168 results about "AMINO ACID PREPARATION" patented technology

The invention provides an active amino acid water-soluble fertilizer. The fertilizer is composed of the following components in parts by weight: 480-836 parts of an active compound amino acid preparation, 210-410 parts of a compound amino acid microelement chelate, 8-16 parts of a plant nutrient element and 14-26 parts of a plant activator, wherein the effective components of the active compound amino acid preparation comprise L-amino acid with biological activity and bioactive peptides, and the compound amino acid microelement chelate is formed by chelating the active compound amino acid with the microelements in proportion. The invention also provides a preparation method and an application of the fertilizer. Agricultural resources are used as the main raw materials to prepare a new generation of the environmentally friendly amino acid fertilizer by biological fermentation technology, and the fertilizer is applied to the plants, with good plant absorption efficiency. The fertilizer takes effect quickly and has obvious effects of initiating roots, promoting seedlings, strengthening rods, increasing the resistance ability, preventing cracking and increasing the yield and the quality; and moreover the fertilizer is safely applied, and widely used in green organic agriculture and agricultural facilities.

The present invention belongs to the field of medicine and health care article amino acid, and includes pre-treatment of the fermented liquid to eliminate thallus, partial protein, pigment and polysaccharide, controlling the pH value of the fermented liquid after pre-treatment; electrodialysis to eliminate inorganic salt and regulating pH value again; leading in processed OH type anionic exchangecolumn to adsorb impurities and separate glutamine; decoloring, vacuum concentration, isoelectric crystallization, washing coarse crystal in organic solvent and drying. The said process has low exchange resin consumption, no conversion of glutamine in strong acid and strong alkali environment, low production cost and high total glutamine extracting rate up to 70%, and is suitable for industrial production.

The invention relates to recombinant microorganisms which, in comparison to the starting organism, have a higher concentration or activity of a D-amino acid oxidase, of an L-amino acid dehydrogenase, of an NADH cosubstrate regenerating enzyme and, if necessary, of a catalase. The invention also includes methods for preparing L-amino acids from D-amino acids using of these microorganisms.

Alkyl phosphonates prepared from amino acids suitable for use in inhibiting scale. The phosphonates are obtained as reaction mixtures where the level of alkyl phosphonation is deliberately controlled to provide only partial alkyl phosphonation of the amino acid. The resulting alkyl phosphonates exhibit improved environmental properties compared to the fully substituted species, while still exhibiting acceptable efficacy in the control of scale. The compositions possess advantages over existing phosphonates in that they exhibit higher biodegradation by method OECD 306. They also offer lower toxicity to marine life compared to the fully substituted species and are not expected to bioaccumulate.

The invention discloses a method for producing amino acid organic micronutrient fertilizer. The product produced by the method is amino acid chelated microelement that can be directly absorbed by plants. The process extracts amino acid and microelement from various waste materials through one-step preparation The raw materials used are: compound amino acids, medium and trace elements (calcium chloride, magnesium sulfate, borax, copper sulfate, ferrous sulfate, manganese sulfate, zinc sulfate, ammonium molybdate), 10% sodium hydroxide aqueous solution , lignin, controlled release agent. Compared with the prior art, the present invention has the following advantages: industrialized utilization of various waste materials, turning waste into treasure, and protecting the ecological environment; low cost of producing amino acid organic micronutrient fertilizers, and good social benefits; simple production process, no need to add important equipment, easy operation Convenient and easy to promote.

The present invention provides a tablet which comprises a water-absorbent amino acid and a coating agent which is soluble in ethanol and hardly soluble in water. The tablet of the present invention is useful as amino acid preparations for sports, dieting, or pharmaceuticals, and also useful as nutritional supplements, pharmaceuticals and the like in order to supply nutritious of amino acids effective to human health maintenance, or enhance physiological activity of human tissues.

The invention relates to a method of amino-acid with hydrolysis of organic acid or mixed acid (mixing an organic acid and hydrogen chloride with different proportion based on various salt-containing of different products), including the following steps: (1) pre-treatment of raw material; (2) hydrolysis, neutralization; (3) produced amino-acid solution after blending and filtration; (4) going to market after sterilizing, filling in tins, labelling, inspecting and packing. More steps needed for producing amino-acid powder: after adding additives and fillings needed, dissolving, stirring, appropriate concentrating and drying in drying machine, the amino-acid powder is produced, then going to market after packing, labelling, inspecting and packing in boxes. Based on different kind of raw material hydrolysis animal albumen (HAP) and hydrolysis plant albumen (HVP) and various kind of amino-acid preparation may be made with amino-acid. The amino-acid met pharmaceutical grade may be provided as raw material of amino-acid injection solution.

The invention provides fermented feed special for piglets and a preparation method thereof. The fermented feed special for the piglets comprises the following components: 25-35 wt% of corn powder, 20-35 wt% of fermented soybean meal, 5-7 wt% of fish meal, 3-5 wt% of spray dried fish soluble protein powder, 2-3 wt% of spray dried blood meal, 2-5 wt% of compound enzyme preparation, 4-5 wt% of complex amino acid preparation, 8-12 wt% of low-protein whey powder, 5-10 wt% of lactose, 3-5% of sucrose, 1-2 wt% of glutamine, 0.05-0.1 wt% of xylo-oligosaccharide, 0.2-0.5 wt% of zinc oxide, 0.1-0.2 wt%of copper sulfate and 0.1-0.2 wt% of calcium carbonate. The fermented feed overcomes the disadvantage that the digestive enzyme in the piglets are not enough, balances the microbial community in the piglets, improves the resistance of the piglets, and has good diet-induced effect.

Methods and compositions for amino acid production using genetically modified bacteria are disclosed.

The invention discloses an amino acid preparation applied to aquatic products, as well as a preparation method and an aquatic feed thereof. The amino acid preparation is an amino acid microcapsule preparation which contains an amino acid raw material and an auxiliary capsule material and is prepared by using a microcapsule preparation preparing method. The preparation method comprises the following steps of: (1) preparing the amino acid raw material and the auxiliary capsule material; (2) melting the auxiliary capsule material; (3) carrying out high-speed emulsification on the molten auxiliary capsule material and shearing and stirring the auxiliary capsule material; (4) keeping the warm of the mixture and spraying the mixture so as to prepare microcapsule grains; and (5) cooling, sieving and collecting so as to prepare an amino acid microcapsule preparation product. The aquatic feed is an aquatic feed into which the amino acid microcapsule preparation is added. The amino acid preparation is good in slow-release capability, unique in controlled release, good in anti-water-solubility loss and good in free-running property, can effectively prompt the synchronous absorption of exogenous amino acid and protein amino acid in the feed, and has the characteristics of low formula cost, high culture benefit and small influence on culture water environments.

The invention relates to a new microbe Bacillus fordii MH602 strain which can simultaneously produce hydantoinase and L-N-carbamyl hydrolase, hydantoinase produced by strain, L-N-carbamyl hydrolase gene and an application for preparing serial optical pure L-amino acid through the strain. The hydantoinase and L-N-carbamyl hydrolase that are produced by Bacillus fordii MH602 strain can overcome the defect of worse activity and heat stability of hydantoinase and L-N-carbamyl hydrolase in the L-amino acid procedure prepared by prior biologically inverted DL-5 substitution hydantoin or N-hydantoin amino acid, which is all provided with wide substrate spectrum, can catalyze a plurality of substrates and has better substrate selectivity for aromatic hydantoin. The applying operation for preparing L-amino acid by Bacillus fordii MH602 is simple and stable in operation, good in repeatability, which realizes stable and cheap preparation of L-amino acid and is beneficial to do large-scale preparation.

The invention belongs to the technical field of preparation of carbon nano materials, and specifically relates to a method of preparing a carbon nanoparticle with high luminous intensity by organic acid and amino acid. The preparation method comprises the following specific steps: mixing and uniformly grinding the organic acid and amino acid solids in a mortar, adding the mixed and grinded organic acid and amino acid solids into a polyhydric alcohol solvent to prepare mixed liquor; and then, transferring the mixed liquor into a reaction kettle, carrying out solvothermal reaction for 3 hours-6 hours under the condition of 120 DEG C-180 DEG C, and naturally cooling the reaction kettle to the room temperature to obtain carbon nanoparticle liquor. The prepared carbon nanoparticle is uniformly spherical in morphological structure, and has a particle size of 10 nm-30 nm. According to the preparation method disclosed by the invention, raw materials for preparing the carbon nanoparticle are cheap, steps are simple, conditions are gentle and controllable, and the prepared carbon nanoparticle is high in luminous intensity and good in stability. And meanwhile, the carbon nanoparticle is rich in carboxyl on surface, can be directly connected with biomolecules, and has a wide application prospect in the fields such as biological medical detection, cell and tissue imaging.

The invention relates to a hair dye and particularly relates to a natural durable hair dye prepared from iridoid and amino acid and a hair dyeing method. The hair dye provided by the invention contains an agent A, an agent B and an agent C, wherein the agent A contains 8-12% of amino acid, 1.0-5.0% of thickening agent, 0.5-1% of vitamin C and the balance of water, and the pH value of the agent A is adjusted to 8-10; the agent B contains 2-5% of iridoid, 1.0-5.0% of thickening agent, 2-4% of phenethyl alcohol and the balance of water; the agent C contains 3-12% of hydrogen peroxide, 1-5% of thickening agent and the balance of water. The hair dyeing method comprises the steps of firstly, discoloring hair, and then, washing and drying; then, uniformly coating the agent A on the hair, and keeping at the temperature of 30-35 DEG C for 15-25min; next, uniformly coating the agent B on the hair, and keeping at the temperature of 30-35 DEG C for 15-25min; finally, uniformly coating the agent C on the hair, keeping at the temperature of 30-35 DEG C for 20-25min, washing and drying the hair. No substances capable of generating toxicity to human bodies are generated in preparation and application processes of the hair dye; the hair dye is good in safety, capable of dyeing the air into various colors such as black, red, yellow, purplish red and the like, plentiful in dyed colors and favorable in fastness.

The invention belongs to the field of smoke gas treatment and discloses a treatment process for smoke gas produced by an amino acid preparation process. The treatment process comprises the following steps: preparing a chemical preparation, preparing a microbial preparation, removing dust, defogging, desulfurizing, denitrating and preparing a compound fertilizer. The treatment process is simple, unique in design and capable of effectively removing various pollutants and preparing the fertilizer, so that dual purposes are achieved simultaneously.

The invention provides a practical method for preventing the fading of monascus red pigment, and a method for dyeing food, cosmetics and medicines by use of monascus red pigment with an excellent anti-fading effect. The method for preventing the fading of monascus red pigment is characterized in that: the monascus red pigment is dissolved in 0.1% solution of tryptophan, histidine, tyrosine or methionine to prevent the fading of monascus red pigment. The monascus red pigment is dissolved in 0.1% solution of tryptophan, histidine, tyrosine or methionine to form a monascus red pigment-amino acid preparation. The method provided by the invention can effectively prevent the fading of the monascus red pigment caused by illumination; and meanwhile, since the amino acid solution is used for preventing the fading of monascus red pigment, the monascus red pigment-amino acid preparation is very safe to a human body.

The invention relates to natural seasoning paste which is prepared from, by mass, 5-20 parts of natural seasoning, 70-80 parts of hydrolyzed plant protein fluid, 1-10 parts of I+G, 5-10 parts of salt, 5-10 parts of white granulated sugar, 1-5 parts of yeast extracts, 0.1-2 parts of essence and 1-15 parts of thickener. The natural seasoning paste is prepared in the mode that chicken, duck, fungi and other delicious substances are effectively extracted through boiling and biological enzymolysis and collagen of marrow in livestock bones is hydrolyzed into peptide and amino acid. The seasoning paste is a pasty seasoning similar to oyster sauce and is rich in taste, natural products are adopted as preparation raw materials and have no side effects on human bodies, and the natural seasoning paste can be used for flavoring of various soups and dishes and is wide in application range and wide in application prospect.

The invention discloses a preparation method of simulated tobacco shreds and a method for analyzing and researching the maillard reaction in a cigarette tobacco shred drying procedure by using the simulated tobacco shreds. The preparation method is characterized in that the simulated tobacco shreds which do not contain maillard reaction products are prepared from filter paper, reducing sugar and amino acid which serve as raw materials, and the tobacco shreds are used for researching the maillard reaction in the cigarette tobacco shred drying procedure. The preparation method has the advantages that (1) the filter paper with the character similar to that of tobaccos is used as a matrix, and the reducing sugar and the amino acid are added to prepare the simulated tobacco shreds which do not contain intermediate products and final products of the maillard reaction and can avoid interference caused by the maillard reactionproducts contained in tobaccos and enable the research on the maillard reaction in the tobacco shred drying procedure to be more accurate and targeted; (2) by setting of the types and ratios of the reducing sugar and the amino acid, a system pH, a heating condition and the like, a model system with different reaction conditions is obtained, and the influence of various reaction factors on the maillard reaction in the tobacco shred drying procedure can be inspected respectively.

The invention relates to a compound amino acid preparation for hemodialysis and a hemodialysis preparation containing the same. The invention provides a preparation for modulating disorder of plasma aminogram of hemodialysis patients by using a plurality of essential amino acids and semi-essential amino acids, specifically relates to a solid powder form or liquid bicarbonate hemodialysis preparation used for treating nephrosis and containing compound amino acids, and especially to a hemodialysis preparation containing L-leucine, L-isoleucine, L-valine, L-threonine, L-phenylalanine, L-methionine, L-tryptophan, L-lysine, L-histidine, L-arginine and a pH conditioning agent (e.g., acetic acid, citric acid, malic acid, lactic acid and hydrochloric acid) and a preparation method thereof. The hemodialysis preparation further contains sodium chloride, potassium chloride, calcium chloride, magnesium chloride and sodium bicarbonate, and can also include glucose. Compared to conventional bicarbonate hemodialysis preparations, the preparation provided in the invention has the advantages of partly modulating disorder of plasma aminogram of hemodialysis patients and reducing side effects in hemodialysis treatment.

The invention discloses a method for integrally preparing compound amino acid by using superfine grinding enzymolysis, and belongs to the technical field of a preparation method of the compound amino acid. The method comprises the following process steps of: 1) cleaning protein raw materials, removing impurities of the protein raw materials and drying for later use; (2) mixing the protein raw materials obtained in the step 1) with water; adding into a constant-temperature superfine grinding system; simultaneously adding proteolytic enzyme; and performing grinding enzymolysis on the protein raw materials; and 3) putting the materials obtained in the step 2) into a centrifugal machine for carrying out centrifugal separation; and spraying and drying supernate to obtain compound amino acid powder. The method is reasonable in design; the protein raw materials are subjected to earlier stage treatment and are treated by using a combined technology of mechanical force superfine grinding and enzymolysis; a condition of the constant-temperature superfine grinding system and a condition of the enzymolysis are reasonably controlled at the same time; and the protein raw materials are subjected to after-treatment, so that the environment-friendly low-carbon requirement is met, and the pollution and the hazard are avoided; and therefore, the prepared compound amino acid is a preferable fertilizer carrier to develop green organic agriculture.

The invention relates to a coating material used for rumen by-pass amino acid preparation, including soybean wax, stearic acid, fatty acid, ethyl cellulose, polyethylene glycol and a pH sensitizer. The invention also relates to a rumen by-pass amino acid preparation, which includes the coating material disclosed by the invention and one or more of amino acids. The invention also relates to a preparation method a rumen by-pass amino acid preparation. The preparation method comprises the steps of 1) using one or more amino acid as core material; and 2) coating a core material by using the coating material disclosed by the invention.

The invention belongs to the fields of genetic engineering and enzyme engineering, and relates to a one-step method for synthesizing gamma-aminobutyric acid by using recombinant corynebacterium crenatum (C.crenatum) and with glucose as a substrate. According to the method, a genetic engineering method is adopted, C.crenatum SYPA5-5 gene argB is knocked out, such that a safe strain C.crenatum E01 which can accumulate glutamic acid is obtained; a glutamic acid decarboxylase gene is cloned from L.Plantarum GB01-21 and is expressed in the C.crenatum E01, such that recombinant C.crenatum E01 / pGAD used for directly synthesizing gamma-aminobutyric acid with glucose as a substrate is obtained. A recombinant strain fermentation broth gamma-aminobutyric acid accumulation reaches 13.98g / L. According to the invention, glutamic acid and gamma-aminobutyric acid metabolic pathways are successfully integrated, such that one-step production from glucose to gamma-aminobutyric acid is realized. Therefore, preparation method is simplified, cost is reduced, safety is improved, and novel idea is provided for high-efficiency and low-cost amino acid preparation.

The invention discloses an amphipathic oligomeric polypeptide drug conjugate. According to the amphipathic oligomeric polypeptide drug conjugate, a drug can be directly condensed with a carboxyl at the terminal C of oligomeric polypeptide through a hydroxy or an amino in the chemical structure, so as to form an ester bond or an amido bond, or the drug can be condensed with an amino at the terminal N of oligomeric polypeptide through a carboxyl in the chemical structure, so as to form the amido bond, or the drug can be bonded with oligomeric polypeptide through certain link molecules. The drug conjugate has the advantages that oligomeric polypeptide which is prepared from high-safety amino acid is adopted as a main building material, and can be coupled with an anti-inflammatory drug for preparation of the amphipathic oligomeric polypeptide drug conjugate; compared with the conventional preparation, the amphipathic oligomeric polypeptide drug conjugate has the advantages of high safety and drug carrying capacity because the drug can be directly bonded with a carrier material; when the amphipathic oligomeric polypeptide drug conjugate enters a human body, the effect of the drug can be exerted for a long time.

The invention provides a pork pig fermented feed and a preparation method thereof. The pork pig fermented feed consists of the following components in percentage by weight: 20-35 percent of corn flour, 20-35 percent of fermented soybean meal, 5-7 percent of dephenolized lintless and non-hull cottonseed meal, 5-7 percent of fish meal, 3-5 percent of spray dried plasma protein, 2-3 percent of spray dried blood flour 2-5 percent of composite enzyme preparation, 2-5 percent of composite amino acid preparation, 8-12 percent of low-protein whey powder, 5-10 percent of lactose, 3-5 percent of sugar, 1-2 percent of glutamine, 0.2-0.5 percent of zinc oxide, 0.1-0.2 percent of copper sulfate and 0.1-0.2 percent of calcium carbonate. According to the pork pig fermented feed, the disadvantage of insufficient digestive enzyme in pork pigs can be overcome, the microbial floras in the pork pigs are balanced, the resistance of the pork pigs is enhanced, and a good feeding promotion effect is achieved.

The invention belongs to the technical field of amino acid preparation, and particularly relates to a method for producing lysine and feed. The method comprises the following steps of (1) preparing a culture medium and performing fermentation: inoculating 10% of mixed bacterial liquid into a seed culture medium, and performing culture to prepare seed liquid; inoculating 10% of the seed liquid to a fermentation culture medium, and performing aerobic fermentation to prepare fermented liquid; (2) performing filtration sterilization: performing filtration sterilization on the fermented liquid through an ultrafiltration membrane, and collecting concentrated liquid and penetrating liquid; (3) preparing feed: adding the concentrated liquid obtained in the step (2) to pre-prepared feed, and performing stirring to obtain the lysine and the feed; and (4) extracting the lysine: performing decolorization, concentration and crystallization on the penetrating liquid obtained in the step (2) to obtain the lysine. According to the method, mixed fermentation strains are mixed reasonably, so that the synergistic effect is good and the fermentation efficiency can be greatly improved; and the lysine and the high-protein feed product are produced at the same time, so that the production cost is greatly reduced.

The invention discloses a novel soluble fertilizer with a humic acid biological activity. The novel soluble fertilizer comprises the following components: 8-15wt% of potassium humate, 5.6-10.5wt% of diammonium phosphate, 5-8.8 percent of urea, 3.8-5.6wt% of boric acid, 3.8-12.5wt% of monopotassium phosphate, 2.8-4.5wt% of active compound amino acid preparation, 0.5-1.5wt% of plant active agent, and 57.5-75.5wt% of water. The novel soluble fertilizer has three effects of nutritional supplement, antibiosis and virus resistance, and has the advantages of effectively improving soil, being durable in fertilizer effect, enabling the root system of the plants to be developed, enhancing the disease resistance, effectively improving the crop quality, having an effect of preserving moisture and fertility, activating immobilized nutrients in soil so as to ensure that sufficient nutrients can be obtained for the crops in the whole reproductive period, preventing premature senility, and prolonging the picking period.

The invention relates to an amino alcohol preparation method using aqueous amino acid as a raw material. The method employs a catalyst; and amino acid in aqueous solution or in a mixed solution of water and other solvent is reduced by hydrogen under catalyst effect, so as to synthesize amino alcohol through a one step method. The method has characteristics of simple steps, short production period, little pollution and low production costs, etc.

The invention discloses an amphiphilic oligopeptide drug conjugate. Hydroxyl or an amino group of the chemical structure of a drug and a carboxyl group at the end C of oligopeptide directly undergo a condensation reaction to produce an ester bond or an amido bond, or a carboxyl group of the chemical structure of a drug and an amino group at the end N of oligopeptide undergo a condensation reaction to produce an amido bond, or a certain bonding molecule of a drug and oligopeptide are bonded. Oligopeptide prepared from high-safety amino acids is used as a main construction material and is coupled with an anticancer drug so that the amphiphilic oligopeptide drug conjugate is prepared. Compared with the traditional preparation, the amphiphilic oligopeptide drug conjugate has good safety and a high drug loading capacity because of direct bonding of the drug and a carrier material, and can produce drug effects for a long time after entering into the human body.

The invention discloses an unsaturated ester prepared from an amino acid which takes threonine as a representative and contains hydroxyl groups. The invention further discloses a preparation method of the unsaturated ester shown in the specification. The preparation method comprises the following steps: modifying an unsaturated carboxylic acid with the amino acid, carrying out an esterification reaction so as to esterify the threonine containing hydroxyl groups by virtue of the unsaturated carboxylic acid, and feeding carboxyl groups, amino groups and sulfonic groups into the hydroxyl groups of the amino acid so as to synthesize an unsaturated amino acid ester.

An albumin preparation that prevents onset of hepatic encephalopathy caused by conventional amino acid preparations and enhances an effect of improving the symptoms is provided. The albumin preparation containing amino acids is characterized in that a content of albumin is 0.01 to 1.0 w / v %, a content of plurality of amino acids containing branched amino acid is 5 to 10 w / v %, a content of the branched amino acids is equal to or more than 30 w / w % on the basis of the content of total amino acids and further, the Fischer ratio (branched amino acid / [phenylalanine+tyrosine] (molar ratio)) is equal to or more than 20.