The invention provides a fluorescent probe with functions of detecting
hydrogen peroxide and performing photodynamic killing on
cancer cell activity as well as a preparation method and application thereof, and belongs to the technical field of a biochemical material. The fluorescent probe with the functions of detecting
hydrogen peroxide and performing photodynamic killing on
cancer cell activityhas aggregation induced
luminescence characteristic, can specifically respond to the
hydrogen peroxide, generates a substance with stronger
fluorescence, can be applied to detection on the
hydrogen peroxide in cells, and can selectively position
subcellular organelle lipid droplets in the cells; the product obtained through action between the fluorescent probe and the
hydrogen peroxide has large stokes displacement, so self-absorption can be avoided and background interference can be reduced; the fluorescent probe as well as the product obtained through the action between the fluorescent probeand the
hydrogen peroxide have high light stability and
photobleaching resistance, and are suitable for long-time tracing of the hydrogen peroxide in living cells or living bodies; meanwhile, the product obtained through the action between the fluorescent probe and the hydrogen peroxide has
active oxygen generation capacity, can be applied to photodynamic killing of the
cancer cells and can construct a diagnosis and treatment
reagent integrating diagnosis and treatment functions.