383 results about "Pyrazolone" patented technology

Compounds of formula Iare useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

The invention discloses a quantitative detection method of polysaccharide containing uronic acid. The method comprises the following steps: preparing a standard polysaccharide solution and a sample solution to be tested; hydrolyzing polysaccharide in the standard solution and the sample solution to be tested so as to obtain hydrolyzed residue; derivatizing the residue with 1-phenyl-3-methyl-5-pyrazolone to prepare a sugar derivative; carrying out chromatographic analysis on the sugar derivative by the utilization of a high performance liquid chromatograph and a triple quadrupole linear ion trap mass spectrometer; determining which kind of polysaccharide containing uronic acid the sample to be tested is according to the chromatogram; and preparing a standard curve of chromatographic peak area and polysaccharide concentration according to the chromatogram of the standard polysaccharide disaccharide derivative obtained by high performance liquid chromatography-mass spectrum, and calculating content of polysaccharide containing uronic acid in the sample to be tested by the utilization of peak area of the sample to be tested. According to the method provided by the invention, quantitative detection of polysaccharides can be accurately carried out, and effective means is provided for quality control of products such as medicines, health product and the like of the polysaccharides.

The invention discloses a method for determining and correcting cyanide. The method is characterized by comprising the following steps of: 1) putting 10 milliliters of distillate in a colorimetric tube which has a volume of 25 milliliters and is provided with a plug; 2) adding 5 milliliters of phosphate buffer solution into the tube, mixing uniformly, quickly adding 0.2 milliliter of chloramine solution, immediately inserting the plug, mixing uniformly and placing for 3 to 5 minutes; 3) adding 5 milliliters of isonicotinic acid-pyrazolone mixed solution into the tube, uniformly mixing, adding water to dilute until mixture reaches a marked line, shaking uniformly, and placing in an aqueous solution at the temperature of between 25 and 35 DEG C for 40 minutes; and 4) determining absorbance by using a cuvette with height of 1cm, and using reagent blank as reference at the wave length of 638nm, and finding out the corresponding cyanide content from the standard curve. By using an intermediate medium, the cost of purchasing, storing and managing toxic and dangerous chemicals is reduced, and potential unsafe factors of the toxic and dangerous chemicals in using operation can be reduced.

Laser ray transmitting colored thermoplastic resin composition containing a dis-azo salt forming dye consisting of an anionic component from a dis-azo acid dye and an organic ammonium component, said acid dye being represented by Formula (1) below,R1—N═N-E-N═N—R2;   (1)E: (2), (3), (4); R1, R2: aryl, pyrazolone; one or more of E, R1, R2 have sulfonic acid group,R3, R4: hydrogen atom, alkyl, sulfonic acid group,R5, R6: hydrogen atom, sulfonic acid group,R15: sulfonic acid group.Method of laser welding wherein a contact portion of a laser ray transmitting material comprising the laser ray transmitting colored thermoplastic resin composition above and a laser ray absorbing material is welded by irradiating laser ray so that the laser ray passes through the laser ray transmitting material and is absorbed in the laser ray absorbing material with the laser ray transmitting material and the laser ray absorbing material in contact with each other.

The reaction of pyrazolones and methyleneindolines with orthoformates is an ideal one-step method for the preparation of asymmetric methine dyes.