38results about How to "The process is simple and environmentally friendly" patented technology

The invention relates to a method for preparing a sweetening agent sucralose by a one-pot process. The method comprises the following steps of: protecting sucrose which is taken as a raw material by sucrose-6-hydroxyl through boron anhydrous with presence of an acid catalyst and a solvent, directly implementing a chlorination through thionyl chloride without separating disucrose borate which is an intermediate product to obtain hexachloro disucrose borate, and hydrating to obtain the sucralose. The method disclosed by the invention sequentially implements three reactions, namely selective protection, chloro reaction and hydration, of the sucrose-6-hydroxyl in one pot to prepare the sucralose, and the process is simple and convenient and reduces discharge of wastewater; and the prepared sucralose product is high in purity, high in yield, low in cost, and suitable for industrial production.

The invention discloses a method for preparing metandienone. The method comprises the following steps: dissolving mestanolone into an organic solvent, performing a reaction with bromine for 4-6 hours in a strong acid solution, and performing bibromination at a 2,4 site of mestanolone molecules so as to obtain 2,4-bibromine mestanolone; further dissolving the 2,4-bibromine mestanolone into an organic solvent, performing a reaction for bidebromination with a debromination agent for 2-6 hours, and implementing two steps of reactions to synthesize a crude product of metandienone; decoloring the crude product with activated carbon in low-carbon alcohol less than C4, and performing recrystallization, thereby obtaining a methyltestosterone product, wherein the content of HPLC is 99.0-99.5%, the melting point is 162-167 DEG C, and the total yield of a synthesis weight is 75-78%. The method disclosed by the invention has the advantages of being wide in raw material source, short in synthesis route, simple, convenient and environmentally friendly in process, high in product yield, good in quality, and the like, the production cost of the method is reduced by 30-35% when being compared with that of a conventional method, the solvent can be recycled and repeatedly used, and thus the method is both economic and environmental-friendly and is very beneficial to industrial production.

The invention provides a method for preparing a metandienone product. The method comprises the following steps of: crystallizing and separating deodorized distillates in production of soybean oil to obtain phytosterol, carrying out microbial fermentation on the phytosterol by adopting a nutritional culture medium and one or more microorganism bacteria to obtain 1,4-androstadienedione, i.e. IDD, then preparing metandienone in the presence of methylmagnesium halide, an organic solvent and acid by using the IDD as a raw material, and refining the metandienone to obtain the metandienone product. The metandienone is prepared by adopting the IDD as the raw material; and compared with a traditional method adopting diosgenin as the raw material, the method of the invention has the advantages thatthe source of the raw materials is wide, the process is economical and environmentally friendly, and the production cost is greatly reduced. Compared with a traditional production method, the method of the invention has the advantages of short synthetic route, simple and environment-friendly process, high product yield, and good quality; and by calculating at the price of the raw material at present, the cost of the production raw material can be reduced by 40 to 45 percent.