The invention relates to a preparation method of a water-soluble blue printing dye. The method includes the following steps of 1, dissolving M acid in water, adding
bromamine acid, controlling pH to main within 8.0-8.5, raising the temperature to 70-80 DEG C for conducting a first
condensation reaction, and adding a
solid-supported catalyst in batches during the
condensation reaction, wherein themolar ratio of M acid to
bromamine acid is (1.8-2.2):1; 2, after the first
condensation reaction is completed, adding water and diatomaceous earth and conducting stirring and filtering, adjusting thepH of the filtrate to 1.5-2.0, conducting filtering again, and adjusting the pH of the filtrate to neutrality to obtain a blue-based intermediate liquid; 3, after
cyanuric chloride is subjected to icebath, beating and dispersion, adding the blue-based intermediate liquid, controlling the temperature to main within 3-8 DEG C and the pH to more than 6.0, and conducting a second condensation reaction; 4, after the second condensation reaction is completed, adding a mixture of m-aminobenzenesulfonic acid and p-aminobenzenesulfonic acid, raising the temperature to 40-45 DEG C, maintaining the pH within 6.0-7.0, and conducting a third condensation reaction to obtain raw pulp of the
blue dye. The method can solve the problem that a large amount of high-COD high-salt
colored wastewater is produced by traditional
salting-out refining methods.