The present invention discloses a cement concrete for the wet connection seam of a system sequentially comprising simply-supported bridge and continuous bridge, and a preparation method thereof, wherein the cement concrete comprises cement, river sand, water, a polycarboxylic acid-based efficient water reducer, rice hull ash, apatite, sericite, sepiolite, a sodium polyacrylate high water absorption resin, talc powder, nanometer calcium carbonate, polyethylene fibers and polyester fibers, and with the synergistic effect among the mineral components such as the apatite, the sericite and the sepiolite and the two fibers, the toughening can be achieved, the impact resistance and the extension ability of the concrete can be improved, and the problems that the wet connection seam concrete is damaged and the bridge surface cracks can be effectively solved. According to the present invention, the cement concrete has advantages of high compressive strength, good toughness, impact resistance, permeation resistance, self-leveling, and the like.