The invention provides an
ibuprofen oral suspension comprising the following ingredients based on the concentration:
ibuprofen of 20 to 40 g / L and dispersion
cellulose of 13 to 30 g / L. The preparation method of
ibuprofen oral suspension comprises the following steps: (1) heating glycerine, adding a
preservative; (2) adding the dispersion
cellulose into water, then dispersing uniformly; (3) mixing pure water with a
wetting agent; (4) thoroughly mixing a sweetener, a
flavouring agent and the
preservative solution which is prepared in the first step with the suspension
system which is obtained in the second step; (5) mixing a micronized ibuprofen with the dispersion solution which is obtained in the third step uniformly, then adding the mixture obtained therein into the mixture obtained in the fourth step, and then stirring at high speed and simultaneously infusing
nitrogen to obtain an ibuprofen oral suspension. The ibuprofen oral suspension provided by the invention is a thixotropic
colloid comprising ibuprofen particles which are arranged evenly, and is characterized in that the ibuprofen oral suspension can be changed to a low-
viscosity liquid by shaking before taking, the problem of common suspension which has high
viscosity and agglomeration after placing for a long time is improved, the accuracy of dosage is ensured and the stability of the ibuprofen oral suspension is good.