medicine is the traditional Chinese medicine lotion for curing stomach-yin deficiency ecthyma. The traditional Chinese medicine lotion preparation method for curing stomach-yin deficiency ecthyma has the advantages of being simple in preparation, small in toxic and side effects, short in course of treatment, high in cure rate and capable of avoiding side effects caused by Western medicine.

The invention discloses a preparation method of Chinese lotion for treating traumatic type ecthyma, and belongs to the technical field of preparation methods for traditional Chinese medicines. At present, the traumatic type ecthyma is generally treated by using antibiotics and sulfonamides such as kanamycin which have toxicity to both auditory nerve and kidney; the influence of the antibiotics appears as tinnitus and dysacusis; and the influence of the sulfonamides appears as proteinuria, cylindruria and the like. According to the technical scheme provided by the invention, the preparation method comprises the following steps of: adding 27 medicines, i.e., fruit of princesplume ladysthumb, humifuse euphorbia herb, corydalis tuber, native copper, anomalous wormwood, huechys sanguinea de geer, azalea, sappan wood, spina gleditsiae, myrrh, leatherleaf milletia, frankincense, herba lycopi, selaginella, securinega suffruticosa, scandent schefflera stem and leaf, alangium chinense harms, sabia japonica, pepper stem, Chinese starjasmine stem, herba aristolochiae, geranium carolinianum, safflower, root of red-rooted salvia, tree peony bark, peach kernel and liquoric root, in water to soak; and decocting with slow fire to obtain the lotion, i.e., the Chinese lotion for treating the traumatic type ecthyma. The preparation method has the advantages of low toxic or side effect of the prepared traditional Chinese medicine, short period of treatment, high cure rate and capability of avoiding adverse effects produced by application of western medicines.

The invention discloses a preparation method and applications of gastric floating tablets containing ornidazole, belonging to a novel technical field of medicament and relating to a novel medicament form of ornidazole. 1. The gastric floating tablets are used to treat a plurality of diseases caused by bacteroides fragilis, bacteroides distasonis, bacteroides oval window, etc.; (2) oral cavity infections: pericoronitis, periapical periodontitis, pericoronitis, acute ulcerouse gingivitis etc.; (3) gynae infections: endometritis, myometritis, oviduct or ovarian abscess, pelvic cavity soft tissue infection, haemophilis vaginitis etc.; (4) surgical infections: wound infection, abscess of epidermis, bedsore ulcerouse infection, cellulites, gas gangrene etc.; (5) brain infections: meningitis, brain abscess; (6) septicaemia and severe general infections etc. 2. The gastric floating tablets are used to prevent infections before an operation and treat anaerobic infections after an operation. 3. The gastric floating tablets are used to treat urogenital canal trichomonas and giardia lamblia infections, such as trichomoniasis etc. 4. The gastric floating tablets are used to treat alimentary system amebiasis, such as amebic dysentery, amoebic liver abscess etc. The new medicament form is characterized in that the surface thereof is hydrated into gel after contacting with gastric juice at body temperature so as to cause volume expansion because the gastric floating tablets contain a plurality of hydrophilic macromolecule materials. Weight of the tablets is less than floating force of the gastric juice, so the tablets float on the gastric juice so as to prolong time in a stomach.

The invention provides novel lipopeptides Lin-Lf4NH2 and Lin-Lf5NH2 and application thereof. The lipopeptides Lin-Lf4NH 2 / Lin-Lf 5NH2 are obtained by coupling linoleic acid to the N end of an antibacterial peptide LfcinB4 / LfcinB5 and performing amidation modification on the C end of the antibacterial peptide LfcinB4 / LfcinB 5. Experiments show that the lipopeptides Lin-Lf4NH2 and Lin-Lf5NH2 havea good inhibiting effect on gram-positive bacteria and gram-negative bacteria, have a smaller MIC (minimal inhibitory concentration) value and good thermal stability than a parent peptide, can remarkably reduce the skin bacteria carrying amount and relieve skin tissue injury in a mouse skin abscess model test, have a better treatment effect than Lf4NH2 and Lf5NH2, are small-molecule lipopeptideswith high application value, can be used for preparing novel antibacterial and anti-infection medicines and the like, and have a wide application prospect.

Oral pharmaceutical compositions comprising dry extract of Euphorbia prostrata from about 0.1% to about 99% by weight wherein the effective average particle size of the dry extract of Euphorbia prostrata is not more than about 500 microns with pharmaceutically acceptable excipient(s) and process(s) for the preparation of such compositions useful for the treatment of anorectal disease and colonic diseases such as hemorrhoids, fissures, cracks, fistulas, abscesses, inflammatory bowel disease and the like are provided. Further, the pharmaceutical compositions of the present invention provides for the administration of a therapeutically and / or prophylactically effective amount of the Euphorbia prostrata wherein the compositions possess properties to control inflammation, prevent capillary bleeding and fragility in mammalians, particularly human beings. Furthermore, the compositions preferably provides a release of not less than about 50% of the dry extract of Euphorbia prostrata in first 15 minutes and not less than about 80% of dry extract of Euphorbia prostrata after total dissolution study of about 60 minutes when tested in accordance with the dissolution method described herein employing physiological pH range of about 2 to about 7.5 optionally with surfactant(s). Preferably the compositions of the present invention are in the form of tablets, minitablets, powders, capsules, pellets, granules, beads, compacts and the like. The present invention also provides and prophylactic and / or therapeutic methods of using such compositions for the treatment of anorectal diseases including hemorrhoids and colonic diseases.

The invention discloses an anti-tuberculosis drug and a production method thereof. The anti-tuberculosis drug is mainly prepared from 3-15 parts of rhubarb, 9-15 parts of radix paeoniae alba, 6-15 parts of bletilla striata and 0.1-0.3 part of Semen Crotonis Pulveratum, and is made into pills. The Semen Crotonis Pulveratum is a mixture of croton seed powder and starch. The drug is completely made of Chinese herbal medicines, has the advantages of tuberculosis resistance and sterilization, pus expelling and tissue regeneration promotion, swelling and pain relieving, nerve repairing, promotion of tuberculosis focus absorption and repair, and strengthening of body immune function, etc., is mainly applicable to bone and joint tuberculosis complicated with abscess sinus, spinal tuberculosis complicated with pulmonary tuberculosis, lymphoid tuberculosis, tuberculous pleuritis, intestinal tuberculosis and renal tuberculosis, etc., also has no pain and risk of surgical trauma, and especially has the advantages of small toxic and side effect and adverse reaction, quick effect, short course of treatment and low price, etc.

The present invention relates to a Chinese medicine solution for curing hemorrhoid complicated by anal fistula-Erfan solution, and its composition contains chalcanthite 5-10g, calcined alum 20-25 g, sal ammoniac 35-50g, niter 35-50 g and cane sugar 10-15g. It possesses extensive application range, can be used for curing various-stage internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, anal fistula, splitting of the anus, proctoptosis, perianal abscess, proctopolypus, hypertrophy of anal papilla and papilloma of anus and others, and can obtain good therapeutic effect. It has no any adverse reaction and has no any toxic side-effects.

The invention discloses an external tissue regeneration promoting ointment. The external tissue regeneration promoting ointment is prepared from the following raw materials in parts by weight: 8-22 parts of radix angelicae sinensis, 15-25 parts of resina draconis, 12-25 parts of radix arnebiae seu lithospermi, 20-35 parts of frankincense and myrrh, and 18-30 parts of white wax, wherein radix angelicae sinensis has the efficacies of replenishing blood and promoting blood circulation, regulating menstruation and relieving pain, promoting blood circulation to remove blood stasis, warming and activating meridian, relieving pain and relieving spasm, and enhancing immunity; resina draconis has the efficacies of promoting blood circulation and relieving pain, dispersing blood stasis and stoppingbleeding, promoting tissue regeneration and healing sore, inhibiting bacteria and the like; radix arnebiae seu lithospermi has the efficacies of removing toxicity and removing freckles, clearing heatand eliminating swelling, treating scald, inhibiting bacteria and the like; frankincense has the efficacies of promoting blood circulation and promoting Qi circulation, relieving pain, eliminating swelling and promoting tissue regeneration; and the external tissue regeneration promoting ointment is suitable for traumatic injury, arthralgia and myalgia, ulcer and persistent ulceration, or abscess and ulceration and non-healing, traumatic hemorrhage, burn and scald and the like.

A topical composition is prepared using macerated leaves of St. Andrew's Cross (hypericum hypericoides). An aqueous extract of the leaves is mixed with ethanol to form a spray or to saturate a wet wipe and administer to a mammal skin for treatment a variety of skin conditions, including eczema, psoriasis, rosacea, cellulitis, contact dermatitis, seborrhoeic dermatitis, nummular dermatitis, dandruff, stasis dermatitis, perioral dermatitis, dermatitis herpetiformis, ecthyma, impetigo, shingles, urticaria, tinea pedis, tinea manuum, tinea cruris, sunburn, insect bites and stings, jellyfish stings, granuloma annulare, bullous pemphigoid, lichen planus, bed sore, inflammations caused by waterborne vectors, diaper rash, heat rash, pityriasis rosea, jungle rot, scleroderma, skin rashes and photo-aging.