132 results about "Digestive disorder" patented technology

Provided are electrokinetically-altered fluids (e.g., gas-enriched (e.g., oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide, upon contact with a cell, modulation of at least one of cellular membrane potential and cellular membrane conductivity, and therapeutic compositions and methods for using same in treating digestive disorders or at least one symptom thereof. The electrokinetically-altered fluid compositions and methods include electrokinetically-altered ioinic aqueous fluids optionally in combination with other therapeutic agents. Particular aspects provide for regulating or modulating intracellular signal transduction associated with said digestive disorders by modulation of at least one of cellular membranes, membrane potential, membrane proteins such as membrane receptors, including but not limited to G-Protein Coupled Receptors (GPCR), and intercellular junctions (e.g., tight junctions, gap junctions, zona adherins and desmasomes). Other embodiments include particular routes of administration or formulations for the electrokinetically-altered fluids and therapeutic compositions.

The instant invention relates to the use of compounds that are effective as selective opiate receptor modulators for the manufacture of pharmaceuticals for the diagnosis and / or the treatment of disorders, said disorders being selected from eating disorders and digestive disorders, especially psychogenic eating disorders, for the manufacture of a pharmaceutical effective for modulating, the gastrointestinal tonus, and to pharmaceutical composition, comprising one or more of said modulator compounds and one or more compounds that are effective as appetite depressant.

The invention relates to a biological fermentation composition with an anti-cancer effect. The biological fermentation composition is prepared by using a method comprising the following steps: a, preparing a culture medium mixed solution; b, sterilizing; c, cooling; d, inoculating to obtain a fermentation solution; and e, standing to obtain the biological fermentation composition with the anti-cancer effect. The composition disclosed by the invention can be used for improving the in-vivo micro-ecological environment, balancing and regulating effective microbial communities in intestinal canals, repairing damaged cells, replenishing various in-vivo active bio-enzymes, amino acids, nucleic acids, trace elements and the like, improving the immunity of a human body, preventing diseases, effectively inhibiting cancer cells and stopping the dispersion and development of the cancer cells. Meanwhile, the biological fermentation composition can be used for improving an acidic physique to be a weak alkaline physique, is particularly suitable for the cancer crowd, the crowd with hypertension, hyperlipidemia and hyperglycemia and the fat crowd, can be prepared into various dosage forms such as pills, paste, aqueous solutions and the like, and has favorable supportive therapeutic effects on cancer, diabetes, digestive system diseases and the like.

There is provided methods, kits, combinations, and compositions comprising a Aspergillus oryzae protease enzyme, a Bacillus subtilis protease enzyme, and a Aspergillus niger lipase enzyme for treating a digestive disorder in a subject in need thereof. The methods, kits, combinations, and compositions may also be used along with an agent (or combination of agents) for raising the gastric pH, a digestive enzyme useful in enhancing digestive activity, a dietary supplement, or a pharmaceutical agent.

The invention discloses an application of morelberry in the preparation of medicines for curing digestive system diseases, the product and the preparation method, wherein, the medicine adopts moreberry as material; the moreberry can be superfinely pulverized directly or extracted with water or ethanol to obtain the extraction, so as to prepare into various medicament forms based on traditional preparation technology. The application overcomes the disadvantages of the prior art and provides the application of morelberry in the preparation of medicines for curing digestive system diseases. The medicine has the advantages of simple preparation method, low cost, obvious treatment effect, less adverse reaction, effective treatment of various digestive system diseases and no relapse after recovery.

This invention provides a process for the preparation of compositions enriched in total phenols from a crude plant extract. The process includes a novel column purification step using a brominated polystyrene resin. This invention also includes compositions enriched in total phenols. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols and having HPLC chromatograms substantially as set forth in FIGS. 10-13. This invention encompasses methods of using the total phenol-enriched compositions for treating warm-blooded animals, including humans, infected with paramyxovaridae such as respiratory syncytial virus, orthomyoxovaridae such as influenza A, B, and C, parainfluenza, Herpes viruses such as HSV-1 and HSV-2, and Flaviviruses such as West Nile Virus, and for treating inflammation such as caused by arthritis, stress and digestive disease.

The present invention relates to the compound represented by formula (I):(wherein, all the symbols has the same meanings as that of the specification), a salt thereof, a solvate thereof or a prodrug thereof.Since the compound of the present invention has an anti stress action, it is useful for preventive and / or therapeutic agent for a disease caused by stress, especially a digestive system disease caused by stress and is superior to oral absorption.

The invention discloses a pure plant-fermented yogurt and a production method thereof. The pure plant-fermented yogurt produced by reasonably proportioning grain and oil crop seeds as raw materials and adopting thermal-fusion pulping and lactobacillus plantarum fermentation without adding stabilizers and animal proteins has the advantages of fine and smooth tissues, uniformity and consistence, no sediment and demixing and unique flavor, and is in a thickened fluid; the acidity pH of the pure plant-fermented yogurt is 3.5-4.0, the viable count is not less than 1 million / milliliter, and the production method saves the processes of liquefaction and saccharification so that the unique nutrient components of plants are kept. Without containing cholesterols, lactose and preservatives, the pure plant-fermented yogurt is suitable for all people and can be used for preventing and curing hypertensions, hyperlipaemia, cardiovascular and cerebrovascular diseases, diabetes mellitus, obesities and digestive system diseases after long-term drinking.

The invention relates to the field of molecular biology, and discloses a faeces sample stabilizing solution. The stabilizing solution comprises the following components: 0.02M-4M Guanidine thiocyanate, Tris-HCI of which the pH is 5-10 and the concentration is 2-20 M, 0.05-0.1 mM NaCl and 1-15 mM EDTA. According to the invention, the stability of the detected components in the faeces sample can be effectively kept, self-help fetch by a patient at home can be possible, the faeces stabilizing solution cannot be a hindrance to downstream detection (nucleic acid extraction and detection), the mixture of the faeces and the stabilizing solution can directly enter a detection process, greatly facilitates the flexibility of the follow-up treatment process of the faeces sample, and is beneficial to the detection and the treatment of digestive system diseases.

A heteroaromatic methyl cyclic amine derivative represented by formula (IA) or a pharmaceutically acceptable salt thereof is useful for treatment or prophylaxis of diseases such as sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependence, Alzheimer's disease, Parkinson's disease, Huntington's disease, eating disorder, cephalalgia, hemicrania, pain, digestive diseases, epilepsy, inflammation, immune-related diseases, endocrine-related diseases and hypertension, on the basis of an orexin (OX) receptor antagonist activity.

The invention discloses a medicine compound for curing tummy bug, which including following ingredients and proportion: bismuth aluminic acid 100-300 shares, heavy magnesium carbonate 100-600 shares, sodium bicarbonate 100-400 shares, liquorice extractive powder 100-500 shares, frank mouse lippich 1-50 shares, fennel powder 1-50 shares, aloe powder 1-50 shares or / and grassleaved sweetflag rhizome 1-50 shares. It also discloses the manufacturing method for the medicine, the compound medicine is one compound preparation resisting acid and protecting gastric mucosa, it can be applied to cure stomach and duodenum abscess, chronic superficial gastritis, overmuch stomach acid, and nerve indigestion and so on.

The invention relates to a traditional medicine agent used to treat alimentary system disease of children, and relative preparation. The invention uses evodia rutaecarpa, pepper, Cinnamomum cassia, clove and bighead atractylodes rhizome; processes ultra-critical fluid extraction, distilling in steam, and organic solvent extraction, to extract the benzene to be mixed with borneol and litsea cubeba oil, adding some findings to prepare the drug. The inventive drug has the functions as promoting digestion, or the like.

The present invention relates to reduction of side effects of diclofenac or a salt thereof An agent for reducing side effects of diclofenac or a salt thereof which comprises ornoprostil. It is expected that a combination agent of diclofenac or a non-toxic salt thereof and ornoprostil is comparable to even superior to marketed diclofenac tablets or Arthrotec tables in effects and fast-acting property while showing little side effects (particularly digestive disorders, gastric ulcer, diarrhea / vomiting and renal disorder) and exerting excellent antipyretic, analgesic and antiinlfammatory effects. Also, by formulating the combination agent into a preparation of separation type pharmaceutical preparation, the stability of ornoprostil can be improved.

The invention provides a stable compound coenzyme preparation and a preparation method thereof. The main compositions and proportions of the stable compound coenzyme preparation are as follows: 90-120 U of coenzyme A (CoA), 0.1-0.3 mg / ml coenzyme I (NAD), 1-5 mg / ml glutathione (GSH), 1-2.5 mg / ml adenosine triphosphate (ATP), 1.8-12 mu g / ml flavin mononucleotide (FMN), 3-13 mu g / ml flavin adenine dinucleotide (FAD), 0.1-0.4 mg / ml adenosine diphosphate (ADP), 0.2-0.4 mg / ml adenosine monophosphate (AMP), 1.2-15 mu g / ml of adenosine methionine (SAM), 1-5 mg / ml calcium gluconate, 0.5-1.5 mg / ml cysteine hydrochloride, and 0.6-5 mg / ml mannitol. The preparation method overcomes the defects that high-speed centrifugalization is adopted, freeze-drying conditions are not clear and the product stability is poor in the existing method, and the stable compound coenzyme preparation is widely applied to the practices of preparing drugs for treating cardia-cerebrovascular diseases and digestive system diseases.

The invention relates to a food additive that includes, relative to the total weight thereof: about 3.5 wt % of capsicum oleoresin containing 6 wt % of a capsaicine and dihydrocapsaicine mixture; about 5.5 wt % of cinnamaldehyde; about 9.5 wt % of eugenol; the balance up to 100% consisting of hydrogenated vegetable oils. The invention also relates to the uses of said additive for improving the daily distribution of food ingestion by animals, for increasing the amount of water drunk by animals, or for preparing a food product intended for the preventive or therapeutic treatment of animal digestive disorders, such as acidosis or bloating. This food additive is particularly adapted for ruminants such as bovine cattle.

The invention discloses a rumen-protected coated enrofloxacin mini-pill and a preparation method thereof, and solves the problems of conventional medicines that animals are easily caused to not ruminate and have digestive disorders. The rumen-protected coated enrofloxacin mini-pill is prepared from the following raw materials by weight: 5-15% of enrofloxacin, 60-80% of an auxiliary material and 10-25% of coating layer. The invention further provides the preparation method for the rumen-protected coated enrofloxacin mini-pill. Through oral medication, a medicinal component is not released in the rumen, and the medicinal component, namely enrofloxacin, is released when being dissolved after reaching the true stomach, so that an antibacterial action is directly played in intestinal tracts; enrofloxacin can also be used for treatment of general infection diseases of mycoplasma, pasteurellosis and the like after being absorbed into blood through intestinal tracts; animal rumination is completely unaffected, and the use is very convenient.

Disclosed is a prebiotic composition comprising a combination of 2′fucosyllactose (2′FL) and isomaltooligosaccharide (IMO). The 2′FL and IMO are present in the prebiotic composition in a weight ratio of from 1:1 to 1:10. The prebiotic composition is effective for use in methods of preventing and / or treating a gastrointestinal (GI) condition in an animal, such as irritable bowel syndrome (IBS), inflammatory bowel disease(s) (IBD), Crohn's disease, and ulcerative colitis (UC). A foodstuff or beverage, a medical food, a nutritional composition, and a kit presentation, each including the prebiotic composition, and each suitable for use in methods of reducing or suppressing inflammation in an animalian tract, are also disclosed. A method of using the prebiotic composition to prevent and / or treat a GI condition in an animal is further disclosed. The method comprises administering the prebiotic composition to the animal.

The present invention provides an agent and a food for the prophylaxis or improvement of a functional gastrointestinal disorder, which contains, as an active ingredient, at least one kind selected from glutamic acid, 5′-nucleotide and a salt thereof.

The invention discloses a closestool type urine and excrement detection robot and a urine and excrement detection robot internet of things system. The urine and excrement detection robot can automatically reach a preset position, provide urination and defecation behavioral monitoring and urine and excrement component detection for the user, and screen urinary and digestive system diseases as soonas possible; equipment maintenance, data processing and medical support are provided through an Internet of Things system, and can also be used in cooperation with a squatting pan or a pedestal pan ofa user, the closestool structure is customized according to the individuation of the user, and therefore efficient, convenient and intelligent urine and excrement detection experience is provided forthe user.

Apparatus and methods for providing therapeutic treatment for symptoms associated with GERD and / or other digestive disorders and / or other medical conditions are described herein. In some embodiments, an apparatus includes a support element that has a first end portion and a second end portion and a top surface disposed at an angle relative to a bottom surface of the support element. The second end portion has a height greater than the first end portion. A riser element is configured to be coupled proximate to the second end portion of the support element. A body element is configured to be disposed on at least one of the support element or the riser element. The body element has a first arm and a second arm connected together by an arc portion.

There is provided methods, kits, combinations, and compositions comprising a Aspergillus oryzae protease enzyme, a Bacillus subtilis protease enzyme, and a Aspergillus niger lipase enzyme for treating a digestive disorder in a subject in need thereof. The methods, kits, combinations, and compositions may also be used along with an agent (or combination of agents) for raising the gastric pH, a digestive enzyme useful in enhancing digestive activity, a dietary supplement, or a pharmaceutical agent.

The invention provides healthcare tea oil and a preparation method thereof. Per 1kg of healthcare tea oil comprises, by weight, 4000-8000 micrograms of beta-carotene, 4000-8000 micrograms of lecithin and 60-130 micrograms of organic selenium. The preparation method includes: subjecting tea seeds to crude extraction to obtain crude tea oil, and then refining the crude tea oil and measuring content of nutritional ingredients; preparing beta carotene mother liquor and lecithin mother liquor; preparing organic selenium mother liquor; according to content standard, adding the beta-carotene mother liquor, the lecithin mother liquor and the organic selenium mother liquor to the refined tea oil to obtain a pre-finished healthcare tea oil product; 5), subjected to the pre-finished healthcare tea oil product to centrifugal purification processing, filtering by an ultrafiltration membrane unit and microwave sterilization to obtain the healthcare tea oil. The healthcare tea oil has healthcare functions of lowering cholesterol levels, protecting the liver and preventing digestive system diseases, wide raw material sources are achieved, and the tea oil is reasonable in price and cost, simple in process, easy to operate and high in promotion value.

The invention discloses a method for processing organic black tea by using high-quality black tea on Sheng Mountain in Heng county in a famous scenic zone in Guangxi province, the processing method comprises the following steps: selecting high-quality natural organic tea with characteristics of no pesticide, no hormone and no chemical medicine pollution in the processing steps, then picking tea-leaves, withering, rolling, deblocking, piling, drying in a heat roller, airing, drying and packaging, wherein whole processing step without pollution is employed. The method is carried out on the condition that an artificial synthesized fertilizer, a pesticide, a plant-growth regulator and a chemical food additive are not used, the organic black tea has the advantages of delicate fragrance and savory and mellow taste, pine needle smell is filled in a tea basement, deterioration can not generated for five years preservation under normal temperature, long-term drinking of the organic black tea has the efficacy for promoting disease recovery of a digestive system and has special efficacy for treating gastric ulcer and flatulence.

The invention discloses a mixed-grain full-nutrition formulation food for patients with gastrointestinal tract malabsorption and pancreatitis, and relates to the technical field of healthcare foods. The food is prepared by mixing millet, corn starch, protolysate powder, lactalbumin, glucose, traditional Chinese medicine extracting liquid, honey, medium-chain triglyceride and stevioside. The food is good in mouth feel, excellent in effect, convenient to eat and suitable for auxiliary treatment of the patients with digestive system diseases such as gastrointestinal tract malabsorption, chronic gastroenteritis, gastric ulcer, duodenal ulcer and pancreatitis, and also can serve as a daily healthcare product for preventing the digestive system diseases.

The present document describes an enzyme formulation comprising an enzyme mixture comprising from about 5% to about 45% (wt / wt) of a fungal protease enzyme; and from about 1.5% to about 50% (wt / wt) of at least one polysaccharide digesting enzyme; in combination with an acceptable pharmaceutical carrier. The present document also describes the use of the formulation of the present invention for the prevention or treatment of digestive disorder.

Provided is a compound useful as an N-type Ca2+ channel blocker. As a result of intensive studies of compounds having an action of blocking N-type Ca2+ channels, the present inventors found that a tetrahydroisoquinoline compound of the present invention having a substituent at the 1-position has an action of blocking the N-type Ca2+ channels, an antinociceptive pain action, an antineuropathic pain action, an abdominal pain-inhibitory action and an opioid-induced constipation-improving action, and the present invention has been completed based on these findings. The compound of the present invention can be used as a pharmaceutical composition for preventing and / or treating various pains such as neuropathic pain and nociceptive pain, headaches such as migraine and cluster headache, central nervous system diseases such as anxiety, depression, epilepsy, cerebral stroke and restless legs syndrome, abdominal symptoms such as abdominal pain and abdominal distension, stool abnormalities such as diarrhea and constipation, digestive system diseases such as irritable bowel syndrome, urinary system diseases such as overactive bladder and interstitial cystitis, etc.

The invention relates to a method for preparing a stable simethicone and alverine combination. The invention further relates to a method for preparing a medicinal composition, in particular to a composition for treating functional digestive disorder with tympanites.

The invention relates to a ranitidine hydrochloride composition tablet medicine for treating digestive system diseases and belongs to the technical field of medicines. The ranitidine hydrochloride composition is composed of ranitidine hydrochloride, calcium hydrogen phosphate, pregelatinized starch, aluminium-magnesium silicate and aerosol, wherein ranitidine hydrochloride is a new crystal form compound, and an X-ray powder differentiation pattern obtained through Cu-Kalpha radioactive measurement is shown as a Figure 1, so that the ranitidine hydrochloride adopted in the ranitidine hydrochloride composition tablet medicine is different from the ranitidine hydrochloride reported in the prior art. Experiments show that the tablet prepared from the ranitidine hydrochloride new crystal form compound can be used for solving the problem that ranitidine hydrochloride is extremely easy to deliquesce, high in possibility of moisture adsorption and colour change and poor in stability, and the composition is simple, so that adverse reactions are greatly reduced, and the stability, pharmaceutical effect and biological availability of a tablet preparation are improved.

The invention discloses a digestive tract focus auxiliary identification and positive feedback system based on a cloud platform. The digestive tract focus auxiliary identification and positive feedback system comprises a data collection device, a cloud platform, an online error correction module and an online optimization module, wherein the data collection device is configured to collect a to-be-identified digestive tract image and transmit the to-be-identified digestive tract image to the cloud platform; the cloud platform is configured to establish an inference model, construct a training set to perform optimization training on the inference model, utilize the inference model to carry out alimentary canal position and lesion type inference on the received image, and respectively store the image and digestive tract focus identification results; the online error correction module is configured to check an inference result online and mark and correct the wrongly inferred result for a doctor client; and the online optimization module is configured to add a corrected image into the training set and train the inference model again. According to the digestive tract focus auxiliary identification and positive feedback system, the accuracy of digestive tract focus identification can be improved, and the detection rate of digestive system diseases is improved.

The invention discloses a Chinese patent medicine for coordinating intestines and stomach. The Chinese patent medicine is composed of the following raw materials in parts by weight: 10-15 parts of fructus forsythiae, 8-16 parts of red dates, 6-8 parts of folium sennae, 2-4 parts of coix seeds, 2-3.5 parts of cryptotympana atrata, 1.5-2.5 parts of poria cocos, 2-6 parts of hawthorn, 3-4 parts of honeysuckle, 3-6 parts of tangerine pith, and 0.5-0.8 part of saffron crocus. The Chinese patent medicine disclosed by the invention has a special curative effect on various gastrointestinal diseases and digestive system diseases, as well as is low in toxic and side effects, short in treatment course, and capable of achieving the purpose of thoroughly curing gastrointestinal diseases; and in particular for old gastrointestinal diseases, the Chinese patent medicine can be prepared into decoction, powder or capsules for taking by conventional methods as needed, can be effectively used for treating gastrointestinal diseases, dysentery and the like, as well as is capable of delaying senescence, enhancing immunity, resisting cancer, preventing cancer and beautifying, and removing wrinkles and increasing body scent in case of being used for a long time. The Chinese patent medicine is a great healthcare product and has a very wide development and application prospect.